DHA (cis-22:6n-3)

ID184
NameDHA (cis-22:6n-3)
Synonymsall-cis-4,7,10,13,16,19-Docosahexaenoic acid
StructureThumb
Description
GroupFatty acids
Sub-groupPUFA
Exposure sourceDiet
Use
CAS number6217-54-5
PubChem ID445580
ChEBI ID28125
FooDB IDFDB003003
HMDB IDHMDB02183

Biomarker measurements

Biomarker concentration values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed asPublication
128812853AllMiddle-aged subjects in Southern ChinaChinaCNStudy on soyfood intake and cardiovascular risk factors in GuangzhouRed blood cell membrane, unspecifiedGC-FIDDHA (cis-22:6n-3)1259.7142.884percentRoot9.7 percentRootCrudeZhang 2010
12930DepressedDepressed and non-depressed participants in mood disorders studies in New York City areaUnited StatesUSPlasma, fasting and non-fastingGC-FIDDHA (cis-22:6n-3)3448.220.3mg/L48.2 mg/LCrudeSublette 2011
12990Non-depressedDepressed and non-depressed participants in mood disorders studies in New York City areaUnited StatesUSPlasma, fasting and non-fastingGC-FIDDHA (cis-22:6n-3)2762.223.0mg/L62.2 mg/LCrudeSublette 2011
13050All [by diagnosis]Depressed and non-depressed participants in mood disorders studies in New York City areaUnited StatesUSPlasma, fasting and non-fastingGC-FIDDHA (cis-22:6n-3)6154.422.519.251.4111.6mg/L54.4 mg/L51.4 mg/LCrudeSublette 2011
158115792MalesProfessional fishermen and their familiesFinlandFIFishermen studySerum, fastingGC-FIDDHA (cis-22:6n-3)1253.9percentRoot3.9 percentRootRegressionAgeTurunen 2010
160015982FemalesProfessional fishermen and their familiesFinlandFIFishermen studySerum, fastingGC-FIDDHA (cis-22:6n-3)1394.4percentRoot4.4 percentRootRegressionAgeTurunen 2010
160816062MalesSubjects with data on fish consumptionFinlandFIHealth 2000Serum, fastingGC-FIDDHA (cis-22:6n-3)5772.2percentRoot2.2 percentRootRegressionAgeTurunen 2010
161616142FemalesSubjects with data on fish consumptionFinlandFIHealth 2000Serum, fastingGC-FIDDHA (cis-22:6n-3)7122.2percentRoot2.2 percentRootRegressionAgeTurunen 2010
164316443AllNunavik Inuit adultsCanadaCANunavik Inuit Health SurveyRed blood cell membrane, fastingGC-FIDDHA (cis-22:6n-3)6275.37percentRoot5.4 percentRootCrudeLucas 2010
197819802AllNear-term pregnant womenCanadaCARed blood cell membrane (Phosphatidylcholine), fastingGC-FIDDHA (cis-22:6n-3)1052.110.78percentRoot2.1 percentRootCrudeFriesen 2010
199519972AllNear-term pregnant womenCanadaCARed blood cell membrane (Ethanolamine phosphoglyceride), fastingGC-FIDDHA (cis-22:6n-3)1057.471.97percentRoot7.5 percentRootCrudeFriesen 2010
216521662Children - MalesStudents in Shunan CityJapanJPShunan Child Cohort StudyRed blood cell membrane, fasting and non-fastingGC-FIDDHA (cis-22:6n-3)1066.82percentRoot6.8 percentRootCrudeOkuda 2009
219121922Children - FemalesStudents in Shunan CityJapanJPShunan Child Cohort StudyRed blood cell membrane, fasting and non-fastingGC-FIDDHA (cis-22:6n-3)856.86percentRoot6.9 percentRootCrudeOkuda 2009
221722182Adolescents - MalesStudents in Shunan CityJapanJPShunan Child Cohort StudyRed blood cell membrane, fasting and non-fastingGC-FIDDHA (cis-22:6n-3)916.52percentRoot6.5 percentRootCrudeOkuda 2009
224322442Adolescents - FemalesStudents in Shunan CityJapanJPShunan Child Cohort StudyRed blood cell membrane, fasting and non-fastingGC-FIDDHA (cis-22:6n-3)756.55percentRoot6.6 percentRootCrudeOkuda 2009
246899151Adults in Northern SwedenAdults in Northern SwedenSwedenSEVIP cohort (Vasterbotten Intervention Project)Red blood cell membrane, fastingGC-FIDDHA (cis-22:6n-3)885.35.15.5percentRoot5.3 percentRootCrudeWennberg 2009
246999161Adults in Northern SwedenAdults in Northern SwedenSwedenSEVIP cohort (Vasterbotten Intervention Project)Red blood cell membrane, fastingGC-FIDDHA (cis-22:6n-3)925.75.55.9percentRoot5.7 percentRootCrudeWennberg 2009
270127482AllElderly subjects with mild-to-moderate cognitive impairment or dementiaUnited StatesUSNAME (Nutrition, Aging, and Memory in Elders)Plasma, fastingGC-FIDDHA (cis-22:6n-3)2733.091.17percentRoot3.1 percentRootCrudeArsenault 2009
270927492High cognitive functionElderly subjects with mild-to-moderate cognitive impairment or dementiaUnited StatesUSNAME (Nutrition, Aging, and Memory in Elders)Plasma, fastingGC-FIDDHA (cis-22:6n-3)1863.061.13percentRoot3.1 percentRootCrudeArsenault 2009
271727502Low cognitive functionElderly subjects with mild-to-moderate cognitive impairment or dementiaUnited StatesUSNAME (Nutrition, Aging, and Memory in Elders)Plasma, fastingGC-FIDDHA (cis-22:6n-3)873.061.13percentRoot3.1 percentRootCrudeArsenault 2009
272527512No cognitive impairmentElderly subjects with mild-to-moderate cognitive impairment or dementiaUnited StatesUSNAME (Nutrition, Aging, and Memory in Elders)Plasma, fastingGC-FIDDHA (cis-22:6n-3)1293.031.19percentRoot3.0 percentRootCrudeArsenault 2009
273327522Mild cognitive impairmentElderly subjects with mild-to-moderate cognitive impairment or dementiaUnited StatesUSNAME (Nutrition, Aging, and Memory in Elders)Plasma, fastingGC-FIDDHA (cis-22:6n-3)823.151.2percentRoot3.2 percentRootCrudeArsenault 2009
274127532DementiaElderly subjects with mild-to-moderate cognitive impairment or dementiaUnited StatesUSNAME (Nutrition, Aging, and Memory in Elders)Plasma, fastingGC-FIDDHA (cis-22:6n-3)623.151.11percentRoot3.2 percentRootCrudeArsenault 2009
285928603AllControls in a coronary heart disease substudyUnited StatesUSNHS (Nurses' Health Study)Plasma, fasting and non-fastingGC-FIDDHA (cis-22:6n-3)3061.560.6percentRoot1.6 percentRootCrudeSun 2007
288328843AllControls in a coronary heart disease substudyUnited StatesUSNHS (Nurses' Health Study)Red blood cell, fasting and non-fastingGC-FIDDHA (cis-22:6n-3)3063.711.09percentRoot3.7 percentRootCrudeSun 2007
3023101571MalesMiddle-aged participants in a nested case-control studyFranceFRSU.VI.MAX (SUpplementation en VItamines et Mineraux AntioXydants)Plasma, fastingGC-FIDDHA (cis-22:6n-3)2762.490.81percentRoot2.5 percentRootCrudeAstorg 2008
3050101581FemalesMiddle-aged participants in a nested case-control studyFranceFRSU.VI.MAX (SUpplementation en VItamines et Mineraux AntioXydants)Plasma, fastingGC-FIDDHA (cis-22:6n-3)2572.650.84percentRoot2.7 percentRootCrudeAstorg 2008
316631603AllParticipants in a dietary validation studyAustraliaAUNambour Skin Cancer StudyPlasma, non-fastingGC-FIDDHA (cis-22:6n-3)4350.6715.4948.85ug/mL50.7 mg/L48.9 mg/LCrudeMcNaughton 2007
3317102241AllVolunteers from the Perth metropolitan areaAustraliaAURed blood cell membrane, fastingGC-FIDDHA (cis-22:6n-3)915.281.25.17percentRoot5.3 percentRoot5.2 percentRootCrudeMina 2007
337633683MalesParticipants in a case-cohort studyAustraliaAUMCCS (Melbourne Collaborative Cohort Study)Plasma, fasting and non-fastingGC-FIDDHA (cis-22:6n-3)20484.01.1percentRoot4.0 percentRootCrudeHodge 2007
341834103FemalesParticipants in a case-cohort studyAustraliaAUMCCS (Melbourne Collaborative Cohort Study)Plasma, fasting and non-fastingGC-FIDDHA (cis-22:6n-3)23914.11.1percentRoot4.1 percentRootCrudeHodge 2007
360399511All [by gender]Yup'ik Eskimos in southwest AlaskaUnited StatesUSCANHR I (Center for Alaska Native Health Research I)Red blood cell membrane, unspecifiedGC-FIDDHA (cis-22:6n-3)2216.01.91.69.5percentRoot6.0 percentRootCrudeO'Brien 2009
360699521MalesYup'ik Eskimos in southwest AlaskaUnited StatesUSCANHR I (Center for Alaska Native Health Research I)Red blood cell membrane, unspecifiedGC-FIDDHA (cis-22:6n-3)975.61.81.69.2percentRoot5.6 percentRootCrudeO'Brien 2009
360999531FemalesYup'ik Eskimos in southwest AlaskaUnited StatesUSCANHR I (Center for Alaska Native Health Research I)Red blood cell membrane, unspecifiedGC-FIDDHA (cis-22:6n-3)1246.31.92.19.5percentRoot6.3 percentRootCrudeO'Brien 2009
367036672AllStaff and students from the University of WollongongAustraliaAURed blood cell membrane, fastingGC-FIDDHA (cis-22:6n-3)534.061.12percentRoot4.1 percentRootCrudeSullivan 2006
367436712AllStaff and students from the University of WollongongAustraliaAUPlasma, fastingGC-FIDDHA (cis-22:6n-3)532.020.71percentRoot2.0 percentRootCrudeSullivan 2006
422442284Meat high consumers (Meat intake: >285 g/day)Men with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsPlasma, fastingGC-FIDDHA (cis-22:6n-3)183.41.0mg/100 mL34.0 mg/LCrudeMann 2006
424242464Meat moderate consumers (Meat intake: <260 g/day)Men with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsPlasma, fastingGC-FIDDHA (cis-22:6n-3)603.30.8mg/100 mL33.0 mg/LCrudeMann 2006
426042644Ovolacto-vegetariansMen with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsPlasma, fastingGC-FIDDHA (cis-22:6n-3)432.20.7mg/100 mL22.0 mg/LCrudeMann 2006
427842824VegansMen with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsPlasma, fastingGC-FIDDHA (cis-22:6n-3)182.00.4mg/100 mL20.0 mg/LCrudeMann 2006
437599401Margarine consumersVolunteers from the Dunedin areaNew ZealandNZPlasma, fastingGC-FIDDHA (cis-22:6n-3)652.3380.628percentRoot2.3 percentRootCrudeSkeaff 2006
439199391Butter consumersVolunteers from the Dunedin areaNew ZealandNZPlasma, fastingGC-FIDDHA (cis-22:6n-3)642.3590.571percentRoot2.4 percentRootCrudeSkeaff 2006
4448102291MalesControls in nested case-control studies on fatty acids and cancer risksJapanJPJACC Study (Japan Collaborative Cohort Study)Plasma, non-fastingGC-FIDDHA (cis-22:6n-3)6315.074.955.19percentRoot5.1 percentRootCrudeWakai 2005
4451102301FemalesControls in nested case-control studies on fatty acids and cancer risksJapanJPJACC Study (Japan Collaborative Cohort Study)Plasma, non-fastingGC-FIDDHA (cis-22:6n-3)6264.934.815.04percentRoot4.9 percentRootCrudeWakai 2005
451645173AllControls in a case-control study on diet and heart diseaseCosta RicaCRAdipose tissue, buttocksGC-FIDDHA (cis-22:6n-3)2000.140.05percentRoot0.1 percentRootCrudeBaylin 2005
455545563AllControls in a case-control study on diet and heart diseaseCosta RicaCRPlasma, fastingGC-FIDDHA (cis-22:6n-3)2001.490.38percentRoot1.5 percentRootCrudeBaylin 2005
459445953AllControls in a case-control study on diet and heart diseaseCosta RicaCRWhole blood, fastingGC-FIDDHA (cis-22:6n-3)2002.390.55percentRoot2.4 percentRootCrudeBaylin 2005
488448813MalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Plasma, fastingGC-FIDDHA (cis-22:6n-3)150.420.11mmol/L420000.0 nmol/LCrudeKuriki 2003
491849153FemalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Plasma, fastingGC-FIDDHA (cis-22:6n-3)790.490.13mmol/L490000.0 nmol/LCrudeKuriki 2003
495149483MalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Plasma, fastingGC-FIDDHA (cis-22:6n-3)154.050.99percentRoot4.1 percentRootCrudeKuriki 2003
498349803FemalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Plasma, fastingGC-FIDDHA (cis-22:6n-3)794.60.83percentRoot4.6 percentRootCrudeKuriki 2003
548254772AllControls in a case-control study on diet and heart diseaseCosta RicaCRAdipose tissue, buttocksGC-FIDDHA (cis-22:6n-3)5030.170.06percentRoot0.2 percentRootCrudeBaylin 2002
565156522AllPregnant womenMexicoMXA study on PUFAs and foetal neurodevelopmentRed blood cell membrane, unspecifiedGC-FIDDHA (cis-22:6n-3)356.0590.8524.8428.085percentRoot6.1 percentRootCrudeParra 2002
5718101621AllFemale university studentsGermanyDEPlasma (phospholipids), fastingGC-FIDDHA (cis-22:6n-3)524.661.132.863.513.854.395.446.27.78percentRoot4.7 percentRoot4.4 percentRootCrudeFremann 2002
5729101631AllFemale university studentsGermanyDEPlasma (triglycerides), fastingGC-FIDDHA (cis-22:6n-3)520.660.310.130.310.480.660.861.021.88percentRoot0.7 percentRoot0.7 percentRootCrudeFremann 2002
596559632Quartile 1 (Fish intake: <31 g/day)Adults from GipuzkoaSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Serum (fatty acids), fastingGC-FIDDHA (cis-22:6n-3)263.471.454.71nmol/L3.5 nmol/LCrudeAmiano 2001
596859662Quartile 2 (Fish intake: 32 to 64 g/day)Adults from GipuzkoaSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Serum (fatty acids), fastingGC-FIDDHA (cis-22:6n-3)243.912.325.74nmol/L3.9 nmol/LCrudeAmiano 2001
597159692Quartile 3 (Fish intake: 65 to 115 g/day)Adults from GipuzkoaSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Serum (fatty acids), fastingGC-FIDDHA (cis-22:6n-3)274.142.526.42nmol/L4.1 nmol/LCrudeAmiano 2001
597459722Quartile 4 (Fish intake: >115 g/day)Adults from GipuzkoaSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Serum (fatty acids), fastingGC-FIDDHA (cis-22:6n-3)254.612.656.63nmol/L4.6 nmol/LCrudeAmiano 2001
597759752Quartile 1 (Fish intake: <31 g/day)Adults from GipuzkoaSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Serum (LDL fraction phospholipids), fastingGC-FIDDHA (cis-22:6n-3)264.75percentRoot4.8 percentRootCrudeAmiano 2001
598059782Quartile 2 (Fish intake: 32 to 64 g/day)Adults from GipuzkoaSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Serum (LDL fraction phospholipids), fastingGC-FIDDHA (cis-22:6n-3)245.17percentRoot5.2 percentRootCrudeAmiano 2001
598359812Quartile 3 (Fish intake: 65 to 115 g/day)Adults from GipuzkoaSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Serum (LDL fraction phospholipids), fastingGC-FIDDHA (cis-22:6n-3)275.44percentRoot5.4 percentRootCrudeAmiano 2001
598659842Quartile 4 (Fish intake: >115 g/day)Adults from GipuzkoaSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Serum (LDL fraction phospholipids), fastingGC-FIDDHA (cis-22:6n-3)256.15percentRoot6.2 percentRootCrudeAmiano 2001
598959872Quartile 1 (Fish intake: <31 g/day)Adults from GipuzkoaSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Serum (LDL fraction cholesteryl esters), fastingGC-FIDDHA (cis-22:6n-3)261.23percentRoot1.2 percentRootCrudeAmiano 2001
599259902Quartile 2 (Fish intake: 32 to 64 g/day)Adults from GipuzkoaSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Serum (LDL fraction cholesteryl esters), fastingGC-FIDDHA (cis-22:6n-3)241.34percentRoot1.3 percentRootCrudeAmiano 2001
599559932Quartile 3 (Fish intake: 65 to 115 g/day)Adults from GipuzkoaSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Serum (LDL fraction cholesteryl esters), fastingGC-FIDDHA (cis-22:6n-3)271.39percentRoot1.4 percentRootCrudeAmiano 2001
599859962Quartile 4 (Fish intake: >115 g/day)Adults from GipuzkoaSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Serum (LDL fraction cholesteryl esters), fastingGC-FIDDHA (cis-22:6n-3)251.56percentRoot1.6 percentRootCrudeAmiano 2001
632963463AllObese patients in a clinic from MurciaSpainESAdipose tissue, periumbilical (subcutaneous)GC-FIDDHA (cis-22:6n-3)760.270.44percentRoot0.3 percentRootCrudeGaraulet 2001
635463713AllObese patients in a clinic from MurciaSpainESAdipose tissue, intraabdominal (perivisceral)GC-FIDDHA (cis-22:6n-3)570.350.32percentRoot0.4 percentRootCrudeGaraulet 2001
637963963AllObese patients in a clinic from MurciaSpainESAdipose tissue, intraabdominal (omental)GC-FIDDHA (cis-22:6n-3)240.250.25percentRoot0.3 percentRootCrudeGaraulet 2001
663666323AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDDHA (cis-22:6n-3)877.34.111.3percentRoot7.3 percentRootCrudeKobayashi 2001
665066463AllMiddle-aged menJapanJPJPHC Study Cohort IwinterSerum, fastingGC-FIDDHA (cis-22:6n-3)877.21.96.9percentRoot7.2 percentRoot6.9 percentRootCrudeKobayashi 2001
666466603AllMiddle-aged menJapanJPJPHC Study Cohort IsummerSerum, fastingGC-FIDDHA (cis-22:6n-3)877.41.97.2percentRoot7.4 percentRoot7.2 percentRootCrudeKobayashi 2001
7484100421AllMen in Uppsala county participant in a prospective survey on risk factors for ischemic heart diseaseSwedenSESerum (cholesterol esters), unspecifiedGC-FIDDHA (cis-22:6n-3)580.990.230.411.55percentRoot1.0 percentRootCrudeSmedman 1999
7497100431AllMen in Uppsala county participant in a prospective survey on risk factors for ischemic heart diseaseSwedenSESerum (phospholipids), unspecifiedGC-FIDDHA (cis-22:6n-3)664.891.132.297.02percentRoot4.9 percentRootCrudeSmedman 1999
765576482AllMen from Oerland military flight stationNorwayNOAdipose tissue, buttocksGC-FIDDHA (cis-22:6n-3)1190.190.240.35percentRoot0.2 percentRootCrudeAndersen 1999
766676592AllMen from Oerland military flight stationNorwayNOSerum, fastingGC-FIDDHA (cis-22:6n-3)1352.292.913.84percentRoot2.9 percentRootCrudeAndersen 1999
802280262AllMiddle-aged women in the Trondheim areaNorwayNOParticipants in a cardiovascular screening by SHUS (National Health Screening Service)Serum, non-fastingGC-FIDDHA (cis-22:6n-3)2346.921.83percentRoot6.9 percentRootCrudeHjartaker 1997
804980532AllMiddle-aged women in the Trondheim areaNorwayNOParticipants in a cardiovascular screening by SHUS (National Health Screening Service)Serum, non-fastingGC-FIDDHA (cis-22:6n-3)23483.8524.69mg/L83.9 mg/LCrudeHjartaker 1997
849684933AllControls from a dietary intervention trialDenmarkDKAdipose tissue, buttocksGC-FIDDHA (cis-22:6n-3)240.210.070.110.46percentRoot0.2 percentRootCrudeMarckmann 1995
856585592MalesMiddle-aged subjectsUnited StatesUSARIC (Atherosclerosis Risk in Communities)Plasma (cholesterol esters), fastingGC-FIDDHA (cis-22:6n-3)17120.430.15percentRoot0.4 percentRootCrudeMa 1995
857485682MalesMiddle-aged subjectsUnited StatesUSARIC (Atherosclerosis Risk in Communities)Plasma (phospholipids), fastingGC-FIDDHA (cis-22:6n-3)17122.730.85percentRoot2.7 percentRootCrudeMa 1995
858385772FemalesMiddle-aged subjectsUnited StatesUSARIC (Atherosclerosis Risk in Communities)Plasma (cholesterol esters), fastingGC-FIDDHA (cis-22:6n-3)18580.450.16percentRoot0.5 percentRootCrudeMa 1995
859285862FemalesMiddle-aged subjectsUnited StatesUSARIC (Atherosclerosis Risk in Communities)Plasma (phospholipids), fastingGC-FIDDHA (cis-22:6n-3)18582.850.85percentRoot2.9 percentRootCrudeMa 1995
867786802All [by gender]Obese subjects with non-insulin-dependent diabetes mellitusNetherlandsNLProspective study on weight lossbaseline; 1 year; 2 yearsAdipose tissue (triglycerides), abdomenGC-FIDDHA (cis-22:6n-3)530.30.14percentRoot0.3 percentRootCrudePopp-Snijders 1995
869586982MalesObese subjects with non-insulin-dependent diabetes mellitusNetherlandsNLProspective study on weight lossbaseline; 1 year; 2 yearsAdipose tissue (triglycerides), abdomenGC-FIDDHA (cis-22:6n-3)190.250.1percentRoot0.3 percentRootCrudePopp-Snijders 1995
871387162FemalesObese subjects with non-insulin-dependent diabetes mellitusNetherlandsNLProspective study on weight lossbaseline; 1 year; 2 yearsAdipose tissue (triglycerides), abdomenGC-FIDDHA (cis-22:6n-3)340.310.16percentRoot0.3 percentRootCrudePopp-Snijders 1995
896490502MalesAdults living in CopenhagenDenmarkDKAdipose tissue, buttocksGC-FIDDHA (cis-22:6n-3)230.250.08percentRoot0.3 percentRootCrudeTjonneland 1993
899490532FemalesAdults living in CopenhagenDenmarkDKAdipose tissue, buttocksGC-FIDDHA (cis-22:6n-3)630.310.1percentRoot0.3 percentRootCrudeTjonneland 1993
1014893543AllControls in a study on diet and breast cancer in Boston areaUnited StatesUSAdipose tissue, buttocksGC-FIDDHA (cis-22:6n-3)1150.190.090.020.54percentRoot0.2 percentRootCrudeLondon 1991
18613186143AllWomenUnited StatesUSNYUWHS (New York University Women's Health Study)baselinePlasma, non-fastingGC-FIDDHA (cis-22:6n-3)463.921.28percentRoot3.9 percentRootUnspecifiedZeleniuch-Jacquotte 2000

Intake values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionIntake toolIntake food coverageIntake time coverageIntake assessmentCompoundCompound detailSupplement intakes included?Measurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed asPublication
127212693AllMiddle-aged subjects in Southern ChinaChinaCNStudy on soyfood intake and cardiovascular risk factors in GuangzhouFood Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)1250.0240.024g/day23.7 mg/dayCrudeZhang 2010
128012773AllMiddle-aged subjects in Southern ChinaChinaCNStudy on soyfood intake and cardiovascular risk factors in GuangzhouDietary record (3-day)DHA (cis-22:6n-3)1250.040.028g/day39.4 mg/dayCrudeZhang 2010
12900DepressedDepressed and non-depressed participants in mood disorders studies in New York City areaUnited StatesUSFood Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)No3445.474.3mg/day45.4 mg/dayCrudeSublette 2011
12960Non-depressedDepressed and non-depressed participants in mood disorders studies in New York City areaUnited StatesUSFood Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)No2755.367.6mg/day55.3 mg/dayCrudeSublette 2011
13020All [by diagnosis]Depressed and non-depressed participants in mood disorders studies in New York City areaUnited StatesUSFood Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)No6149.871.00.017.0318.2mg/day49.8 mg/day17.0 mg/dayCrudeSublette 2011
196119602AllNear-term pregnant womenCanadaCAFood Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)No105146.0161.010.0100.0390.0mg/day146.0 mg/day100.0 mg/dayCrudeFriesen 2010
214821491Children - MalesStudents in Shunan CityJapanJPShunan Child Cohort StudyDiet History Questionnaire (DHQ)DHA (cis-22:6n-3)116187.6mg/1000 kcal187.6 mg/1000 kcalDensityEnergyOkuda 2009
217421751Children - FemalesStudents in Shunan CityJapanJPShunan Child Cohort StudyDiet History Questionnaire (DHQ)DHA (cis-22:6n-3)100196.8mg/1000 kcal196.8 mg/1000 kcalDensityEnergyOkuda 2009
220022011Adolescents - MalesStudents in Shunan CityJapanJPShunan Child Cohort StudyDiet History Questionnaire (DHQ)DHA (cis-22:6n-3)98206.4mg/1000 kcal206.4 mg/1000 kcalDensityEnergyOkuda 2009
222622271Adolescents - FemalesStudents in Shunan CityJapanJPShunan Child Cohort StudyDiet History Questionnaire (DHQ)DHA (cis-22:6n-3)84202.7mg/1000 kcal202.7 mg/1000 kcalDensityEnergyOkuda 2009
243699111Adults in Northern SwedenAdults in Northern SwedenSwedenSEVIP cohort (Vasterbotten Intervention Project)Food Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)880.21percentRoot0.2 percentRootCrudeWennberg 2009
243799121Adults in Northern SwedenAdults in Northern SwedenSwedenSEVIP cohort (Vasterbotten Intervention Project)Food Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)920.24percentRoot0.2 percentRootCrudeWennberg 2009
245299131Adults in Northern SwedenAdults in Northern SwedenSwedenSEVIP cohort (Vasterbotten Intervention Project)24-h Dietary recall (1-day)DHA (cis-22:6n-3)880.25percentRoot0.3 percentRootCrudeWennberg 2009
245399141Adults in Northern SwedenAdults in Northern SwedenSwedenSEVIP cohort (Vasterbotten Intervention Project)24-h Dietary recall (1-day)DHA (cis-22:6n-3)920.22percentRoot0.2 percentRootCrudeWennberg 2009
269527421AllElderly subjects with mild-to-moderate cognitive impairment or dementiaUnited StatesUSNAME (Nutrition, Aging, and Memory in Elders)Food Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)273206.0174.0mg/day206.0 mg/dayCrudeArsenault 2009
270327431High cognitive functionElderly subjects with mild-to-moderate cognitive impairment or dementiaUnited StatesUSNAME (Nutrition, Aging, and Memory in Elders)Food Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)186209.0182.0mg/day209.0 mg/dayCrudeArsenault 2009
271127441Low cognitive functionElderly subjects with mild-to-moderate cognitive impairment or dementiaUnited StatesUSNAME (Nutrition, Aging, and Memory in Elders)Food Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)87199.0157.0mg/day199.0 mg/dayCrudeArsenault 2009
271927451No cognitive impairmentElderly subjects with mild-to-moderate cognitive impairment or dementiaUnited StatesUSNAME (Nutrition, Aging, and Memory in Elders)Food Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)129211.0175.0mg/day211.0 mg/dayCrudeArsenault 2009
272727461Mild cognitive impairmentElderly subjects with mild-to-moderate cognitive impairment or dementiaUnited StatesUSNAME (Nutrition, Aging, and Memory in Elders)Food Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)82200.0185.0mg/day200.0 mg/dayCrudeArsenault 2009
273527471DementiaElderly subjects with mild-to-moderate cognitive impairment or dementiaUnited StatesUSNAME (Nutrition, Aging, and Memory in Elders)Food Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)62203.0161.0mg/day203.0 mg/dayCrudeArsenault 2009
290729083AllControls in a coronary heart disease substudyUnited StatesUSNHS (Nurses' Health Study)Food Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)No3060.290.22percentRoot0.3 percentRootCrudeSun 2007
300330042MalesMiddle-aged participants in a nested case-control studyFranceFRSU.VI.MAX (SUpplementation en VItamines et Mineraux AntioXydants)Dietary record (1-day)DHA (cis-22:6n-3)2760.30.2g/day295.8 mg/dayCrudeAstorg 2008
301130122MalesMiddle-aged participants in a nested case-control studyFranceFRSU.VI.MAX (SUpplementation en VItamines et Mineraux AntioXydants)Dietary record (1-day)DHA (cis-22:6n-3)2760.110.07percentEnergy0.1 percentEnergyDensityEnergyAstorg 2008
303030312FemalesMiddle-aged participants in a nested case-control studyFranceFRSU.VI.MAX (SUpplementation en VItamines et Mineraux AntioXydants)Dietary record (1-day)DHA (cis-22:6n-3)2570.240.16g/day236.6 mg/dayCrudeAstorg 2008
303830392FemalesMiddle-aged participants in a nested case-control studyFranceFRSU.VI.MAX (SUpplementation en VItamines et Mineraux AntioXydants)Dietary record (1-day)DHA (cis-22:6n-3)2570.120.07percentEnergy0.1 percentEnergyDensityEnergyAstorg 2008
318131753AllParticipants in a dietary validation studyAustraliaAUNambour Skin Cancer StudyFood Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)430.120.120.09g/day118.3 mg/day88.7 mg/dayRegressionEnergyMcNaughton 2007
319631903AllParticipants in a dietary validation studyAustraliaAUNambour Skin Cancer StudyWeighed Dietary record (2-day)DHA (cis-22:6n-3)430.110.130.08g/day108.5 mg/day78.9 mg/dayRegressionEnergyMcNaughton 2007
334833393MalesParticipants in a case-cohort studyAustraliaAUMCCS (Melbourne Collaborative Cohort Study)Food Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)20480.110.150.21g/day147.9 mg/dayCrudeHodge 2007
336233543MalesParticipants in a case-cohort studyAustraliaAUMCCS (Melbourne Collaborative Cohort Study)Food Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)20480.130.170.26percentRoot0.2 percentRootCrudeHodge 2007
339033823FemalesParticipants in a case-cohort studyAustraliaAUMCCS (Melbourne Collaborative Cohort Study)Food Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)23910.10.140.21g/day138.0 mg/dayCrudeHodge 2007
340433963FemalesParticipants in a case-cohort studyAustraliaAUMCCS (Melbourne Collaborative Cohort Study)Food Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)23910.130.20.31percentRoot0.2 percentRootCrudeHodge 2007
366636631AllStaff and students from the University of WollongongAustraliaAUFood Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)53134.0120.0108.0mg/day134.0 mg/day108.0 mg/dayCrudeSullivan 2006
415741614Meat high consumers (Meat intake: >285 g/day)Men with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsFood Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)160.120.1g/day118.3 mg/dayCrudeMann 2006
417341774Meat moderate consumers (Meat intake: <260 g/day)Men with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsFood Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)530.070.1g/day69.0 mg/dayCrudeMann 2006
418941944Ovolacto-vegetariansMen with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsFood Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)400.010.01g/day9.9 mg/dayCrudeMann 2006
420642104VegansMen with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsFood Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)170.00.0g/day0.0 mg/dayCrudeMann 2006
447744783AllControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)2000.210.21percentRoot0.2 percentRootRegressionEnergy ?Baylin 2005
486748643MalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Weighed Dietary record (7-day)DHA (cis-22:6n-3)No15626.0299.0mg/day626.0 mg/dayCrudeKuriki 2003
490148983FemalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Weighed Dietary record (7-day)DHA (cis-22:6n-3)No79571.0247.0mg/day571.0 mg/dayCrudeKuriki 2003
493549323MalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Weighed Dietary record (7-day)DHA (cis-22:6n-3)No151.280.63percentRoot1.3 percentRootCrudeKuriki 2003
496749643FemalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Weighed Dietary record (7-day)DHA (cis-22:6n-3)No791.260.53percentRoot1.3 percentRootCrudeKuriki 2003
552355182AllControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)5030.180.16percentRoot0.2 percentRootCrudeBaylin 2002
556055562AllControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)5030.130.12g/day128.2 mg/dayRegressionEnergyBaylin 2002
5632102382AllPregnant womenMexicoMXA study on PUFAs and foetal neurodevelopmentFood Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)1460.140.110.00.63mg/day0.1 mg/dayCrudeParra 2002
593759332Quartile 1 (Fish intake: <31 g/day)Adults from GipuzkoaSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Diet History Questionnaire (DHQ)DHA (cis-22:6n-3)260.190.15g/day187.3 mg/dayRegressionEnergyAmiano 2001
594559412Quartile 2 (Fish intake: 32 to 64 g/day)Adults from GipuzkoaSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Diet History Questionnaire (DHQ)DHA (cis-22:6n-3)240.440.22g/day433.8 mg/dayRegressionEnergyAmiano 2001
595359492Quartile 3 (Fish intake: 65 to 115 g/day)Adults from GipuzkoaSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Diet History Questionnaire (DHQ)DHA (cis-22:6n-3)270.580.41g/day571.9 mg/dayRegressionEnergyAmiano 2001
596159572Quartile 4 (Fish intake: >115 g/day)Adults from GipuzkoaSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Diet History Questionnaire (DHQ)DHA (cis-22:6n-3)250.850.44g/day838.1 mg/dayRegressionEnergyAmiano 2001
640464123AllObese patients in a clinic from MurciaSpainESDietary record (7-day)DHA (cis-22:6n-3)760.320.29percentRoot0.3 percentRootCrudeGaraulet 2001
660866043AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)DHA (cis-22:6n-3)No870.90.22.7g/day887.4 mg/dayCrudeKobayashi 2001
662266183AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)DHA (cis-22:6n-3)No871.70.53.5percentRoot1.7 percentRootCrudeKobayashi 2001
7634100961AllMen from Oerland military flight stationNorwayNOFood Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)Yes1350.160.460.75g/day453.5 mg/dayCrudeAndersen 1999
764576382AllMen from Oerland military flight stationNorwayNOFood Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)Yes1350.210.430.76percentRoot0.4 percentRootCrudeAndersen 1999
848884852AllControls from a dietary intervention trialDenmarkDKWeighed Dietary record (7-day)DHA (cis-22:6n-3)240.240.160.00.59g/day236.6 mg/dayCrudeMarckmann 1995
853085242MalesMiddle-aged subjectsUnited StatesUSARIC (Atherosclerosis Risk in Communities)Food Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)No17120.140.14g/day138.0 mg/dayCrudeMa 1995
853985332MalesMiddle-aged subjectsUnited StatesUSARIC (Atherosclerosis Risk in Communities)Food Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)No17120.230.26percentRoot0.2 percentRootCrudeMa 1995
854885422FemalesMiddle-aged subjectsUnited StatesUSARIC (Atherosclerosis Risk in Communities)Food Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)No18580.160.15g/day157.8 mg/dayCrudeMa 1995
855685512FemalesMiddle-aged subjectsUnited StatesUSARIC (Atherosclerosis Risk in Communities)Food Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)No18580.330.35percentRoot0.3 percentRootCrudeMa 1995
865686522MalesObese subjects with non-insulin-dependent diabetes mellitusNetherlandsNLProspective study on weight lossDietary record (3-day)DHA (cis-22:6n-3)190.250.22percentRoot0.3 percentRootCrudePopp-Snijders 1995
866386592FemalesObese subjects with non-insulin-dependent diabetes mellitusNetherlandsNLProspective study on weight lossDietary record (3-day)DHA (cis-22:6n-3)340.180.14percentRoot0.2 percentRootCrudePopp-Snijders 1995
900389993MalesAdults living in CopenhagenDenmarkDKWeighed Dietary record (7-day)DHA (cis-22:6n-3)230.290.27percentRoot0.3 percentRootCrudeTjonneland 1993
901290083FemalesAdults living in CopenhagenDenmarkDKWeighed Dietary record (7-day)DHA (cis-22:6n-3)630.370.28percentRoot0.4 percentRootCrudeTjonneland 1993
989498951AllMiddle-aged women in QuebecCanadaCARandomized clinical trial on ethyl-EPA supplementationFood Frequency Questionnaire (FFQ)DHA (cis-22:6n-3)65128.099.40.0105.0448.0mg/day128.0 mg/day105.0 mg/dayCrudeLucas 2009

Correlation values

Reproducibility values

IDMst. IDSubject groupPopulationCountryCountry codeCohortTime definitionBiological specimenExperimental methodBiomarkerBiomarker detailArithmetic meanGeometric meanMedianUnitAdjusted onReproducibility sizeICCICC 95% CI lowerICC 95% CI upperCV% WSCV% BSVAR WSVAR BSPublication
781731Mild cognitive impairmentElderly subjects with and without mild cognitive impairmentUnited StatesUSbaseline; 1 monthPlasma, fastingGC-FIDDHA (cis-22:6n-3)missing unit190.86Bowman 2011
561753No cognitive impairmentElderly subjects with and without mild cognitive impairmentUnited StatesUSbaseline; 1 monthPlasma, fastingGC-FIDDHA (cis-22:6n-3)missing unit190.97Bowman 2011
441775All [by diagnosis]Elderly subjects with and without mild cognitive impairmentUnited StatesUSbaseline; 1 monthPlasma, fastingGC-FIDDHA (cis-22:6n-3)missing unit380.92Bowman 2011
3326636AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDDHA (cis-22:6n-3)7.3percentRoot870.77Kobayashi 2001
9038677All [by gender]Obese subjects with non-insulin-dependent diabetes mellitusNetherlandsNLProspective study on weight lossbaseline; 1 year; 2 yearsAdipose tissue (triglycerides), abdomenGC-FIDDHA (cis-22:6n-3)0.3percentRoot5313.045.0Popp-Snijders 1995
27018586AllWomenUnited StatesUSNYUWHS (New York University Women's Health Study)baseline; 1 year; 2 yearsPlasma, non-fastingGC-FIDDHA (cis-22:6n-3)percentRoot460.660.530.79Zeleniuch-Jacquotte 2000