Exposome-Explorer: show components

Flavanones

ID	27
Name	Flavanones
Synonyms
Structure
Description
Group	Polyphenols
Sub-group	Flavanones
Exposure source	Diet
Use
CAS number
PubChem ID
ChEBI ID
FooDB ID
HMDB ID

Biomarker measurements

Biomarkers
Biospecimens
Analytical methods
Cohorts
Publications

Title	First author	Year
Fasting plasma concentrations of selected flavonoids as markers of their ordinary dietary intake	Radtke	2002
Urine flavonoids and plasma carotenoids in the validation of fruit, vegetable and tea intake during pregnancy in the Norwegian Mother and Child Cohort Study (MoBa)	Brantsaeter	2007
Free fruit at workplace intervention increases total fruit intake: a validation study using 24 h dietary recall and urinary flavonoid excretion	Krogholm	2010

Analytical method
HPLC after enzymatic hydrolysis
LC-MS after enzymatic hydrolysis

Biospecimen
Urine, 24-h
Plasma, fasting

Cohort
MoBa (Norwegian Mother and Child Cohort)

Biomarker
Quercetin
Kaempferol
Flavonols
Naringenin
Hesperetin
Flavanones

Biomarker concentration values

ID	Parent ID	Depth	Subject group	Population	Country	Country code	Biospecimen	Analytical method	Biomarker	Biomarker detail	Measurement size	Percentile_05	Median	Percentile_95	Unit	Converted median	Adjustment type	Publication
782	10333	2	Controls	Employees at workplaces in Copenhagen area with or without a free-fruit program intervention	Denmark	DK	Urine, 24-h	HPLC after enzymatic hydrolysis	Flavanones	Eriodictyol Hesperetin Naringenin	45	8.0	169.0	1166.0	ug/day	0.2 mg/day	Crude	Krogholm 2010
792	10340	2	Controls	Employees at workplaces in Copenhagen area with or without a free-fruit program intervention	Denmark	DK	Urine, 24-h	HPLC after enzymatic hydrolysis	Flavanones	Eriodictyol Hesperetin Naringenin	45	8.0	317.0	4244.0	ug/day	0.3 mg/day	Crude	Krogholm 2010
802	10354	2	Intervention	Employees at workplaces in Copenhagen area with or without a free-fruit program intervention	Denmark	DK	Urine, 24-h	HPLC after enzymatic hydrolysis	Flavanones	Eriodictyol Hesperetin Naringenin	34	8.0	91.0	1852.0	ug/day	0.1 mg/day	Crude	Krogholm 2010
812	10347	2	Intervention	Employees at workplaces in Copenhagen area with or without a free-fruit program intervention	Denmark	DK	Urine, 24-h	HPLC after enzymatic hydrolysis	Flavanones	Eriodictyol Hesperetin Naringenin	34	9.0	493.0	7899.0	ug/day	0.5 mg/day	Crude	Krogholm 2010

Intake values

No data available

Correlation values

Flavanones intakes correlated with excretions
Flavanones excretions correlated with intakes

ID	Intake ID	Excretion ID	Subject group	Population	Country	Country code	Intake assessment	Intake	Intake detail	Intake Unit	Biological specimen	Biomarker Experimental method	Biomarker	Biomarker detail	Biomarker Arithmetic mean	Biomarker Median	Biomarker Unit	Correlation size	Correlation type	Correlation value	Correlation p-value	Significant?	Publication
75	141	94	All	Female university students	Germany	DE	Dietary record (1-day)	Flavanones	Hesperetin Naringenin	mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Quercetin		22.87	20.26	nmol/L	48	Spearman	0.03	>= 0.05	No	Radtke 2002
87	141	95	All	Female university students	Germany	DE	Dietary record (1-day)	Flavanones	Hesperetin Naringenin	mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Kaempferol		10.65	8.72	nmol/L	48	Spearman	-0.07	>= 0.05	No	Radtke 2002
99	141	145	All	Female university students	Germany	DE	Dietary record (1-day)	Flavanones	Hesperetin Naringenin	mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Flavonols	Kaempferol Quercetin			nmol/L	47	Spearman	-0.01	>= 0.05	No	Radtke 2002
111	141	96	All	Female university students	Germany	DE	Dietary record (1-day)	Flavanones	Hesperetin Naringenin	mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Naringenin		8.15	0.0	nmol/L	45	Spearman	0.44	< 0.01	Yes	Radtke 2002
123	141	97	All	Female university students	Germany	DE	Dietary record (1-day)	Flavanones	Hesperetin Naringenin	mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Hesperetin		22.16	5.75	nmol/L	47	Spearman	0.63	< 0.01	Yes	Radtke 2002
135	141	146	All	Female university students	Germany	DE	Dietary record (1-day)	Flavanones	Hesperetin Naringenin	mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Flavanones	Hesperetin Naringenin			nmol/L	45	Spearman	0.57	< 0.01	Yes	Radtke 2002
69	143	94	All	Female university students	Germany	DE	Dietary record (7-day)	Flavanones	Hesperetin Naringenin	mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Quercetin		22.87	20.26	nmol/L	48	Spearman	0.02	>= 0.05	No	Radtke 2002
81	143	95	All	Female university students	Germany	DE	Dietary record (7-day)	Flavanones	Hesperetin Naringenin	mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Kaempferol		10.65	8.72	nmol/L	48	Spearman	-0.12	>= 0.05	No	Radtke 2002
93	143	145	All	Female university students	Germany	DE	Dietary record (7-day)	Flavanones	Hesperetin Naringenin	mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Flavonols	Kaempferol Quercetin			nmol/L	47	Spearman	-0.02	>= 0.05	No	Radtke 2002
105	143	96	All	Female university students	Germany	DE	Dietary record (7-day)	Flavanones	Hesperetin Naringenin	mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Naringenin		8.15	0.0	nmol/L	45	Spearman	0.36	< 0.05	Yes	Radtke 2002
117	143	97	All	Female university students	Germany	DE	Dietary record (7-day)	Flavanones	Hesperetin Naringenin	mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Hesperetin		22.16	5.75	nmol/L	47	Spearman	0.46	< 0.01	Yes	Radtke 2002
129	143	146	All	Female university students	Germany	DE	Dietary record (7-day)	Flavanones	Hesperetin Naringenin	mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Flavanones	Hesperetin Naringenin			nmol/L	45	Spearman	0.42	< 0.01	Yes	Radtke 2002

ID	Intake ID	Excretion ID	Subject group	Population	Country	Country code	Cohort	Intake assessment	Intake	Intake detail	Intake Arithmetic mean	Intake Median	Intake Unit	Biological specimen	Biomarker Experimental method	Biomarker	Biomarker detail	Biomarker Unit	Correlation size	Correlation type	Correlation value	Correlation 95% CI lower	Correlation 95% CI upper	Correlation p-value	Significant?	Publication
124	86	146	All	Female university students	Germany	DE		Dietary record (7-day)	Quercetin		17.89	17.25	mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Flavanones	Hesperetin Naringenin	nmol/L	45	Spearman	0.01			>= 0.05	No	Radtke 2002
125	87	146	All	Female university students	Germany	DE		Dietary record (7-day)	Kaempferol		4.72	3.16	mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Flavanones	Hesperetin Naringenin	nmol/L	45	Spearman	0.0			>= 0.05	No	Radtke 2002
126	144	146	All	Female university students	Germany	DE		Dietary record (7-day)	Flavonols	Kaempferol Quercetin			mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Flavanones	Hesperetin Naringenin	nmol/L	45	Spearman	0.01			>= 0.05	No	Radtke 2002
127	88	146	All	Female university students	Germany	DE		Dietary record (7-day)	Naringenin		12.11	5.45	mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Flavanones	Hesperetin Naringenin	nmol/L	45	Spearman	0.45			< 0.01	Yes	Radtke 2002
128	89	146	All	Female university students	Germany	DE		Dietary record (7-day)	Hesperetin		17.37	13.06	mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Flavanones	Hesperetin Naringenin	nmol/L	45	Spearman	0.3			< 0.05	Yes	Radtke 2002
129	143	146	All	Female university students	Germany	DE		Dietary record (7-day)	Flavanones	Hesperetin Naringenin			mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Flavanones	Hesperetin Naringenin	nmol/L	45	Spearman	0.42			< 0.01	Yes	Radtke 2002
130	90	146	All	Female university students	Germany	DE		Dietary record (1-day)	Quercetin		24.0	16.53	mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Flavanones	Hesperetin Naringenin	nmol/L	45	Spearman	0.03			>= 0.05	No	Radtke 2002
131	91	146	All	Female university students	Germany	DE		Dietary record (1-day)	Kaempferol		5.27	2.21	mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Flavanones	Hesperetin Naringenin	nmol/L	45	Spearman	0.0			>= 0.05	No	Radtke 2002
132	142	146	All	Female university students	Germany	DE		Dietary record (1-day)	Flavonols	Kaempferol Quercetin			mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Flavanones	Hesperetin Naringenin	nmol/L	45	Spearman	0.01			>= 0.05	No	Radtke 2002
133	92	146	All	Female university students	Germany	DE		Dietary record (1-day)	Naringenin		9.38	0.43	mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Flavanones	Hesperetin Naringenin	nmol/L	45	Spearman	0.6			< 0.01	Yes	Radtke 2002
134	93	146	All	Female university students	Germany	DE		Dietary record (1-day)	Hesperetin		14.39	2.43	mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Flavanones	Hesperetin Naringenin	nmol/L	45	Spearman	0.59			< 0.01	Yes	Radtke 2002
135	141	146	All	Female university students	Germany	DE		Dietary record (1-day)	Flavanones	Hesperetin Naringenin			mg/day	Plasma, fasting	HPLC after enzymatic hydrolysis	Flavanones	Hesperetin Naringenin	nmol/L	45	Spearman	0.57			< 0.01	Yes	Radtke 2002
404	431	581	Flavonoid supplement nonusers	Participants in the validation study of the MoBa cohort	Norway	NO	MoBa (Norwegian Mother and Child Cohort)	Food Frequency Questionnaire (FFQ)	Citrus fruits				g/day	Urine, 24-h	LC-MS after enzymatic hydrolysis	Flavanones	Eriodictyol Hesperetin Naringenin	umol/L	99	Pearson	0.41			< 0.01	Yes	Brantsaeter 2007
424	451	581	Flavonoid supplement nonusers	Participants in the validation study of the MoBa cohort	Norway	NO	MoBa (Norwegian Mother and Child Cohort)	Food Frequency Questionnaire (FFQ)	Fruits + Vegetables	Apple Carrot Fruit juices Tomato Vegetables			g/day	Urine, 24-h	LC-MS after enzymatic hydrolysis	Flavanones	Eriodictyol Hesperetin Naringenin	umol/L	99	Pearson	0.18			>= 0.05	No	Brantsaeter 2007
438	469	581	Flavonoid supplement nonusers	Participants in the validation study of the MoBa cohort	Norway	NO	MoBa (Norwegian Mother and Child Cohort)	Weighed Dietary record (4-day)	Citrus fruits				g/day	Urine, 24-h	LC-MS after enzymatic hydrolysis	Flavanones	Eriodictyol Hesperetin Naringenin	umol/L	99	Pearson	0.66			< 0.01	Yes	Brantsaeter 2007
458	489	581	Flavonoid supplement nonusers	Participants in the validation study of the MoBa cohort	Norway	NO	MoBa (Norwegian Mother and Child Cohort)	Weighed Dietary record (4-day)	Fruits + Vegetables	Apple Carrot Fruit juices Tomato Vegetables			g/day	Urine, 24-h	LC-MS after enzymatic hydrolysis	Flavanones	Eriodictyol Hesperetin Naringenin	umol/L	99	Pearson	0.28			< 0.01	Yes	Brantsaeter 2007
405	432	582	All [by supplement]	Participants in the validation study of the MoBa cohort	Norway	NO	MoBa (Norwegian Mother and Child Cohort)	Food Frequency Questionnaire (FFQ)	Citrus fruits				g/day	Urine, 24-h	LC-MS after enzymatic hydrolysis	Flavanones	Eriodictyol Hesperetin Naringenin	umol/L	119	Pearson	0.39			< 0.01	Yes	Brantsaeter 2007
425	452	582	All [by supplement]	Participants in the validation study of the MoBa cohort	Norway	NO	MoBa (Norwegian Mother and Child Cohort)	Food Frequency Questionnaire (FFQ)	Fruits + Vegetables	Apple Carrot Fruit juices Tomato Vegetables		630.0	g/day	Urine, 24-h	LC-MS after enzymatic hydrolysis	Flavanones	Eriodictyol Hesperetin Naringenin	umol/L	119	Pearson	0.15			>= 0.05	No	Brantsaeter 2007
439	470	582	All [by supplement]	Participants in the validation study of the MoBa cohort	Norway	NO	MoBa (Norwegian Mother and Child Cohort)	Weighed Dietary record (4-day)	Citrus fruits				g/day	Urine, 24-h	LC-MS after enzymatic hydrolysis	Flavanones	Eriodictyol Hesperetin Naringenin	umol/L	119	Pearson	0.63			< 0.01	Yes	Brantsaeter 2007
459	490	582	All [by supplement]	Participants in the validation study of the MoBa cohort	Norway	NO	MoBa (Norwegian Mother and Child Cohort)	Weighed Dietary record (4-day)	Fruits + Vegetables	Apple Carrot Fruit juices Tomato Vegetables		540.0	g/day	Urine, 24-h	LC-MS after enzymatic hydrolysis	Flavanones	Eriodictyol Hesperetin Naringenin	umol/L	119	Pearson	0.29			< 0.01	Yes	Brantsaeter 2007
781	816	822	All	Employees at workplaces in Copenhagen area with or without a free-fruit program intervention	Denmark	DK		24-h Dietary recall (1-day)	Fruits	Apple Orange			g/day	Urine, 24-h	HPLC after enzymatic hydrolysis	Flavanones	Eriodictyol Hesperetin Naringenin	ug/day	79	Spearman	0.28	0.13	0.43	< 0.01	Yes	Krogholm 2010
792	817	822	All	Employees at workplaces in Copenhagen area with or without a free-fruit program intervention	Denmark	DK		24-h Dietary recall (1-day)	Citrus fruits	Orange			g/day	Urine, 24-h	HPLC after enzymatic hydrolysis	Flavanones	Eriodictyol Hesperetin Naringenin	ug/day	79	Spearman	0.24	0.09	0.38	< 0.01	Yes	Krogholm 2010
803	818	822	All	Employees at workplaces in Copenhagen area with or without a free-fruit program intervention	Denmark	DK		24-h Dietary recall (1-day)	Vegetables				g/day	Urine, 24-h	HPLC after enzymatic hydrolysis	Flavanones	Eriodictyol Hesperetin Naringenin	ug/day	79	Spearman	0.23	0.08	0.37	< 0.01	Yes	Krogholm 2010
814	819	822	All	Employees at workplaces in Copenhagen area with or without a free-fruit program intervention	Denmark	DK		24-h Dietary recall (1-day)	Fruits + Vegetables	Apple Orange Vegetables			g/day	Urine, 24-h	HPLC after enzymatic hydrolysis	Flavanones	Eriodictyol Hesperetin Naringenin	ug/day	79	Spearman	0.36	0.22	0.49	< 0.01	Yes	Krogholm 2010
825	832	822	All	Employees at workplaces in Copenhagen area with or without a free-fruit program intervention	Denmark	DK		24-h Dietary recall (1-day)	Orange				g/day	Urine, 24-h	HPLC after enzymatic hydrolysis	Flavanones	Eriodictyol Hesperetin Naringenin	ug/day	79	Spearman	0.26	0.11	0.4	< 0.01	Yes	Krogholm 2010
836	820	822	All	Employees at workplaces in Copenhagen area with or without a free-fruit program intervention	Denmark	DK		24-h Dietary recall (1-day)	Apple				g/day	Urine, 24-h	HPLC after enzymatic hydrolysis	Flavanones	Eriodictyol Hesperetin Naringenin	ug/day	79	Spearman	0.2	0.05	0.35	< 0.05	Yes	Krogholm 2010

Reproducibility values

No data available