JPHC (Japan Public Health Center-based Prospective Study on Cancer and Cardiovascular Diseases) (Cohort)

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ID19
NameJPHC (Japan Public Health Center-based Prospective Study on Cancer and Cardiovascular Diseases)
AcronymJPHC
DescriptionThe JPHC Study (formerly called "Koseisho Multipurpose Prospective Cohort Study") began in 1990 (Cohort I) and 1993 (Cohort II). It covers 11 public health center areas throughout Japan and includes a total of 140 420 residents. The study's design includes a baseline survey with a self-administered questionnaire on lifestyle and collection of blood and health checkup data; a follow-up system for mortality, migration, and incidence of cancer and cardiovascular diseases; an additional follow-up survey after 5 and 10 years; and distribution of a newsletter. The JPHC study is expected to provide evidence for the prevention and control of cancer and cardiovascular diseases in the 21st century.
CountryJapan
PubMed ID11763137
URL
Cohort designObservation

Publications with JPHC (Japan Public Health Center-based Prospective Study on Cancer and Cardiovascular Diseases)

TitleFirst authorYear
Validity and reproducibility of a self-administered food-frequency questionnaire to assess isoflavone intake in a japanese population in comparison with dietary records and blood and urine isoflavonesYamamoto2001
Effect of cooking loss in the assessment of vitamin intake for epidemiological data in JapanKobayashi2011
Single measurement of serum phospholipid fatty acid as a biomarker of specific fatty acid intake in middle-aged Japanese menKobayashi2001
Plasma levels of carotenoids, retinol and tocopherol and the risk of gastric cancer in Japan: a nested case-control studyPersson2008
Plasma 25-hydroxy vitamin D and subsequent prostate cancer risk in a nested Case-Control study in Japan: The JPHC studySawada2017
Plasma vitamin D and risk of colorectal cancer: the Japan Public Health Center-Based Prospective StudyOtani2007
Plasma folate and risk of colorectal cancer in a nested case-control study: the Japan Public Health Center-based prospective studyOtani2008
Plasma isoflavones and risk of primary liver cancer in Japanese women and men with hepatitis virus infection: a nested case-control studyMichikawa2015
Plasma isoflavone concentrations are not associated with gastric cancer risk among Japanese men and womenHara2013
Plasma isoflavones and the risk of lung cancer in women: a nested case-control study in JapanShimazu2011
Plasma tea polyphenol levels and subsequent risk of breast cancer among Japanese women: a nested case-control studyIwasaki2010
Plasma tea polyphenols and gastric cancer risk: a case-control study nested in a large population-based prospective study in JapanSasazuki2008
Plasma isoflavones and subsequent risk of prostate cancer in a nested case-control study: the Japan Public Health CenterKurahashi2008
Plasma isoflavone level and subsequent risk of breast cancer among Japanese women: a nested case-control study from the Japan Public Health Center-based prospective study groupIwasaki2008
Plasma 25-hydroxyvitamin D concentration and subsequent risk of total and site specific cancers in Japanese population: large case-cohort study within Japan Public Health Center-based Prospective Study cohortBudhathoki2018

Biomarker data

Measurements of biomarkers in JPHC (Japan Public Health Center-based Prospective Study on Cancer and Cardiovascular Diseases)

Concentration values

IDParent IDDepthSubject groupPopulationCountryCohortBiomarker Time definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianConverted unitAdjustment typeAdjusted onRegressed onExpressed asPublication

Reproducibility values

IDExcretion IDSubject groupPopulationCountryCohortBiomarker Time definitionBiospecimenAnalytical methodBiomarkerBiomarker detailArithmetic meanGeometric meanMedianUnitAdjusted onReproducibility sizeICCICC 95% CI lowerICC 95% CI upperCV% WSCV% BSVAR WSVAR BSPublication

Associations of biomarkers and exposures in JPHC (Japan Public Health Center-based Prospective Study on Cancer and Cardiovascular Diseases)

Correlation values

IDIntake IDExcretion IDSubject groupPopulationCountryCohortIntake Time definitionIntake Assessment methodIntakeIntake detailSupplement intakes included?Intake Arithmetic meanIntake Geometric meanIntake MedianIntake UnitIntake Adjusted onBiomarker Time definitionBiospecimenAnalytical methodBiomarkerBiomarker detailBiomarker Arithmetic meanBiomarker Geometric meanBiomarker MedianBiomarker UnitBiomarker Adjusted onCorrelation sizeCorrelation typeCorrelation valueCorrelation 95% CI lowerCorrelation 95% CI upperCorrelation p-valueSignificant?Measurement adjustmentDeattenuated?CovariatesPublication

Metabolomic associations

IDIntake IDExcretion IDSubject groupPopulationCountryCohortNo. of subjectsIntake Assessment methodIntakeIntervention doseBiospecimenAnalytical methodBiomarkerStructural identificationFeature selectionArea under curveSensitivitySpecificityPLS-DA VIPBeta coefficientBeta coefficient p-valueANOVA p-valuePublication

Associations of biomarkers and cancer risk in JPHC (Japan Public Health Center-based Prospective Study on Cancer and Cardiovascular Diseases)

Cancer associations

IDExcretion IDSubject groupPopulationCountryCohortNo. of subjectsNo. of casesNo. of controlsBiospecimenAnalytical methodBiomarkerBiomarker detailCancerStudy designPublication

Exposure data

Measurements of exposures in JPHC (Japan Public Health Center-based Prospective Study on Cancer and Cardiovascular Diseases)

Intake values

IDParent IDDepthSubject groupPopulationCountryCohortIntake Time definitionIntake assessment toolIntake food coverageIntake time coverageIntake Assessment methodIntakeIntake detailFood descriptionSupplement intakes included?Measurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianConverted unitAdjustment typeAdjusted onRegressed onExpressed asPublication