Kobayashi 2001

ID155
TitleSingle measurement of serum phospholipid fatty acid as a biomarker of specific fatty acid intake in middle-aged Japanese men
AuthorsKobayashi, M.; Sasaki, S.; Kawabata, T.; Hasegawa, K.; Akabane, M.; Tsugane, S.
Year2001
JournalEur J Clin Nutr
Volume55
Issue8
Pages643-650
PubMed ID11477462
DOI10.1038/sj.ejcn.1601194

Subjects

IDParent IDDepthSubject groupPopulationCountryCountry codeEthnicityCohortHealth conditionSmoker proportionSupplement users excluded?GenderFemale proportionSizeAge meanAge SDAge minAge maxAge medianHeight meanHeight SDHeight minHeight maxHeight medianWeight meanWeight SDWeight minWeight maxWeight medianBMI meanBMI SDBMI minBMI maxBMI median
5240AllMiddle-aged menJapanJPAsianJPHC Study Cohort IYesMale0.08757.05.0163.94.866.58.524.82.9

Biomarker concentration values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed as
6640101751AllMiddle-aged menJapanJPJPHC Study Cohort IwinterSerum, fastingGC-FIDFatty acids, saturated (SFA)Palmitic acid (16:0)
Stearic acid (18:0)
8747.33.347.1percentRoot47.3 percentRoot47.1 percentRootCrude
664166402AllMiddle-aged menJapanJPJPHC Study Cohort IwinterSerum, fastingGC-FIDPalmitic acid (16:0)8728.53.128.7percentRoot28.5 percentRoot28.7 percentRootCrude
664266402AllMiddle-aged menJapanJPJPHC Study Cohort IwinterSerum, fastingGC-FIDStearic acid (18:0)8715.01.715.0percentRoot15.0 percentRoot15.0 percentRootCrude
6643101751AllMiddle-aged menJapanJPJPHC Study Cohort IwinterSerum, fastingGC-FIDFatty acids, monounsaturated (MUFA)Oleic acid (cis-18:1n-9)
8713.72.013.4percentRoot13.7 percentRoot13.4 percentRootCrude
664466432AllMiddle-aged menJapanJPJPHC Study Cohort IwinterSerum, fastingGC-FIDOleic acid (cis-18:1n-9)878.81.58.8percentRoot8.8 percentRoot8.8 percentRootCrude
6645101751AllMiddle-aged menJapanJPJPHC Study Cohort IwinterSerum, fastingGC-FIDFatty acids, polyunsaturated (PUFA)Arachidonic acid (AA; cis-20:4n-6)
DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
Linoleic acid (LA; cis-18:2n-6)
alpha-Linolenic acid (ALA; cis-18:3n-3)
8739.04.238.9percentRoot39.0 percentRoot38.9 percentRootCrude
664666452AllMiddle-aged menJapanJPJPHC Study Cohort IwinterSerum, fastingGC-FIDFatty acids, n3-polyunsaturated (n3-PUFA)DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
alpha-Linolenic acid (ALA; cis-18:3n-3)
872.10.92.0percentRoot2.1 percentRoot2.0 percentRootCrude
664766463AllMiddle-aged menJapanJPJPHC Study Cohort IwinterSerum, fastingGC-FIDalpha-Linolenic acid (ALA; cis-18:3n-3)870.20.20.2percentRoot0.2 percentRoot0.2 percentRootCrude
664866463AllMiddle-aged menJapanJPJPHC Study Cohort IwinterSerum, fastingGC-FIDEPA (cis-20:5n-3)873.71.73.5percentRoot3.7 percentRoot3.5 percentRootCrude
664966463AllMiddle-aged menJapanJPJPHC Study Cohort IwinterSerum, fastingGC-FIDDPA (cis-22:5n-3)871.20.41.2percentRoot1.2 percentRoot1.2 percentRootCrude
665066463AllMiddle-aged menJapanJPJPHC Study Cohort IwinterSerum, fastingGC-FIDDHA (cis-22:6n-3)877.21.96.9percentRoot7.2 percentRoot6.9 percentRootCrude
665166452AllMiddle-aged menJapanJPJPHC Study Cohort IwinterSerum, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
872.41.02.2percentRoot2.4 percentRoot2.2 percentRootCrude
665266513AllMiddle-aged menJapanJPJPHC Study Cohort IwinterSerum, fastingGC-FIDLinoleic acid (LA; cis-18:2n-6)8717.73.617.8percentRoot17.7 percentRoot17.8 percentRootCrude
665366513AllMiddle-aged menJapanJPJPHC Study Cohort IwinterSerum, fastingGC-FIDArachidonic acid (AA; cis-20:4n-6)876.41.66.3percentRoot6.4 percentRoot6.3 percentRootCrude
6654101761AllMiddle-aged menJapanJPJPHC Study Cohort IsummerSerum, fastingGC-FIDFatty acids, saturated (SFA)Palmitic acid (16:0)
Stearic acid (18:0)
8747.83.547.3percentRoot47.8 percentRoot47.3 percentRootCrude
665566542AllMiddle-aged menJapanJPJPHC Study Cohort IsummerSerum, fastingGC-FIDPalmitic acid (16:0)8728.92.829.0percentRoot28.9 percentRoot29.0 percentRootCrude
665666542AllMiddle-aged menJapanJPJPHC Study Cohort IsummerSerum, fastingGC-FIDStearic acid (18:0)8715.22.115.0percentRoot15.2 percentRoot15.0 percentRootCrude
6657101761AllMiddle-aged menJapanJPJPHC Study Cohort IsummerSerum, fastingGC-FIDFatty acids, monounsaturated (MUFA)Oleic acid (cis-18:1n-9)
8713.51.813.3percentRoot13.5 percentRoot13.3 percentRootCrude
665866572AllMiddle-aged menJapanJPJPHC Study Cohort IsummerSerum, fastingGC-FIDOleic acid (cis-18:1n-9)878.81.58.5percentRoot8.8 percentRoot8.5 percentRootCrude
6659101761AllMiddle-aged menJapanJPJPHC Study Cohort IsummerSerum, fastingGC-FIDFatty acids, polyunsaturated (PUFA)Arachidonic acid (AA; cis-20:4n-6)
DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
Linoleic acid (LA; cis-18:2n-6)
alpha-Linolenic acid (ALA; cis-18:3n-3)
8738.74.039.2percentRoot38.7 percentRoot39.2 percentRootCrude
666066592AllMiddle-aged menJapanJPJPHC Study Cohort IsummerSerum, fastingGC-FIDFatty acids, n3-polyunsaturated (n3-PUFA)DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
alpha-Linolenic acid (ALA; cis-18:3n-3)
872.10.82.1percentRoot2.1 percentRoot2.1 percentRootCrude
666166603AllMiddle-aged menJapanJPJPHC Study Cohort IsummerSerum, fastingGC-FIDalpha-Linolenic acid (ALA; cis-18:3n-3)870.20.20.2percentRoot0.2 percentRoot0.2 percentRootCrude
666266603AllMiddle-aged menJapanJPJPHC Study Cohort IsummerSerum, fastingGC-FIDEPA (cis-20:5n-3)873.71.93.2percentRoot3.7 percentRoot3.2 percentRootCrude
666366603AllMiddle-aged menJapanJPJPHC Study Cohort IsummerSerum, fastingGC-FIDDPA (cis-22:5n-3)871.20.41.2percentRoot1.2 percentRoot1.2 percentRootCrude
666466603AllMiddle-aged menJapanJPJPHC Study Cohort IsummerSerum, fastingGC-FIDDHA (cis-22:6n-3)877.41.97.2percentRoot7.4 percentRoot7.2 percentRootCrude
666566592AllMiddle-aged menJapanJPJPHC Study Cohort IsummerSerum, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
872.30.92.1percentRoot2.3 percentRoot2.1 percentRootCrude
666666653AllMiddle-aged menJapanJPJPHC Study Cohort IsummerSerum, fastingGC-FIDLinoleic acid (LA; cis-18:2n-6)8716.93.317.0percentRoot16.9 percentRoot17.0 percentRootCrude
666766653AllMiddle-aged menJapanJPJPHC Study Cohort IsummerSerum, fastingGC-FIDArachidonic acid (AA; cis-20:4n-6)876.41.76.1percentRoot6.4 percentRoot6.1 percentRootCrude
6626101741AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDFatty acids, saturated (SFA)Palmitic acid (16:0)
Stearic acid (18:0)
8747.642.258.9percentRoot47.6 percentRootCrude
662766262AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDPalmitic acid (16:0)8728.723.236.9percentRoot28.7 percentRootCrude
662866262AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDStearic acid (18:0)8715.111.720.8percentRoot15.1 percentRootCrude
6629101741AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDFatty acids, monounsaturated (MUFA)Oleic acid (cis-18:1n-9)
8713.610.318.4percentRoot13.6 percentRootCrude
663066292AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDOleic acid (cis-18:1n-9)878.86.312.6percentRoot8.8 percentRootCrude
6631101741AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDFatty acids, polyunsaturated (PUFA)Arachidonic acid (AA; cis-20:4n-6)
DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
Linoleic acid (LA; cis-18:2n-6)
alpha-Linolenic acid (ALA; cis-18:3n-3)
8738.928.245.8percentRoot38.9 percentRootCrude
663266312AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDFatty acids, n3-polyunsaturated (n3-PUFA)DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
alpha-Linolenic acid (ALA; cis-18:3n-3)
8712.47.020.2percentRoot12.4 percentRootCrude
663366323AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDalpha-Linolenic acid (ALA; cis-18:3n-3)870.20.11.2percentRoot0.2 percentRootCrude
663466323AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDEPA (cis-20:5n-3)873.71.27.3percentRoot3.7 percentRootCrude
663566323AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDDPA (cis-22:5n-3)871.20.52.2percentRoot1.2 percentRootCrude
663666323AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDDHA (cis-22:6n-3)877.34.111.3percentRoot7.3 percentRootCrude
663766312AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
8726.515.333.2percentRoot26.5 percentRootCrude
663866373AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDLinoleic acid (LA; cis-18:2n-6)8717.39.324.3percentRoot17.3 percentRootCrude
663966373AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDArachidonic acid (AA; cis-20:4n-6)876.43.79.6percentRoot6.4 percentRootCrude

Intake values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionIntake toolIntake food coverageIntake time coverageIntake assessmentCompoundCompound detailSupplement intakes included?Measurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed as
65970AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Energy879.91.9MJ/day2364.6 kcal/dayCrude
6598101771AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, saturated (SFA)Palmitic acid (16:0)
Stearic acid (18:0)
8716.19.724.4g/day16100.0 mg/dayCrude
659965982AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Palmitic acid (16:0)879.96.414.1g/day9900.0 mg/dayCrude
660065982AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Stearic acid (18:0)873.62.25.8g/day3600.0 mg/dayCrude
6601101771AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, monounsaturated (MUFA)Oleic acid (cis-18:1n-9)
8719.612.728.6g/day19600.0 mg/dayCrude
660266012AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Oleic acid (cis-18:1n-9)8717.010.525.1g/day16761.3 mg/dayCrude
6603101771AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, polyunsaturated (PUFA)Arachidonic acid (AA; cis-20:4n-6)
DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
Linoleic acid (LA; cis-18:2n-6)
alpha-Linolenic acid (ALA; cis-18:3n-3)
8715.89.226.6g/day15800.0 mg/dayCrude
660466032AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, n3-polyunsaturated (n3-PUFA)DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
alpha-Linolenic acid (ALA; cis-18:3n-3)
873.51.68.7g/day3500.0 mg/dayCrude
660566043AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)alpha-Linolenic acid (ALA; cis-18:3n-3)No871.81.03.1g/day1800.0 mg/dayCrude
660666043AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)EPA (cis-20:5n-3)No870.60.12.1g/day591.6 mg/dayCrude
660766043AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)DPA (cis-22:5n-3)No870.10.00.4g/day98.6 mg/dayCrude
660866043AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)DHA (cis-22:6n-3)No870.90.22.7g/day887.4 mg/dayCrude
660966032AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
8712.26.920.7g/day12200.0 mg/dayCrude
661066093AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Linoleic acid (LA; cis-18:2n-6)8712.26.820.5g/day12200.0 mg/dayCrude
661166093AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Arachidonic acid (AA; cis-20:4n-6)870.22.05.7g/day197.2 mg/dayCrude
6612101771AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, saturated (SFA)Palmitic acid (16:0)
Stearic acid (18:0)
8730.823.039.3percentRoot30.8 percentRootCrude
661366122AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Palmitic acid (16:0)8719.115.322.5percentRoot19.1 percentRootCrude
661466122AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Stearic acid (18:0)877.05.38.9percentRoot7.0 percentRootCrude
6615101771AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, monounsaturated (MUFA)Oleic acid (cis-18:1n-9)
8737.733.742.9percentRoot37.7 percentRootCrude
661666152AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Oleic acid (cis-18:1n-9)8732.727.837.2percentRoot32.7 percentRootCrude
6617101771AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, polyunsaturated (PUFA)Arachidonic acid (AA; cis-20:4n-6)
DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
Linoleic acid (LA; cis-18:2n-6)
alpha-Linolenic acid (ALA; cis-18:3n-3)
8730.621.239.3percentRoot30.6 percentRootCrude
661866172AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, n3-polyunsaturated (n3-PUFA)DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
alpha-Linolenic acid (ALA; cis-18:3n-3)
876.84.011.4percentRoot6.8 percentRootCrude
661966183AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)alpha-Linolenic acid (ALA; cis-18:3n-3)No873.62.04.9percentRoot3.6 percentRootCrude
662066183AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)EPA (cis-20:5n-3)No871.10.22.8percentRoot1.1 percentRootCrude
662166183AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)DPA (cis-22:5n-3)No870.30.10.6percentRoot0.3 percentRootCrude
662266183AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)DHA (cis-22:6n-3)No871.70.53.5percentRoot1.7 percentRootCrude
662366172AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
8723.617.232.2percentRoot23.6 percentRootCrude
662466233AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Linoleic acid (LA; cis-18:2n-6)8723.517.032.4percentRoot23.5 percentRootCrude
662566233AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Arachidonic acid (AA; cis-20:4n-6)870.40.20.6percentRoot0.4 percentRootCrude
101780AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fats8759.310.7g/day59300.0 mg/dayCrude

Correlation values

IDIntake IDExcretion IDSubject groupPopulationCountryCountry codeCohortIntake Time definitionIntake assessmentIntakeIntake detailSupplement intakes included?Intake Arithmetic meanIntake Geometric meanIntake MedianIntake UnitIntake Adjusted onBiomarker Time definitionBiological specimenBiomarker Experimental methodBiomarkerBiomarker detailBiomarker Arithmetic meanBiomarker Geometric meanBiomarker MedianBiomarker UnitBiomarker Adjusted onCorrelation sizeCorrelation typeCorrelation valueCorrelation 95% CI lowerCorrelation 95% CI upperCorrelation p-valueSignificant?Measurement adjustmentDeattenuated?Covariates
611165986626AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, saturated (SFA)Palmitic acid (16:0)
Stearic acid (18:0)
16.1g/daywinter; summerSerum, fastingGC-FIDFatty acids, saturated (SFA)Palmitic acid (16:0)
Stearic acid (18:0)
47.6percentRoot87Pearson-0.02>= 0.05NoNo
613965986626AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, saturated (SFA)Palmitic acid (16:0)
Stearic acid (18:0)
16.1g/daywinter; summerSerum, fastingGC-FIDFatty acids, saturated (SFA)Palmitic acid (16:0)
Stearic acid (18:0)
47.6percentRoot87Pearson-0.03>= 0.05NoYes
611265996627AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Palmitic acid (16:0)9.9g/daywinter; summerSerum, fastingGC-FIDPalmitic acid (16:0)28.7percentRoot87Pearson-0.18>= 0.05NoNo
614065996627AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Palmitic acid (16:0)9.9g/daywinter; summerSerum, fastingGC-FIDPalmitic acid (16:0)28.7percentRoot87Pearson-0.2>= 0.05NoYes
611366006628AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Stearic acid (18:0)3.6g/daywinter; summerSerum, fastingGC-FIDStearic acid (18:0)15.1percentRoot87Pearson0.14>= 0.05NoNo
614166006628AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Stearic acid (18:0)3.6g/daywinter; summerSerum, fastingGC-FIDStearic acid (18:0)15.1percentRoot87Pearson0.15>= 0.05NoYes
611466016629AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, monounsaturated (MUFA)Oleic acid (cis-18:1n-9)
19.6g/daywinter; summerSerum, fastingGC-FIDFatty acids, monounsaturated (MUFA)Oleic acid (cis-18:1n-9)
13.6percentRoot87Pearson-0.02>= 0.05NoNo
614266016629AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, monounsaturated (MUFA)Oleic acid (cis-18:1n-9)
19.6g/daywinter; summerSerum, fastingGC-FIDFatty acids, monounsaturated (MUFA)Oleic acid (cis-18:1n-9)
13.6percentRoot87Pearson-0.02>= 0.05NoYes
611566026630AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Oleic acid (cis-18:1n-9)17.0g/daywinter; summerSerum, fastingGC-FIDOleic acid (cis-18:1n-9)8.8percentRoot87Pearson-0.03>= 0.05NoNo
614366026630AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Oleic acid (cis-18:1n-9)17.0g/daywinter; summerSerum, fastingGC-FIDOleic acid (cis-18:1n-9)8.8percentRoot87Pearson-0.04>= 0.05NoYes
611666036631AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, polyunsaturated (PUFA)Arachidonic acid (AA; cis-20:4n-6)
DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
Linoleic acid (LA; cis-18:2n-6)
alpha-Linolenic acid (ALA; cis-18:3n-3)
15.8g/daywinter; summerSerum, fastingGC-FIDFatty acids, polyunsaturated (PUFA)Arachidonic acid (AA; cis-20:4n-6)
DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
Linoleic acid (LA; cis-18:2n-6)
alpha-Linolenic acid (ALA; cis-18:3n-3)
38.9percentRoot87Pearson0.09>= 0.05NoNo
614466036631AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, polyunsaturated (PUFA)Arachidonic acid (AA; cis-20:4n-6)
DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
Linoleic acid (LA; cis-18:2n-6)
alpha-Linolenic acid (ALA; cis-18:3n-3)
15.8g/daywinter; summerSerum, fastingGC-FIDFatty acids, polyunsaturated (PUFA)Arachidonic acid (AA; cis-20:4n-6)
DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
Linoleic acid (LA; cis-18:2n-6)
alpha-Linolenic acid (ALA; cis-18:3n-3)
38.9percentRoot87Pearson0.1>= 0.05NoYes
611766046632AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, n3-polyunsaturated (n3-PUFA)DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
alpha-Linolenic acid (ALA; cis-18:3n-3)
3.5g/daywinter; summerSerum, fastingGC-FIDFatty acids, n3-polyunsaturated (n3-PUFA)DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
alpha-Linolenic acid (ALA; cis-18:3n-3)
12.4percentRoot87Pearson0.39< 0.001YesNo
614566046632AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, n3-polyunsaturated (n3-PUFA)DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
alpha-Linolenic acid (ALA; cis-18:3n-3)
3.5g/daywinter; summerSerum, fastingGC-FIDFatty acids, n3-polyunsaturated (n3-PUFA)DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
alpha-Linolenic acid (ALA; cis-18:3n-3)
12.4percentRoot87Pearson0.45< 0.001YesYes
611866056633AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)alpha-Linolenic acid (ALA; cis-18:3n-3)No1.8g/daywinter; summerSerum, fastingGC-FIDalpha-Linolenic acid (ALA; cis-18:3n-3)0.2percentRoot87Pearson-0.02>= 0.05NoNo
614666056633AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)alpha-Linolenic acid (ALA; cis-18:3n-3)No1.8g/daywinter; summerSerum, fastingGC-FIDalpha-Linolenic acid (ALA; cis-18:3n-3)0.2percentRoot87Pearson-0.02>= 0.05NoYes
611966066634AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)EPA (cis-20:5n-3)No0.6g/daywinter; summerSerum, fastingGC-FIDEPA (cis-20:5n-3)3.7percentRoot87Pearson0.66< 0.001YesNo
614766066634AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)EPA (cis-20:5n-3)No0.6g/daywinter; summerSerum, fastingGC-FIDEPA (cis-20:5n-3)3.7percentRoot87Pearson0.77< 0.001YesYes
612066076635AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)DPA (cis-22:5n-3)No0.1g/daywinter; summerSerum, fastingGC-FIDDPA (cis-22:5n-3)1.2percentRoot87Pearson0.38< 0.001YesNo
614866076635AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)DPA (cis-22:5n-3)No0.1g/daywinter; summerSerum, fastingGC-FIDDPA (cis-22:5n-3)1.2percentRoot87Pearson0.46< 0.001YesYes
612166086636AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)DHA (cis-22:6n-3)No0.9g/daywinter; summerSerum, fastingGC-FIDDHA (cis-22:6n-3)7.3percentRoot87Pearson0.36< 0.001YesNo
614966086636AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)DHA (cis-22:6n-3)No0.9g/daywinter; summerSerum, fastingGC-FIDDHA (cis-22:6n-3)7.3percentRoot87Pearson0.43< 0.001YesYes
612266096637AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
12.2g/daywinter; summerSerum, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
26.5percentRoot87Pearson0.25< 0.05YesNo
615066096637AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
12.2g/daywinter; summerSerum, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
26.5percentRoot87Pearson0.28< 0.01YesYes
612366106638AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Linoleic acid (LA; cis-18:2n-6)12.2g/daywinter; summerSerum, fastingGC-FIDLinoleic acid (LA; cis-18:2n-6)17.3percentRoot87Pearson0.2>= 0.05NoNo
615166106638AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Linoleic acid (LA; cis-18:2n-6)12.2g/daywinter; summerSerum, fastingGC-FIDLinoleic acid (LA; cis-18:2n-6)17.3percentRoot87Pearson0.23< 0.05YesYes
612466116639AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Arachidonic acid (AA; cis-20:4n-6)0.2g/daywinter; summerSerum, fastingGC-FIDArachidonic acid (AA; cis-20:4n-6)6.4percentRoot87Pearson-0.22< 0.05YesNo
615266116639AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Arachidonic acid (AA; cis-20:4n-6)0.2g/daywinter; summerSerum, fastingGC-FIDArachidonic acid (AA; cis-20:4n-6)6.4percentRoot87Pearson-0.27< 0.05YesYes
612566126626AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, saturated (SFA)Palmitic acid (16:0)
Stearic acid (18:0)
30.8percentRootwinter; summerSerum, fastingGC-FIDFatty acids, saturated (SFA)Palmitic acid (16:0)
Stearic acid (18:0)
47.6percentRoot87Pearson-0.08>= 0.05NoNo
615366126626AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, saturated (SFA)Palmitic acid (16:0)
Stearic acid (18:0)
30.8percentRootwinter; summerSerum, fastingGC-FIDFatty acids, saturated (SFA)Palmitic acid (16:0)
Stearic acid (18:0)
47.6percentRoot87Pearson-0.09>= 0.05NoYes
616766126640AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, saturated (SFA)Palmitic acid (16:0)
Stearic acid (18:0)
30.8percentRootwinterSerum, fastingGC-FIDFatty acids, saturated (SFA)Palmitic acid (16:0)
Stearic acid (18:0)
47.347.1percentRoot87Pearson-0.11>= 0.05No
618166126654AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, saturated (SFA)Palmitic acid (16:0)
Stearic acid (18:0)
30.8percentRootsummerSerum, fastingGC-FIDFatty acids, saturated (SFA)Palmitic acid (16:0)
Stearic acid (18:0)
47.847.3percentRoot87Pearson-0.02>= 0.05No
612666136627AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Palmitic acid (16:0)19.1percentRootwinter; summerSerum, fastingGC-FIDPalmitic acid (16:0)28.7percentRoot87Pearson-0.01>= 0.05NoNo
615466136627AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Palmitic acid (16:0)19.1percentRootwinter; summerSerum, fastingGC-FIDPalmitic acid (16:0)28.7percentRoot87Pearson-0.01>= 0.05NoYes
616866136641AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Palmitic acid (16:0)19.1percentRootwinterSerum, fastingGC-FIDPalmitic acid (16:0)28.528.7percentRoot87Pearson-0.05>= 0.05No
618266136655AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Palmitic acid (16:0)19.1percentRootsummerSerum, fastingGC-FIDPalmitic acid (16:0)28.929.0percentRoot87Pearson0.04>= 0.05No
612766146628AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Stearic acid (18:0)7.0percentRootwinter; summerSerum, fastingGC-FIDStearic acid (18:0)15.1percentRoot87Pearson-0.02>= 0.05NoNo
615566146628AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Stearic acid (18:0)7.0percentRootwinter; summerSerum, fastingGC-FIDStearic acid (18:0)15.1percentRoot87Pearson-0.03>= 0.05NoYes
616966146642AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Stearic acid (18:0)7.0percentRootwinterSerum, fastingGC-FIDStearic acid (18:0)15.015.0percentRoot87Pearson-0.01>= 0.05No
618366146656AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Stearic acid (18:0)7.0percentRootsummerSerum, fastingGC-FIDStearic acid (18:0)15.215.0percentRoot87Pearson-0.02>= 0.05No
612866156629AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, monounsaturated (MUFA)Oleic acid (cis-18:1n-9)
37.7percentRootwinter; summerSerum, fastingGC-FIDFatty acids, monounsaturated (MUFA)Oleic acid (cis-18:1n-9)
13.6percentRoot87Pearson0.39< 0.001YesNo
615666156629AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, monounsaturated (MUFA)Oleic acid (cis-18:1n-9)
37.7percentRootwinter; summerSerum, fastingGC-FIDFatty acids, monounsaturated (MUFA)Oleic acid (cis-18:1n-9)
13.6percentRoot87Pearson0.52< 0.001YesYes
617066156643AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, monounsaturated (MUFA)Oleic acid (cis-18:1n-9)
37.7percentRootwinterSerum, fastingGC-FIDFatty acids, monounsaturated (MUFA)Oleic acid (cis-18:1n-9)
13.713.4percentRoot87Pearson0.45< 0.001Yes
618466156657AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, monounsaturated (MUFA)Oleic acid (cis-18:1n-9)
37.7percentRootsummerSerum, fastingGC-FIDFatty acids, monounsaturated (MUFA)Oleic acid (cis-18:1n-9)
13.513.3percentRoot87Pearson0.2>= 0.05No
612966166630AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Oleic acid (cis-18:1n-9)32.7percentRootwinter; summerSerum, fastingGC-FIDOleic acid (cis-18:1n-9)8.8percentRoot87Pearson0.35< 0.001YesNo
615766166630AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Oleic acid (cis-18:1n-9)32.7percentRootwinter; summerSerum, fastingGC-FIDOleic acid (cis-18:1n-9)8.8percentRoot87Pearson0.42< 0.001YesYes
617166166644AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Oleic acid (cis-18:1n-9)32.7percentRootwinterSerum, fastingGC-FIDOleic acid (cis-18:1n-9)8.88.8percentRoot87Pearson0.41< 0.001Yes
618566166658AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Oleic acid (cis-18:1n-9)32.7percentRootsummerSerum, fastingGC-FIDOleic acid (cis-18:1n-9)8.88.5percentRoot87Pearson0.17>= 0.05No
613066176631AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, polyunsaturated (PUFA)Arachidonic acid (AA; cis-20:4n-6)
DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
Linoleic acid (LA; cis-18:2n-6)
alpha-Linolenic acid (ALA; cis-18:3n-3)
30.6percentRootwinter; summerSerum, fastingGC-FIDFatty acids, polyunsaturated (PUFA)Arachidonic acid (AA; cis-20:4n-6)
DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
Linoleic acid (LA; cis-18:2n-6)
alpha-Linolenic acid (ALA; cis-18:3n-3)
38.9percentRoot87Pearson0.09>= 0.05NoNo
615866176631AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, polyunsaturated (PUFA)Arachidonic acid (AA; cis-20:4n-6)
DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
Linoleic acid (LA; cis-18:2n-6)
alpha-Linolenic acid (ALA; cis-18:3n-3)
30.6percentRootwinter; summerSerum, fastingGC-FIDFatty acids, polyunsaturated (PUFA)Arachidonic acid (AA; cis-20:4n-6)
DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
Linoleic acid (LA; cis-18:2n-6)
alpha-Linolenic acid (ALA; cis-18:3n-3)
38.9percentRoot87Pearson0.1>= 0.05NoYes
617266176645AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, polyunsaturated (PUFA)Arachidonic acid (AA; cis-20:4n-6)
DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
Linoleic acid (LA; cis-18:2n-6)
alpha-Linolenic acid (ALA; cis-18:3n-3)
30.6percentRootwinterSerum, fastingGC-FIDFatty acids, polyunsaturated (PUFA)Arachidonic acid (AA; cis-20:4n-6)
DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
Linoleic acid (LA; cis-18:2n-6)
alpha-Linolenic acid (ALA; cis-18:3n-3)
39.038.9percentRoot87Pearson0.09>= 0.05No
618666176659AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, polyunsaturated (PUFA)Arachidonic acid (AA; cis-20:4n-6)
DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
Linoleic acid (LA; cis-18:2n-6)
alpha-Linolenic acid (ALA; cis-18:3n-3)
30.6percentRootsummerSerum, fastingGC-FIDFatty acids, polyunsaturated (PUFA)Arachidonic acid (AA; cis-20:4n-6)
DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
Linoleic acid (LA; cis-18:2n-6)
alpha-Linolenic acid (ALA; cis-18:3n-3)
38.739.2percentRoot87Pearson0.06>= 0.05No
613166186632AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, n3-polyunsaturated (n3-PUFA)DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
alpha-Linolenic acid (ALA; cis-18:3n-3)
6.8percentRootwinter; summerSerum, fastingGC-FIDFatty acids, n3-polyunsaturated (n3-PUFA)DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
alpha-Linolenic acid (ALA; cis-18:3n-3)
12.4percentRoot87Pearson0.66< 0.001YesNo
615966186632AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, n3-polyunsaturated (n3-PUFA)DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
alpha-Linolenic acid (ALA; cis-18:3n-3)
6.8percentRootwinter; summerSerum, fastingGC-FIDFatty acids, n3-polyunsaturated (n3-PUFA)DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
alpha-Linolenic acid (ALA; cis-18:3n-3)
12.4percentRoot87Pearson0.76< 0.001YesYes
617366186646AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, n3-polyunsaturated (n3-PUFA)DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
alpha-Linolenic acid (ALA; cis-18:3n-3)
6.8percentRootwinterSerum, fastingGC-FIDFatty acids, n3-polyunsaturated (n3-PUFA)DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
alpha-Linolenic acid (ALA; cis-18:3n-3)
2.12.0percentRoot87Pearson0.61< 0.001Yes
618766186660AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, n3-polyunsaturated (n3-PUFA)DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
alpha-Linolenic acid (ALA; cis-18:3n-3)
6.8percentRootsummerSerum, fastingGC-FIDFatty acids, n3-polyunsaturated (n3-PUFA)DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
alpha-Linolenic acid (ALA; cis-18:3n-3)
2.12.1percentRoot87Pearson0.6< 0.001Yes
613266196633AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)alpha-Linolenic acid (ALA; cis-18:3n-3)No3.6percentRootwinter; summerSerum, fastingGC-FIDalpha-Linolenic acid (ALA; cis-18:3n-3)0.2percentRoot87Pearson0.07>= 0.05NoNo
616066196633AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)alpha-Linolenic acid (ALA; cis-18:3n-3)No3.6percentRootwinter; summerSerum, fastingGC-FIDalpha-Linolenic acid (ALA; cis-18:3n-3)0.2percentRoot87Pearson0.09>= 0.05NoYes
617466196647AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)alpha-Linolenic acid (ALA; cis-18:3n-3)No3.6percentRootwinterSerum, fastingGC-FIDalpha-Linolenic acid (ALA; cis-18:3n-3)0.20.2percentRoot87Pearson0.05>= 0.05No
618866196661AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)alpha-Linolenic acid (ALA; cis-18:3n-3)No3.6percentRootsummerSerum, fastingGC-FIDalpha-Linolenic acid (ALA; cis-18:3n-3)0.20.2percentRoot87Pearson0.05>= 0.05No
613366206634AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)EPA (cis-20:5n-3)No1.1percentRootwinter; summerSerum, fastingGC-FIDEPA (cis-20:5n-3)3.7percentRoot87Pearson0.75< 0.001YesNo
616166206634AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)EPA (cis-20:5n-3)No1.1percentRootwinter; summerSerum, fastingGC-FIDEPA (cis-20:5n-3)3.7percentRoot87Pearson0.89< 0.001YesYes
617566206648AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)EPA (cis-20:5n-3)No1.1percentRootwinterSerum, fastingGC-FIDEPA (cis-20:5n-3)3.73.5percentRoot87Pearson0.7< 0.001Yes
618966206662AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)EPA (cis-20:5n-3)No1.1percentRootsummerSerum, fastingGC-FIDEPA (cis-20:5n-3)3.73.2percentRoot87Pearson0.63< 0.001Yes
613466216635AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)DPA (cis-22:5n-3)No0.3percentRootwinter; summerSerum, fastingGC-FIDDPA (cis-22:5n-3)1.2percentRoot87Pearson0.49< 0.001YesNo
616266216635AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)DPA (cis-22:5n-3)No0.3percentRootwinter; summerSerum, fastingGC-FIDDPA (cis-22:5n-3)1.2percentRoot87Pearson0.54< 0.001YesYes
617666216649AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)DPA (cis-22:5n-3)No0.3percentRootwinterSerum, fastingGC-FIDDPA (cis-22:5n-3)1.21.2percentRoot87Pearson0.45< 0.001Yes
619066216663AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)DPA (cis-22:5n-3)No0.3percentRootsummerSerum, fastingGC-FIDDPA (cis-22:5n-3)1.21.2percentRoot87Pearson0.46< 0.001Yes
613566226636AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)DHA (cis-22:6n-3)No1.7percentRootwinter; summerSerum, fastingGC-FIDDHA (cis-22:6n-3)7.3percentRoot87Pearson0.5< 0.001YesNo
616366226636AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)DHA (cis-22:6n-3)No1.7percentRootwinter; summerSerum, fastingGC-FIDDHA (cis-22:6n-3)7.3percentRoot87Pearson0.61< 0.001YesYes
617766226650AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)DHA (cis-22:6n-3)No1.7percentRootwinterSerum, fastingGC-FIDDHA (cis-22:6n-3)7.26.9percentRoot87Pearson0.44< 0.001Yes
619166226664AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)DHA (cis-22:6n-3)No1.7percentRootsummerSerum, fastingGC-FIDDHA (cis-22:6n-3)7.47.2percentRoot87Pearson0.46< 0.001Yes
613666236637AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
23.6percentRootwinter; summerSerum, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
26.5percentRoot87Pearson0.05>= 0.05NoNo
616466236637AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
23.6percentRootwinter; summerSerum, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
26.5percentRoot87Pearson0.05>= 0.05NoYes
617866236651AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
23.6percentRootwinterSerum, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
2.42.2percentRoot87Pearson0.05>= 0.05No
619266236665AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Fatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
23.6percentRootsummerSerum, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
2.32.1percentRoot87Pearson0.03>= 0.05No
613766246638AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Linoleic acid (LA; cis-18:2n-6)23.5percentRootwinter; summerSerum, fastingGC-FIDLinoleic acid (LA; cis-18:2n-6)17.3percentRoot87Pearson-0.03>= 0.05NoNo
616566246638AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Linoleic acid (LA; cis-18:2n-6)23.5percentRootwinter; summerSerum, fastingGC-FIDLinoleic acid (LA; cis-18:2n-6)17.3percentRoot87Pearson-0.03>= 0.05NoYes
617966246652AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Linoleic acid (LA; cis-18:2n-6)23.5percentRootwinterSerum, fastingGC-FIDLinoleic acid (LA; cis-18:2n-6)17.717.8percentRoot87Pearson0.01>= 0.05No
619366246666AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Linoleic acid (LA; cis-18:2n-6)23.5percentRootsummerSerum, fastingGC-FIDLinoleic acid (LA; cis-18:2n-6)16.917.0percentRoot87Pearson-0.06>= 0.05No
613866256639AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Arachidonic acid (AA; cis-20:4n-6)0.4percentRootwinter; summerSerum, fastingGC-FIDArachidonic acid (AA; cis-20:4n-6)6.4percentRoot87Pearson-0.25< 0.05YesNo
616666256639AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Arachidonic acid (AA; cis-20:4n-6)0.4percentRootwinter; summerSerum, fastingGC-FIDArachidonic acid (AA; cis-20:4n-6)6.4percentRoot87Pearson-0.37< 0.001YesYes
618066256653AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Arachidonic acid (AA; cis-20:4n-6)0.4percentRootwinterSerum, fastingGC-FIDArachidonic acid (AA; cis-20:4n-6)6.46.3percentRoot87Pearson-0.24< 0.05Yes
619466256667AllMiddle-aged menJapanJPJPHC Study Cohort IDietary record (7-day)Arachidonic acid (AA; cis-20:4n-6)0.4percentRootsummerSerum, fastingGC-FIDArachidonic acid (AA; cis-20:4n-6)6.46.1percentRoot87Pearson-0.19>= 0.05No

Reproducibility values

IDMst. IDSubject groupPopulationCountryCountry codeCohortTime definitionBiological specimenExperimental methodBiomarkerBiomarker detailArithmetic meanGeometric meanMedianUnitAdjusted onReproducibility sizeICCICC 95% CI lowerICC 95% CI upperCV% WSCV% BSVAR WSVAR BS
3226626AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDFatty acids, saturated (SFA)Palmitic acid (16:0)
Stearic acid (18:0)
47.6percentRoot870.63
3236627AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDPalmitic acid (16:0)28.7percentRoot870.54
3246628AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDStearic acid (18:0)15.1percentRoot870.8
3256629AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDFatty acids, monounsaturated (MUFA)Oleic acid (cis-18:1n-9)
13.6percentRoot870.71
3266630AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDOleic acid (cis-18:1n-9)8.8percentRoot870.67
3276631AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDFatty acids, polyunsaturated (PUFA)Arachidonic acid (AA; cis-20:4n-6)
DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
Linoleic acid (LA; cis-18:2n-6)
alpha-Linolenic acid (ALA; cis-18:3n-3)
38.9percentRoot870.46
3286632AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDFatty acids, n3-polyunsaturated (n3-PUFA)DHA (cis-22:6n-3)
DPA (cis-22:5n-3)
EPA (cis-20:5n-3)
alpha-Linolenic acid (ALA; cis-18:3n-3)
12.4percentRoot870.76
3296633AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDalpha-Linolenic acid (ALA; cis-18:3n-3)0.2percentRoot870.61
3306634AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDEPA (cis-20:5n-3)3.7percentRoot870.68
3316635AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDDPA (cis-22:5n-3)1.2percentRoot870.83
3326636AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDDHA (cis-22:6n-3)7.3percentRoot870.77
3336637AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDFatty acids, n6-polyunsaturated (n6-PUFA)Arachidonic acid (AA; cis-20:4n-6)
Linoleic acid (LA; cis-18:2n-6)
26.5percentRoot870.72
3346638AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDLinoleic acid (LA; cis-18:2n-6)17.3percentRoot870.73
3356639AllMiddle-aged menJapanJPJPHC Study Cohort Iwinter; summerSerum, fastingGC-FIDArachidonic acid (AA; cis-20:4n-6)6.4percentRoot870.7