Dihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)

ID223
NameDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)
Synonymsall-cis-8,11,14-Eicosatrienoic acid
StructureThumb
Description
GroupFatty acids
Sub-groupPUFA
Exposure sourceDiet
Use
CAS number1783-84-2
PubChem ID5280581
ChEBI ID53486
FooDB IDFDB023082
HMDB IDHMDB02925

Biomarker measurements

Biomarker concentration values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed asPublication
163616342AllNunavik Inuit adultsCanadaCANunavik Inuit Health SurveyRed blood cell membrane, fastingGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)6271.75percentRoot1.8 percentRootCrudeLucas 2010
197119792AllNear-term pregnant womenCanadaCARed blood cell membrane (Phosphatidylcholine), fastingGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)1051.190.49percentRoot1.2 percentRootCrudeFriesen 2010
198819962AllNear-term pregnant womenCanadaCARed blood cell membrane (Ethanolamine phosphoglyceride), fastingGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)1050.970.64percentRoot1.0 percentRootCrudeFriesen 2010
3018101571MalesMiddle-aged participants in a nested case-control studyFranceFRSU.VI.MAX (SUpplementation en VItamines et Mineraux AntioXydants)Plasma, fastingGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)2761.540.32percentRoot1.5 percentRootCrudeAstorg 2008
3045101581FemalesMiddle-aged participants in a nested case-control studyFranceFRSU.VI.MAX (SUpplementation en VItamines et Mineraux AntioXydants)Plasma, fastingGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)2571.510.34percentRoot1.5 percentRootCrudeAstorg 2008
437099401Margarine consumersVolunteers from the Dunedin areaNew ZealandNZPlasma, fastingGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)652.6160.512percentRoot2.6 percentRootCrudeSkeaff 2006
438699391Butter consumersVolunteers from the Dunedin areaNew ZealandNZPlasma, fastingGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)642.5310.418percentRoot2.5 percentRootCrudeSkeaff 2006
452045233AllControls in a case-control study on diet and heart diseaseCosta RicaCRAdipose tissue, buttocksGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)2000.330.12percentRoot0.3 percentRootCrudeBaylin 2005
455945623AllControls in a case-control study on diet and heart diseaseCosta RicaCRPlasma, fastingGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)2001.680.38percentRoot1.7 percentRootCrudeBaylin 2005
459846013AllControls in a case-control study on diet and heart diseaseCosta RicaCRWhole blood, fastingGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)2001.750.37percentRoot1.8 percentRootCrudeBaylin 2005
547454702AllControls in a case-control study on diet and heart diseaseCosta RicaCRAdipose tissue, buttocksGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)4730.290.1percentRoot0.3 percentRootCrudeBaylin 2002
564356462AllPregnant womenMexicoMXA study on PUFAs and foetal neurodevelopmentRed blood cell membrane, unspecifiedGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)351.7540.5570.6753.091percentRoot1.8 percentRootCrudeParra 2002
5715101621AllFemale university studentsGermanyDEPlasma (phospholipids), fastingGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)520.010.010.00.00.00.010.010.140.25percentRoot0.0 percentRoot0.0 percentRootCrudeFremann 2002
5726101631AllFemale university studentsGermanyDEPlasma (triglycerides), fastingGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)520.380.180.050.180.250.370.490.660.89percentRoot0.4 percentRoot0.4 percentRootCrudeFremann 2002
633363473AllObese patients in a clinic from MurciaSpainESAdipose tissue, periumbilical (subcutaneous)GC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)760.330.28percentRoot0.3 percentRootCrudeGaraulet 2001
635863723AllObese patients in a clinic from MurciaSpainESAdipose tissue, intraabdominal (perivisceral)GC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)570.390.37percentRoot0.4 percentRootCrudeGaraulet 2001
638363973AllObese patients in a clinic from MurciaSpainESAdipose tissue, intraabdominal (omental)GC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)240.230.2percentRoot0.2 percentRootCrudeGaraulet 2001
7481100421AllMen in Uppsala county participant in a prospective survey on risk factors for ischemic heart diseaseSwedenSESerum (cholesterol esters), unspecifiedGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)660.660.1340.351.0percentRoot0.7 percentRootCrudeSmedman 1999
7494100431AllMen in Uppsala county participant in a prospective survey on risk factors for ischemic heart diseaseSwedenSESerum (phospholipids), unspecifiedGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)662.710.591.434.32percentRoot2.7 percentRootCrudeSmedman 1999
801580252AllMiddle-aged women in the Trondheim areaNorwayNOParticipants in a cardiovascular screening by SHUS (National Health Screening Service)Serum, non-fastingGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)2342.960.74percentRoot3.0 percentRootCrudeHjartaker 1997
804280522AllMiddle-aged women in the Trondheim areaNorwayNOParticipants in a cardiovascular screening by SHUS (National Health Screening Service)Serum, non-fastingGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)23436.2912.19mg/L36.3 mg/LCrudeHjartaker 1997
867286802All [by gender]Obese subjects with non-insulin-dependent diabetes mellitusNetherlandsNLProspective study on weight lossbaseline; 1 year; 2 yearsAdipose tissue (triglycerides), abdomenGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)530.380.11percentRoot0.4 percentRootCrudePopp-Snijders 1995
869086982MalesObese subjects with non-insulin-dependent diabetes mellitusNetherlandsNLProspective study on weight lossbaseline; 1 year; 2 yearsAdipose tissue (triglycerides), abdomenGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)190.30.08percentRoot0.3 percentRootCrudePopp-Snijders 1995
870887162FemalesObese subjects with non-insulin-dependent diabetes mellitusNetherlandsNLProspective study on weight lossbaseline; 1 year; 2 yearsAdipose tissue (triglycerides), abdomenGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)340.410.1percentRoot0.4 percentRootCrudePopp-Snijders 1995
895590502MalesAdults living in CopenhagenDenmarkDKAdipose tissue, buttocksGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)230.160.05percentRoot0.2 percentRootCrudeTjonneland 1993
898590532FemalesAdults living in CopenhagenDenmarkDKAdipose tissue, buttocksGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)630.190.07percentRoot0.2 percentRootCrudeTjonneland 1993
1014293512AllControls in a study on diet and breast cancer in Boston areaUnited StatesUSAdipose tissue, buttocksGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)1150.370.110.130.71percentRoot0.4 percentRootCrudeLondon 1991
18606186093AllWomenUnited StatesUSNYUWHS (New York University Women's Health Study)baselinePlasma, non-fastingGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)462.270.58percentRoot2.3 percentRootUnspecifiedZeleniuch-Jacquotte 2000

Intake values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionIntake toolIntake food coverageIntake time coverageIntake assessmentCompoundCompound detailSupplement intakes included?Measurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed asPublication
448144843AllControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)Dihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)2000.040.02percentRoot0.0 percentRootRegressionEnergy ?Baylin 2005
551555112AllControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)Dihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)4730.020.01percentRoot0.0 percentRootCrudeBaylin 2002
555455512AllControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)Dihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)4730.010.01g/day9.9 mg/dayRegressionEnergyBaylin 2002

Correlation values

Reproducibility values

IDMst. IDSubject groupPopulationCountryCountry codeCohortTime definitionBiological specimenExperimental methodBiomarkerBiomarker detailArithmetic meanGeometric meanMedianUnitAdjusted onReproducibility sizeICCICC 95% CI lowerICC 95% CI upperCV% WSCV% BSVAR WSVAR BSPublication
26318579AllWomenUnited StatesUSNYUWHS (New York University Women's Health Study)baseline; 1 year; 2 yearsPlasma, non-fastingGC-FIDDihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)percentRoot460.580.430.73Zeleniuch-Jacquotte 2000