KMCC (Korean Multi-center Cancer Cohort) (Cohort)

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ID258
NameKMCC (Korean Multi-center Cancer Cohort)
AcronymKMCC
DescriptionThe Korean Multi-center Cancer Cohort (KMCC-II) is a multi-center prospective cohort designed to investigate the relationship between exposures to environmental factors, lifestyle factors, host factors and the risk of cancer in Korea. Data on general lifestyle, physical activity, diet, reproductive factors, and agricultural exposures have been collected by direct interview since 1993. Anthropometric measurements and some clinical laboratory findings have also been recorded. This cohort is characterized by the exclusion of cancer cases at the time of recruitment through cancer screening by physicians. Of the KMCC-II, 11 045 subjects who have donated their blood and/or urine sample were classified as the KMCC-I. Study participants were recruited voluntarily from 1993 to 2004 from 4 rural and urban areas in Korea. Cancer cases were identified and linked to the Korea Central Cancer Registry as well as the National Death Certification databases.
CountryKorea, Republic of
PubMed ID12718614
URL
Cohort designObservation

Publications with KMCC (Korean Multi-center Cancer Cohort)

TitleFirst authorYear
Plasma phytoestrogens concentration and risk of colorectal cancer in two different Asian populationsKo2018
Isoflavones from phytoestrogens and gastric cancer risk: a nested case-control study within the Korean Multicenter Cancer CohortKo2010

Biomarker data

Measurements of biomarkers in KMCC (Korean Multi-center Cancer Cohort)

Concentration values

IDParent IDDepthSubject groupPopulationCountryCohortBiomarker Time definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianConverted unitAdjustment typeAdjusted onRegressed onExpressed asPublication

Reproducibility values

IDExcretion IDSubject groupPopulationCountryCohortBiomarker Time definitionBiospecimenAnalytical methodBiomarkerBiomarker detailArithmetic meanGeometric meanMedianUnitAdjusted onReproducibility sizeICCICC 95% CI lowerICC 95% CI upperCV% WSCV% BSVAR WSVAR BSPublication

Associations of biomarkers and exposures in KMCC (Korean Multi-center Cancer Cohort)

Correlation values

IDIntake IDExcretion IDSubject groupPopulationCountryCohortIntake Time definitionIntake Assessment methodIntakeIntake detailSupplement intakes included?Intake Arithmetic meanIntake Geometric meanIntake MedianIntake UnitIntake Adjusted onBiomarker Time definitionBiospecimenAnalytical methodBiomarkerBiomarker detailBiomarker Arithmetic meanBiomarker Geometric meanBiomarker MedianBiomarker UnitBiomarker Adjusted onCorrelation sizeCorrelation typeCorrelation valueCorrelation 95% CI lowerCorrelation 95% CI upperCorrelation p-valueSignificant?Measurement adjustmentDeattenuated?CovariatesPublication

Metabolomic associations

IDIntake IDExcretion IDSubject groupPopulationCountryCohortNo. of subjectsIntake Assessment methodIntakeIntervention doseBiospecimenAnalytical methodBiomarkerStructural identificationFeature selectionArea under curveSensitivitySpecificityPLS-DA VIPBeta coefficientBeta coefficient p-valueANOVA p-valuePublication

Associations of biomarkers and cancer risk in KMCC (Korean Multi-center Cancer Cohort)

Cancer associations

IDExcretion IDSubject groupPopulationCountryCohortNo. of subjectsNo. of casesNo. of controlsBiospecimenAnalytical methodBiomarkerBiomarker detailCancerStudy designPublication

Exposure data

Measurements of exposures in KMCC (Korean Multi-center Cancer Cohort)

Intake values

IDParent IDDepthSubject groupPopulationCountryCohortIntake Time definitionIntake assessment toolIntake food coverageIntake time coverageIntake Assessment methodIntakeIntake detailFood descriptionSupplement intakes included?Measurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianConverted unitAdjustment typeAdjusted onRegressed onExpressed asPublication