Vitamin C (Compound)

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ID134
NameVitamin C
SynonymsVitamin C
StructureThumb
DescriptionIncludes all vitamers with vitamin C activity: they are principally ascorbic acid and dehydroascorbic acid.
ClassificationCompounds > Diet > Vitamins > Vitamin C (Ascorbic acid)
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Publications with Vitamin C

TitleFirst authorYear
Validity and reproducibility of a food frequency questionnaire for assessment of fruit and vegetable intake in Iranian adultsMohammadifard2011
Twenty-four hour urinary water-soluble vitamin levels correlate with their intakes in free-living Japanese schoolchildrenTsuji2011
Effect of cooking loss in the assessment of vitamin intake for epidemiological data in JapanKobayashi2011
Twenty-four-hour urinary water-soluble vitamin levels correlate with their intakes in free-living Japanese university studentsTsuji2010
Reliability and validity of food frequency questionnaire and nutrient biomarkers in elders with and without mild cognitive impairmentBowman2011
Urinary excretion of vitamin B1, B2, B6, niacin, pantothenic acid, folate, and vitamin C correlates with dietary intakes of free-living elderly, female JapaneseTsuji2010
Validation of an antioxidant nutrient questionnaire in Whites and African AmericansSatia2009
Plasma concentrations of carotenoids and vitamin C are better correlated with dietary intake in normal weight than overweight and obese elderly subjectsVioque2007
Relationships between different types of fruit and vegetable consumption and serum concentrations of antioxidant vitaminsDauchet2008
Relative validity of a food frequency questionnaire used in the Inter99 studyToft2008
Evaluating associations between Mediterranean diet adherence indexes and biomarkers of diet and diseaseBach-Faig2006
Validity and reliability of a new food frequency questionnaire compared to 24 h recalls and biochemical measurements: pilot phase of Golestan cohort study of esophageal cancerMalekshah2006
Reproducibility, validity, and responsiveness to change of a short questionnaire for measuring fruit and vegetable intakeBogers2004
Reasonable estimates of serum vitamin E, vitamin C, and beta-cryptoxanthin are obtained with a food frequency questionnaire in older black and white adultsTangney2004
Application of the method of triads to evaluate the performance of food frequency questionnaires and biomarkers as indicators of long-term dietary intakeKabagambe2001
Which plasma antioxidants are most related to fruit and vegetable consumption?Block2001
Comparing biological measurements of vitamin C, folate, alpha-tocopherol and carotene with 24-hour dietary recall information in nonhispanic blacks and whitesKnutsen2001
Dietary assessment in Whitehall II: comparison of 7 d diet diary and food-frequency questionnaire and validity against biomarkersBrunner2001
Use of biological markers to validate self-reported dietary intake in a random sample of the European Prospective Investigation into Cancer United Kingdom Norfolk cohortMcKeown2001
Questionnaire assessment of antioxidants and retinol intakes in Mexican womenRomieu1999
Validation of a food frequency questionnaire for use in a Scottish population: correlation of antioxidant vitamin intakes with biochemical measuresBodner1998
Serum beta-carotene and vitamin C as biomarkers of vegetable and fruit intakes in a community-based sample of French adultsDrewnowski1997
Relative validity and reproducibility of a diet history questionnaire in Spain. III. Biochemical markersGonzalez1997
The Dutch EPIC food frequency questionnaire. II. Relative validity and reproducibility for nutrientsOcke1997
Reproducibility and relative validity of an extensive semi-quantitative food frequency questionnaire using dietary records and biochemical markers among Greek schoolteachersKatsouyanni1997
Biochemical validation of a self-administered semi-quantitative food-frequency questionnairePorrini1995
The accuracy of parental reports of their children's intake of fruits and vegetables: validation of a food frequency questionnaire with serum levels of carotenoids and vitamins C, A, and EByers1993
Comparison of micronutrient intake measured by a dietary questionnaire and biochemical indicators of micronutrient statusJacques1993
Determinants of plasma ascorbic acid in a healthy male populationSinha1992
Antioxidant vitamin intakes assessed using a food-frequency questionnaire: correlation with biochemical status in smokers and non-smokersBolton-Smith1991
Reliability of selected antioxidants and compounds involved in one-carbon metabolism in two Dutch cohortsLeenders2013
Plasma carotenoids, vitamin C, tocopherols, and retinol and the risk of breast cancer in the European Prospective Investigation into Cancer and Nutrition cohortBakker2016
Plasma carotenoids, vitamin C, retinol and tocopherols levels and pancreatic cancer risk within the European Prospective Investigation into Cancer and Nutrition: a nested case-control study: plasma micronutrients and pancreatic cancer riskJeurnink2015
Prediagnostic levels of serum micronutrients in relation to risk of gastric cancer in Shanghai, ChinaYuan2004
Plasma carotenoids and vitamin C concentrations and risk of urothelial cell carcinoma in the European Prospective Investigation into Cancer and NutritionRos2012
Plasma and dietary carotenoids and vitamins A, C and E and risk of colon and rectal cancer in the European Prospective Investigation into Cancer and NutritionLeenders2014
Dietary antioxidants and the aetiology of pancreatic cancer: a cohort study using data from food diaries and biomarkersBanim2013
Prediagnostic plasma vitamin C levels and the subsequent risk of prostate cancerBerndt2005
Plasma and dietary vitamin C levels and risk of gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST)Jenab2006
A prospective study of plasma ascorbic acid concentrations and breast cancer (United States)Wu2000
Dietary antioxidant intake and the risk of developing Barrett's oesophagus and oesophageal adenocarcinomaKang2018

Biomarker data

Measurements of Vitamin C in biospecimens

Concentration values

IDParent IDDepthSubject groupPopulationCountryCohortBiomarker Time definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianConverted unitAdjustment typeAdjusted onRegressed onExpressed asPublication

Reproducibility values

IDExcretion IDSubject groupPopulationCountryCohortBiomarker Time definitionBiospecimenAnalytical methodBiomarkerBiomarker detailArithmetic meanGeometric meanMedianUnitAdjusted onReproducibility sizeICCICC 95% CI lowerICC 95% CI upperCV% WSCV% BSVAR WSVAR BSPublication

Associations of Vitamin C with exposures

Correlation values

IDIntake IDExcretion IDSubject groupPopulationCountryCohortIntake Time definitionIntake Assessment methodIntakeIntake detailSupplement intakes included?Intake Arithmetic meanIntake Geometric meanIntake MedianIntake UnitIntake Adjusted onBiomarker Time definitionBiospecimenAnalytical methodBiomarkerBiomarker detailBiomarker Arithmetic meanBiomarker Geometric meanBiomarker MedianBiomarker UnitBiomarker Adjusted onCorrelation sizeCorrelation typeCorrelation valueCorrelation 95% CI lowerCorrelation 95% CI upperCorrelation p-valueSignificant?Measurement adjustmentDeattenuated?CovariatesPublication

Metabolomic associations

IDIntake IDExcretion IDSubject groupPopulationCountryCohortNo. of subjectsIntake Assessment methodIntakeIntervention doseBiospecimenAnalytical methodBiomarkerStructural identificationFeature selectionArea under curveSensitivitySpecificityPLS-DA VIPBeta coefficientBeta coefficient p-valueANOVA p-valuePublication

Associations of Vitamin C with cancer risk

Cancer associations

IDExcretion IDSubject groupPopulationCountryCohortNo. of subjectsNo. of casesNo. of controlsBiospecimenAnalytical methodBiomarkerBiomarker detailCancerStudy designPublication

Exposure data

Measurements of Vitamin C exposures in populations

Intake values

IDParent IDDepthSubject groupPopulationCountryCohortIntake Time definitionIntake assessment toolIntake food coverageIntake time coverageIntake Assessment methodIntakeIntake detailFood descriptionSupplement intakes included?Measurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianConverted unitAdjustment typeAdjusted onRegressed onExpressed asPublication

Associations of Vitamin C exposures with biomarkers

Correlation values

IDIntake IDExcretion IDSubject groupPopulationCountryCohortIntake Time definitionIntake Assessment methodIntakeIntake detailSupplement intakes included?Intake Arithmetic meanIntake Geometric meanIntake MedianIntake UnitIntake Adjusted onBiomarker Time definitionBiospecimenAnalytical methodBiomarkerBiomarker detailBiomarker Arithmetic meanBiomarker Geometric meanBiomarker MedianBiomarker UnitBiomarker Adjusted onCorrelation sizeCorrelation typeCorrelation valueCorrelation 95% CI lowerCorrelation 95% CI upperCorrelation p-valueSignificant?Measurement adjustmentDeattenuated?CovariatesPublication