Mono(carboxy-isooctyl) phthalate (MCOP)

ID1455
NameMono(carboxy-isooctyl) phthalate (MCOP)
SynonymsMono(2,6-dimethyl-6-carboxyhexyl) phthalate; MCiOP
StructureThumb
Description
GroupPhthalates
Sub-groupPhthalate monoesters
Exposure sourcePollution
UsePlasticizers
CAS number
PubChem ID
ChEBI ID
FooDB ID
HMDB ID

Biomarker measurements

Biomarker concentration values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed asPublication
18741187431AllParticipants in a study of reproductive healthDenmarkDKbaseline; 40 days; 83 daysUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono(carboxy-isooctyl) phthalate (MCOP)33100.01.283.526.9411.018.538.3166.0ng/mL0.0 mg/LCrudeFrederiksen 2013
18757187591AllParticipants in a study of reproductive healthDenmarkDKbaseline; 4 daysUrine, spotLC-MS/MS after enzymatic hydrolysisMono(carboxy-isooctyl) phthalate (MCOP)33100.00.761.515.378.8414.849.8101.0ng/mL0.0 mg/LCrudeFrederiksen 2013
18771187731AllParticipants in a study of reproductive healthDenmarkDKbaseline; 40 days; 83 daysUrine, 24-hLC-MS/MS after enzymatic hydrolysisMono(carboxy-isooctyl) phthalate (MCOP)33100.01.362.644.318.414.757.2161.0ng/mL0.0 mg/LCrudeFrederiksen 2013
188160AllPregnant women living in the Northern karst area of Puerto RicoPuerto RicoPRPROTECT (Puerto Rico Testsite for Exploring Contamination Threats)baseline; 4 weeks; 8 weeksUrine, spotLC-ID-MS/MS after enzymatic hydrolysisMono(carboxy-isooctyl) phthalate (MCOP)139100.016.47.114.234.1137.01230.014.617.0ng/mL0.0 mg/L0.0 mg/LCrudeCantonwine 2014
193580AllDemographically diverse group of U.S. adults of both sexesUnited StatesUSUrine, spotLC-MS/MS after enzymatic hydrolysisMono(carboxy-isooctyl) phthalate (MCOP)12997.07.82.03.98.418.327.346.2ng/mL0.0 mg/L0.0 mg/LCrudeSilva 2006
193620AllDemographically diverse group of U.S. adults of both sexesUnited StatesUSUrine, spotLC-MS/MSMono(carboxy-isooctyl) phthalate (MCOP)8298.06.12.02.95.111.622.8ng/mL0.0 mg/L0.0 mg/LCrudeSilva 2006
193880AllPrimary school starters at the City of FrankfurtGermanyDEUrine, spotLC-MS/MS after enzymatic hydrolysisMono(carboxy-isooctyl) phthalate (MCOP)11199.031.120.219.791.6287.023.838.5ug/g31.1 ug/g20.2 ug/g19.7 ug/gDensityCreatinineKoch 2011
19460194611ChildrenMother-child pairs in rural and urban DenmarkDenmarkDKUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono(carboxy-isooctyl) phthalate (MCOP)14524.02.03.05.08.214.037.01556.0ug/g24.0 ug/g8.2 ug/gDensityCreatinineFrederiksen 2013
19477194781MothersMother-child pairs in rural and urban DenmarkDenmarkDKUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono(carboxy-isooctyl) phthalate (MCOP)1459.92.03.35.29.937.0106.0ug/g9.9 ug/g5.2 ug/gDensityCreatinineFrederiksen 2013
195600AllPregnant women in two French regionsFranceFRELFE (Étude Longitudinale Francaise depuis l’Enfance)deliveryUrine, spotLC-MS/MS after enzymatic hydrolysisMono(carboxy-isooctyl) phthalate (MCOP)27917.725.00.97.450.2356.4ug/g17.7 ug/g7.4 ug/gDensityCreatinineZeman 2013
196800UrbanUrban and rural premenstrual girlsEgyptEGUrine, spotLC-MS/MS after enzymatic hydrolysisMono(carboxy-isooctyl) phthalate (MCOP)289.02.30.43.849.0ng/mL0.0 mg/L0.0 mg/LDensitySpecific gravityColacino 2011
196960RuralUrban and rural premenstrual girlsEgyptEGUrine, spotLC-MS/MS after enzymatic hydrolysisMono(carboxy-isooctyl) phthalate (MCOP)294.00.90.62.724.5ng/mL0.0 mg/L0.0 mg/LDensitySpecific gravityColacino 2011
202030AllInfants from the Munich areaGermanyDEINES (Integrated Exposure Assessment Survey)baseline; 1 day; 2 days; 3 days; 4 days; 5 days; 6 daysUrine, spotLC-MS/MS after enzymatic hydrolysisMono(carboxy-isooctyl) phthalate (MCOP)2552.04.12.58.736.3ug/L0.0 mg/L0.0 mg/LCrudeFromme 2013
202100AllPregnant women in JerusalemIsraelILpregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMono(carboxy-isooctyl) phthalate (MCOP)193.13.816.2ug/g3.1 ug/g3.8 ug/gDensityCreatinineBerman 2009
202240MothersPregnant women and their childrenSpainESINMA (Environment and Childhood)pregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMono(carboxy-isooctyl) phthalate (MCOP)1184.03.5ng/mL0.0 mg/LCrudeCasas 2011
202400ChildrenPregnant women and their childrenSpainESINMA (Environment and Childhood)Urine, spotLC-MS/MS after enzymatic hydrolysisMono(carboxy-isooctyl) phthalate (MCOP)197.56.4ng/mL0.0 mg/LCrudeCasas 2011
204010AllCouples seeking infertility evaluation and treatment at the Massachusetts General Hospital Fertility CenterUnited StatesUSbaseline; 35 days; 70 daysUrine, spotLC-ID-MS/MSMono(carboxy-isooctyl) phthalate (MCOP)2693.21.33.28.121.240.7709.0ng/mL0.0 mg/L0.0 mg/LCrudeMeeker 2012
204080AllCouples seeking infertility evaluation and treatment at the Massachusetts General Hospital Fertility CenterUnited StatesUSbaseline; 35 days; 70 daysUrine, spotLC-ID-MS/MS after enzymatic hydrolysisMono(carboxy-isooctyl) phthalate (MCOP)2697.01.22.86.416.351.994.72250.0ng/mL0.0 mg/L0.0 mg/LCrudeMeeker 2012

Intake values

No data available

Correlation values

No data available

Reproducibility values

IDMst. IDSubject groupPopulationCountryCountry codeCohortTime definitionBiological specimenExperimental methodBiomarkerBiomarker detailArithmetic meanGeometric meanMedianUnitAdjusted onReproducibility sizeICCICC 95% CI lowerICC 95% CI upperCV% WSCV% BSVAR WSVAR BSPublication
44418816AllPregnant women living in the Northern karst area of Puerto RicoPuerto RicoPRPROTECT (Puerto Rico Testsite for Exploring Contamination Threats)baseline; 4 weeks; 8 weeksUrine, spotLC-ID-MS/MS after enzymatic hydrolysisMono(carboxy-isooctyl) phthalate (MCOP)16.414.2ng/mL1390.290.190.41Cantonwine 2014
45618832AllPregnant women living in the Northern karst area of Puerto RicoPuerto RicoPRPROTECT (Puerto Rico Testsite for Exploring Contamination Threats)baseline; 4 weeks; 8 weeksUrine, spotLC-ID-MS/MS after enzymatic hydrolysisMono(carboxy-isooctyl) phthalate (MCOP)ng/mLSpecific gravity1380.280.180.4Cantonwine 2014
86120401AllCouples seeking infertility evaluation and treatment at the Massachusetts General Hospital Fertility CenterUnited StatesUSbaseline; 35 days; 70 daysUrine, spotLC-ID-MS/MSMono(carboxy-isooctyl) phthalate (MCOP)3.23.2ng/mL2690.130.060.25Meeker 2012
86820408AllCouples seeking infertility evaluation and treatment at the Massachusetts General Hospital Fertility CenterUnited StatesUSbaseline; 35 days; 70 daysUrine, spotLC-ID-MS/MS after enzymatic hydrolysisMono(carboxy-isooctyl) phthalate (MCOP)7.06.4ng/mL2690.140.070.25Meeker 2012