Ye 2008
| ID | 547 |
|---|---|
| Title | Urinary metabolite concentrations of organophosphorous pesticides, bisphenol A, and phthalates among pregnant women in Rotterdam, the Netherlands: The Generation R study |
| Authors | Ye, X.; Pierik, F. H.; Hauser, R.; Duty, S.; Angerer, J.; Park, M. M.; Burdorf, A.; Hofman, A.; Jaddoe, V. W.; Mackenbach, J. P.; Steegers, E. A.; Tiemeier, H.; Longnecker, M. P. |
| Year | 2008 |
| Journal | Environ Res |
| Volume | 108 |
| Issue | 2 |
| Pages | 260-267 |
| PubMed ID | 18774129 |
| DOI | 10.1016/j.envres.2008.07.014 |
Subjects
| ID | Parent ID | Depth | Subject group | Population | Country | Country code | Ethnicity | Cohort | Health condition | Smoker proportion | Supplement users excluded? | Gender | Female proportion | Size | Age mean | Age SD | Age min | Age max | Age median | Height mean | Height SD | Height min | Height max | Height median | Weight mean | Weight SD | Weight min | Weight max | Weight median | BMI mean | BMI SD | BMI min | BMI max | BMI median |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1767 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | Pregnant | Unspecified | Female | 100.0 | 100 | 18.0 | 41.0 | 30.0 |
Biomarker concentration values
| ID | Parent ID | Depth | Subject group | Population | Country | Country code | Cohort | Time definition | Biospecimen | Analytical method | Biomarker | Biomarker detail | Measurement size | Detected (nb) | Detected (%) | Detected only? | Arithmethic mean | Arithmethic SD | Geometric mean | Geometric SD | Min | Min (detected) | Percentile_05 | Percentile_10 | Percentile_25 | Median | Percentile_75 | Percentile_90 | Percentile_95 | Max | Interquartile range | Mean 95% CI lower | Mean 95% CI upper | GMean 95% CI lower | GMean 95% CI upper | Unit | Converted arithmetic mean | Converted geometric mean | Converted median | Adjustment type | Adjusted on | Regressed on | Expressed as |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 20332 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Monoethyl phthalate (MEP) | 100 | 97.0 | 112.0 | 5.6 | 37.9 | 117.0 | 425.0 | 4330.0 | ug/L | 0.1 mg/L | 0.1 mg/L | Crude | |||||||||||||||||||||
| 20334 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Mono(3-carboxypropyl) phthalate (MCPP) | 100 | 94.0 | 0.8 | 2.8 | 0.5 | 1.0 | 1.6 | 8.2 | ug/L | 0.0 mg/L | 0.0 mg/L | Crude | |||||||||||||||||||||
| 20335 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Mono-n-butyl phthalate (MnBP) | 100 | 100.0 | 43.2 | 3.1 | 4.7 | 21.2 | 42.7 | 86.6 | 420.8 | ug/L | 0.0 mg/L | 0.0 mg/L | Crude | ||||||||||||||||||||
| 20336 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Mono-isobutyl phthalate (MiBP) | 100 | 100.0 | 41.3 | 3.0 | 5.3 | 21.7 | 42.1 | 72.8 | 759.0 | ug/L | 0.0 mg/L | 0.0 mg/L | Crude | ||||||||||||||||||||
| 20337 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Monobenzyl phthalate (MBzP) | 100 | 100.0 | 8.9 | 2.8 | 1.3 | 3.6 | 7.5 | 16.8 | 320.0 | ug/L | 0.0 mg/L | 0.0 mg/L | Crude | ||||||||||||||||||||
| 20338 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Mono(2-ethylhexyl) phthalate (MEHP) | 100 | 96.0 | 6.9 | 2.7 | 3.3 | 6.9 | 17.3 | 392.0 | ug/L | 0.0 mg/L | 0.0 mg/L | Crude | |||||||||||||||||||||
| 20339 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) | 100 | 100.0 | 14.3 | 4.7 | 0.5 | 6.9 | 14.0 | 30.0 | 494.0 | ug/L | 0.0 mg/L | 0.0 mg/L | Crude | ||||||||||||||||||||
| 20340 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Mono(2-ethyl-5-oxohexyl) phthalate (MEOHP) | 100 | 100.0 | 15.0 | 2.6 | 0.7 | 7.2 | 14.5 | 27.4 | 514.0 | ug/L | 0.0 mg/L | 0.0 mg/L | Crude | ||||||||||||||||||||
| 20341 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Mono(2-ethyl-5-carboxypentyl) phthalate (MECPP) | 100 | 100.0 | 19.4 | 2.8 | 1.2 | 9.6 | 18.4 | 31.5 | 421.0 | ug/L | 0.0 mg/L | 0.0 mg/L | Crude | ||||||||||||||||||||
| 20342 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Mono(2-carboxymethylhexyl) phthalate (MCMHP) | 100 | 100.0 | 6.2 | 3.2 | 0.5 | 2.9 | 6.2 | 11.1 | 67.3 | ug/L | 0.0 mg/L | 0.0 mg/L | Crude | ||||||||||||||||||||
| 20343 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Mono-oxo-isononyl phthalate (oxo-MiNP) | 100 | 96.0 | 2.5 | 3.7 | 1.2 | 2.2 | 5.1 | 152.0 | ug/L | 0.0 mg/L | 0.0 mg/L | Crude | |||||||||||||||||||||
| 20344 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Mono-hydroxy-isononyl phthalate (OH-MiNP) | 100 | 98.0 | 3.0 | 3.6 | 1.4 | 2.5 | 6.5 | 122.0 | ug/L | 0.0 mg/L | 0.0 mg/L | Crude | |||||||||||||||||||||
| 20345 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | GC-MS/MS after enzymatic hydrolysis | Bisphenol A (BPA) | 100 | 82.0 | 1.1 | 3.8 | 0.5 | 1.2 | 2.5 | 46.0 | ug/L | 0.0 mg/L | 0.0 mg/L | Crude | |||||||||||||||||||||
| 20348 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Monoethyl phthalate (MEP) | 100 | 173.0 | 4.7 | 71.9 | 222.0 | 487.0 | 7160.0 | ug/g | 173.0 ug/g | 222.0 ug/g | Density | Creatinine | |||||||||||||||||||||
| 20350 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Mono(3-carboxypropyl) phthalate (MCPP) | 100 | 1.3 | 2.3 | 0.9 | 1.4 | 2.5 | 8.9 | ug/g | 1.3 ug/g | 1.4 ug/g | Density | Creatinine | |||||||||||||||||||||
| 20351 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Mono-n-butyl phthalate (MnBP) | 100 | 67.1 | 2.2 | 15.3 | 41.6 | 62.2 | 106.0 | 351.0 | ug/g | 67.1 ug/g | 62.2 ug/g | Density | Creatinine | ||||||||||||||||||||
| 20352 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Mono-isobutyl phthalate (MiBP) | 100 | 64.1 | 2.1 | 14.4 | 35.1 | 57.1 | 99.4 | 640.0 | ug/g | 64.1 ug/g | 57.1 ug/g | Density | Creatinine | ||||||||||||||||||||
| 20353 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Monobenzyl phthalate (MBzP) | 100 | 13.9 | 2.0 | 3.0 | 7.6 | 11.7 | 22.6 | 405.0 | ug/g | 13.9 ug/g | 11.7 ug/g | Density | Creatinine | ||||||||||||||||||||
| 20354 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Mono(2-ethylhexyl) phthalate (MEHP) | 100 | 10.8 | 2.1 | 6.9 | 9.9 | 20.9 | 321.0 | ug/g | 10.8 ug/g | 9.9 ug/g | Density | Creatinine | |||||||||||||||||||||
| 20355 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) | 100 | 22.2 | 3.4 | 3.7 | 13.2 | 20.3 | 32.3 | 371.0 | ug/g | 22.2 ug/g | 20.3 ug/g | Density | Creatinine | ||||||||||||||||||||
| 20356 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Mono(2-ethyl-5-oxohexyl) phthalate (MEOHP) | 100 | 23.3 | 2.0 | 5.3 | 15.6 | 20.9 | 30.7 | 386.0 | ug/g | 23.3 ug/g | 20.9 ug/g | Density | Creatinine | ||||||||||||||||||||
| 20357 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Mono(2-ethyl-5-carboxypentyl) phthalate (MECPP) | 100 | 30.1 | 2.3 | 8.1 | 18.9 | 25.8 | 41.4 | 317.0 | ug/g | 30.1 ug/g | 25.8 ug/g | Density | Creatinine | ||||||||||||||||||||
| 20358 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Mono(2-carboxymethylhexyl) phthalate (MCMHP) | 100 | 9.7 | 2.6 | 1.6 | 5.5 | 9.1 | 16.1 | 73.6 | ug/g | 9.7 ug/g | 9.1 ug/g | Density | Creatinine | ||||||||||||||||||||
| 20359 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Mono-oxo-isononyl phthalate (oxo-MiNP) | 100 | 3.9 | 3.2 | 1.9 | 3.4 | 5.9 | 119.0 | ug/g | 3.9 ug/g | 3.4 ug/g | Density | Creatinine | |||||||||||||||||||||
| 20360 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | LC-MS/MS after enzymatic hydrolysis | Mono-hydroxy-isononyl phthalate (OH-MiNP) | 100 | 4.6 | 2.9 | 2.3 | 4.2 | 7.0 | 95.7 | ug/g | 4.6 ug/g | 4.2 ug/g | Density | Creatinine | |||||||||||||||||||||
| 20361 | 0 | All | Pregnant women from Rotterdam | Netherlands | NL | Generation R study | pregnancy | Urine, spot | GC-MS/MS after enzymatic hydrolysis | Bisphenol A (BPA) | 100 | 1.7 | 2.8 | 0.1 | 0.3 | 0.8 | 1.6 | 3.9 | 8.3 | 22.7 | ug/g | 1.7 ug/g | 1.6 ug/g | Density | Creatinine |
Intake values
No data available
Correlation values
No data available
Reproducibility values
No data available