Exposome-Explorer: show components

2,4-Dichlorophenol (2,4-DCP)

ID	1350
Name	2,4-Dichlorophenol (2,4-DCP)
Synonyms
Structure	MOL SDF 3D-SDF PDB SMILES InChI View 3D Structure Structure for #<Compound:0xa9daded8>
Description	Metabolite of 2,4-D. Used in the synthesis of phenoxy herbicides including 2,4-D.
Group	Organohalogens
Sub-group	Chlorophenols
Exposure source	Pesticides
Use	Herbicides
CAS number	120-83-2
PubChem ID	8449
ChEBI ID	16738
FooDB ID	FDB023422
HMDB ID	HMDB04811

Biomarker measurements

Biomarkers
Biospecimens
Analytical methods
Cohorts
Publications

Title	First author	Year
German Environmental Survey 1998 (GerES III): environmental pollutants in the urine of the German population	Becker	2003
Prenatal exposure to environmental phenols: concentrations in amniotic fluid and variability in urinary concentrations during pregnancy	Philippat	2013
Distribution, variability, and predictors of urinary concentrations of phenols and parabens among pregnant women in Puerto Rico	Meeker	2013
Temporal variability in urinary concentrations of phthalate metabolites, phytoestrogens and phenols among minority children in the United States	Teitelbaum	2008
Temporal variability in urinary excretion of bisphenol A and seven other phenols in spot, morning, and 24-h urine samples	Lassen	2013

Analytical method
GC-MS
LC-ID-MS/MS after enzymatic hydrolysis
LC-MS/MS after enzymatic hydrolysis

Biospecimen
Urine, first morning spot
Urine, spot
Urine, 24-h

Cohort
GerES III (German Environmental Survey 1998)
SARAEH (Advanced Reproductive Age and Environmental Health)
PROTECT (Puerto Rico Testsite for Exploring Contamination Threats)

Biomarker

Biomarker concentration values

ID	Parent ID	Depth	Subject group	Population	Country	Country code	Cohort	Time definition	Biospecimen	Analytical method	Biomarker	Biomarker detail	Measurement size	Detected (nb)	Detected (%)	Detected only?	Arithmethic mean	Arithmethic SD	Geometric mean	Geometric SD	Min	Min (detected)	Percentile_05	Percentile_10	Percentile_25	Median	Percentile_75	Percentile_90	Percentile_95	Max	Interquartile range	Mean 95% CI lower	Mean 95% CI upper	GMean 95% CI lower	GMean 95% CI upper	Unit	Converted arithmetic mean	Converted geometric mean	Converted median	Adjustment type	Adjusted on	Regressed on	Expressed as	Publication
16573		0	All [by smoking status]	General population	Germany	DE	GerES III (German Environmental Survey 1998)		Urine, first morning spot	GC-MS	2,4-Dichlorophenol (2,4-DCP)		692				1.43		0.43					0.1		0.4		1.6	2.7	168.0				0.4	0.47	ug/g	1.4 ug/g	0.4 ug/g	0.4 ug/g	Density	Creatinine			Becker 2003
18343		0	All	Pregnant women	United States	US	SARAEH (Advanced Reproductive Age and Environmental Health)	baseline	Urine, spot	LC-ID-MS/MS after enzymatic hydrolysis	2,4-Dichlorophenol (2,4-DCP)		71		68.0								0.0			0.6			5.7							ug/L			0.0 mg/L	Crude				Philippat 2013
18392		0	All	Pregnant women	Puerto Rico	PR	PROTECT (Puerto Rico Testsite for Exploring Contamination Threats)	baseline; 4 weeks; 8 weeks	Urine, spot	LC-ID-MS/MS after enzymatic hydrolysis	2,4-Dichlorophenol (2,4-DCP)		105		97.9				1.5						0.6	1.3	3.3		16.3	83.3				1.3	1.8	ng/mL		0.0 mg/L	0.0 mg/L	Crude				Meeker 2013
18704		0	All	Minority children	United States	US		baseline; 2 weeks; 1 month; 2 months, 3 months; 6 months	Urine, spot	LC-MS/MS after enzymatic hydrolysis	2,4-Dichlorophenol (2,4-DCP)		35						2.7		0.2					2.2			29.3	94.7						ug/g		2.7 ug/g	2.2 ug/g	Density	Creatinine			Teitelbaum 2008

Intake values

No data available

Correlation values

No data available

Reproducibility values

ID	Mst. ID	Subject group	Population	Country	Country code	Cohort	Time definition	Biological specimen	Experimental method	Biomarker	Biomarker detail	Arithmetic mean	Geometric mean	Median	Unit	Adjusted on	Reproducibility size	ICC	ICC 95% CI lower	ICC 95% CI upper	CV% WS	CV% BS	VAR WS	VAR BS	Publication
139	18352	All	Pregnant women	United States	US	SARAEH (Advanced Reproductive Age and Environmental Health)	baseline; 5 weeks; 15 weeks	Urine, spot	LC-ID-MS/MS after enzymatic hydrolysis	2,4-Dichlorophenol (2,4-DCP)					ug/L		71	0.47							Philippat 2013
148	18363	All	Pregnant women	United States	US	SARAEH (Advanced Reproductive Age and Environmental Health)	baseline; 5 weeks; 15 weeks	Urine, spot	LC-ID-MS/MS after enzymatic hydrolysis	2,4-Dichlorophenol (2,4-DCP)					ug/L	Creatinine	60	0.48							Philippat 2013
163	18392	All	Pregnant women	Puerto Rico	PR	PROTECT (Puerto Rico Testsite for Exploring Contamination Threats)	baseline; 4 weeks; 8 weeks	Urine, spot	LC-ID-MS/MS after enzymatic hydrolysis	2,4-Dichlorophenol (2,4-DCP)			1.5	1.3	ng/mL		105	0.37	0.25	0.5					Meeker 2013
359	18704	All	Minority children	United States	US		baseline; 2 weeks; 1 month; 2 months, 3 months; 6 months	Urine, spot	LC-MS/MS after enzymatic hydrolysis	2,4-Dichlorophenol (2,4-DCP)			2.7	2.2	ug/g	Creatinine	35	0.36					0.98	0.55	Teitelbaum 2008