Mono-carboxy-isononyl phthalate (cx-MiNP)

ID1465
NameMono-carboxy-isononyl phthalate (cx-MiNP)
SynonymsMono(carboxy-isononyl) phthalate; Mono(carboxy-isononyl) phthalates; MCINP; MCNP; 7-cx-MiNP; 7-Carboxy-(mono-methyl-heptyl) phthalate; Mono(4-methyl-7-carboxyheptyl) phthalate; Mono(4-methyl-7-carboxy-heptyl) phthalate; 7-cx-MMeHP; 7cx-MMeHP
StructureThumb
DescriptionMetabolite of mono-isononyl phthalate (MiNP); secondary metabolite of di-isononyl phthalate (DiNP). Structure for 4-methyl-7-carboxy- is represented.
GroupPhthalates
Sub-groupPhthalate monoesters
Exposure sourcePollution
UsePlasticizers
CAS number
PubChem ID
ChEBI ID
FooDB ID
HMDB ID

Biomarker measurements

Biomarker concentration values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed asPublication
188150AllPregnant women living in the Northern karst area of Puerto RicoPuerto RicoPRPROTECT (Puerto Rico Testsite for Exploring Contamination Threats)baseline; 4 weeks; 8 weeksUrine, spotLC-ID-MS/MS after enzymatic hydrolysisMono-carboxy-isononyl phthalate (cx-MiNP)13999.72.31.22.23.612.159.82.12.5ng/mL0.0 mg/L0.0 mg/LCrudeCantonwine 2014
192980AllChildrenGermanyDEGerES IV (German Environmental Survey IV)Urine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-carboxy-isononyl phthalate (cx-MiNP)59913.812.742.558.9195.012.914.8ug/L0.0 mg/L0.0 mg/LCrudeBecker 2009
19516195171ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-carboxy-isononyl phthalate (cx-MiNP)104100.010.08.911.2ug/g10.0 ug/gDensityCreatinineKasper-Sonnenberg 2012
19542195431MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-carboxy-isononyl phthalate (cx-MiNP)103100.04.74.05.4ug/g4.7 ug/gDensityCreatinineKasper-Sonnenberg 2012
196790UrbanUrban and rural premenstrual girlsEgyptEGUrine, spotLC-MS/MS after enzymatic hydrolysisMono-carboxy-isononyl phthalate (cx-MiNP)282.60.60.31.511.2ng/mL0.0 mg/L0.0 mg/LDensitySpecific gravityColacino 2011
196950RuralUrban and rural premenstrual girlsEgyptEGUrine, spotLC-MS/MS after enzymatic hydrolysisMono-carboxy-isononyl phthalate (cx-MiNP)292.30.60.21.113.7ng/mL0.0 mg/L0.0 mg/LDensitySpecific gravityColacino 2011
200230MothersPregnant women and their childrenTaiwanTWpregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMono-carboxy-isononyl phthalate (cx-MiNP)1000.920.080.41283.00.61.4ug/g0.9 ug/g0.4 ug/gDensityCreatinineLin 2011
200660Children aged 5-6 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono-carboxy-isononyl phthalate (cx-MiNP)5927.6122.3620.0936.5ug/g27.6 ug/g22.4 ug/gDensityCreatinineLin 2011
200770Children aged 2-3 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono-carboxy-isononyl phthalate (cx-MiNP)3027.821.1815.948.5ug/g27.8 ug/g21.2 ug/gDensityCreatinineLin 2011
202090AllPregnant women in JerusalemIsraelILpregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMono-carboxy-isononyl phthalate (cx-MiNP)191.71.513.9ug/g1.7 ug/g1.5 ug/gDensityCreatinineBerman 2009
202230MothersPregnant women and their childrenSpainESINMA (Environment and Childhood)pregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMono-carboxy-isononyl phthalate (cx-MiNP)1182.82.2ng/mL0.0 mg/LCrudeCasas 2011
202390ChildrenPregnant women and their childrenSpainESINMA (Environment and Childhood)Urine, spotLC-MS/MS after enzymatic hydrolysisMono-carboxy-isononyl phthalate (cx-MiNP)194.04.1ng/mL0.0 mg/LCrudeCasas 2011
204000AllCouples seeking infertility evaluation and treatment at the Massachusetts General Hospital Fertility CenterUnited StatesUSbaseline; 35 days; 70 daysUrine, spotLC-ID-MS/MSMono-carboxy-isononyl phthalate (cx-MiNP)2691.31.22.77.119.3355.0ng/mL0.0 mg/L0.0 mg/LCrudeMeeker 2012
204070AllCouples seeking infertility evaluation and treatment at the Massachusetts General Hospital Fertility CenterUnited StatesUSbaseline; 35 days; 70 daysUrine, spotLC-ID-MS/MS after enzymatic hydrolysisMono-carboxy-isononyl phthalate (cx-MiNP)2692.51.12.54.911.738.21680.0ng/mL0.0 mg/L0.0 mg/LCrudeMeeker 2012

Intake values

No data available

Correlation values

No data available

Reproducibility values

IDMst. IDSubject groupPopulationCountryCountry codeCohortTime definitionBiological specimenExperimental methodBiomarkerBiomarker detailArithmetic meanGeometric meanMedianUnitAdjusted onReproducibility sizeICCICC 95% CI lowerICC 95% CI upperCV% WSCV% BSVAR WSVAR BSPublication
44318815AllPregnant women living in the Northern karst area of Puerto RicoPuerto RicoPRPROTECT (Puerto Rico Testsite for Exploring Contamination Threats)baseline; 4 weeks; 8 weeksUrine, spotLC-ID-MS/MS after enzymatic hydrolysisMono-carboxy-isononyl phthalate (cx-MiNP)2.32.2ng/mL1390.090.030.27Cantonwine 2014
45518831AllPregnant women living in the Northern karst area of Puerto RicoPuerto RicoPRPROTECT (Puerto Rico Testsite for Exploring Contamination Threats)baseline; 4 weeks; 8 weeksUrine, spotLC-ID-MS/MS after enzymatic hydrolysisMono-carboxy-isononyl phthalate (cx-MiNP)ng/mLSpecific gravity1380.050.010.33Cantonwine 2014
86020400AllCouples seeking infertility evaluation and treatment at the Massachusetts General Hospital Fertility CenterUnited StatesUSbaseline; 35 days; 70 daysUrine, spotLC-ID-MS/MSMono-carboxy-isononyl phthalate (cx-MiNP)1.31.2ng/mL2690.220.140.34Meeker 2012
86720407AllCouples seeking infertility evaluation and treatment at the Massachusetts General Hospital Fertility CenterUnited StatesUSbaseline; 35 days; 70 daysUrine, spotLC-ID-MS/MS after enzymatic hydrolysisMono-carboxy-isononyl phthalate (cx-MiNP)2.52.5ng/mL2690.230.140.34Meeker 2012