Mono-oxo-isononyl phthalate (oxo-MiNP)

ID1492
NameMono-oxo-isononyl phthalate (oxo-MiNP)
SynonymsMono(oxo-isononyl) phthalate; Mono(oxo-isononyl) phthalates; MOiNP; MONP; 7-Oxo-MiNP; 7-Oxo-(mono-methyl-octyl) phthalate; Mono(4-methyl-7-oxo-octyl) phthalate; 7oxo-MMeOP
StructureThumb
DescriptionMetabolite of mono-isononyl phthalate (MiNP); secondary metabolite of di-isononyl phthalate (DiNP). Structure for 4-methyl-7-oxo- is represented.
GroupPhthalates
Sub-groupPhthalate monoesters
Exposure sourcePollution
UsePlasticizers
CAS number
PubChem ID
ChEBI ID
FooDB ID
HMDB ID

Biomarker measurements

Biomarker concentration values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed asPublication
18740187431AllParticipants in a study of reproductive healthDenmarkDKbaseline; 40 days; 83 daysUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)33100.00.260.952.744.236.8317.4181.0ng/mL0.0 mg/LCrudeFrederiksen 2013
18756187591AllParticipants in a study of reproductive healthDenmarkDKbaseline; 4 daysUrine, spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)3398.00.00.271.482.554.7614.947.7ng/mL0.0 mg/LCrudeFrederiksen 2013
18770187731AllParticipants in a study of reproductive healthDenmarkDKbaseline; 40 days; 83 daysUrine, 24-hLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)33100.00.430.791.692.974.8918.661.9ng/mL0.0 mg/LCrudeFrederiksen 2013
192970AllChildrenGermanyDEGerES IV (German Environmental Survey IV)Urine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)5995.45.419.128.986.75.05.9ug/L0.0 mg/L0.0 mg/LCrudeBecker 2009
193600AllDemographically diverse group of U.S. adults of both sexesUnited StatesUSUrine, spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)12987.01.20.00.51.22.45.06.6ng/mL0.0 mg/L0.0 mg/LCrudeSilva 2006
193870AllPrimary school starters at the City of FrankfurtGermanyDEUrine, spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)11178.08.13.85.827.660.06.39.9ug/g8.1 ug/g3.8 ug/g5.8 ug/gDensityCreatinineKoch 2011
19459194611ChildrenMother-child pairs in rural and urban DenmarkDenmarkDKUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)1457.60.571.32.75.614.0419.0ug/g7.6 ug/g2.7 ug/gDensityCreatinineFrederiksen 2013
19476194781MothersMother-child pairs in rural and urban DenmarkDenmarkDKUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)1452.70.611.32.69.923.0ug/g2.7 ug/g1.3 ug/gDensityCreatinineFrederiksen 2013
19515195171ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)104100.05.74.96.6ug/g5.7 ug/gDensityCreatinineKasper-Sonnenberg 2012
19541195431MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)103100.03.02.53.5ug/g3.0 ug/gDensityCreatinineKasper-Sonnenberg 2012
195580AllPregnant women in two French regionsFranceFRELFE (Étude Longitudinale Francaise depuis l’Enfance)deliveryUrine, spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)2797.816.20.53.128.8123.3ug/g7.8 ug/g3.1 ug/gDensityCreatinineZeman 2013
196190AllPregnant womenNorwayNOMoBa (Norwegian Mother and Child Cohort)Urine, spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)1105.1ug/g5.1 ug/gDensityCreatinineYe 2009
196350AllPregnant womenNorwayNOMoBa (Norwegian Mother and Child Cohort)Urine, spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)1109.35ug/g9.4 ug/gDensityCreatinineYe 2009
197560MalesAdults from southern GermanyGermanyDEINES (Integrated Exposure Assessment Survey)baseline; 1 day; 2 days; 3 days; 4 days; 5 days; 6 days; 7 daysUrine, spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)233.61.11.62.65.97.317.9ug/g3.6 ug/g2.6 ug/gDensityCreatinineFromme 2007
197650FemalesAdults from southern GermanyGermanyDEINES (Integrated Exposure Assessment Survey)baseline; 1 day; 2 days; 3 days; 4 days; 5 days; 6 days; 7 daysUrine, spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)273.80.71.52.87.18.911.4ug/g3.8 ug/g2.8 ug/gDensityCreatinineFromme 2007
198030AllStudents from 1988-2003GermanyDEESB (German Environmental Specimen Bank)Urine, 24-hLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)6341.05.472.7ug/g1.0 ug/gDensityCreatinineWittassek 2007
200220MothersPregnant women and their childrenTaiwanTWpregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)1000.650.080.34262.00.440.98ug/g0.7 ug/g0.3 ug/gDensityCreatinineLin 2011
200650Children aged 5-6 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)5911.649.588.6115.6ug/g11.6 ug/g9.6 ug/gDensityCreatinineLin 2011
200760Children aged 2-3 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)302.869.221.316.2ug/g2.9 ug/g9.2 ug/gDensityCreatinineLin 2011
202020AllInfants from the Munich areaGermanyDEINES (Integrated Exposure Assessment Survey)baseline; 1 day; 2 days; 3 days; 4 days; 5 days; 6 daysUrine, spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)2552.02.81.38.749.0ug/L0.0 mg/L0.0 mg/LCrudeFromme 2013
203430AllPregnant women from RotterdamNetherlandsNLGeneration R studypregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)10096.02.53.71.22.25.1152.0ug/L0.0 mg/L0.0 mg/LCrudeYe 2008
203590AllPregnant women from RotterdamNetherlandsNLGeneration R studypregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)1003.93.21.93.45.9119.0ug/g3.9 ug/g3.4 ug/gDensityCreatinineYe 2008

Intake values

No data available

Correlation values

No data available

Reproducibility values

IDMst. IDSubject groupPopulationCountryCountry codeCohortTime definitionBiological specimenExperimental methodBiomarkerBiomarker detailArithmetic meanGeometric meanMedianUnitAdjusted onReproducibility sizeICCICC 95% CI lowerICC 95% CI upperCV% WSCV% BSVAR WSVAR BSPublication
80919743AllAdults from southern GermanyGermanyDEINES (Integrated Exposure Assessment Survey)baseline; 1 day; 2 days; 3 days; 4 days; 5 days; 6 days; 7 daysUrine, spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)ug/gCreatinine500.37Fromme 2007