alpha-Tocopherol

ID237
Namealpha-Tocopherol
Synonyms[Vitamin E] / Vitamin E; (+)-alpha-Tocopherol; D-alpha-Tocopherol
StructureThumb
DescriptionThe most important compound with vitamin E activity.
GroupTocopherols
Sub-groupTocopherols
Exposure sourceDiet
UseVitamins
CAS number59-02-9
PubChem ID14985
ChEBI ID18145
FooDB IDFDB000565
HMDB IDHMDB01893

Biomarker measurements

Biomarker concentration values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed asPublication
18660African Americans - FemalesAfrican Americans and non-Hispanic whitesUnited StatesUSSCCS (Southern Community Cohort Study)Plasma, non-fastingHPLCalpha-Tocopherol631.20.6mg/dL12.0 mg/LCrudeSignorello 2010
18730African Americans - MalesAfrican Americans and non-Hispanic whitesUnited StatesUSSCCS (Southern Community Cohort Study)Plasma, non-fastingHPLCalpha-Tocopherol621.10.3mg/dL11.0 mg/LCrudeSignorello 2010
18800Whites - FemalesAfrican Americans and non-Hispanic whitesUnited StatesUSSCCS (Southern Community Cohort Study)Plasma, non-fastingHPLCalpha-Tocopherol641.50.8mg/dL15.0 mg/LCrudeSignorello 2010
18870Whites - MalesAfrican Americans and non-Hispanic whitesUnited StatesUSSCCS (Southern Community Cohort Study)Plasma, non-fastingHPLCalpha-Tocopherol661.40.7mg/dL14.0 mg/LCrudeSignorello 2010
20200MalesEthnically diverse population with participants born in Australia, Greece, Italy or the UKAustraliaAUMCCS (Melbourne Collaborative Cohort Study)Plasma, unspecifiedHPLCalpha-Tocopherol108628.433.8741.1umol/L33870.0 nmol/LCrudeHodge 2009
20280FemalesEthnically diverse population with participants born in Australia, Greece, Italy or the UKAustraliaAUMCCS (Melbourne Collaborative Cohort Study)Plasma, unspecifiedHPLCalpha-Tocopherol202428.834.040.4umol/L34000.0 nmol/LCrudeHodge 2009
20500MalesEthnically diverse population with participants born in Australia, Greece, Italy or the UKAustraliaAUMCCS (Melbourne Collaborative Cohort Study)Plasma, unspecifiedHPLCalpha-Tocopherol10865360.06240.07380.0umol/mol6240.0 umol/molDensityCholesterolHodge 2009
20580FemalesEthnically diverse population with participants born in Australia, Greece, Italy or the UKAustraliaAUMCCS (Melbourne Collaborative Cohort Study)Plasma, unspecifiedHPLCalpha-Tocopherol20245450.06140.07020.0umol/mol6140.0 umol/molDensityCholesterolHodge 2009
21150WhitesWhites and African Americans in North CarolinaUnited StatesUSDISH (DIet, Supplements, and Health Study)Plasma, semi-fastingHPLCalpha-Tocopherol818.09.711.7umol/L9700.0 nmol/LCrudeSatia 2009
21390African AmericansWhites and African Americans in North CarolinaUnited StatesUSDISH (DIet, Supplements, and Health Study)Plasma, semi-fastingHPLCalpha-Tocopherol836.07.49.0umol/L7400.0 nmol/LCrudeSatia 2009
21610Children - MalesStudents in Shunan CityJapanJPShunan Child Cohort StudySerum, fasting and non-fastingHPLCalpha-Tocopherol11617.941umol/L17941.0 nmol/LCrudeOkuda 2009
21870Children - FemalesStudents in Shunan CityJapanJPShunan Child Cohort StudySerum, fasting and non-fastingHPLCalpha-Tocopherol10016.157umol/L16157.0 nmol/LCrudeOkuda 2009
22130Adolescents - MalesStudents in Shunan CityJapanJPShunan Child Cohort StudySerum, fasting and non-fastingHPLCalpha-Tocopherol9817.096umol/L17096.0 nmol/LCrudeOkuda 2009
22390Adolescents - FemalesStudents in Shunan CityJapanJPShunan Child Cohort StudySerum, fasting and non-fastingHPLCalpha-Tocopherol8417.066umol/L17066.0 nmol/LCrudeOkuda 2009
35120MalesAdultsFranceFRSU.VI.MAX (SUpplementation en VItamines et Mineraux AntioXydants)Serum, fastingHPLCalpha-Tocopherol148724.127.531.7umol/L27500.0 nmol/LRegressionCholesterol, TriglyceridesDauchet 2008
35330FemalesAdultsFranceFRSU.VI.MAX (SUpplementation en VItamines et Mineraux AntioXydants)Serum, fastingHPLCalpha-Tocopherol203424.528.232.4umol/L28200.0 nmol/LRegressionCholesterol, TriglyceridesDauchet 2008
37270Quartile 1 (Adherence: <38.77%, MDI)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingHPLCalpha-Tocopherol8233.4110.25umol/L33410.0 nmol/LCrudeBach-Faig 2006
37280Quartile 1 (Adherence: <3.63%, MDS)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingHPLCalpha-Tocopherol8232.9410.07umol/L32940.0 nmol/LCrudeBach-Faig 2006
37290Quartile 1 (Adherence: <38.77%, MDI)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingHPLCalpha-Tocopherol8232.086.55umol/L32080.0 nmol/LRegressionCholesterol, TriglyceridesBach-Faig 2006
37300Quartile 1 (Adherence: <3.63%, MDS)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingHPLCalpha-Tocopherol8231.795.76umol/L31790.0 nmol/LRegressionCholesterol, TriglyceridesBach-Faig 2006
37430Quartile 2 (Adherence: 38.77 to 48%, MDI)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingHPLCalpha-Tocopherol8231.098.06umol/L31090.0 nmol/LCrudeBach-Faig 2006
37440Quartile 2 (Adherence: 3.63 to 4.71%, MDS)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingHPLCalpha-Tocopherol8231.88.47umol/L31800.0 nmol/LCrudeBach-Faig 2006
37450Quartile 2 (Adherence: 38.77 to 48%, MDI)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingHPLCalpha-Tocopherol8230.545.26umol/L30540.0 nmol/LRegressionCholesterol, TriglyceridesBach-Faig 2006
37460Quartile 2 (Adherence: 3.63 to 4.71%, MDS)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingHPLCalpha-Tocopherol8231.056.94umol/L31050.0 nmol/LRegressionCholesterol, TriglyceridesBach-Faig 2006
37590Quartile 3 (Adherence: 48 to 56.24%, MDI)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingHPLCalpha-Tocopherol8235.4410.36umol/L35440.0 nmol/LCrudeBach-Faig 2006
37600Quartile 3 (Adherence: 4.71 to 5.83%, MDS)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingHPLCalpha-Tocopherol8233.798.49umol/L33790.0 nmol/LCrudeBach-Faig 2006
37610Quartile 3 (Adherence: 48 to 56.24%, MDI)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingHPLCalpha-Tocopherol8233.9211.74umol/L33920.0 nmol/LRegressionCholesterol, TriglyceridesBach-Faig 2006
37620Quartile 3 (Adherence: 4.71 to 5.83%, MDS)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingHPLCalpha-Tocopherol8230.654.82umol/L30650.0 nmol/LRegressionCholesterol, TriglyceridesBach-Faig 2006
37750Quartile 4 (Adherence: >56.24%, MDI)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingHPLCalpha-Tocopherol8233.6810.23umol/L33680.0 nmol/LCrudeBach-Faig 2006
37760Quartile 4 (Adherence: >5.83%, MDS)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingHPLCalpha-Tocopherol8235.0511.73umol/L35050.0 nmol/LCrudeBach-Faig 2006
37770Quartile 4 (Adherence: >56.24%, MDI)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingHPLCalpha-Tocopherol8231.497.07umol/L31490.0 nmol/LRegressionCholesterol, TriglyceridesBach-Faig 2006
37780Quartile 4 (Adherence: >5.83%, MDS)Adults from CataloniaSpainESCatalan Nutritional SurveySerum, fastingHPLCalpha-Tocopherol8234.3112.27umol/L34310.0 nmol/LRegressionCholesterol, TriglyceridesBach-Faig 2006
38440MalesAdultsUnited StatesUSEATS (Eating at America’s Table Study)Serum, fastingHPLCalpha-Tocopherol4425.122.028.6umol/L25100.0 nmol/LCrudeDixon 2006
38510FemalesAdultsUnited StatesUSEATS (Eating at America’s Table Study)Serum, fastingHPLCalpha-Tocopherol8628.025.730.5umol/L28000.0 nmol/LCrudeDixon 2006
46560AllParticipants in a dietary validation studyAustraliaAUNambour Skin Cancer StudySerum, non-fastingHPLCalpha-Tocopherol2834.811.420.055.0umol/L34800.0 nmol/LCrudeMcNaughton 2005
47390AllCancer patients receiving cytotoxic chemotherapy in BostonUnited StatesUSPlasma, fasting and non-fastingHPLCalpha-Tocopherol19216.032.070.0umol/L32000.0 nmol/LCrudeMeyerhardt 2005
47590AllParticipants in a dietary validation studyIsraelILDEARR (Dietary Evaluation and Attenuation of Relative Risks)Serum, fastingSpectrophotometryalpha-Tocopherol161480.65umol/L480650.0 nmol/LCrudeShai 2005
520452121BlacksElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Serum, fastingHPLCalpha-Tocopherol2931.5312.91umol/L31530.0 nmol/LCrudeTangney 2004
520552131WhitesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Serum, fastingHPLCalpha-Tocopherol3042.3519.69umol/L42350.0 nmol/LCrudeTangney 2004
520652141FemalesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Serum, fastingHPLCalpha-Tocopherol3436.3216.9umol/L36320.0 nmol/LCrudeTangney 2004
520752151MalesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Serum, fastingHPLCalpha-Tocopherol2539.2218.78umol/L39220.0 nmol/LCrudeTangney 2004
524452521BlacksElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Serum, fastingHPLCalpha-Tocopherol2933.8313.84umol/L33830.0 nmol/LRegressionCholesterol, TriglyceridesTangney 2004
524552531WhitesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Serum, fastingHPLCalpha-Tocopherol3037.9216.49umol/L37920.0 nmol/LRegressionCholesterol, TriglyceridesTangney 2004
524652541FemalesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Serum, fastingHPLCalpha-Tocopherol3434.9514.26umol/L34950.0 nmol/LRegressionCholesterol, TriglyceridesTangney 2004
524752551MalesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Serum, fastingHPLCalpha-Tocopherol2537.2716.74umol/L37270.0 nmol/LRegressionCholesterol, TriglyceridesTangney 2004
54120MalesAdolescentsCosta RicaCRPlasma, fastingHPLCalpha-Tocopherol8116.963.09umol/L16960.0 nmol/LRegressionCholesterolIrwig 2002
54260FemalesAdolescentsCosta RicaCRPlasma, fastingHPLCalpha-Tocopherol7817.092.77umol/L17090.0 nmol/LRegressionCholesterolIrwig 2002
60160AllResidents of Washington County and surrounding areasUnited StatesUSCLUE IIPlasma, non-fastingHPLCalpha-Tocopherol1160.960.20.460.810.951.121.73ug/dL0.0 mg/L0.0 mg/LCrudeBlock 2001
60680Non-Hispanic BlacksBlack and white Seventh-day Adventists participant in a dietary validation studyUnited StatesUSAHS (Adventist Health Study)Serum, fastingFluorometryalpha-Tocopherol9715.04.8ug/mL15.0 mg/LCrudeKnutsen 2001
60720Non-Hispanic Blacks - MalesBlack and white Seventh-day Adventists participant in a dietary validation studyUnited StatesUSAHS (Adventist Health Study)Serum, fastingFluorometryalpha-Tocopherol3614.03.5ug/mL14.0 mg/LCrudeKnutsen 2001
60760Non-Hispanic Blacks - FemalesBlack and white Seventh-day Adventists participant in a dietary validation studyUnited StatesUSAHS (Adventist Health Study)Serum, fastingFluorometryalpha-Tocopherol6115.65.4ug/mL15.6 mg/LCrudeKnutsen 2001
60800Non-Hispanic WhitesBlack and white Seventh-day Adventists participant in a dietary validation studyUnited StatesUSAHS (Adventist Health Study)Serum, fastingFluorometryalpha-Tocopherol9616.35.0ug/mL16.3 mg/LCrudeKnutsen 2001
60840Non-Hispanic Whites - MalesBlack and white Seventh-day Adventists participant in a dietary validation studyUnited StatesUSAHS (Adventist Health Study)Serum, fastingFluorometryalpha-Tocopherol4016.64.8ug/mL16.6 mg/LCrudeKnutsen 2001
60880Non-Hispanic Whites - FemalesBlack and white Seventh-day Adventists participant in a dietary validation studyUnited StatesUSAHS (Adventist Health Study)Serum, fastingFluorometryalpha-Tocopherol5616.15.2ug/mL16.1 mg/LCrudeKnutsen 2001
65630Supplement nonusers - MalesControls in a case-control study on diet and heart diseaseCosta RicaCRPlasma, fastingHPLCalpha-Tocopherol34728.60.4umol/L28600.0 nmol/LRegressionTriglyceridesEl-Sohemy 2001
65640Supplement nonusers - MalesControls in a case-control study on diet and heart diseaseCosta RicaCRPlasma, fastingHPLCalpha-Tocopherol34728.20.4umol/L28200.0 nmol/LRegressionAge, Smoking, BMIEl-Sohemy 2001
65650Supplement nonusers - MalesControls in a case-control study on diet and heart diseaseCosta RicaCRAdipose tissue, buttocksHPLCalpha-Tocopherol34782.93.0ug/g82.9 ug/gCrudeEl-Sohemy 2001
65660Supplement nonusers - MalesControls in a case-control study on diet and heart diseaseCosta RicaCRAdipose tissue, buttocksHPLCalpha-Tocopherol34779.53.2ug/g79.5 ug/gRegressionAge, Smoking, BMIEl-Sohemy 2001
65690Supplement nonusers - FemalesControls in a case-control study on diet and heart diseaseCosta RicaCRPlasma, fastingHPLCalpha-Tocopherol11131.80.8umol/L31800.0 nmol/LRegressionTriglyceridesEl-Sohemy 2001
65700Supplement nonusers - FemalesControls in a case-control study on diet and heart diseaseCosta RicaCRPlasma, fastingHPLCalpha-Tocopherol11130.91.1umol/L30900.0 nmol/LRegressionAge, Smoking, BMIEl-Sohemy 2001
65710Supplement nonusers - FemalesControls in a case-control study on diet and heart diseaseCosta RicaCRAdipose tissue, buttocksHPLCalpha-Tocopherol111123.16.6ug/g123.1 ug/gCrudeEl-Sohemy 2001
65720Supplement nonusers - FemalesControls in a case-control study on diet and heart diseaseCosta RicaCRAdipose tissue, buttocksHPLCalpha-Tocopherol111118.77.3ug/g118.7 ug/gRegressionAge, Smoking, BMIEl-Sohemy 2001
72650AllWomen in the southern part of Mexico CityMexicoMXPlasma, non-fastingHPLCalpha-Tocopherol11010.22.9mg/L10.2 mg/LCrudeRomieu 1999
74010MalesParticipants in an investigation of antioxidant intake and adult onset asthma in ScotlandUnited KingdomGBPlasma, unspecifiedHPLCalpha-Tocopherol11828.37.714.927.570.2umol/L28300.0 nmol/L27500.0 nmol/LCrudeBodner 1998
74050FemalesParticipants in an investigation of antioxidant intake and adult onset asthma in ScotlandUnited KingdomGBPlasma, unspecifiedHPLCalpha-Tocopherol15524.96.013.824.246.9umol/L24900.0 nmol/L24200.0 nmol/LCrudeBodner 1998
76560AllMen from Oerland military flight stationNorwayNOAdipose tissue, buttocksHPLCalpha-Tocopherol119216.7420.6735.3ug/g420.6 ug/gDensityFatty acidsAndersen 1999
76670AllMen from Oerland military flight stationNorwayNOSerum, fastingHPLCalpha-Tocopherol13520.624.530.6umol/L24500.0 nmol/LCrudeAndersen 1999
81650AllMen from a large clinical trialUnited StatesUSPolyp Prevention TrialSerum, fastingHPLCalpha-Tocopherol16227.18.811.978.4umol/L27100.0 nmol/LCrudeMarshall 1997
81700Young malesParticipants in a vitamin K metabolic study in New England regionUnited StatesUSPlasma, fastingHPLCalpha-Tocopherol919.7umol/L19700.0 nmol/LCrudeBooth 1997
81740Young femalesParticipants in a vitamin K metabolic study in New England regionUnited StatesUSPlasma, fastingHPLCalpha-Tocopherol817.8umol/L17800.0 nmol/LCrudeBooth 1997
81780Old malesParticipants in a vitamin K metabolic study in New England regionUnited StatesUSPlasma, fastingHPLCalpha-Tocopherol927.9umol/L27900.0 nmol/LCrudeBooth 1997
81820Old femalesParticipants in a vitamin K metabolic study in New England regionUnited StatesUSPlasma, fastingHPLCalpha-Tocopherol826.3umol/L26300.0 nmol/LCrudeBooth 1997
82340AllAdults in MataróSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Plasma, fastingHPLCalpha-Tocopherol72960.3210.3ug/dL9.6 mg/LCrudeGonzalez 1997
82430MalesAdults in MataróSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Plasma, fastingHPLCalpha-Tocopherol32950.5183.0ug/dL9.5 mg/LCrudeGonzalez 1997
82520FemalesAdults in MataróSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Plasma, fastingHPLCalpha-Tocopherol40967.9231.3ug/dL9.7 mg/LCrudeGonzalez 1997
82610SmokersAdults in MataróSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Plasma, fastingHPLCalpha-Tocopherol161025.6206.5ug/dL10.3 mg/LCrudeGonzalez 1997
82700Non-smokersAdults in MataróSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Plasma, fastingHPLCalpha-Tocopherol56941.3209.5ug/dL9.4 mg/LCrudeGonzalez 1997
85130AllStudents and technicians attending the Agriculture Faculty and the Nursing School of San Carlo Hospital of MilanItalyITPlasma, fastingHPLCalpha-Tocopherol3811.52.5ug/mL11.5 mg/LCrudePorrini 1995
87370AllVolunteers from the University of Minnesota communityUnited StatesUSPlasma, fastingHPLCalpha-Tocopherol990.80.2mg/dL8.0 mg/LCrudeCampbell 1994
89050FemalesChildren in GeorgiaUnited StatesUSSCAN (Studies of Children's Activity and Nutrition)Serum, non-fastingHPLCalpha-Tocopherol54745.0iualphatocopherol/dL745.0 mg/LCrudeByers 1993
89110MalesChildren in GeorgiaUnited StatesUSSCAN (Studies of Children's Activity and Nutrition)Serum, non-fastingHPLCalpha-Tocopherol43762.0iualphatocopherol/dL762.0 mg/LCrudeByers 1993
91450MalesParticipants in a case-control study of nutritional status and age-related cataractsUnited StatesUSPlasma, unspecifiedHPLCalpha-Tocopherol5530.012.0umol/L30000.0 nmol/LCrudeJacques 1993
91550Males - Supplement nonusersParticipants in a case-control study of nutritional status and age-related cataractsUnited StatesUSPlasma, unspecifiedHPLCalpha-Tocopherol4126.08.0umol/L26000.0 nmol/LCrudeJacques 1993
91650FemalesParticipants in a case-control study of nutritional status and age-related cataractsUnited StatesUSPlasma, unspecifiedHPLCalpha-Tocopherol8228.011.0umol/L28000.0 nmol/LCrudeJacques 1993
91750Females - Supplement nonusersParticipants in a case-control study of nutritional status and age-related cataractsUnited StatesUSPlasma, unspecifiedHPLCalpha-Tocopherol7026.07.3umol/L26000.0 nmol/LCrudeJacques 1993
92360All [HPFS]Men living in the Boston areaUnited StatesUSHPFS (Health Professionals Follow-Up Study)Plasma, non-fastingHPLCalpha-Tocopherol12127.18.4umol/L27100.0 nmol/LCrudeAscherio 1992
92460All [NHS]Women living in the Boston areaUnited StatesUSNHS (Nurses' Health Study)Plasma, non-fastingHPLCalpha-Tocopherol18626.28.4umol/L26200.0 nmol/LCrudeAscherio 1992
93980SmokersMen smokers and non-smokers in ScotlandUnited KingdomGBSerum, non-fastingMissingalpha-Tocopherol799.92.9mg/L9.9 mg/LCrudeBolton-Smith 1991
93990SmokersMen smokers and non-smokers in ScotlandUnited KingdomGBSerum, non-fastingMissingalpha-Tocopherol791.580.43mg/mmol1580000.0 ug/molDensityCholesterolBolton-Smith 1991
94060Non-smokersMen smokers and non-smokers in ScotlandUnited KingdomGBSerum, non-fastingMissingalpha-Tocopherol11710.92.5mg/L10.9 mg/LCrudeBolton-Smith 1991
94070Non-smokersMen smokers and non-smokers in ScotlandUnited KingdomGBSerum, non-fastingMissingalpha-Tocopherol1171.770.32mg/mmol1770000.0 ug/molDensityCholesterolBolton-Smith 1991
98870AllStaff members of laboratory and health centers in Boston areaUnited StatesUSRandomized trial on vitamin supplementsPlasma, fastingHPLCalpha-Tocopherol581.030.27mg/dL10.3 mg/LCrudeWillett 1983
18268182742AllHawaii womenUnited StatesUSCohort study of cervical human papillomavirus at the Cancer Research Center of Hawaiibaseline; month 4; month 8; month 12Plasma, fastingHPLCalpha-Tocopherol38110587.04406.03490.09524.041500.0ng/mL10.6 mg/L9.5 mg/LCrudeShvetsov 2009
184720AllSmokers and nonsmokers exposed to second-hand smokeUnited StatesUSStudy on the effect of antioxidant supplements on oxidative damage in active and passive smokersbaseline; 2 weeksPlasma, fastingHPLCalpha-Tocopherol2061.280.541.18mg/dL12.8 mg/L11.8 mg/LCrudeBlock 2006
186360AllNursesUnited StatesUSNHS (Nurses' Health Study)baseline; 2 yearsPlasma, unspecifiedHPLCalpha-Tocopherol407336.011535.022844.0ug/L11.5 mg/LCrudeKotsopoulos 2010

Intake values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionIntake toolIntake food coverageIntake time coverageIntake assessmentCompoundCompound detailSupplement intakes included?Measurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed asPublication
11780MalesParticipants in a dietary validation studyJapanJPJPHC StudybaselineCalculated with FDB_raw databaseDietary record (7-day)alpha-Tocopherol10210.63.5mg/day10.6 mg/dayCrudeKobayashi 2011
11940MalesParticipants in a dietary validation studyJapanJPJPHC StudybaselineCalculated with FDB_cook databaseDietary record (7-day)alpha-Tocopherol10210.44.6mg/day10.4 mg/dayCrudeKobayashi 2011
12090FemalesParticipants in a dietary validation studyJapanJPJPHC StudybaselineCalculated with FDB_raw databaseDietary record (7-day)alpha-Tocopherol11310.44.3mg/day10.4 mg/dayCrudeKobayashi 2011
12240FemalesParticipants in a dietary validation studyJapanJPJPHC StudybaselineCalculated with FDB_cook databaseDietary record (7-day)alpha-Tocopherol11310.24.8mg/day10.2 mg/dayCrudeKobayashi 2011
18380African Americans - FemalesAfrican Americans and non-Hispanic whitesUnited StatesUSSCCS (Southern Community Cohort Study)Food Frequency Questionnaire (FFQ)alpha-TocopherolNo637.94.5mg/day7.9 mg/dayCrudeSignorello 2010
18450African Americans - MalesAfrican Americans and non-Hispanic whitesUnited StatesUSSCCS (Southern Community Cohort Study)Food Frequency Questionnaire (FFQ)alpha-TocopherolNo6210.65.7mg/day10.6 mg/dayCrudeSignorello 2010
18520Whites - FemalesAfrican Americans and non-Hispanic whitesUnited StatesUSSCCS (Southern Community Cohort Study)Food Frequency Questionnaire (FFQ)alpha-TocopherolNo646.92.4mg/day6.9 mg/dayCrudeSignorello 2010
18590Whites - MalesAfrican Americans and non-Hispanic whitesUnited StatesUSSCCS (Southern Community Cohort Study)Food Frequency Questionnaire (FFQ)alpha-TocopherolNo669.15.2mg/day9.1 mg/dayCrudeSignorello 2010
20990WhitesWhites and African Americans in North CarolinaUnited StatesUSDISH (DIet, Supplements, and Health Study)Food Frequency Questionnaire (FFQ)alpha-Tocopherol817.312.817.8mg/day12.8 mg/dayCrudeSatia 2009
21070WhitesWhites and African Americans in North CarolinaUnited StatesUSDISH (DIet, Supplements, and Health Study)24-h Dietary recall (1-day)alpha-Tocopherol816.59.713.6mg/day9.7 mg/dayCrudeSatia 2009
21230African AmericansWhites and African Americans in North CarolinaUnited StatesUSDISH (DIet, Supplements, and Health Study)Food Frequency Questionnaire (FFQ)alpha-Tocopherol833.87.612.5mg/day7.6 mg/dayCrudeSatia 2009
21310African AmericansWhites and African Americans in North CarolinaUnited StatesUSDISH (DIet, Supplements, and Health Study)24-h Dietary recall (1-day)alpha-Tocopherol835.16.99.3mg/day6.9 mg/dayCrudeSatia 2009
21440Children - MalesStudents in Shunan CityJapanJPShunan Child Cohort StudyDiet History Questionnaire (DHQ)alpha-Tocopherol1163.8mg/1000 kcal3.8 mg/1000 kcalDensityEnergyOkuda 2009
21700Children - FemalesStudents in Shunan CityJapanJPShunan Child Cohort StudyDiet History Questionnaire (DHQ)alpha-Tocopherol1004.3mg/1000 kcal4.3 mg/1000 kcalDensityEnergyOkuda 2009
21960Adolescents - MalesStudents in Shunan CityJapanJPShunan Child Cohort StudyDiet History Questionnaire (DHQ)alpha-Tocopherol984.1mg/1000 kcal4.1 mg/1000 kcalDensityEnergyOkuda 2009
22220Adolescents - FemalesStudents in Shunan CityJapanJPShunan Child Cohort StudyDiet History Questionnaire (DHQ)alpha-Tocopherol844.4mg/1000 kcal4.4 mg/1000 kcalDensityEnergyOkuda 2009
38600MalesAdultsUnited StatesUSEATS (Eating at America’s Table Study)Diet History Questionnaire (DHQ)alpha-TocopherolNo447.76.49.3mg/day7.7 mg/dayCrudeDixon 2006
38620MalesAdultsUnited StatesUSEATS (Eating at America’s Table Study)Diet History Questionnaire (DHQ)alpha-TocopherolYes4420.013.031.0mg/day20.0 mg/dayCrudeDixon 2006
38700MalesAdultsUnited StatesUSEATS (Eating at America’s Table Study)24-h Dietary recall (1-day)alpha-TocopherolNo448.97.710.2mg/day8.9 mg/dayCrudeDixon 2006
38720MalesAdultsUnited StatesUSEATS (Eating at America’s Table Study)24-h Dietary recall (1-day)alpha-TocopherolYes4427.017.040.0mg/day27.0 mg/dayCrudeDixon 2006
38800FemalesAdultsUnited StatesUSEATS (Eating at America’s Table Study)Diet History Questionnaire (DHQ)alpha-TocopherolNo866.76.07.5mg/day6.7 mg/dayCrudeDixon 2006
38820FemalesAdultsUnited StatesUSEATS (Eating at America’s Table Study)Diet History Questionnaire (DHQ)alpha-TocopherolYes8627.020.037.0mg/day27.0 mg/dayCrudeDixon 2006
38900FemalesAdultsUnited StatesUSEATS (Eating at America’s Table Study)24-h Dietary recall (1-day)alpha-TocopherolNo866.35.86.9mg/day6.3 mg/dayCrudeDixon 2006
38920FemalesAdultsUnited StatesUSEATS (Eating at America’s Table Study)24-h Dietary recall (1-day)alpha-TocopherolYes8633.024.046.0mg/day33.0 mg/dayCrudeDixon 2006
49960BlacksElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Food Frequency Questionnaire (FFQ)alpha-TocopherolYes2948.791.3mg/day48.7 mg/dayCrudeTangney 2004
49970WhitesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Food Frequency Questionnaire (FFQ)alpha-TocopherolYes30171.8250.7mg/day171.8 mg/dayCrudeTangney 2004
49980FemalesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Food Frequency Questionnaire (FFQ)alpha-TocopherolYes3475.5139.2mg/day75.5 mg/dayCrudeTangney 2004
49990MalesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Food Frequency Questionnaire (FFQ)alpha-TocopherolYes25170.6256.4mg/day170.6 mg/dayCrudeTangney 2004
50000BlacksElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Food Frequency Questionnaire (FFQ)alpha-TocopherolNo295.82.3mg/day5.8 mg/dayCrudeTangney 2004
50010WhitesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Food Frequency Questionnaire (FFQ)alpha-TocopherolNo306.63.5mg/day6.6 mg/dayCrudeTangney 2004
50020FemalesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Food Frequency Questionnaire (FFQ)alpha-TocopherolNo347.43.3mg/day7.4 mg/dayCrudeTangney 2004
50030MalesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Food Frequency Questionnaire (FFQ)alpha-TocopherolNo258.83.5mg/day8.8 mg/dayCrudeTangney 2004
50560BlacksElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Food Frequency Questionnaire (FFQ)alpha-TocopherolYes2948.489.7mg/day48.4 mg/dayRegressionEnergyTangney 2004
50570WhitesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Food Frequency Questionnaire (FFQ)alpha-TocopherolYes30171.0248.3mg/day171.0 mg/dayRegressionEnergyTangney 2004
50580FemalesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Food Frequency Questionnaire (FFQ)alpha-TocopherolYes3486.1156.9mg/day86.1 mg/dayRegressionEnergyTangney 2004
50590MalesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Food Frequency Questionnaire (FFQ)alpha-TocopherolYes25147.6213.8mg/day147.6 mg/dayRegressionEnergyTangney 2004
50600BlacksElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Food Frequency Questionnaire (FFQ)alpha-TocopherolNo296.12.2mg/day6.1 mg/dayRegressionEnergyTangney 2004
50610WhitesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Food Frequency Questionnaire (FFQ)alpha-TocopherolNo306.22.8mg/day6.2 mg/dayRegressionEnergyTangney 2004
50620FemalesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Food Frequency Questionnaire (FFQ)alpha-TocopherolNo347.62.6mg/day7.6 mg/dayRegressionEnergyTangney 2004
50630MalesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)Food Frequency Questionnaire (FFQ)alpha-TocopherolNo257.52.4mg/day7.5 mg/dayRegressionEnergyTangney 2004
51160BlacksElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)24-h Dietary recall (1-day)alpha-TocopherolYes2917.926.2mg/day17.9 mg/dayCrudeTangney 2004
51170WhitesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)24-h Dietary recall (1-day)alpha-TocopherolYes3073.088.8mg/day73.0 mg/dayCrudeTangney 2004
51180FemalesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)24-h Dietary recall (1-day)alpha-TocopherolYes3441.275.1mg/day41.2 mg/dayCrudeTangney 2004
51190MalesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)24-h Dietary recall (1-day)alpha-TocopherolYes2551.278.4mg/day51.2 mg/dayCrudeTangney 2004
51200BlacksElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)24-h Dietary recall (1-day)alpha-TocopherolNo297.33.9mg/day7.3 mg/dayCrudeTangney 2004
51210WhitesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)24-h Dietary recall (1-day)alpha-TocopherolNo308.73.8mg/day8.7 mg/dayCrudeTangney 2004
51220FemalesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)24-h Dietary recall (1-day)alpha-TocopherolNo345.43.1mg/day5.4 mg/dayCrudeTangney 2004
51230MalesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)24-h Dietary recall (1-day)alpha-TocopherolNo256.16.2mg/day6.1 mg/dayCrudeTangney 2004
51600BlacksElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)24-h Dietary recall (1-day)alpha-TocopherolYes2920.329.9mg/day20.3 mg/dayRegressionEnergyTangney 2004
51610WhitesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)24-h Dietary recall (1-day)alpha-TocopherolYes3066.1107.3mg/day66.1 mg/dayRegressionEnergyTangney 2004
51620FemalesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)24-h Dietary recall (1-day)alpha-TocopherolYes3441.275.1mg/day41.2 mg/dayRegressionEnergyTangney 2004
51630MalesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)24-h Dietary recall (1-day)alpha-TocopherolYes2540.367.5mg/day40.3 mg/dayRegressionEnergyTangney 2004
51640BlacksElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)24-h Dietary recall (1-day)alpha-TocopherolNo294.71.2mg/day4.7 mg/dayRegressionEnergyTangney 2004
51650WhitesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)24-h Dietary recall (1-day)alpha-TocopherolNo305.82.9mg/day5.8 mg/dayRegressionEnergyTangney 2004
51660FemalesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)24-h Dietary recall (1-day)alpha-TocopherolNo345.32.0mg/day5.3 mg/dayRegressionEnergyTangney 2004
51670MalesElderly black and white participants in a dietary validation studyUnited StatesUSCHAP (Chicago Health and Aging Project)24-h Dietary recall (1-day)alpha-TocopherolNo255.03.0mg/day5.0 mg/dayRegressionEnergyTangney 2004
54050MalesAdolescentsCosta RicaCRFood Frequency Questionnaire (FFQ)alpha-Tocopherol8117.442.2mg/day17.4 mg/dayRegressionEnergyIrwig 2002
54190FemalesAdolescentsCosta RicaCRFood Frequency Questionnaire (FFQ)alpha-Tocopherol7819.260.0mg/day19.2 mg/dayRegressionEnergyIrwig 2002
57820AllControls in a case-control study on diet and heart diseaseCosta RicaCR24-h Dietary recall (1-day)alpha-Tocopherol1203.01.2ug/day0.0 mg/dayCrudeKabagambe 2001
58080AllControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)alpha-Tocopherol1209.04.1ug/day0.0 mg/dayCrudeKabagambe 2001
58340AllControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)alpha-Tocopherol1209.55.6ug/day0.0 mg/dayCrudeKabagambe 2001
58600AllControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)alpha-Tocopherol1209.34.2ug/day0.0 mg/dayCrudeKabagambe 2001
65610Supplement nonusers - MalesControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)alpha-TocopherolNo3478.70.2mg/day8.7 mg/dayRegressionEnergyEl-Sohemy 2001
65620Supplement nonusers - MalesControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)alpha-TocopherolNo3478.60.3mg/day8.6 mg/dayRegressionAge, Smoking, BMIEl-Sohemy 2001
65670Supplement nonusers - FemalesControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)alpha-TocopherolNo1119.70.6mg/day9.7 mg/dayRegressionEnergyEl-Sohemy 2001
65680Supplement nonusers - FemalesControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)alpha-TocopherolNo1119.20.6mg/day9.2 mg/dayRegressionAge, Smoking, BMIEl-Sohemy 2001
72730AllWomen in the southern part of Mexico CityMexicoMX24-h Dietary recall (4-day)alpha-Tocopherol1103.191.05mg/day3.2 mg/dayCrudeRomieu 1999
72830AllWomen in the southern part of Mexico CityMexicoMXFood Frequency Questionnaire (FFQ)alpha-Tocopherol1105.262.48mg/day5.3 mg/dayCrudeRomieu 1999
72930AllWomen in the southern part of Mexico CityMexicoMXFood Frequency Questionnaire (FFQ)alpha-Tocopherol1104.221.75mg/day4.2 mg/dayCrudeRomieu 1999
76350AllMen from Oerland military flight stationNorwayNOFood Frequency Questionnaire (FFQ)alpha-TocopherolYes1357.911.315.5mg/day11.3 mg/dayCrudeAndersen 1999
82740AllAdults in MataróSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Diet History Questionnaire (DHQ)alpha-Tocopherol7210.34.1ug/dL0.1 mg/LCrudeGonzalez 1997
82780AllAdults in MataróSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)24-h Dietary recall (1-day)alpha-Tocopherol729.42.8ug/dL0.1 mg/LCrudeGonzalez 1997
82820MalesAdults in MataróSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Diet History Questionnaire (DHQ)alpha-Tocopherol3211.43.9ug/dL0.1 mg/LCrudeGonzalez 1997
82860MalesAdults in MataróSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)24-h Dietary recall (1-day)alpha-Tocopherol3210.03.0ug/dL0.1 mg/LCrudeGonzalez 1997
82900FemalesAdults in MataróSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Diet History Questionnaire (DHQ)alpha-Tocopherol409.54.0ug/dL0.1 mg/LCrudeGonzalez 1997
82940FemalesAdults in MataróSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)24-h Dietary recall (1-day)alpha-Tocopherol408.92.6ug/dL0.1 mg/LCrudeGonzalez 1997
85160AllStudents and technicians attending the Agriculture Faculty and the Nursing School of San Carlo Hospital of MilanItalyITFood Frequency Questionnaire (FFQ)alpha-TocopherolNo384.41.0mg/day4.4 mg/dayCrudePorrini 1995
85190AllStudents and technicians attending the Agriculture Faculty and the Nursing School of San Carlo Hospital of MilanItalyITWeighed Dietary record (7-day)alpha-TocopherolNo383.71.1mg/day3.7 mg/dayCrudePorrini 1995

Correlation values

Reproducibility values

IDMst. IDSubject groupPopulationCountryCountry codeCohortTime definitionBiological specimenExperimental methodBiomarkerBiomarker detailArithmetic meanGeometric meanMedianUnitAdjusted onReproducibility sizeICCICC 95% CI lowerICC 95% CI upperCV% WSCV% BSVAR WSVAR BSPublication
351757All [by diagnosis]Elderly subjects with and without mild cognitive impairmentUnited StatesUSbaseline; 1 monthPlasma, fastingHPLCalpha-Tocopherolmissing unit380.95Bowman 2011
581735No cognitive impairmentElderly subjects with and without mild cognitive impairmentUnited StatesUSbaseline; 1 monthPlasma, fastingHPLCalpha-Tocopherolmissing unit190.97Bowman 2011
801713Mild cognitive impairmentElderly subjects with and without mild cognitive impairmentUnited StatesUSbaseline; 1 monthPlasma, fastingHPLCalpha-Tocopherolmissing unit190.9Bowman 2011
12718268AllHawaii womenUnited StatesUSCohort study of cervical human papillomavirus at the Cancer Research Center of Hawaiibaseline; month 4; month 8; month 12Plasma, fastingHPLCalpha-Tocopherol10587.09524.0ng/mL3810.620.0020.004Shvetsov 2009
17718472AllSmokers and nonsmokers exposed to second-hand smokeUnited StatesUSStudy on the effect of antioxidant supplements on oxidative damage in active and passive smokersbaseline; 2 weeksPlasma, fastingHPLCalpha-Tocopherol1.281.18mg/dL2060.630.0290.048Block 2006
29318636AllNursesUnited StatesUSNHS (Nurses' Health Study)baseline; 2 yearsPlasma, unspecifiedHPLCalpha-Tocopherol11535.0ug/L400.830.720.9113.229.8Kotsopoulos 2010
61619087AllDutch participants of the EPIC-StudyNetherlandsNLMORGEN-EPIC projectbaseline; 3 yearsPlasma, non-fastingHPLCalpha-Tocopherolnmol/L620.430.240.59Leenders 2013