Lutein

ID88
NameLutein
Synonymsall-trans-Lutein
StructureThumb
DescriptionCan coelute with zeaxanthin. This item is only used when "lutein only" is clearly stated, otherwise "Lutein/Zeaxanthin" should be used.
GroupCarotenoids
Sub-groupXanthophylls
Exposure sourceDiet
Use
CAS number127-40-2
PubChem ID5281243
ChEBI ID28838
FooDB IDFDB015471
HMDB IDHMDB03233

Biomarker measurements

Biomarker concentration values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed asPublication
22720Normal weightOverweight and normal weight children from the Hunter regionAustraliaAUPlasma, fastingHPLCLutein380.320.23umol/L320.0 nmol/LCrudeBurrows 2009
22840OverweightOverweight and normal weight children from the Hunter regionAustraliaAUHIKCUPS (Hunter Illawarra Kids Challenge Using Parent Support)Plasma, fastingHPLCLutein200.390.15umol/L390.0 nmol/LCrudeBurrows 2009
22960ObeseOverweight and normal weight children from the Hunter regionAustraliaAUHIKCUPS (Hunter Illawarra Kids Challenge Using Parent Support)Plasma, fastingHPLCLutein350.310.11umol/L310.0 nmol/LCrudeBurrows 2009
23080HIKCUPSOverweight and normal weight children from the Hunter regionAustraliaAUHIKCUPS (Hunter Illawarra Kids Challenge Using Parent Support)Plasma, fastingHPLCLutein550.330.16umol/L330.0 nmol/LCrudeBurrows 2009
239724001Sub-study IParticipants in a dietary validation studyNorwayNOPlasma, fastingHPLCLutein147122.0156.0209.0nmol/L156.0 nmol/LCrudeCarlsen 2011
241824211Sub-study IIParticipants in a dietary validation studyNorwayNOPlasma, fastingHPLCLutein85117.0163.0201.0nmol/L163.0 nmol/LCrudeCarlsen 2011
256525642AllGeneral adult population in BostonUnited StatesUSSerum, fastingHPLCLutein25197.6nmol/L197.6 nmol/LCrudeChung 2009
258225812AllGeneral adult population in BostonUnited StatesUSAdipose tissue, abdomenHPLCLutein25295.8pmol/mg0.3 umol/gDensitySpecimen dry weightChung 2009
260126002AllGeneral adult population in BostonUnited StatesUSAdipose tissue, buttocksHPLCLutein25170.8pmol/mg0.2 umol/gDensitySpecimen dry weightChung 2009
261926182AllGeneral adult population in BostonUnited StatesUSAdipose tissue, thighHPLCLutein25181.3pmol/mg0.2 umol/gDensitySpecimen dry weightChung 2009
399440001MalesParticipants in the EPIC calibration study from nine European countriesFranceFREPIC (European Prospective Investigation into Cancer and Nutrition)Plasma, unspecifiedHPLCLutein15170.38umol/L380.0 nmol/LCrudeAl-Delaimy 2005
400140071FemalesParticipants in the EPIC calibration study from nine European countriesFranceFREPIC (European Prospective Investigation into Cancer and Nutrition)Plasma, unspecifiedHPLCLutein15170.44umol/L440.0 nmol/LCrudeAl-Delaimy 2005
40720All [by gender]Subjects from Golestan ProvinceIran, Islamic Republic ofIRGCS (Golestan Cohort Study)Serum, unspecifiedHPLCLutein1210.310.16umol/L310.0 nmol/LCrudeMalekshah 2006
40790All [by gender]Subjects from Golestan ProvinceIran, Islamic Republic ofIRGCS (Golestan Cohort Study)Serum, unspecifiedHPLCLutein1210.350.2umol/L350.0 nmol/LCrudeMalekshah 2006
44180AllType I diabetic patientsSpainESSerum, fastingHPLCLutein400.210.09umol/L210.0 nmol/LCrudeGranado-Lorencio 2006
46230AllMen from Oerland military flight stationNorwayNOSerum, fastingHPLCLutein1000.1740.0640.168umol/L174.0 nmol/L168.0 nmol/LCrudeAndersen 2005
469547033MalesAdultsNetherlandsNLMORGEN-EPIC projectPlasma, non-fastingHPLCLutein2840.2510.098umol/L251.0 nmol/LCrudeJansen 2004
470747153FemalesAdultsNetherlandsNLMORGEN-EPIC projectPlasma, non-fastingHPLCLutein2870.3040.111umol/L304.0 nmol/LCrudeJansen 2004
726272972AllWomen in the southern part of Mexico CityMexicoMXPlasma, non-fastingHPLCLutein110187.070.0ug/L0.2 mg/LCrudeRomieu 1999
75040All [HPFS]Men living in the Boston areaUnited StatesUSHPFS (Health Professionals Follow-Up Study)Plasma, non-fastingHPLCLutein12115.685.62mg/dL156.8 mg/LCrudeMichaud 1998
75110All [NHS]Women living in the Boston areaUnited StatesUSNHS (Nurses' Health Study)Plasma, non-fastingHPLCLutein18615.386.18mg/dL153.8 mg/LCrudeMichaud 1998
84670Non-smokers femalesAdults at the Arizona Cancer CenterUnited StatesUSbaselinePlasma, unspecifiedHPLCLutein310.180.08umol/L180.0 nmol/LCrudeRitenbaugh 1996
84710Smokers femalesAdults at the Arizona Cancer CenterUnited StatesUSbaselinePlasma, unspecifiedHPLCLutein120.180.07umol/L180.0 nmol/LCrudeRitenbaugh 1996
84750Non-smokers malesAdults at the Arizona Cancer CenterUnited StatesUSbaselinePlasma, unspecifiedHPLCLutein280.20.1umol/L200.0 nmol/LCrudeRitenbaugh 1996
84790Smokers malesAdults at the Arizona Cancer CenterUnited StatesUSbaselinePlasma, unspecifiedHPLCLutein210.140.05umol/L140.0 nmol/LCrudeRitenbaugh 1996
84830AllAdults at the Arizona Cancer CenterUnited StatesUSbaselinePlasma, unspecifiedHPLCLutein920.180.09umol/L180.0 nmol/LCrudeRitenbaugh 1996
92330All [HPFS]Men living in the Boston areaUnited StatesUSHPFS (Health Professionals Follow-Up Study)Plasma, non-fastingHPLCLutein1210.280.1umol/L280.0 nmol/LCrudeAscherio 1992
92430All [NHS]Women living in the Boston areaUnited StatesUSNHS (Nurses' Health Study)Plasma, non-fastingHPLCLutein1860.270.11umol/L270.0 nmol/LCrudeAscherio 1992
18251182532AllHawaii womenUnited StatesUSCohort study of cervical human papillomavirus at the Cancer Research Center of Hawaiibaseline; month 4; month 8; month 12Plasma, fastingHPLCLutein381182.091.022.0167.0820.0ng/mL0.2 mg/L0.2 mg/LCrudeShvetsov 2009

Intake values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionIntake toolIntake food coverageIntake time coverageIntake assessmentCompoundCompound detailSupplement intakes included?Measurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed asPublication
44240AllType I diabetic patientsSpainESFood Frequency Questionnaire (FFQ)Lutein401268.01036.0ug/day1.3 mg/dayCrudeGranado-Lorencio 2006
44300AllType I diabetic patientsSpainESDietary record (3-day)Lutein40717.0805.0ug/day0.7 mg/dayCrudeGranado-Lorencio 2006
75190All [HPFS]Men living in the Boston areaUnited StatesUSHPFS (Health Professionals Follow-Up Study)Food Frequency Questionnaire (FFQ)Lutein1213784.02382.0mg/day3784.0 mg/dayCrudeMichaud 1998
75250All [HPFS]Men living in the Boston areaUnited StatesUSHPFS (Health Professionals Follow-Up Study)Food Frequency Questionnaire (FFQ)Lutein1213803.02038.0mg/day3803.0 mg/dayCrudeMichaud 1998
75310All [NHS]Women living in the Boston areaUnited StatesUSNHS (Nurses' Health Study)Food Frequency Questionnaire (FFQ)Lutein1864438.03674.0mg/day4438.0 mg/dayCrudeMichaud 1998
75370All [NHS]Women living in the Boston areaUnited StatesUSNHS (Nurses' Health Study)Food Frequency Questionnaire (FFQ)Lutein1863984.02690.0mg/day3984.0 mg/dayCrudeMichaud 1998

Correlation values

Reproducibility values

IDMst. IDSubject groupPopulationCountryCountry codeCohortTime definitionBiological specimenExperimental methodBiomarkerBiomarker detailArithmetic meanGeometric meanMedianUnitAdjusted onReproducibility sizeICCICC 95% CI lowerICC 95% CI upperCV% WSCV% BSVAR WSVAR BSPublication
10718251AllHawaii womenUnited StatesUSCohort study of cervical human papillomavirus at the Cancer Research Center of Hawaiibaseline; month 4; month 8; month 12Plasma, fastingHPLCLutein182.0167.0ng/mL3810.690.0020.005Shvetsov 2009
18618496AllWomenUnited StatesUSNYUWHS (New York University Women's Health Study)baseline; 1 year; 2 yearsSerum, non-fastingHPLCLuteinmissing unit480.8van Kappel 2001
61819089AllDutch participants of the EPIC-StudyNetherlandsNLMORGEN-EPIC projectbaseline; 3 yearsPlasma, non-fastingHPLCLuteinnmol/L620.490.320.64Leenders 2013