Monoethyl phthalate (MEP)

ID1396
NameMonoethyl phthalate (MEP)
SynonymsMono-ethyl phthalate
StructureThumb
DescriptionMetabolite of diethyl phthalate (DEP).
GroupPhthalates
Sub-groupPhthalate monoesters
Exposure sourcePollution
UsePlasticizers
CAS number2306-33-4
PubChem ID75318
ChEBI ID70973
FooDB IDFDB022852
HMDB IDHMDB02120

Biomarker measurements

Biomarker concentration values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed asPublication
182320AllHmong womenUnited StatesUSFox River Environment and Diet Study cohort in Green Bay, Wisconsinbaseline; 15 days; 29.5 daysUrine, first morning spotLC-ID-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)45100.059.62.713.329.762.3103.4355.73866.6ug/g59.6 ug/g62.3 ug/gDensityCreatininePeck 2010
186720AllWomen in Washington DCUnited StatesUSA study to screen for uterine fibroids in 1996-1997baseline; 1 dayUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)35183.0135.332.1134.8611.1ug/g183.0 ug/g134.8 ug/gDensityCreatinineHoppin 2002
186840AllMinority childrenUnited StatesUSbaseline; 2 weeks; 1 month; 2 months, 3 months; 6 monthsUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)35176.415.3149.51378.66410.4ug/g176.4 ug/g149.5 ug/gDensityCreatinineTeitelbaum 2008
187300AllParticipants in a study of reproductive healthDenmarkDKbaseline; 40 days; 83 daysUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)33100.04.9913.320.153.1100.0939.019953.0ng/mL0.1 mg/LCrudeFrederiksen 2013
187460AllParticipants in a study of reproductive healthDenmarkDKbaseline; 4 daysUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)33100.02.977.5729.770.4354.02030.03321.0ng/mL0.1 mg/LCrudeFrederiksen 2013
187600AllParticipants in a study of reproductive healthDenmarkDKbaseline; 40 days; 83 daysUrine, 24-hLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)33100.08.4412.322.238.6104.01174.02635.0ng/mL0.0 mg/LCrudeFrederiksen 2013
188120AllPregnant women living in the Northern karst area of Puerto RicoPuerto RicoPRPROTECT (Puerto Rico Testsite for Exploring Contamination Threats)baseline; 4 weeks; 8 weeksUrine, spotLC-ID-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)139100.0102.224.799.2388.01880.012700.085.4122.2ng/mL0.1 mg/L0.1 mg/LCrudeCantonwine 2014
188950AllWomen seeking evaluation and treatment for infertility at the Massachusetts General HospitalUnited StatesUSEARTH (Environment and Reproductive Health)baseline; 12 weeksUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)13737.061.0145.0ug/L0.1 mg/LDensitySpecific gravityBraun 2012
189030AllWomen seeking evaluation and treatment for infertility at the Massachusetts General HospitalUnited StatesUSEARTH (Environment and Reproductive Health)baseline; 15 weeks; 28 weeksUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)13724.055.0116.0ug/L0.1 mg/LDensitySpecific gravityBraun 2012
189050AllSubjects in the metropolitan Atlanta area non-occupationally exposed to phthalatesUnited StatesUSbaseline; 1 day; 2 days; 3 days; 4 days; 5 days; 6 daysUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)8105.032.075.0280.0ug/g105.0 ug/g75.0 ug/gDensityCreatininePreau 2010
189070AllSubjects in the metropolitan Atlanta area non-occupationally exposed to phthalatesUnited StatesUSbaseline; 1 day; 2 days; 3 days; 4 days; 5 days; 6 daysUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)886.730.345.0161.0ug/g86.7 ug/g45.0 ug/gDensityCreatininePreau 2010
189090AllSubjects in the metropolitan Atlanta area non-occupationally exposed to phthalatesUnited StatesUSbaseline; 1 day; 2 days; 3 days; 4 days; 5 days; 6 daysUrine, 24-hLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)8136.041.097.1409.0ug/g136.0 ug/g97.1 ug/gDensityCreatininePreau 2010
18913205041AllWomenUnited StatesUSNHS (Nurses' Health Study)baseline; 2 yearsUrine, first morning spotLC-ID-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)40135.921.0140.5894.6ng/mg135.9 ug/g140.5 ug/gDensityCreatinineTownsend 2013
192560AllChildren with and without asthma and/or allergiesDenmarkDKIECH (Danish Indoor Environment and Children’s Health)Urine, first morning spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)44197.032.163.016.43.22.58.916.633.1104.7ng/mL0.0 mg/L0.0 mg/L0.0 mg/LCrudeLanger 2013
194160AllAdultsUnited StatesUSNHANES IIIUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)289345.030.2133.0288.0704.02610.06790.0ug/g345.0 ug/g288.0 ug/gDensityCreatinineBlount 2000
194290MalesEldersSwedenSEPIVUSSerum, fastingLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)5025013.087.2111.616.881.0ng/mL0.0 mg/LCrudeOlsen 2012
194400FemalesEldersSwedenSEPIVUSSerum, fastingLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)5015012.917.211.618.5191.0ng/mL0.0 mg/LCrudeOlsen 2012
194450ChildrenMother-child pairs in rural and urban DenmarkDenmarkDKUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)14528.05.57.913.019.029.093.0233.0ug/g28.0 ug/g19.0 ug/gDensityCreatinineFrederiksen 2013
194620MothersMother-child pairs in rural and urban DenmarkDenmarkDKUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)14564.05.58.316.029.071.0298.0581.0ug/g64.0 ug/g29.0 ug/gDensityCreatinineFrederiksen 2013
194860FemalesSubjects living in Central ItalyItalyITUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)8398.072.94355.916.8465.8948.863.63149.51ug/g72.9 ug/g65.8 ug/gDensityCreatinineTranfo 2013
194910MalesSubjects living in Central ItalyItalyITUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)7498.056.35235.546.4152.14548.422.32110.39ug/g56.4 ug/g52.1 ug/gDensityCreatinineTranfo 2013
194970ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)10438.130.947.1ug/g38.1 ug/gDensityCreatinineKasper-Sonnenberg 2012
195240MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)103100.042.334.152.5ug/g42.3 ug/gDensityCreatinineKasper-Sonnenberg 2012
195490AllPregnant women in two French regionsFranceFRELFE (Étude Longitudinale Francaise depuis l’Enfance)deliveryUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)279181.6799.70.034.3675.27593.0ug/g181.6 ug/g34.3 ug/gDensityCreatinineZeman 2013
195740AllMothers in southern SwedenSwedenSEUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)3837101.0160.05.539.0119.0862.0ug/g101.0 ug/g39.0 ug/gDensityCreatinineHogberg 2008
195840AllMothers in southern SwedenSwedenSESerum, unspecifiedLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)3671.22.30.50.50.514.0ng/mL0.0 mg/L0.0 mg/LCrudeHogberg 2008
196050AllMinority pregnant women in New York cityUnited StatesUSCCCEH (Columbia Center for Children's Environmental Health)pregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)164243.037.0103.0199.0489.03184.0198.0298.0ng/mL0.2 mg/L0.2 mg/LDensitySpecific gravityJust 2010
196080AllPregnant womenNorwayNOMoBa (Norwegian Mother and Child Cohort)Urine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)110405.87ug/g405.9 ug/gDensityCreatinineYe 2009
196240AllPregnant womenNetherlandsNLGeneration R studyUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)100465.81ug/g465.8 ug/gDensityCreatinineYe 2009
196380AllPregnant womenUnited StatesUSNHANESUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)111464.31ug/g464.3 ug/gDensityCreatinineYe 2009
196820UrbanUrban and rural premenstrual girlsEgyptEGUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)28562.2331.28.8121.89288.0ng/mL0.6 mg/L0.1 mg/LDensitySpecific gravityColacino 2011
196980RuralUrban and rural premenstrual girlsEgyptEGUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)29498.4239.54.663.06462.0ng/mL0.5 mg/L0.1 mg/LDensitySpecific gravityColacino 2011
197060AllMinority pregnant women in New York cityUnited StatesUSCCCEH (Columbia Center for Children's Environmental Health)Urine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)246100.0232.036.8103.0202.0481.02753.0199.0272.0ng/mL0.2 mg/L0.2 mg/LCrudeAdibi 2008
197670AllGeneral populationUnited StatesUSNHANES 1999-2000Urine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)2536163.033.064.7141.0360.0898.01950.0148.0179.0ug/g163.0 ug/g141.0 ug/gDensityCreatinineSilva 2004
197810AllGirls from New York City, New York, Cincinnati, Ohio, and northern CaliforniaUnited StatesUSUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)90100.075.73.95.383.22580.0ug/L0.1 mg/L0.1 mg/LCrudeWolff 2007
198670FemalesSubjects from three citiesChinaCNUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)9977.425.68.725.280.41850.0ng/mL0.1 mg/L0.0 mg/L0.0 mg/LCrudeGuo 2011
198810MalesSubjects from three citiesChinaCNUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)8461.918.58.118.433.41330.0ng/mL0.1 mg/L0.0 mg/L0.0 mg/LCrudeGuo 2011
198950AllSubjects from three citiesChinaCNUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)18318.7ug/g18.7 ug/gDensityCreatinineGuo 2011
199090ChineseSubjects from seven asian countriesChinaCNUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)4022.517.0ng/mL0.0 mg/L0.0 mg/LCrudeGuo 2011
199230IndianSubjects from seven asian countriesIndiaINUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)22132.0120.0ng/mL0.1 mg/L0.1 mg/LCrudeGuo 2011
199370JapaneseSubjects from seven asian countriesJapanJPUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)3512.110.0ng/mL0.0 mg/L0.0 mg/LCrudeGuo 2011
199510KuwaitiSubjects from seven asian countriesKuwaitKWUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)46272.0296.0ng/mL0.3 mg/L0.3 mg/LCrudeGuo 2011
199650MalaysianSubjects from seven asian countriesMalaysiaMYUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)2938.638.6ng/mL0.0 mg/L0.0 mg/LCrudeGuo 2011
199790VietnameseSubjects from seven asian countriesViet NamVNUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)306.55.8ng/mL0.0 mg/L0.0 mg/LCrudeGuo 2011
199930KoreanSubjects from seven asian countriesKorea, Republic ofKRUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)6013.712.2ng/mL0.0 mg/L0.0 mg/LCrudeGuo 2011
200110AllInhabitants of Erlangen and surroundingsGermanyDEUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)85165.0301.07.973.3673.02319.0ug/g165.0 ug/g73.3 ug/gDensityCreatinineKoch 2003
201380AllGeneral populationCanadaCACHMS (Canadian Health Measures Survey)Urine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)323656.021.449.1138.2824.246.665.3ug/L0.1 mg/L0.0 mg/LCrudeSaravanabhavan 2013
201460MalesGeneral populationCanadaCACHMS (Canadian Health Measures Survey)Urine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)163058.822.150.4151.1926.446.670.9ug/L0.1 mg/L0.1 mg/LCrudeSaravanabhavan 2013
201600AllGeneral populationCanadaCACHMS (Canadian Health Measures Survey)Urine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)323662.125.454.2127.8692.853.870.3ug/g62.1 ug/g54.2 ug/gDensityCreatinineSaravanabhavan 2013
201670MalesGeneral populationCanadaCACHMS (Canadian Health Measures Survey)Urine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)163054.921.746.5116.2695.246.663.1ug/g54.9 ug/g46.5 ug/gDensityCreatinineSaravanabhavan 2013
201740ChildrenGeneral populationCanadaCACHMS (Canadian Health Measures Survey)Urine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)103725.911.123.654.3210.720.830.9ug/L0.0 mg/L0.0 mg/LCrudeSaravanabhavan 2013
201870AllInfants from the Munich areaGermanyDEINES (Integrated Exposure Assessment Survey)baseline; 1 day; 2 days; 3 days; 4 days; 5 days; 6 daysUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)2590.035.825.4119.9266.0ug/L0.0 mg/L0.0 mg/LCrudeFromme 2013
202080AllPregnant women in JerusalemIsraelILpregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)19270.029.4140.514956.1ug/g270.0 ug/g140.5 ug/gDensityCreatinineBerman 2009
202330MothersPregnant women and their childrenSpainESINMA (Environment and Childhood)pregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)118324.0519.0ng/mL0.3 mg/LCrudeCasas 2011
202490ChildrenPregnant women and their childrenSpainESINMA (Environment and Childhood)Urine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)19755.01282.0ng/mL0.8 mg/LCrudeCasas 2011
202520AllOffice workersTaiwanTWUrine, spotGC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)6018.04.84.288.7193.6ng/mL0.0 mg/LCrudeChen 2008
202560AllChildren and adolescentsDenmarkDKCopenhagen Puberty Study 2006–2008Urine, 24-hLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)1294.911.017.029.055.0134.0171.0585.0ng/mL0.0 mg/LCrudeFrederiksen 2011
202720AllChildren and adolescentsDenmarkDKCopenhagen Puberty Study 2006–2008Urine, first morning spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)1293.718.030.046.093.0137.0274.01238.0ng/mL0.0 mg/LCrudeFrederiksen 2011
203130AllPregnant womenPeruPEbaseline; 3 months; 6 monthsUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)7998.032.224.941.6ug/L0.0 mg/LCrudeIrvin 2010
203220AllPregnant womenPeruPEbaseline; 3 months; 6 monthsUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)7899.067.453.984.1ug/g67.4 ug/gDensityCreatinineIrvin 2010
203320AllPregnant women from RotterdamNetherlandsNLGeneration R studypregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)10097.0112.05.637.9117.0425.04330.0ug/L0.1 mg/L0.1 mg/LCrudeYe 2008
203480AllPregnant women from RotterdamNetherlandsNLGeneration R studypregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)100173.04.771.9222.0487.07160.0ug/g173.0 ug/g222.0 ug/gDensityCreatinineYe 2008
203980AllCouples seeking infertility evaluation and treatment at the Massachusetts General Hospital Fertility CenterUnited StatesUSbaseline; 35 days; 70 daysUrine, spotLC-ID-MS/MSMonoethyl phthalate (MEP)26981.611.225.369.5249.0727.01290.027200.0ng/mL0.1 mg/L0.1 mg/LCrudeMeeker 2012
204050AllCouples seeking infertility evaluation and treatment at the Massachusetts General Hospital Fertility CenterUnited StatesUSbaseline; 35 days; 70 daysUrine, spotLC-ID-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)269111.016.336.396.2329.0937.01750.032900.0ng/mL0.1 mg/L0.1 mg/LCrudeMeeker 2012
204710AllResidents of the Tokyo-Yokohama areaJapanJPUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)3618.0ug/L0.0 mg/LCrudeItoh 2007
204770AllWomenUnited StatesUSbaseline; 1 day; 28 days; 29 days; 30 days; 31 days; 32 days; 33 days; 34 daysUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)10122.0154.610.82722.0ng/mL0.1 mg/LCrudeMarcus 2010
204820AllWomenUnited StatesUSbaseline; 1 day; 28 days; 29 days; 30 days; 31 days; 32 days; 33 days; 34 daysUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)10139.0153.221.02074.0ug/g139.0 ug/gDensityCreatinineMarcus 2010
20498205031AllWomenUnited StatesUSNHS (Nurses' Health Study)baseline; 2 yearsUrine, first morning spotLC-ID-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)40700.7108.2724.24611.2pmol/mg0.7 umol/g0.7 umol/gDensityCreatinineTownsend 2013

Intake values

No data available

Correlation values

No data available

Reproducibility values

IDMst. IDSubject groupPopulationCountryCountry codeCohortTime definitionBiological specimenExperimental methodBiomarkerBiomarker detailArithmetic meanGeometric meanMedianUnitAdjusted onReproducibility sizeICCICC 95% CI lowerICC 95% CI upperCV% WSCV% BSVAR WSVAR BSPublication
9818232AllHmong womenUnited StatesUSFox River Environment and Diet Study cohort in Green Bay, Wisconsinbaseline; 15 days; 29.5 daysUrine, first morning spotLC-ID-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)59.662.3ug/gCreatinine450.610.530.66Peck 2010
31418672AllWomen in Washington DCUnited StatesUSA study to screen for uterine fibroids in 1996-1997baseline; 1 dayUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)183.0134.8ug/gCreatinine350.60.360.76Hoppin 2002
33918684AllMinority childrenUnited StatesUSbaseline; 2 weeks; 1 month; 2 months, 3 months; 6 monthsUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)176.4149.5ug/gCreatinine350.260.70.25Teitelbaum 2008
38318730AllParticipants in a study of reproductive healthDenmarkDKbaseline; 40 days; 83 daysUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)53.1ng/mL330.330.110.551.0740.524Frederiksen 2013
39118746AllParticipants in a study of reproductive healthDenmarkDKbaseline; 4 daysUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)70.4ng/mL330.650.390.811.011.873Frederiksen 2013
40118760AllParticipants in a study of reproductive healthDenmarkDKbaseline; 40 days; 83 daysUrine, 24-hLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)38.6ng/mL330.510.30.70.7810.826Frederiksen 2013
44018812AllPregnant women living in the Northern karst area of Puerto RicoPuerto RicoPRPROTECT (Puerto Rico Testsite for Exploring Contamination Threats)baseline; 4 weeks; 8 weeksUrine, spotLC-ID-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)102.299.2ng/mL1390.430.330.54Cantonwine 2014
45218828AllPregnant women living in the Northern karst area of Puerto RicoPuerto RicoPRPROTECT (Puerto Rico Testsite for Exploring Contamination Threats)baseline; 4 weeks; 8 weeksUrine, spotLC-ID-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)ng/mLSpecific gravity1380.440.340.55Cantonwine 2014
49918895AllWomen seeking evaluation and treatment for infertility at the Massachusetts General HospitalUnited StatesUSEARTH (Environment and Reproductive Health)baseline; 12 weeksUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)61.0ug/LSpecific gravity1370.56Braun 2012
50718903AllWomen seeking evaluation and treatment for infertility at the Massachusetts General HospitalUnited StatesUSEARTH (Environment and Reproductive Health)baseline; 15 weeks; 28 weeksUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)55.0ug/LSpecific gravity1370.5Braun 2012
51218905AllSubjects in the metropolitan Atlanta area non-occupationally exposed to phthalatesUnited StatesUSbaseline; 1 day; 2 days; 3 days; 4 days; 5 days; 6 daysUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)105.075.0ug/gCreatinine80.77Preau 2010
51018907AllSubjects in the metropolitan Atlanta area non-occupationally exposed to phthalatesUnited StatesUSbaseline; 1 day; 2 days; 3 days; 4 days; 5 days; 6 daysUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)86.745.0ug/gCreatinine80.91Preau 2010
51418909AllSubjects in the metropolitan Atlanta area non-occupationally exposed to phthalatesUnited StatesUSbaseline; 1 day; 2 days; 3 days; 4 days; 5 days; 6 daysUrine, 24-hLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)136.097.1ug/gCreatinine80.94Preau 2010
51820498AllWomenUnited StatesUSNHS (Nurses' Health Study)baseline; 2 yearsUrine, first morning spotLC-ID-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)700.7724.2pmol/mgCreatinine400.330.130.630.80.4Townsend 2013
79019722Variability subgroupMinority pregnant women in New York cityUnited StatesUSCCCEH (Columbia Center for Children's Environmental Health)baseline; 2 weeks; 4 weeksUrine, spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)ng/mL280.3Adibi 2008
85820398AllCouples seeking infertility evaluation and treatment at the Massachusetts General Hospital Fertility CenterUnited StatesUSbaseline; 35 days; 70 daysUrine, spotLC-ID-MS/MSMonoethyl phthalate (MEP)81.669.5ng/mL2690.50.430.57Meeker 2012
86520405AllCouples seeking infertility evaluation and treatment at the Massachusetts General Hospital Fertility CenterUnited StatesUSbaseline; 35 days; 70 daysUrine, spotLC-ID-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)111.096.2ng/mL2690.490.420.56Meeker 2012
89420477AllWomenUnited StatesUSbaseline; 1 day; 28 days; 29 days; 30 days; 31 days; 32 days; 33 days; 34 daysUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)122.0ng/mL100.68Marcus 2010