Kasper-Sonnenberg 2012

ID512
TitleLevels of phthalate metabolites in urine among mother-child-pairs - results from the Duisburg birth cohort study, Germany
AuthorsKasper-Sonnenberg, M.; Koch, H. M.; Wittsiepe, J.; Wilhelm, M.
Year2012
JournalInt J Hyg Environ Health
Volume215
Issue3
Pages373-382
PubMed ID21983396
DOI10.1016/j.ijheh.2011.09.004

Subjects

IDParent IDDepthSubject groupPopulationCountryCountry codeEthnicityCohortHealth conditionSmoker proportionSupplement users excluded?GenderFemale proportionSizeAge meanAge SDAge minAge maxAge medianHeight meanHeight SDHeight minHeight maxHeight medianWeight meanWeight SDWeight minWeight maxWeight medianBMI meanBMI SDBMI minBMI maxBMI median
16790AllMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyHealthyUnspecifiedFemale + Male207
168016791ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyHealthyUnspecifiedFemale + Male45.01046.80.616.01.8
168116791MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyHealthyUnspecifiedFemale100.010339.24.625.45.8

Biomarker concentration values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed as
194960ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMonomethyl phthalate (MMP)10498.04.83.76.2ug/g4.8 ug/gDensityCreatinine
194970ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)10438.130.947.1ug/g38.1 ug/gDensityCreatinine
194980ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMonobenzyl phthalate (MBzP)104100.012.210.214.6ug/g12.2 ug/gDensityCreatinine
19499195011ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-n-butyl phthalate (MnBP)104100.046.940.853.9ug/g46.9 ug/gDensityCreatinine
19500195011ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-hydroxy-n-butyl phthalate (OH-MnBP)10496.06.85.68.3ug/g6.8 ug/gDensityCreatinine
195010ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisDnBP metabolitesMono-hydroxy-n-butyl phthalate (OH-MnBP)
Mono-n-butyl phthalate (MnBP)
10455.448.263.8ug/g55.4 ug/gDensityCreatinine
19502195051ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono(3-carboxypropyl) phthalate (MCPP)10497.02.52.22.9ug/g2.5 ug/gDensityCreatinine
19503195051ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-isobutyl phthalate (MiBP)104100.064.655.275.7ug/g64.6 ug/gDensityCreatinine
19504195051ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-hydroxy-iso-butyl phthalate (OH-MiBP)10499.034.228.541.0ug/g34.2 ug/gDensityCreatinine
195050ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisDiBP metabolitesMono(3-carboxypropyl) phthalate (MCPP)
Mono-hydroxy-iso-butyl phthalate (OH-MiBP)
Mono-isobutyl phthalate (MiBP)
104101.087.2118.0ug/g101.0 ug/gDensityCreatinine
19508195131ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono(2-ethylhexyl) phthalate (MEHP)104100.03.83.34.4ug/g3.8 ug/gDensityCreatinine
19509195131ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP)104100.028.625.232.4ug/g28.6 ug/gDensityCreatinine
19510195131ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono(2-ethyl-5-oxohexyl) phthalate (MEOHP)104100.025.622.828.8ug/g25.6 ug/gDensityCreatinine
19511195131ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono(2-ethyl-5-carboxypentyl) phthalate (MECPP)104100.040.836.445.7ug/g40.8 ug/gDensityCreatinine
195130ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisDEHP metabolitesMono(2-ethyl-5-carboxypentyl) phthalate (MECPP)
Mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP)
Mono(2-ethyl-5-oxohexyl) phthalate (MEOHP)
Mono(2-ethylhexyl) phthalate (MEHP)
104100.054.348.161.3ug/g54.3 ug/gDensityCreatinine
19514195171ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-hydroxy-isononyl phthalate (OH-MiNP)104100.015.113.516.8ug/g15.1 ug/gDensityCreatinine
19515195171ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)104100.05.74.96.6ug/g5.7 ug/gDensityCreatinine
19516195171ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-carboxy-isononyl phthalate (cx-MiNP)104100.010.08.911.2ug/g10.0 ug/gDensityCreatinine
195170ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisDiNP metabolitesMono-carboxy-isononyl phthalate (cx-MiNP)
Mono-hydroxy-isononyl phthalate (OH-MiNP)
Mono-oxo-isononyl phthalate (oxo-MiNP)
10431.928.535.8ug/g31.9 ug/gDensityCreatinine
19518195211ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-hydroxy-isodecyl phthalate (OH-MiDP)10497.02.11.72.5ug/g2.1 ug/gDensityCreatinine
19519195211ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isodecyl phthalate (oxo-MiDP)10495.00.60.50.7ug/g0.6 ug/gDensityCreatinine
19520195211ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-carboxy-isodecyl phthalate (cx-MiDP)104100.01.31.11.5ug/g1.3 ug/gDensityCreatinine
195210ChildrenMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisDiDP metabolitesMono-carboxy-isodecyl phthalate (cx-MiDP)
Mono-hydroxy-isodecyl phthalate (OH-MiDP)
Mono-oxo-isodecyl phthalate (oxo-MiDP)
1044.23.64.9ug/g4.2 ug/gDensityCreatinine
195230MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMonomethyl phthalate (MMP)10366.01.10.81.5ug/g1.1 ug/gDensityCreatinine
195240MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMonoethyl phthalate (MEP)103100.042.334.152.5ug/g42.3 ug/gDensityCreatinine
195250MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMonobenzyl phthalate (MBzP)103100.05.54.86.4ug/g5.5 ug/gDensityCreatinine
19526195281MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-n-butyl phthalate (MnBP)103100.027.524.830.5ug/g27.5 ug/gDensityCreatinine
19527195281MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-hydroxy-n-butyl phthalate (OH-MnBP)10375.01.71.22.3ug/g1.7 ug/gDensityCreatinine
195280MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisDnBP metabolitesMono-hydroxy-n-butyl phthalate (OH-MnBP)
Mono-n-butyl phthalate (MnBP)
10330.427.333.8ug/g30.4 ug/gDensityCreatinine
19529195321MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono(3-carboxypropyl) phthalate (MCPP)10355.00.550.40.6ug/g0.6 ug/gDensityCreatinine
19530195321MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-isobutyl phthalate (MiBP)103100.037.231.843.5ug/g37.2 ug/gDensityCreatinine
19531195321MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-hydroxy-iso-butyl phthalate (OH-MiBP)103100.017.415.120.0ug/g17.4 ug/gDensityCreatinine
195320MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisDiBP metabolitesMono(3-carboxypropyl) phthalate (MCPP)
Mono-hydroxy-iso-butyl phthalate (OH-MiBP)
Mono-isobutyl phthalate (MiBP)
10355.948.464.5ug/g55.9 ug/gDensityCreatinine
19535195391MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono(2-ethylhexyl) phthalate (MEHP)103100.03.73.14.5ug/g3.7 ug/gDensityCreatinine
19536195391MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP)103100.014.112.216.2ug/g14.1 ug/gDensityCreatinine
19537195391MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono(2-ethyl-5-oxohexyl) phthalate (MEOHP)103100.010.08.711.5ug/g10.0 ug/gDensityCreatinine
19538195391MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono(2-ethyl-5-carboxypentyl) phthalate (MECPP)103100.017.715.520.3ug/g17.7 ug/gDensityCreatinine
195390MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisDEHP metabolitesMono(2-ethyl-5-carboxypentyl) phthalate (MECPP)
Mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP)
Mono(2-ethyl-5-oxohexyl) phthalate (MEOHP)
Mono(2-ethylhexyl) phthalate (MEHP)
10324.221.027.8ug/g24.2 ug/gDensityCreatinine
19540195431MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-hydroxy-isononyl phthalate (OH-MiNP)103100.09.68.311.2ug/g9.6 ug/gDensityCreatinine
19541195431MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)103100.03.02.53.5ug/g3.0 ug/gDensityCreatinine
19542195431MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-carboxy-isononyl phthalate (cx-MiNP)103100.04.74.05.4ug/g4.7 ug/gDensityCreatinine
195430MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisDiNP metabolitesMono-carboxy-isononyl phthalate (cx-MiNP)
Mono-hydroxy-isononyl phthalate (OH-MiNP)
Mono-oxo-isononyl phthalate (oxo-MiNP)
10318.315.821.3ug/g18.3 ug/gDensityCreatinine
19544195471MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-hydroxy-isodecyl phthalate (OH-MiDP)10398.01.51.21.8ug/g1.5 ug/gDensityCreatinine
19545195471MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isodecyl phthalate (oxo-MiDP)10389.00.40.30.4ug/g0.4 ug/gDensityCreatinine
19546195471MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisMono-carboxy-isodecyl phthalate (cx-MiDP)10395.00.50.50.6ug/g0.5 ug/gDensityCreatinine
195470MothersMother-child pairs in the industrialized city of DuisburgGermanyDEThe Duisburg birth cohort studyUrine, first morning spotLC-MS/MS after enzymatic hydrolysisDiDP metabolitesMono-carboxy-isodecyl phthalate (cx-MiDP)
Mono-hydroxy-isodecyl phthalate (OH-MiDP)
Mono-oxo-isodecyl phthalate (oxo-MiDP)
1032.62.23.0ug/g2.6 ug/gDensityCreatinine

Intake values

No data available

Correlation values

No data available

Reproducibility values

No data available