Vitamin B12

ID115
NameVitamin B12
Synonyms[Vitamin B12] / Cobalamin
StructureThumb
DescriptionIncludes all vitamers with vitamin B12 activity. Comprises 4 vitamers.
GroupTetrapyrroles
Sub-groupCobalamins
Exposure sourceDiet
UseVitamins
CAS number
PubChem ID
ChEBI ID
FooDB ID
HMDB ID

Biomarker measurements

Biomarker concentration values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed asPublication
7030AllPregnant women from a private obstetric hospital and a university hospitalJapanJPSerum, non-fastingChemiluminescence immunoassayVitamin B12167268.099.0pg/mL0.0 mg/LCrudeShiraishi 2012
11130AllElementary-school childrenJapanJPbaselineUrine, 24-hMicrobioassay (Lactobacillus leichmanii)Vitamin B121080.0260.015nmol/day0.0 umol/dayCrudeTsuji 2011
12390MalesParticipants in a dietary validation studyJapanJPJPHC StudyPlasma, fastingChemiluminescence immunoassayVitamin B1290479.3234.1pmol/L0.5 nmol/LCrudeKobayashi 2011
13160AllUniversity studentsJapanJPbaselineUrine, 24-hMicrobioassay (Lactobacillus leichmanii)Vitamin B121480.0280.018nmol/day0.0 umol/dayCrudeTsuji 2010
14030Males - Tertile 1 (Vitamin intake: unspecified)Participants in a dietary validation studySwedenSEVIP cohort (Vasterbotten Intervention Project)Plasma, fastingQuantaphase II radioassayVitamin B1232132.0pmol/L0.1 nmol/LCrudeJohansson 2010
14040Males - Tertile 2 (Vitamin intake: unspecified)Participants in a dietary validation studySwedenSEVIP cohort (Vasterbotten Intervention Project)Plasma, fastingQuantaphase II radioassayVitamin B1232170.0pmol/L0.2 nmol/LCrudeJohansson 2010
14050Males - Tertile 3 (Vitamin intake: unspecified)Participants in a dietary validation studySwedenSEVIP cohort (Vasterbotten Intervention Project)Plasma, fastingQuantaphase II radioassayVitamin B1232155.0pmol/L0.2 nmol/LCrudeJohansson 2010
14120Females - Tertile 1 (Vitamin intake: unspecified)Participants in a dietary validation studySwedenSEVIP cohort (Vasterbotten Intervention Project)Plasma, fastingQuantaphase II radioassayVitamin B1233144.0pmol/L0.1 nmol/LCrudeJohansson 2010
14130Females - Tertile 2 (Vitamin intake: unspecified)Participants in a dietary validation studySwedenSEVIP cohort (Vasterbotten Intervention Project)Plasma, fastingQuantaphase II radioassayVitamin B1233146.0pmol/L0.1 nmol/LCrudeJohansson 2010
14140Females - Tertile 3 (Vitamin intake: unspecified)Participants in a dietary validation studySwedenSEVIP cohort (Vasterbotten Intervention Project)Plasma, fastingQuantaphase II radioassayVitamin B1233173.0pmol/L0.2 nmol/LCrudeJohansson 2010
14810FFQ 1 - Quintile 1 (Vitamin intake: unspecified)Controls in a case-control study on B vitamins and prostate cancerSwedenSEVIP cohort (Vasterbotten Intervention Project)Plasma, fastingMicrobioassay (Lactobacillus leichmanii)Vitamin B12106312.0pmol/L0.3 nmol/LCrudeJohansson 2010
14820FFQ 1 - Quintile 2 (Vitamin intake: unspecified)Controls in a case-control study on B vitamins and prostate cancerSwedenSEVIP cohort (Vasterbotten Intervention Project)Plasma, fastingMicrobioassay (Lactobacillus leichmanii)Vitamin B12106363.0pmol/L0.4 nmol/LCrudeJohansson 2010
14830FFQ 1 - Quintile 3 (Vitamin intake: unspecified)Controls in a case-control study on B vitamins and prostate cancerSwedenSEVIP cohort (Vasterbotten Intervention Project)Plasma, fastingMicrobioassay (Lactobacillus leichmanii)Vitamin B12106346.0pmol/L0.3 nmol/LCrudeJohansson 2010
14840FFQ 1 - Quintile 4 (Vitamin intake: unspecified)Controls in a case-control study on B vitamins and prostate cancerSwedenSEVIP cohort (Vasterbotten Intervention Project)Plasma, fastingMicrobioassay (Lactobacillus leichmanii)Vitamin B12106315.0pmol/L0.3 nmol/LCrudeJohansson 2010
14850FFQ 1 - Quintile 5 (Vitamin intake: unspecified)Controls in a case-control study on B vitamins and prostate cancerSwedenSEVIP cohort (Vasterbotten Intervention Project)Plasma, fastingMicrobioassay (Lactobacillus leichmanii)Vitamin B12106380.0pmol/L0.4 nmol/LCrudeJohansson 2010
14910FFQ 2 - Quintile 1 (Vitamin intake: unspecified)Controls in a case-control study on B vitamins and prostate cancerSwedenSEVIP cohort (Vasterbotten Intervention Project)Plasma, fastingMicrobioassay (Lactobacillus leichmanii)Vitamin B1268318.0pmol/L0.3 nmol/LCrudeJohansson 2010
14920FFQ 2 - Quintile 2 (Vitamin intake: unspecified)Controls in a case-control study on B vitamins and prostate cancerSwedenSEVIP cohort (Vasterbotten Intervention Project)Plasma, fastingMicrobioassay (Lactobacillus leichmanii)Vitamin B1268321.0pmol/L0.3 nmol/LCrudeJohansson 2010
14930FFQ 2 - Quintile 3 (Vitamin intake: unspecified)Controls in a case-control study on B vitamins and prostate cancerSwedenSEVIP cohort (Vasterbotten Intervention Project)Plasma, fastingMicrobioassay (Lactobacillus leichmanii)Vitamin B1268358.0pmol/L0.4 nmol/LCrudeJohansson 2010
14940FFQ 2 - Quintile 4 (Vitamin intake: unspecified)Controls in a case-control study on B vitamins and prostate cancerSwedenSEVIP cohort (Vasterbotten Intervention Project)Plasma, fastingMicrobioassay (Lactobacillus leichmanii)Vitamin B1268363.0pmol/L0.4 nmol/LCrudeJohansson 2010
14950FFQ 2 - Quintile 5 (Vitamin intake: unspecified)Controls in a case-control study on B vitamins and prostate cancerSwedenSEVIP cohort (Vasterbotten Intervention Project)Plasma, fastingMicrobioassay (Lactobacillus leichmanii)Vitamin B1268356.0pmol/L0.4 nmol/LCrudeJohansson 2010
17810AllElderly womenJapanJPDay 4Urine, 24-hMicrobioassay (Lactobacillus leichmanii)Vitamin B12350.0340.035nmol/day0.0 umol/dayCrudeTsuji 2010
26490Supplement nonusersFemale students at the University of ManitobaCanadaCASerum, fastingQuantaphase II radioassayVitamin B1270398.5541.3661.6pg/mL0.0 mg/LCrudeShuaibi 2008
26510Supplement usersFemale students at the University of ManitobaCanadaCASerum, fastingQuantaphase II radioassayVitamin B1225545.9710.31056.3pg/mL0.0 mg/LCrudeShuaibi 2008
31180AllWomen of reproductive age participant in a case-control study on congenital heart defectsNetherlandsNLSerum, fastingChemiluminescence immunoassayVitamin B1253190.0245.0339.0pmol/L0.2 nmol/LCrudeVerkleij-Hagoort 2007
32030AllElderly participants in three folate supplementation studiesNetherlandsNLSerum, fastingChemiluminescence immunoassayVitamin B121281318.8168.4pmol/L0.3 nmol/LCrudevan de Rest 2007
32080FACIT-StudyElderly participants in three folate supplementation studiesNetherlandsNLFACIT (Folic Acid and Carotid Intima-media Thickness)Serum, fastingChemiluminescence immunoassayVitamin B12819320.3191.9pmol/L0.3 nmol/LCrudevan de Rest 2007
32130CHEF-StudyElderly participants in three folate supplementation studiesNetherlandsNLCHEFSerum, fastingChemiluminescence immunoassayVitamin B12157316.387.9pmol/L0.3 nmol/LCrudevan de Rest 2007
32180Dolfin-StudyElderly participants in three folate supplementation studiesNetherlandsNLDolfinSerum, fastingChemiluminescence immunoassayVitamin B12305316.0128.0pmol/L0.3 nmol/LCrudevan de Rest 2007
37370Quartile 1 (Adherence: <38.77%, MDI)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingRadioimmunoassayVitamin B1282610.79383.63pg/mL0.0 mg/LCrudeBach-Faig 2006
37380Quartile 1 (Adherence: <3.63%, MDS)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingRadioimmunoassayVitamin B1282661.62603.98pg/mL0.0 mg/LCrudeBach-Faig 2006
37530Quartile 2 (Adherence: 38.77 to 48%, MDI)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingRadioimmunoassayVitamin B1282556.48216.43pg/mL0.0 mg/LCrudeBach-Faig 2006
37540Quartile 2 (Adherence: 3.63 to 4.71%, MDS)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingRadioimmunoassayVitamin B1282608.16221.9pg/mL0.0 mg/LCrudeBach-Faig 2006
37690Quartile 3 (Adherence: 48 to 56.24%, MDI)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingRadioimmunoassayVitamin B1282773.3869.33pg/mL0.0 mg/LCrudeBach-Faig 2006
37700Quartile 3 (Adherence: 4.71 to 5.83%, MDS)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingRadioimmunoassayVitamin B1282710.93844.48pg/mL0.0 mg/LCrudeBach-Faig 2006
37850Quartile 4 (Adherence: >56.24%, MDI)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingRadioimmunoassayVitamin B1282622.91481.83pg/mL0.0 mg/LCrudeBach-Faig 2006
37860Quartile 4 (Adherence: >5.83%, MDS)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingRadioimmunoassayVitamin B1282572.61242.63pg/mL0.0 mg/LCrudeBach-Faig 2006
73640Supplement nonusersYoung women from Southern OntarioCanadaCASerum, fastingQuantaphase II radioassayVitamin B1281223.0281.0337.0pmol/L0.3 nmol/LCrudeGreen 1998
73670Supplement usersYoung women from Southern OntarioCanadaCASerum, fastingQuantaphase II radioassayVitamin B1222249.0349.0451.0pmol/L0.3 nmol/LCrudeGreen 1998
91500MalesParticipants in a case-control study of nutritional status and age-related cataractsUnited StatesUSPlasma, unspecifiedMissingVitamin B1254280.0151.0pmol/L0.3 nmol/LCrudeJacques 1993
91600Males - Supplement nonusersParticipants in a case-control study of nutritional status and age-related cataractsUnited StatesUSPlasma, unspecifiedMissingVitamin B1240244.0132.0pmol/L0.2 nmol/LCrudeJacques 1993
91700FemalesParticipants in a case-control study of nutritional status and age-related cataractsUnited StatesUSPlasma, unspecifiedMissingVitamin B1278294.0150.0pmol/L0.3 nmol/LCrudeJacques 1993
91800Females - Supplement nonusersParticipants in a case-control study of nutritional status and age-related cataractsUnited StatesUSPlasma, unspecifiedMissingVitamin B1265276.0137.0pmol/L0.3 nmol/LCrudeJacques 1993

Intake values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionIntake toolIntake food coverageIntake time coverageIntake assessmentCompoundCompound detailSupplement intakes included?Measurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed asPublication
7000AllPregnant women from a private obstetric hospital and a university hospitalJapanJPDiet History Questionnaire (DHQ)Vitamin B12No1675.743.1ug/day0.0 mg/dayCrudeShiraishi 2012
7010AllPregnant women from a private obstetric hospital and a university hospitalJapanJPDiet History Questionnaire (DHQ)Vitamin B12No1673.11.35ug/1000 kcal0.0 mg/1000 kcalDensityEnergyShiraishi 2012
11220AllElementary-school childrenJapanJPDay 4Weighed Dietary record (4-day)Vitamin B12No1083.151.97nmol/day0.0 umol/dayCrudeTsuji 2011
11310AllElementary-school childrenJapanJPDay 3Weighed Dietary record (4-day)Vitamin B12No1084.855.93nmol/day0.0 umol/dayCrudeTsuji 2011
11400AllElementary-school childrenJapanJPDay 2Weighed Dietary record (4-day)Vitamin B12No1084.764.29nmol/day0.0 umol/dayCrudeTsuji 2011
11490AllElementary-school childrenJapanJPDay 1Weighed Dietary record (4-day)Vitamin B12No1084.643.37nmol/day0.0 umol/dayCrudeTsuji 2011
11580AllElementary-school childrenJapanJPWeighed Dietary record (4-day)Vitamin B12No1084.352.1nmol/day0.0 umol/dayCrudeTsuji 2011
11840MalesParticipants in a dietary validation studyJapanJPJPHC StudybaselineCalculated with FDB_raw databaseDietary record (7-day)Vitamin B1210212.010.9ug/day0.0 mg/dayCrudeKobayashi 2011
12000MalesParticipants in a dietary validation studyJapanJPJPHC StudybaselineCalculated with FDB_cook databaseDietary record (7-day)Vitamin B1210212.112.2ug/day0.0 mg/dayCrudeKobayashi 2011
12150FemalesParticipants in a dietary validation studyJapanJPJPHC StudybaselineCalculated with FDB_raw databaseDietary record (7-day)Vitamin B1211310.28.5ug/day0.0 mg/dayCrudeKobayashi 2011
12300FemalesParticipants in a dietary validation studyJapanJPJPHC StudybaselineCalculated with FDB_cook databaseDietary record (7-day)Vitamin B1211310.811.8ug/day0.0 mg/dayCrudeKobayashi 2011
13270AllUniversity studentsJapanJPDay 4Weighed Dietary record (4-day)Vitamin B12No1482.883.42nmol/day0.0 umol/dayCrudeTsuji 2010
13360AllUniversity studentsJapanJPDay 3Weighed Dietary record (4-day)Vitamin B12No1483.593.86nmol/day0.0 umol/dayCrudeTsuji 2010
13450AllUniversity studentsJapanJPDay 2Weighed Dietary record (4-day)Vitamin B12No1483.495.16nmol/day0.0 umol/dayCrudeTsuji 2010
13540AllUniversity studentsJapanJPDay 1Weighed Dietary record (4-day)Vitamin B12No1483.055.69nmol/day0.0 umol/dayCrudeTsuji 2010
13630AllUniversity studentsJapanJPWeighed Dietary record (4-day)Vitamin B12No1483.232.84nmol/day0.0 umol/dayCrudeTsuji 2010
13970Males - Tertile 1 (Vitamin intake: unspecified)Participants in a dietary validation studySwedenSEVIP cohort (Vasterbotten Intervention Project)Northern Sweden FFQ84-item1 yearFood Frequency Questionnaire (FFQ)Vitamin B12No325.44ug/day0.0 mg/dayCrudeJohansson 2010
13980Males - Tertile 2 (Vitamin intake: unspecified)Participants in a dietary validation studySwedenSEVIP cohort (Vasterbotten Intervention Project)Northern Sweden FFQ84-item1 yearFood Frequency Questionnaire (FFQ)Vitamin B12No327.22ug/day0.0 mg/dayCrudeJohansson 2010
13990Males - Tertile 3 (Vitamin intake: unspecified)Participants in a dietary validation studySwedenSEVIP cohort (Vasterbotten Intervention Project)Northern Sweden FFQ84-item1 yearFood Frequency Questionnaire (FFQ)Vitamin B12No328.35ug/day0.0 mg/dayCrudeJohansson 2010
14000Males - Tertile 1 (Vitamin intake: unspecified)Participants in a dietary validation studySwedenSEVIP cohort (Vasterbotten Intervention Project)24-h Dietary recall (1-day)Vitamin B12No324.1ug/day0.0 mg/dayCrudeJohansson 2010
14010Males - Tertile 2 (Vitamin intake: unspecified)Participants in a dietary validation studySwedenSEVIP cohort (Vasterbotten Intervention Project)24-h Dietary recall (1-day)Vitamin B12No326.42ug/day0.0 mg/dayCrudeJohansson 2010
14020Males - Tertile 3 (Vitamin intake: unspecified)Participants in a dietary validation studySwedenSEVIP cohort (Vasterbotten Intervention Project)24-h Dietary recall (1-day)Vitamin B12No3210.48ug/day0.0 mg/dayCrudeJohansson 2010
14060Females - Tertile 1 (Vitamin intake: unspecified)Participants in a dietary validation studySwedenSEVIP cohort (Vasterbotten Intervention Project)Northern Sweden FFQ84-item1 yearFood Frequency Questionnaire (FFQ)Vitamin B12No334.27ug/day0.0 mg/dayCrudeJohansson 2010
14070Females - Tertile 2 (Vitamin intake: unspecified)Participants in a dietary validation studySwedenSEVIP cohort (Vasterbotten Intervention Project)Northern Sweden FFQ84-item1 yearFood Frequency Questionnaire (FFQ)Vitamin B12No334.97ug/day0.0 mg/dayCrudeJohansson 2010
14080Females - Tertile 3 (Vitamin intake: unspecified)Participants in a dietary validation studySwedenSEVIP cohort (Vasterbotten Intervention Project)Northern Sweden FFQ84-item1 yearFood Frequency Questionnaire (FFQ)Vitamin B12No335.01ug/day0.0 mg/dayCrudeJohansson 2010
14090Females - Tertile 1 (Vitamin intake: unspecified)Participants in a dietary validation studySwedenSEVIP cohort (Vasterbotten Intervention Project)24-h Dietary recall (1-day)Vitamin B12No333.04ug/day0.0 mg/dayCrudeJohansson 2010
14100Females - Tertile 2 (Vitamin intake: unspecified)Participants in a dietary validation studySwedenSEVIP cohort (Vasterbotten Intervention Project)24-h Dietary recall (1-day)Vitamin B12No334.6ug/day0.0 mg/dayCrudeJohansson 2010
14110Females - Tertile 3 (Vitamin intake: unspecified)Participants in a dietary validation studySwedenSEVIP cohort (Vasterbotten Intervention Project)24-h Dietary recall (1-day)Vitamin B12No337.44ug/day0.0 mg/dayCrudeJohansson 2010
14760FFQ 1 - Quintile 1 (Vitamin intake: unspecified)Controls in a case-control study on B vitamins and prostate cancerSwedenSEVIP cohort (Vasterbotten Intervention Project)Northern Sweden FFQ84-item1 yearFood Frequency Questionnaire (FFQ)Vitamin B12Yes1063.36ug/day0.0 mg/dayCrudeJohansson 2010
14770FFQ 1 - Quintile 2 (Vitamin intake: unspecified)Controls in a case-control study on B vitamins and prostate cancerSwedenSEVIP cohort (Vasterbotten Intervention Project)Northern Sweden FFQ84-item1 yearFood Frequency Questionnaire (FFQ)Vitamin B12Yes1064.86ug/day0.0 mg/dayCrudeJohansson 2010
14780FFQ 1 - Quintile 3 (Vitamin intake: unspecified)Controls in a case-control study on B vitamins and prostate cancerSwedenSEVIP cohort (Vasterbotten Intervention Project)Northern Sweden FFQ84-item1 yearFood Frequency Questionnaire (FFQ)Vitamin B12Yes1066.02ug/day0.0 mg/dayCrudeJohansson 2010
14790FFQ 1 - Quintile 4 (Vitamin intake: unspecified)Controls in a case-control study on B vitamins and prostate cancerSwedenSEVIP cohort (Vasterbotten Intervention Project)Northern Sweden FFQ84-item1 yearFood Frequency Questionnaire (FFQ)Vitamin B12Yes1067.34ug/day0.0 mg/dayCrudeJohansson 2010
14800FFQ 1 - Quintile 5 (Vitamin intake: unspecified)Controls in a case-control study on B vitamins and prostate cancerSwedenSEVIP cohort (Vasterbotten Intervention Project)Northern Sweden FFQ84-item1 yearFood Frequency Questionnaire (FFQ)Vitamin B12Yes1069.3ug/day0.0 mg/dayCrudeJohansson 2010
14860FFQ 2 - Quintile 1 (Vitamin intake: unspecified)Controls in a case-control study on B vitamins and prostate cancerSwedenSEVIP cohort (Vasterbotten Intervention Project)Northern Sweden FFQ64-item1 yearFood Frequency Questionnaire (FFQ)Vitamin B12Yes683.22ug/day0.0 mg/dayCrudeJohansson 2010
14870FFQ 2 - Quintile 2 (Vitamin intake: unspecified)Controls in a case-control study on B vitamins and prostate cancerSwedenSEVIP cohort (Vasterbotten Intervention Project)Northern Sweden FFQ64-item1 yearFood Frequency Questionnaire (FFQ)Vitamin B12Yes684.33ug/day0.0 mg/dayCrudeJohansson 2010
14880FFQ 2 - Quintile 3 (Vitamin intake: unspecified)Controls in a case-control study on B vitamins and prostate cancerSwedenSEVIP cohort (Vasterbotten Intervention Project)Northern Sweden FFQ64-item1 yearFood Frequency Questionnaire (FFQ)Vitamin B12Yes685.25ug/day0.0 mg/dayCrudeJohansson 2010
14890FFQ 2 - Quintile 4 (Vitamin intake: unspecified)Controls in a case-control study on B vitamins and prostate cancerSwedenSEVIP cohort (Vasterbotten Intervention Project)Northern Sweden FFQ64-item1 yearFood Frequency Questionnaire (FFQ)Vitamin B12Yes686.46ug/day0.0 mg/dayCrudeJohansson 2010
14900FFQ 2 - Quintile 5 (Vitamin intake: unspecified)Controls in a case-control study on B vitamins and prostate cancerSwedenSEVIP cohort (Vasterbotten Intervention Project)Northern Sweden FFQ64-item1 yearFood Frequency Questionnaire (FFQ)Vitamin B12Yes688.77ug/day0.0 mg/dayCrudeJohansson 2010
17900AllElderly womenJapanJPDay 4Standard Tables of Food Composition in JapanWeighed Dietary record (4-day)Vitamin B12No355.814.91nmol/day0.0 umol/dayCrudeTsuji 2010
17990AllElderly womenJapanJPDay 3Standard Tables of Food Composition in JapanWeighed Dietary record (4-day)Vitamin B12No355.895.31nmol/day0.0 umol/dayCrudeTsuji 2010
18080AllElderly womenJapanJPDay 2Standard Tables of Food Composition in JapanWeighed Dietary record (4-day)Vitamin B12No354.954.31nmol/day0.0 umol/dayCrudeTsuji 2010
18170AllElderly womenJapanJPDay 1Standard Tables of Food Composition in JapanWeighed Dietary record (4-day)Vitamin B12No356.758.43nmol/day0.0 umol/dayCrudeTsuji 2010
18260AllElderly womenJapanJPDay 4Standard Tables of Food Composition in JapanWeighed Dietary record (4-day)Vitamin B12No355.853.16nmol/day0.0 umol/dayCrudeTsuji 2010
26250All [by supplement]Female students at the University of ManitobaCanadaCAFood Choice Map (FCM)Vitamin B12Yes952.94.28.8ug/day0.0 mg/dayCrudeShuaibi 2008
26270Supplement nonusersFemale students at the University of ManitobaCanadaCAFood Choice Map (FCM)Vitamin B12No702.83.55.5ug/day0.0 mg/dayCrudeShuaibi 2008
26290Supplement usersFemale students at the University of ManitobaCanadaCAFood Choice Map (FCM)Vitamin B12Yes259.514.525.4ug/day0.0 mg/dayCrudeShuaibi 2008
26310All [by supplement]Female students at the University of ManitobaCanadaCADietary record (3-day)Vitamin B12Yes952.33.68.5ug/day0.0 mg/dayCrudeShuaibi 2008
26330Supplement nonusersFemale students at the University of ManitobaCanadaCADietary record (3-day)Vitamin B12No702.22.84.2ug/day0.0 mg/dayCrudeShuaibi 2008
26350Supplement usersFemale students at the University of ManitobaCanadaCADietary record (3-day)Vitamin B12Yes258.415.723.9ug/day0.0 mg/dayCrudeShuaibi 2008
26370All [by supplement]Female students at the University of ManitobaCanadaCAFood Choice Map (FCM)Vitamin B12Yes953.04.68.0ug/day0.0 mg/dayRegressionEnergyShuaibi 2008
26390Supplement nonusersFemale students at the University of ManitobaCanadaCAFood Choice Map (FCM)Vitamin B12No702.473.55.0ug/day0.0 mg/dayRegressionEnergyShuaibi 2008
26410Supplement usersFemale students at the University of ManitobaCanadaCAFood Choice Map (FCM)Vitamin B12Yes259.614.025.4ug/day0.0 mg/dayRegressionEnergyShuaibi 2008
26430All [by supplement]Female students at the University of ManitobaCanadaCADietary record (3-day)Vitamin B12Yes952.33.68.2ug/day0.0 mg/dayRegressionEnergyShuaibi 2008
26450Supplement nonusersFemale students at the University of ManitobaCanadaCADietary record (3-day)Vitamin B12No702.22.83.8ug/day0.0 mg/dayRegressionEnergyShuaibi 2008
26470Supplement usersFemale students at the University of ManitobaCanadaCADietary record (3-day)Vitamin B12Yes258.515.824.2ug/day0.0 mg/dayRegressionEnergyShuaibi 2008
31220AllWomen of reproductive age participant in a case-control study on congenital heart defectsNetherlandsNLFood Frequency Questionnaire (FFQ)Vitamin B12No532.73.94.7ug/day0.0 mg/dayCrudeVerkleij-Hagoort 2007
31250AllWomen of reproductive age participant in a case-control study on congenital heart defectsNetherlandsNL24-h Dietary recall (1-day)Vitamin B12No532.63.44.3ug/day0.0 mg/dayCrudeVerkleij-Hagoort 2007
35630MalesParticipants in a dietary validation studyDenmarkDKInter99Food Frequency Questionnaire (FFQ)Vitamin B121253.05.214.0ug/day0.0 mg/dayCrudeToft 2008
35750FemalesParticipants in a dietary validation studyDenmarkDKInter99Food Frequency Questionnaire (FFQ)Vitamin B121392.04.210.0ug/day0.0 mg/dayCrudeToft 2008
57700AllControls in a case-control study on diet and heart diseaseCosta RicaCR24-h Dietary recall (1-day)Vitamin B121203.63.6ug/day0.0 mg/dayCrudeKabagambe 2001
57960AllControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)Vitamin B121205.33.9ug/day0.0 mg/dayCrudeKabagambe 2001
58220AllControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)Vitamin B121204.63.2ug/day0.0 mg/dayCrudeKabagambe 2001
58480AllControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)Vitamin B121204.93.1ug/day0.0 mg/dayCrudeKabagambe 2001
73380Supplement nonusersYoung women from Southern OntarioCanadaCAFood Frequency Questionnaire (FFQ)Vitamin B12No813.44.47.0ug/day0.0 mg/dayCrudeGreen 1998
73400Supplement usersYoung women from Southern OntarioCanadaCAFood Frequency Questionnaire (FFQ)Vitamin B12Yes227.511.413.9ug/day0.0 mg/dayCrudeGreen 1998
73420All [by supplement]Young women from Southern OntarioCanadaCAFood Frequency Questionnaire (FFQ)Vitamin B12Yes1033.64.910.0ug/day0.0 mg/dayCrudeGreen 1998
73450Supplement nonusersYoung women from Southern OntarioCanadaCAWeighed Dietary record (3-day)Vitamin B12No810.71.72.4ug/day0.0 mg/dayCrudeGreen 1998
73470Supplement usersYoung women from Southern OntarioCanadaCAWeighed Dietary record (3-day)Vitamin B12Yes225.77.47.9ug/day0.0 mg/dayCrudeGreen 1998
73490All [by supplement]Young women from Southern OntarioCanadaCAWeighed Dietary record (3-day)Vitamin B12Yes1031.01.93.7ug/day0.0 mg/dayCrudeGreen 1998
73510Supplement nonusersYoung women from Southern OntarioCanadaCAFood Frequency Questionnaire (FFQ)Vitamin B12No811.62.33.5ug/1000 kcal0.0 mg/1000 kcalDensityEnergyGreen 1998
73530Supplement usersYoung women from Southern OntarioCanadaCAFood Frequency Questionnaire (FFQ)Vitamin B12Yes224.05.09.4ug/1000 kcal0.0 mg/1000 kcalDensityEnergyGreen 1998
73550All [by supplement]Young women from Southern OntarioCanadaCAFood Frequency Questionnaire (FFQ)Vitamin B12Yes1031.72.64.3ug/1000 kcal0.0 mg/1000 kcalDensityEnergyGreen 1998
73570Supplement nonusersYoung women from Southern OntarioCanadaCAWeighed Dietary record (3-day)Vitamin B12No810.40.81.3ug/1000 kcal0.0 mg/1000 kcalDensityEnergyGreen 1998
73590Supplement usersYoung women from Southern OntarioCanadaCAWeighed Dietary record (3-day)Vitamin B12Yes222.84.49.7ug/1000 kcal0.0 mg/1000 kcalDensityEnergyGreen 1998
73610All [by supplement]Young women from Southern OntarioCanadaCAWeighed Dietary record (3-day)Vitamin B12Yes1030.61.02.0ug/1000 kcal0.0 mg/1000 kcalDensityEnergyGreen 1998
90700MalesParticipants in a case-control study of nutritional status and age-related cataractsUnited StatesUSFood Frequency Questionnaire (FFQ)Vitamin B12Yes5715.820.4ug/day0.0 mg/dayCrudeJacques 1993
90800MalesParticipants in a case-control study of nutritional status and age-related cataractsUnited StatesUSFood Frequency Questionnaire (FFQ)Vitamin B12Yes575.25.9ug/1000 kcal0.0 mg/1000 kcalDensityEnergyJacques 1993
90900FemalesParticipants in a case-control study of nutritional status and age-related cataractsUnited StatesUSFood Frequency Questionnaire (FFQ)Vitamin B12Yes8211.913.3ug/day0.0 mg/dayCrudeJacques 1993
91000FemalesParticipants in a case-control study of nutritional status and age-related cataractsUnited StatesUSFood Frequency Questionnaire (FFQ)Vitamin B12Yes825.15.8ug/1000 kcal0.0 mg/1000 kcalDensityEnergyJacques 1993
91100Males - Supplement nonusersParticipants in a case-control study of nutritional status and age-related cataractsUnited StatesUSFood Frequency Questionnaire (FFQ)Vitamin B12No439.56.4ug/day0.0 mg/dayCrudeJacques 1993
91200Males - Supplement nonusersParticipants in a case-control study of nutritional status and age-related cataractsUnited StatesUSFood Frequency Questionnaire (FFQ)Vitamin B12No433.21.6ug/1000 kcal0.0 mg/1000 kcalDensityEnergyJacques 1993
91300Females - Supplement nonusersParticipants in a case-control study of nutritional status and age-related cataractsUnited StatesUSFood Frequency Questionnaire (FFQ)Vitamin B12No689.28.3ug/day0.0 mg/dayCrudeJacques 1993
91400Females - Supplement nonusersParticipants in a case-control study of nutritional status and age-related cataractsUnited StatesUSFood Frequency Questionnaire (FFQ)Vitamin B12No683.92.8ug/1000 kcal0.0 mg/1000 kcalDensityEnergyJacques 1993

Correlation values

Reproducibility values

IDMst. IDSubject groupPopulationCountryCountry codeCohortTime definitionBiological specimenExperimental methodBiomarkerBiomarker detailArithmetic meanGeometric meanMedianUnitAdjusted onReproducibility sizeICCICC 95% CI lowerICC 95% CI upperCV% WSCV% BSVAR WSVAR BSPublication
331766All [by diagnosis]Elderly subjects with and without mild cognitive impairmentUnited StatesUSbaseline; 1 monthPlasma, fastingRadioimmunoassayVitamin B12missing unit380.97Bowman 2011
571744No cognitive impairmentElderly subjects with and without mild cognitive impairmentUnited StatesUSbaseline; 1 monthPlasma, fastingRadioimmunoassayVitamin B12missing unit190.97Bowman 2011
791722Mild cognitive impairmentElderly subjects with and without mild cognitive impairmentUnited StatesUSbaseline; 1 monthPlasma, fastingRadioimmunoassayVitamin B12missing unit190.94Bowman 2011
61319084AllDutch participants of the EPIC-StudyNetherlandsNLMORGEN-EPIC projectbaseline; 3 yearsSerum, non-fastingChemiluminescence immunoassayVitamin B12nmol/L620.760.660.84Leenders 2013
66119118MalesCollege students consuming a semi-purified diet with water-soluble vitaminsJapanJPbaseline; 1 day; 2 days; 3 days; 4 days; 5 days; 6 daysUrine, 24-hMicrobioassay (Lactobacillus leichmanii)Vitamin B12mmol/L1023.851.1Shibata 2009
67019127MalesCollege students consuming a semi-purified diet with water-soluble vitaminsJapanJPbaseline; 2 day; 4 days; 7 daysWhole blood, fastingChemiluminescence immunoassayVitamin B12mmol/L103.822.5Shibata 2009
67919136FemalesCollege students consuming a semi-purified diet with water-soluble vitaminsJapanJPbaseline; 1 day; 2 days; 3 days; 4 days; 5 days; 6 daysUrine, 24-hMicrobioassay (Lactobacillus leichmanii)Vitamin B12mmol/L1024.046.4Shibata 2009
68819145FemalesCollege students consuming a semi-purified diet with water-soluble vitaminsJapanJPbaseline; 2 day; 7 daysWhole blood, fastingChemiluminescence immunoassayVitamin B12mmol/L1034.427.3Shibata 2009