Fatty acids, n6-polyunsaturated (n6-PUFA)

ID410
NameFatty acids, n6-polyunsaturated (n6-PUFA)
Synonymscis-n6-PUFA; n6-PUFA
StructureThumb
Description
GroupFatty acids
Sub-groupPUFA
Exposure sourceDiet
Use
CAS number
PubChem ID
ChEBI ID
FooDB ID
HMDB ID

Biomarker measurements

Biomarker concentration values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed asPublication
128412832AllMiddle-aged subjects in Southern ChinaChinaCNStudy on soyfood intake and cardiovascular risk factors in GuangzhouRed blood cell membrane, unspecifiedGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)12528.6662.227percentRoot28.7 percentRootCrudeZhang 2010
1634100051AllNunavik Inuit adultsCanadaCANunavik Inuit Health SurveyRed blood cell membrane, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Dihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)
Linoleic acid (LA; cis-18:2n-6)
Osbond acid (cis-22:5n-6)
62725.9percentRoot25.9 percentRootCrudeLucas 2010
197999251AllNear-term pregnant womenCanadaCARed blood cell membrane (Phosphatidylcholine), fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Dihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)
Docosatetraenoic acid (DTA; cis-22:4n-6)
Eicosadienoic acid (cis-20:2n-6)
Linoleic acid (LA; cis-18:2n-6)
Osbond acid (cis-22:5n-6)
10529.81.82percentRoot29.8 percentRootCrudeFriesen 2010
199699261AllNear-term pregnant womenCanadaCARed blood cell membrane (Ethanolamine phosphoglyceride), fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Dihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)
Docosatetraenoic acid (DTA; cis-22:4n-6)
Eicosadienoic acid (cis-20:2n-6)
Linoleic acid (LA; cis-18:2n-6)
Osbond acid (cis-22:5n-6)
10528.92.68percentRoot28.9 percentRootCrudeFriesen 2010
286328642AllControls in a coronary heart disease substudyUnited StatesUSNHS (Nurses' Health Study)Plasma, fasting and non-fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
30641.164.6percentRoot41.2 percentRootCrudeSun 2007
288728882AllControls in a coronary heart disease substudyUnited StatesUSNHS (Nurses' Health Study)Red blood cell, fasting and non-fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
30633.911.79percentRoot33.9 percentRootCrudeSun 2007
3158101891AllParticipants in a dietary validation studyAustraliaAUNambour Skin Cancer StudyPlasma, non-fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
43506.06102.64489.37ug/mL506.1 mg/L489.4 mg/LCrudeMcNaughton 2007
336733652MalesParticipants in a case-cohort studyAustraliaAUMCCS (Melbourne Collaborative Cohort Study)Plasma, fasting and non-fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
204835.32.5percentRoot35.3 percentRootCrudeHodge 2007
340934072FemalesParticipants in a case-cohort studyAustraliaAUMCCS (Melbourne Collaborative Cohort Study)Plasma, fasting and non-fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
239135.72.4percentRoot35.7 percentRootCrudeHodge 2007
422742252Meat high consumers (Meat intake: >285 g/day)Men with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsPlasma, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
1835.52.1mg/100 mL355.0 mg/LCrudeMann 2006
424542432Meat moderate consumers (Meat intake: <260 g/day)Men with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsPlasma, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
6037.02.1mg/100 mL370.0 mg/LCrudeMann 2006
426342612Ovolacto-vegetariansMen with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsPlasma, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
4339.52.6mg/100 mL395.0 mg/LCrudeMann 2006
428142792VegansMen with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsPlasma, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
1840.81.7mg/100 mL408.0 mg/LCrudeMann 2006
452345252AllControls in a case-control study on diet and heart diseaseCosta RicaCRAdipose tissue, buttocksGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Dihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)
Docosatetraenoic acid (DTA; cis-22:4n-6)
Linoleic acid (LA; cis-18:2n-6)
gamma-Linolenic acid (GLA; cis-18:3n-6)
20017.043.56percentRoot17.0 percentRootCrudeBaylin 2005
456245642AllControls in a case-control study on diet and heart diseaseCosta RicaCRPlasma, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Dihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)
Docosatetraenoic acid (DTA; cis-22:4n-6)
Linoleic acid (LA; cis-18:2n-6)
gamma-Linolenic acid (GLA; cis-18:3n-6)
20036.744.66percentRoot36.7 percentRootCrudeBaylin 2005
460146032AllControls in a case-control study on diet and heart diseaseCosta RicaCRWhole blood, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Dihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)
Docosatetraenoic acid (DTA; cis-22:4n-6)
Linoleic acid (LA; cis-18:2n-6)
gamma-Linolenic acid (GLA; cis-18:3n-6)
20035.13.45percentRoot35.1 percentRootCrudeBaylin 2005
487648681MalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Plasma, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
154.00.66mmol/L4000000.0 nmol/LCrudeKuriki 2003
491049021FemalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Plasma, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
794.150.71mmol/L4150000.0 nmol/LCrudeKuriki 2003
494348681MalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Plasma, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
1538.62.74percentRoot38.6 percentRootCrudeKuriki 2003
497549021FemalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Plasma, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
7939.093.17percentRoot39.1 percentRootCrudeKuriki 2003
5470101811AllControls in a case-control study on diet and heart diseaseCosta RicaCRAdipose tissue, buttocksGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Dihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)
Docosatetraenoic acid (DTA; cis-22:4n-6)
Eicosadienoic acid (cis-20:2n-6)
Linoleic acid (LA; cis-18:2n-6)
gamma-Linolenic acid (GLA; cis-18:3n-6)
50315.293.33percentRoot15.3 percentRootCrudeBaylin 2002
5646102351AllPregnant womenMexicoMXA study on PUFAs and foetal neurodevelopmentRed blood cell membrane, unspecifiedGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Dihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)
Docosatetraenoic acid (DTA; cis-22:4n-6)
Eicosadienoic acid (cis-20:2n-6)
Linoleic acid (LA; cis-18:2n-6)
gamma-Linolenic acid (GLA; cis-18:3n-6)
3428.6132.91422.83134.21percentRoot28.6 percentRootCrudeParra 2002
634763452AllObese patients in a clinic from MurciaSpainESAdipose tissue, periumbilical (subcutaneous)GC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Dihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)
Docosatetraenoic acid (DTA; cis-22:4n-6)
Eicosadienoic acid (cis-20:2n-6)
Linoleic acid (LA; cis-18:2n-6)
gamma-Linolenic acid (GLA; cis-18:3n-6)
7616.385.1percentRoot16.4 percentRootCrudeGaraulet 2001
637263702AllObese patients in a clinic from MurciaSpainESAdipose tissue, intraabdominal (perivisceral)GC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Dihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)
Docosatetraenoic acid (DTA; cis-22:4n-6)
Eicosadienoic acid (cis-20:2n-6)
Linoleic acid (LA; cis-18:2n-6)
gamma-Linolenic acid (GLA; cis-18:3n-6)
5716.525.02percentRoot16.5 percentRootCrudeGaraulet 2001
639763952AllObese patients in a clinic from MurciaSpainESAdipose tissue, intraabdominal (omental)GC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Dihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)
Docosatetraenoic acid (DTA; cis-22:4n-6)
Eicosadienoic acid (cis-20:2n-6)
Linoleic acid (LA; cis-18:2n-6)
gamma-Linolenic acid (GLA; cis-18:3n-6)
2417.173.82percentRoot17.2 percentRootCrudeGaraulet 2001
663766312AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
8726.515.333.2percentRoot26.5 percentRootCrudeKobayashi 2001
665166452AllMiddle-aged menJapanJPJPHC Study Cohort IwinterSerum, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
872.41.02.2percentRoot2.4 percentRoot2.2 percentRootCrudeKobayashi 2001
666566592AllMiddle-aged menJapanJPJPHC Study Cohort IsummerSerum, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
872.30.92.1percentRoot2.3 percentRoot2.1 percentRootCrudeKobayashi 2001
802580271AllMiddle-aged women in the Trondheim areaNorwayNOParticipants in a cardiovascular screening by SHUS (National Health Screening Service)Serum, non-fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Dihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)
Docosatetraenoic acid (DTA; cis-22:4n-6)
Eicosadienoic acid (cis-20:2n-6)
Linoleic acid (LA; cis-18:2n-6)
Osbond acid (cis-22:5n-6)
23437.083.33percentRoot37.1 percentRootCrudeHjartaker 1997
805280271AllMiddle-aged women in the Trondheim areaNorwayNOParticipants in a cardiovascular screening by SHUS (National Health Screening Service)Serum, non-fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Dihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)
Docosatetraenoic acid (DTA; cis-22:4n-6)
Eicosadienoic acid (cis-20:2n-6)
Linoleic acid (LA; cis-18:2n-6)
Osbond acid (cis-22:5n-6)
234450.1376.41mg/L450.1 mg/LCrudeHjartaker 1997
18609186152AllWomenUnited StatesUSNYUWHS (New York University Women's Health Study)baselinePlasma, non-fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Dihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)
Docosatetraenoic acid (DTA; cis-22:4n-6)
Eicosadienoic acid (cis-20:2n-6)
Linoleic acid (LA; cis-18:2n-6)
gamma-Linolenic acid (GLA; cis-18:3n-6)
4630.954.86percentRoot31.0 percentRootUnspecifiedZeleniuch-Jacquotte 2000
18641186371AllNursesUnited StatesUSNHS (Nurses' Health Study)baseline; 2 yearsRed blood cell, unspecifiedGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)4024.928.130.0percentRoot28.1 percentRootCrudeKotsopoulos 2010

Intake values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionIntake toolIntake food coverageIntake time coverageIntake assessmentCompoundCompound detailSupplement intakes included?Measurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed asPublication
126812672AllMiddle-aged subjects in Southern ChinaChinaCNStudy on soyfood intake and cardiovascular risk factors in GuangzhouFood Frequency Questionnaire (FFQ)Fatty acids, n6-polyunsaturated (n6-PUFA)12517.7156.992g/day17715.0 mg/dayCrudeZhang 2010
127612752AllMiddle-aged subjects in Southern ChinaChinaCNStudy on soyfood intake and cardiovascular risk factors in GuangzhouDietary record (3-day)Fatty acids, n6-polyunsaturated (n6-PUFA)12519.5174.654g/day19517.0 mg/dayCrudeZhang 2010
291129122AllControls in a coronary heart disease substudyUnited StatesUSNHS (Nurses' Health Study)Food Frequency Questionnaire (FFQ)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
30616.794.21percentRoot16.8 percentRootCrudeSun 2007
3173101901AllParticipants in a dietary validation studyAustraliaAUNambour Skin Cancer StudyFood Frequency Questionnaire (FFQ)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
438.472.937.84g/day8470.0 mg/day7840.0 mg/dayRegressionEnergyMcNaughton 2007
3188101911AllParticipants in a dietary validation studyAustraliaAUNambour Skin Cancer StudyWeighed Dietary record (2-day)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
439.383.788.86g/day9380.0 mg/day8860.0 mg/dayRegressionEnergyMcNaughton 2007
333833362MalesParticipants in a case-cohort studyAustraliaAUMCCS (Melbourne Collaborative Cohort Study)Food Frequency Questionnaire (FFQ)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
204812.35.5g/day12300.0 mg/dayCrudeHodge 2007
335333512MalesParticipants in a case-cohort studyAustraliaAUMCCS (Melbourne Collaborative Cohort Study)Food Frequency Questionnaire (FFQ)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
204813.83.6percentRoot13.8 percentRootCrudeHodge 2007
338133792FemalesParticipants in a case-cohort studyAustraliaAUMCCS (Melbourne Collaborative Cohort Study)Food Frequency Questionnaire (FFQ)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
239110.74.8g/day10700.0 mg/dayCrudeHodge 2007
339533932FemalesParticipants in a case-cohort studyAustraliaAUMCCS (Melbourne Collaborative Cohort Study)Food Frequency Questionnaire (FFQ)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
239114.44.1percentRoot14.4 percentRootCrudeHodge 2007
416041582Meat high consumers (Meat intake: >285 g/day)Men with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsFood Frequency Questionnaire (FFQ)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
1620.7510.49g/day20750.0 mg/dayCrudeMann 2006
417641742Meat moderate consumers (Meat intake: <260 g/day)Men with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsFood Frequency Questionnaire (FFQ)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
5311.075.71g/day11070.0 mg/dayCrudeMann 2006
419341902Ovolacto-vegetariansMen with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsFood Frequency Questionnaire (FFQ)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
4018.468.61g/day18460.0 mg/dayCrudeMann 2006
420942072VegansMen with different diets in Melbourne areaAustraliaAUStudy on diet and thrombotic risk factorcsFood Frequency Questionnaire (FFQ)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
1722.879.59g/day22870.0 mg/dayCrudeMann 2006
448444862AllControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Dihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)
Docosatetraenoic acid (DTA; cis-22:4n-6)
Linoleic acid (LA; cis-18:2n-6)
gamma-Linolenic acid (GLA; cis-18:3n-6)
20019.256.18percentRoot19.3 percentRootRegressionEnergy ?Baylin 2005
485948511MalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Weighed Dietary record (7-day)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
1513057.02854.0mg/day13057.0 mg/dayCrudeKuriki 2003
489348851FemalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Weighed Dietary record (7-day)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
7910907.02869.0mg/day10907.0 mg/dayCrudeKuriki 2003
492748511MalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Weighed Dietary record (7-day)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
1526.523.65percentRoot26.5 percentRootCrudeKuriki 2003
495948851FemalesMiddle-aged dietitiansJapanJPSQFFQ (Japanese Dieticians' Epidemiologic Study)Weighed Dietary record (7-day)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
7923.834.47percentRoot23.8 percentRootCrudeKuriki 2003
551199091AllControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Dihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)
Linoleic acid (LA; cis-18:2n-6)
gamma-Linolenic acid (GLA; cis-18:3n-6)
50317.444.57percentRoot17.4 percentRootCrudeBaylin 2002
555199091AllControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Dihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)
Linoleic acid (LA; cis-18:2n-6)
gamma-Linolenic acid (GLA; cis-18:3n-6)
50312.373.7g/day12370.0 mg/dayRegressionEnergyBaylin 2002
5934100221Quartile 1 (Fish intake: <31 g/day)Adults from GipuzkoaSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Diet History Questionnaire (DHQ)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
2615.089.23g/day15080.0 mg/dayRegressionEnergyAmiano 2001
5942100231Quartile 2 (Fish intake: 32 to 64 g/day)Adults from GipuzkoaSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Diet History Questionnaire (DHQ)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
2414.236.53g/day14230.0 mg/dayRegressionEnergyAmiano 2001
5950100241Quartile 3 (Fish intake: 65 to 115 g/day)Adults from GipuzkoaSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Diet History Questionnaire (DHQ)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
2713.555.93g/day13550.0 mg/dayRegressionEnergyAmiano 2001
5958100251Quartile 4 (Fish intake: >115 g/day)Adults from GipuzkoaSpainESEPIC-Spain (European Prospective Investigation into Cancer and Nutrition)Diet History Questionnaire (DHQ)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
2516.415.29g/day16400.0 mg/dayRegressionEnergyAmiano 2001
641364112AllObese patients in a clinic from MurciaSpainESDietary record (7-day)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
7617.118.38percentRoot17.1 percentRootCrudeGaraulet 2001
660966032AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
8712.26.920.7g/day12200.0 mg/dayCrudeKobayashi 2001
662366172AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
8723.617.232.2percentRoot23.6 percentRootCrudeKobayashi 2001

Correlation values

Reproducibility values

IDMst. IDSubject groupPopulationCountryCountry codeCohortTime definitionBiological specimenExperimental methodBiomarkerBiomarker detailArithmetic meanGeometric meanMedianUnitAdjusted onReproducibility sizeICCICC 95% CI lowerICC 95% CI upperCV% WSCV% BSVAR WSVAR BSPublication
26618582AllWomenUnited StatesUSNYUWHS (New York University Women's Health Study)baseline; 1 year; 2 yearsPlasma, non-fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Dihomo-gamma-linolenic acid (DGLA; cis-20:3n-6)
Docosatetraenoic acid (DTA; cis-22:4n-6)
Eicosadienoic acid (cis-20:2n-6)
Linoleic acid (LA; cis-18:2n-6)
gamma-Linolenic acid (GLA; cis-18:3n-6)
percentRoot460.530.370.69Zeleniuch-Jacquotte 2000
29718641AllNursesUnited StatesUSNHS (Nurses' Health Study)baseline; 2 yearsRed blood cell, unspecifiedGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)28.1percentRoot400.390.170.665.04.1Kotsopoulos 2010
3336637AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
26.5percentRoot870.72Kobayashi 2001