gamma-Linolenic acid (GLA; cis-18:3n-6)

ID433
Namegamma-Linolenic acid (GLA; cis-18:3n-6)
Synonymsall-cis-6,9,12-Octadecatrienoic acid
StructureThumb
Description
GroupFatty acids
Sub-groupPUFA
Exposure sourceDiet
Use
CAS number506-26-3
PubChem ID5280933
ChEBI ID28661
FooDB IDFDB002943
HMDB IDHMDB03073

Biomarker measurements

Biomarker concentration values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed asPublication
3014101571MalesMiddle-aged participants in a nested case-control studyFranceFRSU.VI.MAX (SUpplementation en VItamines et Mineraux AntioXydants)Plasma, fastingGC-FIDgamma-Linolenic acid (GLA; cis-18:3n-6)2760.570.2percentRoot0.6 percentRootCrudeAstorg 2008
3041101581FemalesMiddle-aged participants in a nested case-control studyFranceFRSU.VI.MAX (SUpplementation en VItamines et Mineraux AntioXydants)Plasma, fastingGC-FIDgamma-Linolenic acid (GLA; cis-18:3n-6)2570.470.19percentRoot0.5 percentRootCrudeAstorg 2008
451945233AllControls in a case-control study on diet and heart diseaseCosta RicaCRAdipose tissue, buttocksGC-FIDgamma-Linolenic acid (GLA; cis-18:3n-6)2000.050.02percentRoot0.1 percentRootCrudeBaylin 2005
455845623AllControls in a case-control study on diet and heart diseaseCosta RicaCRPlasma, fastingGC-FIDgamma-Linolenic acid (GLA; cis-18:3n-6)2000.390.16percentRoot0.4 percentRootCrudeBaylin 2005
459746013AllControls in a case-control study on diet and heart diseaseCosta RicaCRWhole blood, fastingGC-FIDgamma-Linolenic acid (GLA; cis-18:3n-6)2000.280.12percentRoot0.3 percentRootCrudeBaylin 2005
547254702AllControls in a case-control study on diet and heart diseaseCosta RicaCRAdipose tissue, buttocksGC-FIDgamma-Linolenic acid (GLA; cis-18:3n-6)4050.140.17percentRoot0.1 percentRootCrudeBaylin 2002
564156462AllPregnant womenMexicoMXA study on PUFAs and foetal neurodevelopmentRed blood cell membrane, unspecifiedGC-FIDgamma-Linolenic acid (GLA; cis-18:3n-6)340.1630.0760.0720.354percentRoot0.2 percentRootCrudeParra 2002
633263473AllObese patients in a clinic from MurciaSpainESAdipose tissue, periumbilical (subcutaneous)GC-FIDgamma-Linolenic acid (GLA; cis-18:3n-6)760.290.4percentRoot0.3 percentRootCrudeGaraulet 2001
635763723AllObese patients in a clinic from MurciaSpainESAdipose tissue, intraabdominal (perivisceral)GC-FIDgamma-Linolenic acid (GLA; cis-18:3n-6)570.250.27percentRoot0.3 percentRootCrudeGaraulet 2001
638263973AllObese patients in a clinic from MurciaSpainESAdipose tissue, intraabdominal (omental)GC-FIDgamma-Linolenic acid (GLA; cis-18:3n-6)240.40.42percentRoot0.4 percentRootCrudeGaraulet 2001
7479100421AllMen in Uppsala county participant in a prospective survey on risk factors for ischemic heart diseaseSwedenSESerum (cholesterol esters), unspecifiedGC-FIDgamma-Linolenic acid (GLA; cis-18:3n-6)660.650.260.21.47percentRoot0.7 percentRootCrudeSmedman 1999
894990502MalesAdults living in CopenhagenDenmarkDKAdipose tissue, buttocksGC-FIDgamma-Linolenic acid (GLA; cis-18:3n-6)230.050.02percentRoot0.1 percentRootCrudeTjonneland 1993
897990532FemalesAdults living in CopenhagenDenmarkDKAdipose tissue, buttocksGC-FIDgamma-Linolenic acid (GLA; cis-18:3n-6)630.050.01percentRoot0.1 percentRootCrudeTjonneland 1993
1014093533AllControls in a study on diet and breast cancer in Boston areaUnited StatesUSAdipose tissue, buttocksGC-FIDgamma-Linolenic acid (GLA; cis-18:3n-6)1150.110.060.00.28percentRoot0.1 percentRootCrudeLondon 1991
18604186093AllWomenUnited StatesUSNYUWHS (New York University Women's Health Study)baselinePlasma, non-fastingGC-FIDgamma-Linolenic acid (GLA; cis-18:3n-6)460.360.12percentRoot0.4 percentRootUnspecifiedZeleniuch-Jacquotte 2000

Intake values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionIntake toolIntake food coverageIntake time coverageIntake assessmentCompoundCompound detailSupplement intakes included?Measurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed asPublication
448044843AllControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)gamma-Linolenic acid (GLA; cis-18:3n-6)2000.030.06percentRoot0.0 percentRootRegressionEnergy ?Baylin 2005
551355112AllControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)gamma-Linolenic acid (GLA; cis-18:3n-6)4050.190.08percentRoot0.2 percentRootCrudeBaylin 2002
555355512AllControls in a case-control study on diet and heart diseaseCosta RicaCRFood Frequency Questionnaire (FFQ)gamma-Linolenic acid (GLA; cis-18:3n-6)4050.140.06g/day138.0 mg/dayRegressionEnergyBaylin 2002

Correlation values

Reproducibility values

IDMst. IDSubject groupPopulationCountryCountry codeCohortTime definitionBiological specimenExperimental methodBiomarkerBiomarker detailArithmetic meanGeometric meanMedianUnitAdjusted onReproducibility sizeICCICC 95% CI lowerICC 95% CI upperCV% WSCV% BSVAR WSVAR BSPublication
26118577AllWomenUnited StatesUSNYUWHS (New York University Women's Health Study)baseline; 1 year; 2 yearsPlasma, non-fastingGC-FIDgamma-Linolenic acid (GLA; cis-18:3n-6)percentRoot460.210.020.4Zeleniuch-Jacquotte 2000