Bulky DNA adducts

ID863
NameBulky DNA adducts
SynonymsDNA adducts
StructureThumb
DescriptionAny chemical bound to DNA.
GroupDNA adducts
Sub-groupDNA adducts
Exposure sourcePollution
Use
CAS number
PubChem ID
ChEBI ID
FooDB ID
HMDB ID

Biomarker measurements

Biomarker concentration values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed asPublication
108110Low exposure (Rural/suburban)Bus drivers in Copenhagen exposed to ambient air pollutionDenmarkDKWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts4747Yes25.9940.57adducts/10^8 nucleotides26.0 adducts/10^8 nucleotidesCrudeAutrup 1999
108120High exposure (City center)Bus drivers in Copenhagen exposed to ambient air pollutionDenmarkDKWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts6049Yes75.42112.04adducts/10^8 nucleotides75.4 adducts/10^8 nucleotidesCrudeAutrup 1999
108130ControlsMail carriers in Copenhagen non-exposed to ambient air pollutionDenmarkDKWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts10297Yes30.8851.84adducts/10^8 nucleotides30.9 adducts/10^8 nucleotidesCrudeAutrup 1999
108140Low exposure - VillageSuburban and village inhabitants near Cotonou non-exposed to urban air pollutionBeninBJWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts173.10.08.0adducts/10^8 nucleotides3.1 adducts/10^8 nucleotidesCrudeAyi-Fanou 2011
108150Low exposure - SuburbanSuburban and village inhabitants near Cotonou non-exposed to urban air pollutionBeninBJWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts202.10.09.0adducts/10^8 nucleotides2.1 adducts/10^8 nucleotidesCrudeAyi-Fanou 2011
108160High exposure - Taxi-motor bike driversCity residents in Cotonou exposed to urban air pollutionBeninBJWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts1324.61.069.0adducts/10^8 nucleotides24.6 adducts/10^8 nucleotidesCrudeAyi-Fanou 2011
108170High exposure - Roadside residentsCity residents in Cotonou exposed to urban air pollutionBeninBJWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts1123.71.076.0adducts/10^8 nucleotides23.7 adducts/10^8 nucleotidesCrudeAyi-Fanou 2011
108180High exposure - Street vendorsCity residents in Cotonou exposed to urban air pollutionBeninBJWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts1634.73.0169.0adducts/10^8 nucleotides34.7 adducts/10^8 nucleotidesCrudeAyi-Fanou 2011
108190High exposure - Gasoline sellersCity residents in Cotonou exposed to urban air pollutionBeninBJWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts1737.24.0124.0adducts/10^8 nucleotides37.2 adducts/10^8 nucleotidesCrudeAyi-Fanou 2011
108280Exposed (Teplice) - GSTM1+Postal workers and gardeners working outdoor in a highly polluted area of Northern BohemiaCzech RepublicCZWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts100.934.012.17adducts/10^8 nucleotides4.0 adducts/10^8 nucleotidesCrudeBinkova 1996
108290Exposed (Teplice) - GSTM1-Postal workers and gardeners working outdoor in a highly polluted area of Northern BohemiaCzech RepublicCZWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts110.814.227.49adducts/10^8 nucleotides4.2 adducts/10^8 nucleotidesCrudeBinkova 1996
108300Controls (Prachatice) - GSTM1+Postal workers and nursery school teachers in a non-polluted area of Southern BohemiaCzech RepublicCZWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts111.054.779.58adducts/10^8 nucleotides4.8 adducts/10^8 nucleotidesCrudeBinkova 1996
108310Controls (Prachatice) - GSTM1-Postal workers and nursery school teachers in a non-polluted area of Southern BohemiaCzech RepublicCZWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts190.613.8616.27adducts/10^8 nucleotides3.9 adducts/10^8 nucleotidesCrudeBinkova 1996
111410ControlsGeneral population in FlorenceItalyITEPIC-Florence (European Prospective Investigation into Cancer and Nutrition)White blood cell DNA32P-Postlabelling methodBulky DNA adducts10085.011.07.7adducts/10^9 nucleotides1.1 adducts/10^8 nucleotides0.8 adducts/10^8 nucleotidesCrudePalli 2001
111420ExposedTraffic-exposed workers in Florence areaItalyITWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts11484.213.711.1adducts/10^9 nucleotides1.4 adducts/10^8 nucleotides1.1 adducts/10^8 nucleotidesCrudePalli 2001
111510Mothers [by smoking status]Mothers and their newborns in Krakow and LimanowaPolandPLdelivery + 5 to 66 hoursWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts12214.215.4adducts/10^8 nucleotides14.2 adducts/10^8 nucleotidesCrudeWhyatt 2001
111520Mothers - Non-smokersMothers and their newborns in Krakow and LimanowaPolandPLdelivery + 5 to 66 hoursWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts7915.016.3adducts/10^8 nucleotides15.0 adducts/10^8 nucleotidesCrudeWhyatt 2001
111530Mothers - Former smokersMothers and their newborns in Krakow and LimanowaPolandPLdelivery + 5 to 66 hoursWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts3213.015.6adducts/10^8 nucleotides13.0 adducts/10^8 nucleotidesCrudeWhyatt 2001
111540Mothers - Current smokersMothers and their newborns in Krakow and LimanowaPolandPLdelivery + 5 to 66 hoursWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts1112.04.2adducts/10^8 nucleotides12.0 adducts/10^8 nucleotidesCrudeWhyatt 2001
111550Newborns [by smoking status]Mothers and their newborns in Krakow and LimanowaPolandPLdeliveryWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts12216.612.5adducts/10^8 nucleotides16.6 adducts/10^8 nucleotidesCrudeWhyatt 2001
111560Newborns - Non-smoking mothersMothers and their newborns in Krakow and LimanowaPolandPLdelivery + 5 to 66 hoursWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts7917.111.3adducts/10^8 nucleotides17.1 adducts/10^8 nucleotidesCrudeWhyatt 2001
111570Newborns - Former smoking mothersMothers and their newborns in Krakow and LimanowaPolandPLdelivery + 5 to 66 hoursWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts3215.714.9adducts/10^8 nucleotides15.7 adducts/10^8 nucleotidesCrudeWhyatt 2001
111580Newborns - Current smoking mothersMothers and their newborns in Krakow and LimanowaPolandPLdelivery + 5 to 66 hoursWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts1114.713.7adducts/10^8 nucleotides14.7 adducts/10^8 nucleotidesCrudeWhyatt 2001
112170RuralRural (agricultural colleges) or urban (University of Aarhus resident in the center of the town) male studentsDenmarkDKLymphocyte DNA32P-Postlabelling methodBulky DNA adducts290.0540.1521.064fmol/ug0.0 umol/gCrudeNielsen 1996
112180UrbanRural (agricultural colleges) or urban (University of Aarhus resident in the center of the town) male studentsDenmarkDKLymphocyte DNA32P-Postlabelling methodBulky DNA adducts730.0370.2053.723fmol/ug0.0 umol/gCrudeNielsen 1996
112190All [Greek]Male residents in AthensGreeceGRWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts170.1220.2851.11fmol/ug0.0 umol/gCrudeNielsen 1996
112480Controls - MalesGeneral population in FlorenceItalyITEPIC-Florence (European Prospective Investigation into Cancer and Nutrition)White blood cell DNA32P-Postlabelling methodBulky DNA adducts5182.48.96.6adducts/10^9 nucleotides0.9 adducts/10^8 nucleotides0.7 adducts/10^8 nucleotidesCrudePalli 2001
112490Controls - FemalesGeneral population in FlorenceItalyITEPIC-Florence (European Prospective Investigation into Cancer and Nutrition)White blood cell DNA32P-Postlabelling methodBulky DNA adducts4987.813.29.7adducts/10^9 nucleotides1.3 adducts/10^8 nucleotides1.0 adducts/10^8 nucleotidesCrudePalli 2001
112500Controls - Urban (Florence)General population in FlorenceItalyITEPIC-Florence (European Prospective Investigation into Cancer and Nutrition)White blood cell DNA32P-Postlabelling methodBulky DNA adducts7185.911.87.3adducts/10^9 nucleotides1.2 adducts/10^8 nucleotides0.7 adducts/10^8 nucleotidesCrudePalli 2001
112510Controls - Suburban (Province)General population in FlorenceItalyITEPIC-Florence (European Prospective Investigation into Cancer and Nutrition)White blood cell DNA32P-Postlabelling methodBulky DNA adducts2982.89.08.1adducts/10^9 nucleotides0.9 adducts/10^8 nucleotides0.8 adducts/10^8 nucleotidesCrudePalli 2001
112520Exposed - MalesTraffic-exposed workers in Florence areaItalyITWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts8181.513.19.7adducts/10^9 nucleotides1.3 adducts/10^8 nucleotides1.0 adducts/10^8 nucleotidesCrudePalli 2001
112530Exposed - FemalesTraffic-exposed workers in Florence areaItalyITWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts3390.915.313.5adducts/10^9 nucleotides1.5 adducts/10^8 nucleotides1.4 adducts/10^8 nucleotidesCrudePalli 2001
112540Exposed - Urban (Florence)Traffic-exposed workers in Florence areaItalyITWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts6288.715.212.6adducts/10^9 nucleotides1.5 adducts/10^8 nucleotides1.3 adducts/10^8 nucleotidesCrudePalli 2001
112550Exposed - Suburban (Province)Traffic-exposed workers in Florence areaItalyITWhite blood cell DNA32P-Postlabelling methodBulky DNA adducts5278.911.99.2adducts/10^9 nucleotides1.2 adducts/10^8 nucleotides0.9 adducts/10^8 nucleotidesCrudePalli 2001
145920ExposedPrimary school boys from schools located in high density traffic areas in BangkokThailandTHLymphocyte DNA32P-Postlabelling methodBulky DNA adducts1070.450.130.341.04adducts/10^8 nucleotides0.5 adducts/10^8 nucleotides0.3 adducts/10^8 nucleotidesCrudeTuntawiroon 2007
145930ControlsPrimary school boys from schools located in provincial area of Chonburi provinceThailandTHLymphocyte DNA32P-Postlabelling methodBulky DNA adducts690.090.050.090.16adducts/10^8 nucleotides0.1 adducts/10^8 nucleotides0.1 adducts/10^8 nucleotidesCrudeTuntawiroon 2007

Intake values

No data available

Correlation values

No data available

Reproducibility values

No data available