Lin 2011

ID533
TitlePhthalate exposure in pregnant women and their children in central Taiwan
AuthorsLin, S.; Ku, H. Y.; Su, P. H.; Chen, J. W.; Huang, P. C.; Angerer, J.; Wang, S. L.
Year2011
JournalChemosphere
Volume82
Issue7
Pages947-955
PubMed ID21075419
DOI10.1016/j.chemosphere.2010.10.073

Subjects

IDParent IDDepthSubject groupPopulationCountryCountry codeEthnicityCohortHealth conditionSmoker proportionSupplement users excluded?GenderFemale proportionSizeAge meanAge SDAge minAge maxAge medianHeight meanHeight SDHeight minHeight maxHeight medianWeight meanWeight SDWeight minWeight maxWeight medianBMI meanBMI SDBMI minBMI maxBMI median
17300MothersPregnant women and their childrenTaiwanTWPregnantUnspecifiedFemale100.010029.233.8221.039.0
173117301Mothers providing milk samplesPregnant women and their childrenTaiwanTWUnspecifiedFemale100.02928.24.23
17320NewbornsPregnant women and their childrenTaiwanTWUnspecifiedFemale + Male50.030
17330Children aged 2-3 yearsPregnant women and their childrenTaiwanTWUnspecifiedFemale + Male50.030
17340Children aged 5-6 yearsPregnant women and their childrenTaiwanTWUnspecifiedFemale + Male54.059

Biomarker concentration values

IDParent IDDepthSubject groupPopulationCountryCountry codeCohortTime definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianAdjustment typeAdjusted onRegressed onExpressed as
200130MothersPregnant women and their childrenTaiwanTWpregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMono(2-ethylhexyl) phthalate (MEHP)10017.340.3816.37353.914.0721.36ug/g17.3 ug/g16.4 ug/gDensityCreatinine
200140MothersPregnant women and their childrenTaiwanTWpregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP)10036.37.4933.22114.030.1843.67ug/g36.3 ug/g33.2 ug/gDensityCreatinine
200150MothersPregnant women and their childrenTaiwanTWpregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMono(2-ethyl-5-oxohexyl) phthalate (MEOHP)10036.978.0629.52663.030.9144.22ug/g37.0 ug/g29.5 ug/gDensityCreatinine
200160MothersPregnant women and their childrenTaiwanTWpregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMono(2-ethyl-5-carboxypentyl) phthalate (MECPP)10052.435.6944.693545.043.6262.83ug/g52.4 ug/g44.7 ug/gDensityCreatinine
200170MothersPregnant women and their childrenTaiwanTWpregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMono(2-carboxymethylhexyl) phthalate (MCMHP)10012.171.510.19756.09.9714.86ug/g12.2 ug/g10.2 ug/gDensityCreatinine
200180MothersPregnant women and their childrenTaiwanTWpregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMono-isobutyl phthalate (MiBP)10018.42.4515.19165.014.7522.05ug/g18.4 ug/g15.2 ug/gDensityCreatinine
200190MothersPregnant women and their childrenTaiwanTWpregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMono-n-butyl phthalate (MnBP)100102.326.887.49569.087.12120.12ug/g102.3 ug/g87.5 ug/gDensityCreatinine
200200MothersPregnant women and their childrenTaiwanTWpregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMonobenzyl phthalate (MBzP)1004.340.082.07235.03.275.76ug/g4.3 ug/g2.1 ug/gDensityCreatinine
200210MothersPregnant women and their childrenTaiwanTWpregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMono-hydroxy-isononyl phthalate (OH-MiNP)1000.910.080.42267.50.061.38ug/g0.9 ug/g0.4 ug/gDensityCreatinine
200220MothersPregnant women and their childrenTaiwanTWpregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)1000.650.080.34262.00.440.98ug/g0.7 ug/g0.3 ug/gDensityCreatinine
200230MothersPregnant women and their childrenTaiwanTWpregnancyUrine, spotLC-MS/MS after enzymatic hydrolysisMono-carboxy-isononyl phthalate (cx-MiNP)1000.920.080.41283.00.61.4ug/g0.9 ug/g0.4 ug/gDensityCreatinine
200450Mothers providing milk samplesPregnant women and their childrenTaiwanTWBreast milkLC-MS/MS after enzymatic hydrolysisMono(2-ethylhexyl) phthalate (MEHP)292.493.61.254.98mg/L2.5 mg/L3.6 mg/LCrude
200470Mothers providing milk samplesPregnant women and their childrenTaiwanTWBreast milkLC-MS/MS after enzymatic hydrolysisMono(2-ethyl-5-oxohexyl) phthalate (MEOHP)290.260.240.26mg/L0.3 mg/LCrude
200480Mothers providing milk samplesPregnant women and their childrenTaiwanTWBreast milkLC-MS/MS after enzymatic hydrolysisMono(2-ethyl-5-carboxypentyl) phthalate (MECPP)290.280.230.35mg/L0.3 mg/LCrude
200500Mothers providing milk samplesPregnant women and their childrenTaiwanTWBreast milkLC-MS/MS after enzymatic hydrolysisMono-isobutyl phthalate (MiBP)291.10.50.681.78mg/L1.1 mg/L0.5 mg/LCrude
200510Mothers providing milk samplesPregnant women and their childrenTaiwanTWBreast milkLC-MS/MS after enzymatic hydrolysisMono-n-butyl phthalate (MnBP)292.884.051.714.83mg/L2.9 mg/L4.1 mg/LCrude
200520Mothers providing milk samplesPregnant women and their childrenTaiwanTWBreast milkLC-MS/MS after enzymatic hydrolysisMonobenzyl phthalate (MBzP)291.10.681.78mg/L1.1 mg/LCrude
200780NewbornsPregnant women and their childrenTaiwanTWCord serumLC-MS/MS after enzymatic hydrolysisMono(2-ethylhexyl) phthalate (MEHP)302.493.021.254.98ug/L0.0 mg/L0.0 mg/LCrude
200810NewbornsPregnant women and their childrenTaiwanTWCord serumLC-MS/MS after enzymatic hydrolysisMono(2-ethyl-5-carboxypentyl) phthalate (MECPP)300.281.280.230.35ug/L0.0 mg/L0.0 mg/LCrude
200820NewbornsPregnant women and their childrenTaiwanTWCord serumLC-MS/MS after enzymatic hydrolysisMono(2-carboxymethylhexyl) phthalate (MCMHP)301.56ug/L0.0 mg/LCrude
200830NewbornsPregnant women and their childrenTaiwanTWCord serumLC-MS/MS after enzymatic hydrolysisMono-isobutyl phthalate (MiBP)301.13.440.681.78ug/L0.0 mg/L0.0 mg/LCrude
200840NewbornsPregnant women and their childrenTaiwanTWCord serumLC-MS/MS after enzymatic hydrolysisMono-n-butyl phthalate (MnBP)302.8823.91.714.83ug/L0.0 mg/L0.0 mg/LCrude
200850NewbornsPregnant women and their childrenTaiwanTWCord serumLC-MS/MS after enzymatic hydrolysisMonobenzyl phthalate (MBzP)300.720.250.3ug/L0.0 mg/LCrude
200670Children aged 2-3 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono(2-ethylhexyl) phthalate (MEHP)3027.521.0418.540.9ug/g27.5 ug/g21.0 ug/gDensityCreatinine
200680Children aged 2-3 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP)30140.4150.8594.4208.9ug/g140.4 ug/g150.9 ug/gDensityCreatinine
200690Children aged 2-3 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono(2-ethyl-5-oxohexyl) phthalate (MEOHP)30116.3114.3378.9171.6ug/g116.3 ug/g114.3 ug/gDensityCreatinine
200700Children aged 2-3 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono(2-ethyl-5-carboxypentyl) phthalate (MECPP)30241.0206.62164.0353.0ug/g241.0 ug/g206.6 ug/gDensityCreatinine
200710Children aged 2-3 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono(2-carboxymethylhexyl) phthalate (MCMHP)3054.554.0436.681.3ug/g54.5 ug/g54.0 ug/gDensityCreatinine
200720Children aged 2-3 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono-isobutyl phthalate (MiBP)3055.150.9740.075.9ug/g55.1 ug/g51.0 ug/gDensityCreatinine
200730Children aged 2-3 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono-n-butyl phthalate (MnBP)30332.0314.0257.0428.0ug/g332.0 ug/g314.0 ug/gDensityCreatinine
200740Children aged 2-3 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMonobenzyl phthalate (MBzP)3010.911.256.718.0ug/g10.9 ug/g11.3 ug/gDensityCreatinine
200750Children aged 2-3 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono-hydroxy-isononyl phthalate (OH-MiNP)306.7820.023.6612.58ug/g6.8 ug/g20.0 ug/gDensityCreatinine
200760Children aged 2-3 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)302.869.221.316.2ug/g2.9 ug/g9.2 ug/gDensityCreatinine
200770Children aged 2-3 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono-carboxy-isononyl phthalate (cx-MiNP)3027.821.1815.948.5ug/g27.8 ug/g21.2 ug/gDensityCreatinine
200560Children aged 5-6 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono(2-ethylhexyl) phthalate (MEHP)5922.7321.3718.228.4mg/L22.7 mg/L21.4 mg/LDensityCreatinine
200570Children aged 5-6 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP)5982.269.0565.6103.0mg/L82.2 mg/L69.1 mg/LDensityCreatinine
200580Children aged 5-6 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono(2-ethyl-5-oxohexyl) phthalate (MEOHP)5963.958.7151.179.9mg/L63.9 mg/L58.7 mg/LDensityCreatinine
200590Children aged 5-6 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono(2-ethyl-5-carboxypentyl) phthalate (MECPP)59137.9131.86110.7171.7ug/g137.9 ug/g131.9 ug/gDensityCreatinine
200600Children aged 5-6 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono(2-carboxymethylhexyl) phthalate (MCMHP)5929.427.1623.337.0ug/g29.4 ug/g27.2 ug/gDensityCreatinine
200610Children aged 5-6 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono-isobutyl phthalate (MiBP)5957.054.1347.568.4ug/g57.0 ug/g54.1 ug/gDensityCreatinine
200620Children aged 5-6 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono-n-butyl phthalate (MnBP)59169.5154.53135.0212.9ug/g169.5 ug/g154.5 ug/gDensityCreatinine
200630Children aged 5-6 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMonobenzyl phthalate (MBzP)598.157.646.3910.39ug/g8.2 ug/g7.6 ug/gDensityCreatinine
200640Children aged 5-6 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono-hydroxy-isononyl phthalate (OH-MiNP)5921.817.7216.129.6ug/g21.8 ug/g17.7 ug/gDensityCreatinine
200650Children aged 5-6 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono-oxo-isononyl phthalate (oxo-MiNP)5911.649.588.6115.6ug/g11.6 ug/g9.6 ug/gDensityCreatinine
200660Children aged 5-6 yearsPregnant women and their childrenTaiwanTWUrine, spotLC-MS/MS after enzymatic hydrolysisMono-carboxy-isononyl phthalate (cx-MiNP)5927.6122.3620.0936.5ug/g27.6 ug/g22.4 ug/gDensityCreatinine

Intake values

No data available

Correlation values

No data available

Reproducibility values

No data available