DPA (cis-22:5n-3)

ID215
NameDPA (cis-22:5n-3)
Synonymsall-cis-7,10,13,16,19-Docosapentaenoic acid
StructureThumb
Description
GroupFatty acids
Sub-groupPUFA
Exposure sourceDiet
Use
CAS number24880-45-3
PubChem ID5497182
ChEBI ID53488
FooDB IDFDB021831
HMDB IDHMDB06528

Biomarker measurements

Biomarker concentration values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed asPublication
158215792MalesProfessional fishermen and their familiesFinlandFIFishermen studySerum, fastingGC-FIDDPA (cis-22:5n-3)1250.68percentRoot0.7 percentRootRegressionAgeTurunen 2010
160115982FemalesProfessional fishermen and their familiesFinlandFIFishermen studySerum, fastingGC-FIDDPA (cis-22:5n-3)1390.62percentRoot0.6 percentRootRegressionAgeTurunen 2010
160916062MalesSubjects with data on fish consumptionFinlandFIHealth 2000Serum, fastingGC-FIDDPA (cis-22:5n-3)5770.5percentRoot0.5 percentRootRegressionAgeTurunen 2010
161716142FemalesSubjects with data on fish consumptionFinlandFIHealth 2000Serum, fastingGC-FIDDPA (cis-22:5n-3)7120.49percentRoot0.5 percentRootRegressionAgeTurunen 2010
164216443AllNunavik Inuit adultsCanadaCANunavik Inuit Health SurveyRed blood cell membrane, fastingGC-FIDDPA (cis-22:5n-3)6272.15percentRoot2.2 percentRootCrudeLucas 2010
197719802AllNear-term pregnant womenCanadaCARed blood cell membrane (Phosphatidylcholine), fastingGC-FIDDPA (cis-22:5n-3)1050.320.12percentRoot0.3 percentRootCrudeFriesen 2010
199419972AllNear-term pregnant womenCanadaCARed blood cell membrane (Ethanolamine phosphoglyceride), fastingGC-FIDDPA (cis-22:5n-3)1053.210.71percentRoot3.2 percentRootCrudeFriesen 2010
216421662Children - MalesStudents in Shunan CityJapanJPShunan Child Cohort StudyRed blood cell membrane, fasting and non-fastingGC-FIDDPA (cis-22:5n-3)1062.22percentRoot2.2 percentRootCrudeOkuda 2009
219021922Children - FemalesStudents in Shunan CityJapanJPShunan Child Cohort StudyRed blood cell membrane, fasting and non-fastingGC-FIDDPA (cis-22:5n-3)852.14percentRoot2.1 percentRootCrudeOkuda 2009
221622182Adolescents - MalesStudents in Shunan CityJapanJPShunan Child Cohort StudyRed blood cell membrane, fasting and non-fastingGC-FIDDPA (cis-22:5n-3)912.24percentRoot2.2 percentRootCrudeOkuda 2009
224222442Adolescents - FemalesStudents in Shunan CityJapanJPShunan Child Cohort StudyRed blood cell membrane, fasting and non-fastingGC-FIDDPA (cis-22:5n-3)752.2percentRoot2.2 percentRootCrudeOkuda 2009
270027482AllElderly subjects with mild-to-moderate cognitive impairment or dementiaUnited StatesUSNAME (Nutrition, Aging, and Memory in Elders)Plasma, fastingGC-FIDDPA (cis-22:5n-3)2730.770.2percentRoot0.8 percentRootCrudeArsenault 2009
270827492High cognitive functionElderly subjects with mild-to-moderate cognitive impairment or dementiaUnited StatesUSNAME (Nutrition, Aging, and Memory in Elders)Plasma, fastingGC-FIDDPA (cis-22:5n-3)1860.770.21percentRoot0.8 percentRootCrudeArsenault 2009
271627502Low cognitive functionElderly subjects with mild-to-moderate cognitive impairment or dementiaUnited StatesUSNAME (Nutrition, Aging, and Memory in Elders)Plasma, fastingGC-FIDDPA (cis-22:5n-3)870.770.21percentRoot0.8 percentRootCrudeArsenault 2009
272427512No cognitive impairmentElderly subjects with mild-to-moderate cognitive impairment or dementiaUnited StatesUSNAME (Nutrition, Aging, and Memory in Elders)Plasma, fastingGC-FIDDPA (cis-22:5n-3)1290.780.22percentRoot0.8 percentRootCrudeArsenault 2009
273227522Mild cognitive impairmentElderly subjects with mild-to-moderate cognitive impairment or dementiaUnited StatesUSNAME (Nutrition, Aging, and Memory in Elders)Plasma, fastingGC-FIDDPA (cis-22:5n-3)820.750.2percentRoot0.8 percentRootCrudeArsenault 2009
274027532DementiaElderly subjects with mild-to-moderate cognitive impairment or dementiaUnited StatesUSNAME (Nutrition, Aging, and Memory in Elders)Plasma, fastingGC-FIDDPA (cis-22:5n-3)620.790.15percentRoot0.8 percentRootCrudeArsenault 2009
285828603AllControls in a coronary heart disease substudyUnited StatesUSNHS (Nurses' Health Study)Plasma, fasting and non-fastingGC-FIDDPA (cis-22:5n-3)3060.440.09percentRoot0.4 percentRootCrudeSun 2007
288228843AllControls in a coronary heart disease substudyUnited StatesUSNHS (Nurses' Health Study)Red blood cell, fasting and non-fastingGC-FIDDPA (cis-22:5n-3)3061.850.28percentRoot1.9 percentRootCrudeSun 2007
3022101571MalesMiddle-aged participants in a nested case-control studyFranceFRSU.VI.MAX (SUpplementation en VItamines et Mineraux AntioXydants)Plasma, fastingGC-FIDDPA (cis-22:5n-3)2760.540.14percentRoot0.5 percentRootCrudeAstorg 2008
3049101581FemalesMiddle-aged participants in a nested case-control studyFranceFRSU.VI.MAX (SUpplementation en VItamines et Mineraux AntioXydants)Plasma, fastingGC-FIDDPA (cis-22:5n-3)2570.540.18percentRoot0.5 percentRootCrudeAstorg 2008
316531603AllParticipants in a dietary validation studyAustraliaAUNambour Skin Cancer StudyPlasma, non-fastingGC-FIDDPA (cis-22:5n-3)4315.134.2214.63ug/mL15.1 mg/L14.6 mg/LCrudeMcNaughton 2007
366936672AllStaff and students from the University of WollongongAustraliaAURed blood cell membrane, fastingGC-FIDDPA (cis-22:5n-3)532.080.41percentRoot2.1 percentRootCrudeSullivan 2006
367336712AllStaff and students from the University of WollongongAustraliaAUPlasma, fastingGC-FIDDPA (cis-22:5n-3)530.480.11percentRoot0.5 percentRootCrudeSullivan 2006
422342284Meat high consumers (Meat intake: >285 g/day)Men with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsPlasma, fastingGC-FIDDPA (cis-22:5n-3)181.30.2mg/100 mL13.0 mg/LCrudeMann 2006
424142464Meat moderate consumers (Meat intake: <260 g/day)Men with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsPlasma, fastingGC-FIDDPA (cis-22:5n-3)601.20.2mg/100 mL12.0 mg/LCrudeMann 2006
425942644Ovolacto-vegetariansMen with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsPlasma, fastingGC-FIDDPA (cis-22:5n-3)431.10.2mg/100 mL11.0 mg/LCrudeMann 2006
427742824VegansMen with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsPlasma, fastingGC-FIDDPA (cis-22:5n-3)181.00.3mg/100 mL10.0 mg/LCrudeMann 2006
437499401Margarine consumersVolunteers from the Dunedin areaNew ZealandNZPlasma, fastingGC-FIDDPA (cis-22:5n-3)650.8460.18percentRoot0.8 percentRootCrudeSkeaff 2006
439099391Butter consumersVolunteers from the Dunedin areaNew ZealandNZPlasma, fastingGC-FIDDPA (cis-22:5n-3)640.9730.175percentRoot1.0 percentRootCrudeSkeaff 2006
4447102291MalesControls in nested case-control studies on fatty acids and cancer risksJapanJPJACC Study (Japan Collaborative Cohort Study)Plasma, non-fastingGC-FIDDPA (cis-22:5n-3)6310.850.830.88percentRoot0.9 percentRootCrudeWakai 2005
4450102301FemalesControls in nested case-control studies on fatty acids and cancer risksJapanJPJACC Study (Japan Collaborative Cohort Study)Plasma, non-fastingGC-FIDDPA (cis-22:5n-3)6260.80.790.82percentRoot0.8 percentRootCrudeWakai 2005
451545173AllControls in a case-control study on diet and heart diseaseCosta RicaCRAdipose tissue, buttocksGC-FIDDPA (cis-22:5n-3)2000.190.05percentRoot0.2 percentRootCrudeBaylin 2005
455445563AllControls in a case-control study on diet and heart diseaseCosta RicaCRPlasma, fastingGC-FIDDPA (cis-22:5n-3)2000.410.12percentRoot0.4 percentRootCrudeBaylin 2005
459345953AllControls in a case-control study on diet and heart diseaseCosta RicaCRWhole blood, fastingGC-FIDDPA (cis-22:5n-3)2000.90.19percentRoot0.9 percentRootCrudeBaylin 2005
488348813MalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Plasma, fastingGC-FIDDPA (cis-22:5n-3)150.060.02mmol/L60000.0 nmol/LCrudeKuriki 2003
491749153FemalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Plasma, fastingGC-FIDDPA (cis-22:5n-3)790.060.02mmol/L60000.0 nmol/LCrudeKuriki 2003
495049483MalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Plasma, fastingGC-FIDDPA (cis-22:5n-3)150.620.19percentRoot0.6 percentRootCrudeKuriki 2003
498249803FemalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Plasma, fastingGC-FIDDPA (cis-22:5n-3)790.580.11percentRoot0.6 percentRootCrudeKuriki 2003
548154772AllControls in a case-control study on diet and heart diseaseCosta RicaCRAdipose tissue, buttocksGC-FIDDPA (cis-22:5n-3)5030.210.06percentRoot0.2 percentRootCrudeBaylin 2002
565056522AllPregnant womenMexicoMXA study on PUFAs and foetal neurodevelopmentRed blood cell membrane, unspecifiedGC-FIDDPA (cis-22:5n-3)353.7210.6351.0664.465percentRoot3.7 percentRootCrudeParra 2002
663566323AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDDPA (cis-22:5n-3)871.20.52.2percentRoot1.2 percentRootCrudeKobayashi 2001
664966463AllMiddle-aged menJapanJPJPHC Study Cohort IwinterSerum, fastingGC-FIDDPA (cis-22:5n-3)871.20.41.2percentRoot1.2 percentRoot1.2 percentRootCrudeKobayashi 2001
666366603AllMiddle-aged menJapanJPJPHC Study Cohort IsummerSerum, fastingGC-FIDDPA (cis-22:5n-3)871.20.41.2percentRoot1.2 percentRoot1.2 percentRootCrudeKobayashi 2001
765476482AllMen from Oerland military flight stationNorwayNOAdipose tissue, buttocksGC-FIDDPA (cis-22:5n-3)1190.180.240.29percentRoot0.2 percentRootCrudeAndersen 1999
766576592AllMen from Oerland military flight stationNorwayNOSerum, fastingGC-FIDDPA (cis-22:5n-3)1350.550.620.74percentRoot0.6 percentRootCrudeAndersen 1999
802180262AllMiddle-aged women in the Trondheim areaNorwayNOParticipants in a cardiovascular screening by SHUS (National Health Screening Service)Serum, non-fastingGC-FIDDPA (cis-22:5n-3)2341.330.24percentRoot1.3 percentRootCrudeHjartaker 1997
804880532AllMiddle-aged women in the Trondheim areaNorwayNOParticipants in a cardiovascular screening by SHUS (National Health Screening Service)Serum, non-fastingGC-FIDDPA (cis-22:5n-3)23416.173.72mg/L16.2 mg/LCrudeHjartaker 1997
849584933AllControls from a dietary intervention trialDenmarkDKAdipose tissue, buttocksGC-FIDDPA (cis-22:5n-3)240.20.050.130.35percentRoot0.2 percentRootCrudeMarckmann 1995
867686802All [by gender]Obese subjects with non-insulin-dependent diabetes mellitusNetherlandsNLProspective study on weight lossbaseline; 1 year; 2 yearsAdipose tissue (triglycerides), abdomenGC-FIDDPA (cis-22:5n-3)530.370.12percentRoot0.4 percentRootCrudePopp-Snijders 1995
869486982MalesObese subjects with non-insulin-dependent diabetes mellitusNetherlandsNLProspective study on weight lossbaseline; 1 year; 2 yearsAdipose tissue (triglycerides), abdomenGC-FIDDPA (cis-22:5n-3)190.320.08percentRoot0.3 percentRootCrudePopp-Snijders 1995
871287162FemalesObese subjects with non-insulin-dependent diabetes mellitusNetherlandsNLProspective study on weight lossbaseline; 1 year; 2 yearsAdipose tissue (triglycerides), abdomenGC-FIDDPA (cis-22:5n-3)340.410.12percentRoot0.4 percentRootCrudePopp-Snijders 1995
18612186143AllWomenUnited StatesUSNYUWHS (New York University Women's Health Study)baselinePlasma, non-fastingGC-FIDDPA (cis-22:5n-3)460.850.38percentRoot0.9 percentRootUnspecifiedZeleniuch-Jacquotte 2000

Intake values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionIntake toolIntake food coverageIntake time coverageIntake assessmentCompoundCompound detailSupplement intakes included?Measurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed asPublication
214721491Children - MalesStudents in Shunan CityJapanJPShunan Child Cohort StudyDiet History Questionnaire (DHQ)DPA (cis-22:5n-3)11636.0mg/1000 kcal36.0 mg/1000 kcalDensityEnergyOkuda 2009
217321751Children - FemalesStudents in Shunan CityJapanJPShunan Child Cohort StudyDiet History Questionnaire (DHQ)DPA (cis-22:5n-3)10037.6mg/1000 kcal37.6 mg/1000 kcalDensityEnergyOkuda 2009
219922011Adolescents - MalesStudents in Shunan CityJapanJPShunan Child Cohort StudyDiet History Questionnaire (DHQ)DPA (cis-22:5n-3)9837.2mg/1000 kcal37.2 mg/1000 kcalDensityEnergyOkuda 2009
222522271Adolescents - FemalesStudents in Shunan CityJapanJPShunan Child Cohort StudyDiet History Questionnaire (DHQ)DPA (cis-22:5n-3)8435.8mg/1000 kcal35.8 mg/1000 kcalDensityEnergyOkuda 2009
290629083AllControls in a coronary heart disease substudyUnited StatesUSNHS (Nurses' Health Study)Food Frequency Questionnaire (FFQ)DPA (cis-22:5n-3)No3060.040.03percentRoot0.0 percentRootCrudeSun 2007
300230042MalesMiddle-aged participants in a nested case-control studyFranceFRSU.VI.MAX (SUpplementation en VItamines et Mineraux AntioXydants)Dietary record (1-day)DPA (cis-22:5n-3)2760.080.03g/day78.9 mg/dayCrudeAstorg 2008
301030122MalesMiddle-aged participants in a nested case-control studyFranceFRSU.VI.MAX (SUpplementation en VItamines et Mineraux AntioXydants)Dietary record (1-day)DPA (cis-22:5n-3)2760.030.01percentEnergy0.0 percentEnergyDensityEnergyAstorg 2008
302930312FemalesMiddle-aged participants in a nested case-control studyFranceFRSU.VI.MAX (SUpplementation en VItamines et Mineraux AntioXydants)Dietary record (1-day)DPA (cis-22:5n-3)2570.060.03g/day59.2 mg/dayCrudeAstorg 2008
303730392FemalesMiddle-aged participants in a nested case-control studyFranceFRSU.VI.MAX (SUpplementation en VItamines et Mineraux AntioXydants)Dietary record (1-day)DPA (cis-22:5n-3)2570.030.01percentEnergy0.0 percentEnergyDensityEnergyAstorg 2008
318031753AllParticipants in a dietary validation studyAustraliaAUNambour Skin Cancer StudyFood Frequency Questionnaire (FFQ)DPA (cis-22:5n-3)430.040.020.03g/day39.4 mg/day29.6 mg/dayRegressionEnergyMcNaughton 2007
319531903AllParticipants in a dietary validation studyAustraliaAUNambour Skin Cancer StudyWeighed Dietary record (2-day)DPA (cis-22:5n-3)430.040.030.03g/day39.4 mg/day29.6 mg/dayRegressionEnergyMcNaughton 2007
366536631AllStaff and students from the University of WollongongAustraliaAUFood Frequency Questionnaire (FFQ)DPA (cis-22:5n-3)5352.041.048.0mg/day52.0 mg/day48.0 mg/dayCrudeSullivan 2006
415641614Meat high consumers (Meat intake: >285 g/day)Men with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsFood Frequency Questionnaire (FFQ)DPA (cis-22:5n-3)160.090.05g/day88.7 mg/dayCrudeMann 2006
417241774Meat moderate consumers (Meat intake: <260 g/day)Men with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsFood Frequency Questionnaire (FFQ)DPA (cis-22:5n-3)530.030.02g/day29.6 mg/dayCrudeMann 2006
418841944Ovolacto-vegetariansMen with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsFood Frequency Questionnaire (FFQ)DPA (cis-22:5n-3)400.00.01g/day0.0 mg/dayCrudeMann 2006
420542104VegansMen with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsFood Frequency Questionnaire (FFQ)DPA (cis-22:5n-3)170.00.0g/day0.0 mg/dayCrudeMann 2006
447644783AllControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)DPA (cis-22:5n-3)2000.070.04percentRoot0.1 percentRootRegressionEnergy ?Baylin 2005
486648643MalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Weighed Dietary record (7-day)DPA (cis-22:5n-3)No15106.060.0mg/day106.0 mg/dayCrudeKuriki 2003
490048983FemalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Weighed Dietary record (7-day)DPA (cis-22:5n-3)No7985.045.0mg/day85.0 mg/dayCrudeKuriki 2003
493449323MalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Weighed Dietary record (7-day)DPA (cis-22:5n-3)No150.210.12percentRoot0.2 percentRootCrudeKuriki 2003
496649643FemalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Weighed Dietary record (7-day)DPA (cis-22:5n-3)No790.190.1percentRoot0.2 percentRootCrudeKuriki 2003
552255182AllControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)DPA (cis-22:5n-3)5030.020.02percentRoot0.0 percentRootCrudeBaylin 2002
555955562AllControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)DPA (cis-22:5n-3)5030.020.01g/day19.7 mg/dayRegressionEnergyBaylin 2002
660766043AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)DPA (cis-22:5n-3)No870.10.00.4g/day98.6 mg/dayCrudeKobayashi 2001
662166183AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)DPA (cis-22:5n-3)No870.30.10.6percentRoot0.3 percentRootCrudeKobayashi 2001
7633100961AllMen from Oerland military flight stationNorwayNOFood Frequency Questionnaire (FFQ)DPA (cis-22:5n-3)Yes1350.040.070.11g/day69.0 mg/dayCrudeAndersen 1999
764476382AllMen from Oerland military flight stationNorwayNOFood Frequency Questionnaire (FFQ)DPA (cis-22:5n-3)Yes1350.050.070.11percentRoot0.1 percentRootCrudeAndersen 1999
848784852AllControls from a dietary intervention trialDenmarkDKWeighed Dietary record (7-day)DPA (cis-22:5n-3)240.070.050.00.15g/day69.0 mg/dayCrudeMarckmann 1995

Correlation values

Reproducibility values

IDMst. IDSubject groupPopulationCountryCountry codeCohortTime definitionBiological specimenExperimental methodBiomarkerBiomarker detailArithmetic meanGeometric meanMedianUnitAdjusted onReproducibility sizeICCICC 95% CI lowerICC 95% CI upperCV% WSCV% BSVAR WSVAR BSPublication
26918585AllWomenUnited StatesUSNYUWHS (New York University Women's Health Study)baseline; 1 year; 2 yearsPlasma, non-fastingGC-FIDDPA (cis-22:5n-3)percentRoot460.70.580.82Zeleniuch-Jacquotte 2000
3316635AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDDPA (cis-22:5n-3)1.2percentRoot870.83Kobayashi 2001