ID1209
NameBDE-183
Synonyms2,2',3,4,4',5',6-Heptabromodiphenyl ether
StructureThumb
Description
ClassificationCompounds > Pollution > Air and water pollutants > Polybrominated diphenyl ethers (PBDE)
CAS number207122-16-5
PubChem ID15509899
ChEBI ID
FooDB IDFDB016628
HMDB IDHMDB37546

Chemical data

MolDBi data

IUPAC Name1,2,3,5-tetrabromo-4-(2,4,5-tribromophenoxy)benzene
Traditional IUPAC Name1,2,3,5-tetrabromo-4-(2,4,5-tribromophenoxy)benzene
FormulaC12H3Br7O
InChIInChI=1S/C12H3Br7O/c13-4-1-6(15)9(3-5(4)14)20-12-8(17)2-7(16)10(18)11(12)19/h1-3H
InChI KeyILPSCQCLBHQUEM-UHFFFAOYSA-N
Molecular weight722.48
Exact mass715.446753247
SMILESBrC1=CC(Br)=C(OC2=CC(Br)=C(Br)C=C2Br)C(Br)=C1Br

ClassyFire Taxonomy

Description belongs to the class of organic compounds known as bromodiphenyl ethers. Bromodiphenyl ethers are compounds that contain two benzene groups linked to each other via an ether bond, and where at least one ring is substituted with a bromo group.
KingdomOrganic compounds
Super ClassBenzenoids
ClassBenzene and substituted derivatives
Sub ClassDiphenylethers
Direct ParentBromodiphenyl ethers
Alternative Parents

Publications with BDE-183

TitleFirst authorYear
Distribution of PCDD/Fs, PCBs, PBDEs and organochlorine residues in children’s blood from Zhejiang, ChinaShen2010
Assessment of current serum levels of PCDD/Fs, dl-PCBs and PBDEs in a Dutch cohort with known perinatal PCDD/F exposureLeijs2008
Concentrations of polybrominated diphenyl ethers, polychlorinated dibenzo-p-dioxins and dibenzofurans, and polychlorinated biphenyls in human blood samples from KoreaKim2005
Inverse age-dependent accumulation of decabromodiphenyl ether and other PBDEs in serum from a general adult populationGari2013
Serum PBDEs in a North Carolina toddler cohort: associations with handwipes, house dust, and socioeconomic variablesStapleton2012
Assessment of polybrominated diphenyl ethers (PBDEs) in serum from the Korean general populationKim2012
Polybrominated diphenyl ethers (PBDE) in blood of children in Baden-Württemberg between 2002/03 and 2008/09Link2012
Levels of tetrabromobisphenol A, hexabromocyclododecanes and polybrominated diphenyl ethers in human milk from the general population in Beijing, ChinaShi2013
Polybrominated diphenyl ethers exposure in breast milk in Shanghai, China: levels, influencing factors and potential health risk for infantsCui2012
Levels and congener profiles of polybrominated diphenyl ethers (PBDEs) in breast milk from Shanghai: implication for exposure route of higher brominated BDEsMa2012
Cord blood levels of thyroid hormones and IGF-1 weakly correlate with breast milk levels of PBDEs in TaiwanShy2012
Brominated flame retardants in serum from the general population in northern ChinaZhu2009
Concentrations of polybrominated diphenyl ethers in blood serum from New ZealandHarrad2007
Polybrominated diphenyl ethers in blood from Korean incinerator workers and general populationLee2007
Human maternal and umbilical cord blood concentrations of polybrominated diphenyl ethersFoster2011
Negative associations between PBDE levels and thyroid hormones in cord bloodLin2011
Distribution of polybrominated diphenyl ethers (PBDEs) and other persistent organic pollutants in human serum from GreeceKalantzi2011
Polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) in breast milk from the Pacific NorthwestShe2007
Partitioning of polybrominated diphenyl ethers (PBDEs) in serum and milk from the same mothersSchecter2010
Relationships between polybrominated diphenyl ether concentrations in house dust and serumJohnson2010
Significantly higher polybrominated diphenyl ether levels in young U.S. children than in their mothersLunder2010
Prenatal exposure to PBDEs and neurodevelopmentHerbstman2010
Congener-specific body burden levels and possible determinants of polybrominated diphenyl ethers in the general Japanese populationUemura2010
Concentrations of polybrominated diphenyl ethers in breast milk correlated to maternal age, education level, and occupational exposureChao2010
Levels and patterns of polybrominated diphenyl ethers in children's plasma from Dalian, ChinaChen2010
Breast-milk levels of polybrominated diphenyl ether flame retardants in relation to women's age and pre-pregnant body mass indexKoh2010
Determinants of serum polybrominated diphenyl ether (PBDE) levels among pregnant women in the CHAMACOS cohortCastorina2011
Prenatal exposure to polybrominated diphenyl ether flame retardants and neonatal thyroid-stimulating hormone levels in the CHAMACOS studyChevrier2011
Factors associated with serum polybrominated diphenyl ether (PBDE) levels among school-age children in the CHAMACOS cohortBradman2012
Determinants of prenatal exposure to polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) in an urban populationHerbstman2007
Serum levels of polybrominated diphenyl ethers (PBDEs) in foam recyclers and carpet installers working in the United StatesStapleton2008
Distribution of polybrominated diphenyl ethers in human umbilical cord serum, paternal serum, maternal serum, placentas, and breast milk from Madrid population, SpainGomara2007
Polybrominated diphenyl ether levels in the blood of pregnant women living in an agricultural community in CaliforniaBradman2007
Polybrominated diphenyl ethers in South China maternal and fetal blood and breast milkBi2006
Comparisons of polybrominated diphenyl ethers levels in paired South Korean cord blood, maternal blood, and breast milk samplesKim2012
Concentrations and speciation of polybrominated diphenyl ethers in human amniotic fluidMiller2012
Neurodevelopment of infants with prenatal exposure to polybrominated diphenyl ethersShy2011
Polybrominated diphenyl ethers and synthetic musks in umbilical cord Serum, maternal serum, and breast milk from Seoul, South KoreaKang2010
Polybrominated diphenyl ethers in the serum and breast milk of the resident population from production area, ChinaJin2009
Exposure assessment of French women and their newborn to brominated flame retardants: determination of tri- to deca- polybromodiphenylethers (PBDE) in maternal adipose tissue, serum, breast milk and cord serumAntignac2009

Biomarker data

Measurements of BDE-183 in biospecimens

Concentration values

IDParent IDDepthSubject groupPopulationCountryCohortBiomarker Time definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianConverted unitAdjustment typeAdjusted onRegressed onExpressed asPublication

Reproducibility values

IDExcretion IDSubject groupPopulationCountryCohortBiomarker Time definitionBiospecimenAnalytical methodBiomarkerBiomarker detailArithmetic meanGeometric meanMedianUnitAdjusted onReproducibility sizeICCICC 95% CI lowerICC 95% CI upperCV% WSCV% BSVAR WSVAR BSPublication

Associations of BDE-183 with exposures

Correlation values

IDIntake IDExcretion IDSubject groupPopulationCountryCohortIntake Time definitionIntake Assessment methodIntakeIntake detailSupplement intakes included?Intake Arithmetic meanIntake Geometric meanIntake MedianIntake UnitIntake Adjusted onBiomarker Time definitionBiospecimenAnalytical methodBiomarkerBiomarker detailBiomarker Arithmetic meanBiomarker Geometric meanBiomarker MedianBiomarker UnitBiomarker Adjusted onCorrelation sizeCorrelation typeCorrelation valueCorrelation 95% CI lowerCorrelation 95% CI upperCorrelation p-valueSignificant?Measurement adjustmentDeattenuated?CovariatesPublication

Metabolomic associations

IDIntake IDExcretion IDSubject groupPopulationCountryCohortNo. of subjectsIntake Assessment methodIntakeIntervention doseBiospecimenAnalytical methodBiomarkerStructural identificationFeature selectionArea under curveSensitivitySpecificityPLS-DA VIPBeta coefficientBeta coefficient p-valueANOVA p-valuePublication

Associations of BDE-183 with cancer risk

Cancer associations

IDExcretion IDSubject groupPopulationCountryCohortNo. of subjectsNo. of casesNo. of controlsBiospecimenAnalytical methodBiomarkerBiomarker detailCancerStudy designPublication

Exposure data

Measurements of BDE-183 exposures in populations

Intake values

IDParent IDDepthSubject groupPopulationCountryCohortIntake Time definitionIntake assessment toolIntake food coverageIntake time coverageIntake Assessment methodIntakeIntake detailFood descriptionSupplement intakes included?Measurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianConverted unitAdjustment typeAdjusted onRegressed onExpressed asPublication

Associations of BDE-183 exposures with biomarkers

Correlation values

IDIntake IDExcretion IDSubject groupPopulationCountryCohortIntake Time definitionIntake Assessment methodIntakeIntake detailSupplement intakes included?Intake Arithmetic meanIntake Geometric meanIntake MedianIntake UnitIntake Adjusted onBiomarker Time definitionBiospecimenAnalytical methodBiomarkerBiomarker detailBiomarker Arithmetic meanBiomarker Geometric meanBiomarker MedianBiomarker UnitBiomarker Adjusted onCorrelation sizeCorrelation typeCorrelation valueCorrelation 95% CI lowerCorrelation 95% CI upperCorrelation p-valueSignificant?Measurement adjustmentDeattenuated?CovariatesPublication