DBP metabolites

ID1450
NameDBP metabolites
SynonymsDi-butyl-phthalates metabolites; DnBP and DiBP metabolites; Mono-butyl-phthalates (MBP)
StructureThumb
DescriptionMono-n-butyl (DnBP metabolite) and mono-iso-butyl-phthalate (DiBP metabolite).
GroupPhthalates
Sub-groupPhthalate monoesters
Exposure sourcePollution
UsePlasticizers
CAS number
PubChem ID
ChEBI ID
FooDB ID
HMDB ID

Biomarker measurements

Biomarker concentration values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed asPublication
187310AllParticipants in a study of reproductive healthDenmarkDKbaseline; 40 days; 83 daysUrine, first morning spotLC-MS/MS after enzymatic hydrolysisDBP metabolitesMono-isobutyl phthalate (MiBP)
Mono-n-butyl phthalate (MnBP)
33100.020.844.271.1116.0189.0318.0912.0ng/mL0.1 mg/LCrudeFrederiksen 2013
187470AllParticipants in a study of reproductive healthDenmarkDKbaseline; 4 daysUrine, spotLC-MS/MS after enzymatic hydrolysisDBP metabolitesMono-isobutyl phthalate (MiBP)
Mono-n-butyl phthalate (MnBP)
33100.06.2929.274.8106.0150.0283.0366.0ng/mL0.1 mg/LCrudeFrederiksen 2013
187610AllParticipants in a study of reproductive healthDenmarkDKbaseline; 40 days; 83 daysUrine, 24-hLC-MS/MS after enzymatic hydrolysisDBP metabolitesMono-isobutyl phthalate (MiBP)
Mono-n-butyl phthalate (MnBP)
33100.018.428.151.874.8123.0301.01640.0ng/mL0.1 mg/LCrudeFrederiksen 2013
18916205031AllWomenUnited StatesUSNHS (Nurses' Health Study)baseline; 2 yearsUrine, first morning spotLC-ID-MS/MS after enzymatic hydrolysisDBP metabolitesMono-isobutyl phthalate (MiBP)
Mono-n-butyl phthalate (MnBP)
40190.952.8177.71157.2pmol/mg0.2 umol/g0.2 umol/gDensityCreatinineTownsend 2013
194480ChildrenMother-child pairs in rural and urban DenmarkDenmarkDKUrine, first morning spotLC-MS/MS after enzymatic hydrolysisDBP metabolitesMono-isobutyl phthalate (MiBP)
Mono-n-butyl phthalate (MnBP)
145108.024.038.064.096.0124.0244.0590.0ug/g108.0 ug/g96.0 ug/gDensityCreatinineFrederiksen 2013
194650MothersMother-child pairs in rural and urban DenmarkDenmarkDKUrine, first morning spotLC-MS/MS after enzymatic hydrolysisDBP metabolitesMono-isobutyl phthalate (MiBP)
Mono-n-butyl phthalate (MnBP)
14567.018.028.044.061.082.0141.0186.0ug/g67.0 ug/g61.0 ug/gDensityCreatinineFrederiksen 2013
202570AllChildren and adolescentsDenmarkDKCopenhagen Puberty Study 2006–2008Urine, 24-hLC-MS/MS after enzymatic hydrolysisDBP metabolitesMono-isobutyl phthalate (MiBP)
Mono-n-butyl phthalate (MnBP)
12919.044.068.0111.0193.0290.0379.0595.0ng/mL0.1 mg/LCrudeFrederiksen 2011
202730AllChildren and adolescentsDenmarkDKCopenhagen Puberty Study 2006–2008Urine, first morning spotLC-MS/MS after enzymatic hydrolysisDBP metabolitesMono-isobutyl phthalate (MiBP)
Mono-n-butyl phthalate (MnBP)
12937.072.0119.0188.0275.0363.0397.01748.0ng/mL0.2 mg/LCrudeFrederiksen 2011

Intake values

No data available

Correlation values

No data available

Reproducibility values

IDMst. IDSubject groupPopulationCountryCountry codeCohortTime definitionBiological specimenExperimental methodBiomarkerBiomarker detailArithmetic meanGeometric meanMedianUnitAdjusted onReproducibility sizeICCICC 95% CI lowerICC 95% CI upperCV% WSCV% BSVAR WSVAR BSPublication
38418731AllParticipants in a study of reproductive healthDenmarkDKbaseline; 40 days; 83 daysUrine, first morning spotLC-MS/MS after enzymatic hydrolysisDBP metabolitesMono-isobutyl phthalate (MiBP)
Mono-n-butyl phthalate (MnBP)
116.0ng/mL330.370.150.590.3160.187Frederiksen 2013
39418747AllParticipants in a study of reproductive healthDenmarkDKbaseline; 4 daysUrine, spotLC-MS/MS after enzymatic hydrolysisDBP metabolitesMono-isobutyl phthalate (MiBP)
Mono-n-butyl phthalate (MnBP)
106.0ng/mL330.390.050.640.2850.179Frederiksen 2013
39518761AllParticipants in a study of reproductive healthDenmarkDKbaseline; 40 days; 83 daysUrine, 24-hLC-MS/MS after enzymatic hydrolysisDBP metabolitesMono-isobutyl phthalate (MiBP)
Mono-n-butyl phthalate (MnBP)
74.8ng/mL330.560.360.730.1670.211Frederiksen 2013
52118916AllWomenUnited StatesUSNHS (Nurses' Health Study)baseline; 2 yearsUrine, first morning spotLC-ID-MS/MS after enzymatic hydrolysisDBP metabolitesMono-isobutyl phthalate (MiBP)
Mono-n-butyl phthalate (MnBP)
190.9177.7pmol/mgCreatinine400.450.230.690.370.31Townsend 2013