DiNP metabolites

ID1456
NameDiNP metabolites
SynonymsDi-iso-nonyl-phthalate metabolites
StructureThumb
Description
GroupPhthalates
Sub-groupPhthalate monoesters
Exposure sourcePollution
UsePlasticizers
CAS number
PubChem ID
ChEBI ID
FooDB ID
HMDB ID

Biomarker measurements

Biomarker concentration values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed asPublication
187430AllParticipants in a study of reproductive healthDenmarkDKbaseline; 40 days; 83 daysUrine, first morning spotLC-MS/MS after enzymatic hydrolysisDiNP metabolitesMono(carboxy-isooctyl) phthalate (MCOP)
Mono-hydroxy-isononyl phthalate (OH-MiNP)
Mono-isononyl phthalate (MiNP)
Mono-oxo-isononyl phthalate (oxo-MiNP)
332.48.3921.937.452.5138.0503.0ng/mL0.0 mg/LCrudeFrederiksen 2013
187590AllParticipants in a study of reproductive healthDenmarkDKbaseline; 4 daysUrine, spotLC-MS/MS after enzymatic hydrolysisDiNP metabolitesMono(carboxy-isooctyl) phthalate (MCOP)
Mono-hydroxy-isononyl phthalate (OH-MiNP)
Mono-isononyl phthalate (MiNP)
Mono-oxo-isononyl phthalate (oxo-MiNP)
331.743.5214.8922.540.5113.0289.0ng/mL0.0 mg/LCrudeFrederiksen 2013
187730AllParticipants in a study of reproductive healthDenmarkDKbaseline; 40 days; 83 daysUrine, 24-hLC-MS/MS after enzymatic hydrolysisDiNP metabolitesMono(carboxy-isooctyl) phthalate (MCOP)
Mono-hydroxy-isononyl phthalate (OH-MiNP)
Mono-isononyl phthalate (MiNP)
Mono-oxo-isononyl phthalate (oxo-MiNP)
333.597.7514.624.941.4139.0594.0ng/mL0.0 mg/LCrudeFrederiksen 2013
194610ChildrenMother-child pairs in rural and urban DenmarkDenmarkDKUrine, first morning spotLC-MS/MS after enzymatic hydrolysisDiNP metabolitesMono(carboxy-isooctyl) phthalate (MCOP)
Mono-hydroxy-isononyl phthalate (OH-MiNP)
Mono-isononyl phthalate (MiNP)
Mono-oxo-isononyl phthalate (oxo-MiNP)
14561.04.07.212.022.038.0102.03626.0ug/g61.0 ug/g22.0 ug/gDensityCreatinineFrederiksen 2013
194780MothersMother-child pairs in rural and urban DenmarkDenmarkDKUrine, first morning spotLC-MS/MS after enzymatic hydrolysisDiNP metabolitesMono(carboxy-isooctyl) phthalate (MCOP)
Mono-hydroxy-isononyl phthalate (OH-MiNP)
Mono-isononyl phthalate (MiNP)
Mono-oxo-isononyl phthalate (oxo-MiNP)
14524.00.883.97.612.024.081.0240.0ug/g24.0 ug/g12.0 ug/gDensityCreatinineFrederiksen 2013
195170ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisDiNP metabolitesMono-carboxy-isononyl phthalate (cx-MiNP)
Mono-hydroxy-isononyl phthalate (OH-MiNP)
Mono-oxo-isononyl phthalate (oxo-MiNP)
10431.928.535.8ug/g31.9 ug/gDensityCreatinineKasper-Sonnenberg 2012
195430MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisDiNP metabolitesMono-carboxy-isononyl phthalate (cx-MiNP)
Mono-hydroxy-isononyl phthalate (OH-MiNP)
Mono-oxo-isononyl phthalate (oxo-MiNP)
10318.315.821.3ug/g18.3 ug/gDensityCreatinineKasper-Sonnenberg 2012
202680AllChildren and adolescentsDenmarkDKCopenhagen Puberty Study 2006–2008Urine, 24-hLC-MS/MS after enzymatic hydrolysisDiNP metabolitesMono(carboxy-isooctyl) phthalate (MCOP)
Mono-hydroxy-isononyl phthalate (OH-MiNP)
Mono-isononyl phthalate (MiNP)
Mono-oxo-isononyl phthalate (oxo-MiNP)
1293.012.017.031.051.083.0114.0281.0ng/mL0.0 mg/LCrudeFrederiksen 2011

Intake values

No data available

Correlation values

No data available

Reproducibility values

IDMst. IDSubject groupPopulationCountryCountry codeCohortTime definitionBiological specimenExperimental methodBiomarkerBiomarker detailArithmetic meanGeometric meanMedianUnitAdjusted onReproducibility sizeICCICC 95% CI lowerICC 95% CI upperCV% WSCV% BSVAR WSVAR BSPublication
38918743AllParticipants in a study of reproductive healthDenmarkDKbaseline; 40 days; 83 daysUrine, first morning spotLC-MS/MS after enzymatic hydrolysisDiNP metabolitesMono(carboxy-isooctyl) phthalate (MCOP)
Mono-hydroxy-isononyl phthalate (OH-MiNP)
Mono-isononyl phthalate (MiNP)
Mono-oxo-isononyl phthalate (oxo-MiNP)
37.4ng/mL330.250.040.490.5990.2Frederiksen 2013
39818759AllParticipants in a study of reproductive healthDenmarkDKbaseline; 4 daysUrine, spotLC-MS/MS after enzymatic hydrolysisDiNP metabolitesMono(carboxy-isooctyl) phthalate (MCOP)
Mono-hydroxy-isononyl phthalate (OH-MiNP)
Mono-isononyl phthalate (MiNP)
Mono-oxo-isononyl phthalate (oxo-MiNP)
22.5ng/mL330.080.00.410.790.066Frederiksen 2013
40418773AllParticipants in a study of reproductive healthDenmarkDKbaseline; 40 days; 83 daysUrine, 24-hLC-MS/MS after enzymatic hydrolysisDiNP metabolitesMono(carboxy-isooctyl) phthalate (MCOP)
Mono-hydroxy-isononyl phthalate (OH-MiNP)
Mono-isononyl phthalate (MiNP)
Mono-oxo-isononyl phthalate (oxo-MiNP)
24.9ng/mL330.260.050.50.5770.203Frederiksen 2013