Exposome-Explorer: show publications

Bowman 2011

ID	63
Title	Reliability and validity of food frequency questionnaire and nutrient biomarkers in elders with and without mild cognitive impairment
Authors	Bowman, G. L.; Shannon, J.; Ho, E.; Traber, M. G.; Frei, B.; Oken, B. S.; Kaye, J. A.; Quinn, J. F.
Year	2011
Journal	Alzheimer Dis Assoc Disord
Volume	25
Issue	1
Pages	49-57
PubMed ID	20856100
DOI	10.1097/WAD.0b013e3181f333d6

Subjects

ID	Parent ID	Depth	Subject group	Population	Country	Country code	Ethnicity	Health condition	Supplement users excluded?	Gender	Female proportion	Size	Age mean	Age SD	Age min	Age max	BMI mean	BMI SD
234		0	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	White (100%)		No	Female + Male	50.0	38			60.0	100.0
232	234	1	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	White (100%)	Amnesic Mild Cognitive Impairment	No	Female + Male	32.0	19	73.0	9.0			27.0	3.0
233	234	1	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	White (100%)	Healthy	No	Female + Male	68.0	19	75.0	6.0			26.0	5.0

Biomarker concentration values

No data available

Intake values

ID	Parent ID	Depth	Subject group	Population	Country	Country code	Cohort	Time definition	Intake tool	Intake food coverage	Intake time coverage	Intake assessment	Compound	Compound detail	Supplement intakes included?	Measurement size	Detected (nb)	Detected (%)	Detected only?	Arithmethic mean	Arithmethic SD	Geometric mean	Geometric SD	Min	Min (detected)	Percentile_05	Percentile_10	Percentile_25	Median	Percentile_75	Percentile_90	Percentile_95	Max	Interquartile range	Mean 95% CI lower	Mean 95% CI upper	GMean 95% CI lower	GMean 95% CI upper	Unit	Converted arithmetic mean	Converted geometric mean	Converted median	Adjustment type	Adjusted on	Regressed on	Expressed as
3319		0	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US		baseline	NCI DHQ + Diet Calc	124-item		Food Frequency Questionnaire (FFQ)	Energy			19				1549.0	566.0																		kcal/day	1549.0 kcal/day			Crude
3320		0	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US		baseline	NCI DHQ + Diet Calc	124-item		Food Frequency Questionnaire (FFQ)	Energy			19				1679.0	505.0																		kcal/day	1679.0 kcal/day			Crude

Correlation values

ID	Intake ID	Excretion ID	Subject group	Population	Country	Country code	Intake Time definition	Intake assessment	Intake	Intake detail	Intake Unit	Biomarker Time definition	Biological specimen	Biomarker Experimental method	Biomarker	Biomarker detail	Biomarker Unit	Correlation size	Correlation type	Correlation value	Correlation p-value	Significant?	Measurement adjustment	Covariates
1520	1645	1712	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin C		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Ascorbic acid		missing unit	19	Pearson	0.15	>= 0.05	No
1586	1645	1712	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin C		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Ascorbic acid		missing unit	19	Pearson	0.15	>= 0.05	No	Energy by residual method
1652	1645	1712	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin C		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Ascorbic acid		missing unit	19	Pearson	0.09	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1521	1646	1713	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Tocopherol		missing unit	baseline; 1 month	Plasma, fasting	HPLC	alpha-Tocopherol		missing unit	19	Pearson	0.15	>= 0.05	No
1587	1646	1713	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Tocopherol		missing unit	baseline; 1 month	Plasma, fasting	HPLC	alpha-Tocopherol		missing unit	19	Pearson	0.15	>= 0.05	No	Energy by residual method
1653	1646	1713	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Tocopherol		missing unit	baseline; 1 month	Plasma, fasting	HPLC	alpha-Tocopherol		missing unit	19	Pearson	0.21	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1522	1647	1714	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	gamma-Tocopherol		missing unit	baseline; 1 month	Plasma, fasting	HPLC	gamma-Tocopherol		missing unit	19	Pearson	-0.2	>= 0.05	No
1588	1647	1714	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	gamma-Tocopherol		missing unit	baseline; 1 month	Plasma, fasting	HPLC	gamma-Tocopherol		missing unit	19	Pearson	-0.2	>= 0.05	No	Energy by residual method
1654	1647	1714	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	gamma-Tocopherol		missing unit	baseline; 1 month	Plasma, fasting	HPLC	gamma-Tocopherol		missing unit	19	Pearson	-0.37	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1523	1648	1715	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Lutein/Zeaxanthin		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Lutein/Zeaxanthin		missing unit	19	Pearson	-0.19	>= 0.05	No
1589	1648	1715	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Lutein/Zeaxanthin		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Lutein/Zeaxanthin		missing unit	19	Pearson	-0.19	>= 0.05	No	Energy by residual method
1655	1648	1715	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Lutein/Zeaxanthin		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Lutein/Zeaxanthin		missing unit	19	Pearson	-0.35	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1524	1649	1716	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	beta-Cryptoxanthin		missing unit	baseline; 1 month	Plasma, fasting	HPLC	beta-Cryptoxanthin		missing unit	19	Pearson	-0.11	>= 0.05	No
1590	1649	1716	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	beta-Cryptoxanthin		missing unit	baseline; 1 month	Plasma, fasting	HPLC	beta-Cryptoxanthin		missing unit	19	Pearson	-0.11	>= 0.05	No	Energy by residual method
1656	1649	1716	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	beta-Cryptoxanthin		missing unit	baseline; 1 month	Plasma, fasting	HPLC	beta-Cryptoxanthin		missing unit	19	Pearson	-0.15	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1525	1650	1717	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Carotene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	alpha-Carotene		missing unit	19	Pearson	0.43	>= 0.05	No
1591	1650	1717	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Carotene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	alpha-Carotene		missing unit	19	Pearson	0.43	>= 0.05	No	Energy by residual method
1657	1650	1717	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Carotene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	alpha-Carotene		missing unit	19	Pearson	0.44	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1526	1651	1718	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	beta-Carotene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	beta-Carotene		missing unit	19	Pearson	0.45	>= 0.05	No
1592	1651	1718	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	beta-Carotene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	beta-Carotene		missing unit	19	Pearson	0.35	>= 0.05	No	Energy by residual method
1658	1651	1718	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	beta-Carotene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	beta-Carotene		missing unit	19	Pearson	0.22	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1527	1652	1719	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Lycopene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Lycopene		missing unit	19	Pearson	-0.01	>= 0.05	No
1593	1652	1719	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Lycopene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Lycopene		missing unit	19	Pearson	0.01	>= 0.05	No	Energy by residual method
1659	1652	1719	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Lycopene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Lycopene		missing unit	19	Pearson	0.06	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1528	1653	1720	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin B6		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Pyridoxal 5'-phosphate		missing unit	19	Pearson	0.05	>= 0.05	No
1594	1653	1720	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin B6		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Pyridoxal 5'-phosphate		missing unit	19	Pearson	0.09	>= 0.05	No	Energy by residual method
1660	1653	1720	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin B6		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Pyridoxal 5'-phosphate		missing unit	19	Pearson	0.12	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1529	1654	1721	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Folates		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Folates		missing unit	19	Pearson	-0.25	>= 0.05	No
1595	1654	1721	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Folates		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Folates		missing unit	19	Pearson	0.04	>= 0.05	No	Energy by residual method
1661	1654	1721	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Folates		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Folates		missing unit	19	Pearson	0.04	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1530	1655	1722	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin B12		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Vitamin B12		missing unit	19	Pearson	0.1	>= 0.05	No
1596	1655	1722	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin B12		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Vitamin B12		missing unit	19	Pearson	-0.25	>= 0.05	No	Energy by residual method
1662	1655	1722	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin B12		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Vitamin B12		missing unit	19	Pearson	-0.07	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1531	1656	1723	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin D		missing unit	baseline; 1 month	Plasma, fasting	HPLC	25-Hydroxycholecalciferol		missing unit	19	Pearson	0.15	>= 0.05	No
1597	1656	1723	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin D		missing unit	baseline; 1 month	Plasma, fasting	HPLC	25-Hydroxycholecalciferol		missing unit	19	Pearson	0.1	>= 0.05	No	Energy by residual method
1663	1656	1723	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin D		missing unit	baseline; 1 month	Plasma, fasting	HPLC	25-Hydroxycholecalciferol		missing unit	19	Pearson	0.18	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1533	1657	1724	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, polyunsaturated (PUFA)	Arachidonic acid (AA; cis-20:4n-6) DHA (cis-22:6n-3) EPA (cis-20:5n-3) Linoleic acid (LA; cis-18:2n-6) alpha-Linolenic acid (ALA; cis-18:3n-3)	missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, polyunsaturated (PUFA)	Arachidonic acid (AA; cis-20:4n-6) DHA (cis-22:6n-3) EPA (cis-20:5n-3) Linoleic acid (LA; cis-18:2n-6) alpha-Linolenic acid (ALA; cis-18:3n-3)	missing unit	19	Pearson	-0.06	>= 0.05	No
1599	1657	1724	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, polyunsaturated (PUFA)	Arachidonic acid (AA; cis-20:4n-6) DHA (cis-22:6n-3) EPA (cis-20:5n-3) Linoleic acid (LA; cis-18:2n-6) alpha-Linolenic acid (ALA; cis-18:3n-3)	missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, polyunsaturated (PUFA)	Arachidonic acid (AA; cis-20:4n-6) DHA (cis-22:6n-3) EPA (cis-20:5n-3) Linoleic acid (LA; cis-18:2n-6) alpha-Linolenic acid (ALA; cis-18:3n-3)	missing unit	19	Pearson	-0.06	>= 0.05	No	Energy by residual method
1665	1657	1724	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, polyunsaturated (PUFA)	Arachidonic acid (AA; cis-20:4n-6) DHA (cis-22:6n-3) EPA (cis-20:5n-3) Linoleic acid (LA; cis-18:2n-6) alpha-Linolenic acid (ALA; cis-18:3n-3)	missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, polyunsaturated (PUFA)	Arachidonic acid (AA; cis-20:4n-6) DHA (cis-22:6n-3) EPA (cis-20:5n-3) Linoleic acid (LA; cis-18:2n-6) alpha-Linolenic acid (ALA; cis-18:3n-3)	missing unit	19	Pearson	-0.07	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1534	1658	1725	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, monounsaturated (MUFA)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, monounsaturated (MUFA)		missing unit	19	Pearson	-0.1	>= 0.05	No
1600	1658	1725	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, monounsaturated (MUFA)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, monounsaturated (MUFA)		missing unit	19	Pearson	-0.1	>= 0.05	No	Energy by residual method
1666	1658	1725	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, monounsaturated (MUFA)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, monounsaturated (MUFA)		missing unit	19	Pearson	0.05	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1535	1659	1726	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, saturated (SFA)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, saturated (SFA)		missing unit	19	Pearson	-0.04	>= 0.05	No
1601	1659	1726	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, saturated (SFA)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, saturated (SFA)		missing unit	19	Pearson	-0.04	>= 0.05	No	Energy by residual method
1667	1659	1726	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, saturated (SFA)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, saturated (SFA)		missing unit	19	Pearson	0.01	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1536	1660	1727	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Linoleic acid (LA; cis-18:2n-6)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Linoleic acid (LA; cis-18:2n-6)		missing unit	19	Pearson	-0.05	>= 0.05	No
1602	1660	1727	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Linoleic acid (LA; cis-18:2n-6)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Linoleic acid (LA; cis-18:2n-6)		missing unit	19	Pearson	-0.05	>= 0.05	No	Energy by residual method
1668	1660	1727	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Linoleic acid (LA; cis-18:2n-6)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Linoleic acid (LA; cis-18:2n-6)		missing unit	19	Pearson	-0.16	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1537	1661	1728	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Arachidonic acid (AA; cis-20:4n-6)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Arachidonic acid (AA; cis-20:4n-6)		missing unit	19	Pearson	-0.05	>= 0.05	No
1603	1661	1728	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Arachidonic acid (AA; cis-20:4n-6)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Arachidonic acid (AA; cis-20:4n-6)		missing unit	19	Pearson	-0.05	>= 0.05	No	Energy by residual method
1669	1661	1728	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Arachidonic acid (AA; cis-20:4n-6)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Arachidonic acid (AA; cis-20:4n-6)		missing unit	19	Pearson	-0.01	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1538	1662	1729	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Linolenic acid (ALA; cis-18:3n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	alpha-Linolenic acid (ALA; cis-18:3n-3)		missing unit	19	Pearson	0.23	>= 0.05	No
1604	1662	1729	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Linolenic acid (ALA; cis-18:3n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	alpha-Linolenic acid (ALA; cis-18:3n-3)		missing unit	19	Pearson	0.23	>= 0.05	No	Energy by residual method
1670	1662	1729	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Linolenic acid (ALA; cis-18:3n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	alpha-Linolenic acid (ALA; cis-18:3n-3)		missing unit	19	Pearson	0.23	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1539	1663	1730	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	EPA (cis-20:5n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	EPA (cis-20:5n-3)		missing unit	19	Pearson	0.22	>= 0.05	No
1605	1663	1730	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	EPA (cis-20:5n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	EPA (cis-20:5n-3)		missing unit	19	Pearson	0.22	>= 0.05	No	Energy by residual method
1671	1663	1730	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	EPA (cis-20:5n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	EPA (cis-20:5n-3)		missing unit	19	Pearson	0.38	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1540	1664	1731	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	DHA (cis-22:6n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	DHA (cis-22:6n-3)		missing unit	19	Pearson	0.04	>= 0.05	No
1606	1664	1731	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	DHA (cis-22:6n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	DHA (cis-22:6n-3)		missing unit	19	Pearson	0.04	>= 0.05	No	Energy by residual method
1672	1664	1731	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	DHA (cis-22:6n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	DHA (cis-22:6n-3)		missing unit	19	Pearson	0.06	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1532	1667	1733	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Selenium		missing unit	baseline; 1 month	Plasma, fasting	Atomic emission spectrometry (AES)	Selenium		missing unit	19	Pearson	-0.41	>= 0.05	No
1598	1667	1733	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Selenium		missing unit	baseline; 1 month	Plasma, fasting	Atomic emission spectrometry (AES)	Selenium		missing unit	19	Pearson	-0.41	>= 0.05	No	Energy by residual method
1664	1667	1733	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Selenium		missing unit	baseline; 1 month	Plasma, fasting	Atomic emission spectrometry (AES)	Selenium		missing unit	19	Pearson	-0.5	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1542	1668	1734	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin C		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Ascorbic acid		missing unit	19	Pearson	0.52	< 0.05	Yes
1608	1668	1734	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin C		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Ascorbic acid		missing unit	19	Pearson	0.52	< 0.05	Yes	Energy by residual method
1674	1668	1734	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin C		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Ascorbic acid		missing unit	19	Pearson	0.51	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1543	1669	1735	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Tocopherol		missing unit	baseline; 1 month	Plasma, fasting	HPLC	alpha-Tocopherol		missing unit	19	Pearson	0.1	>= 0.05	No
1609	1669	1735	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Tocopherol		missing unit	baseline; 1 month	Plasma, fasting	HPLC	alpha-Tocopherol		missing unit	19	Pearson	0.1	>= 0.05	No	Energy by residual method
1675	1669	1735	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Tocopherol		missing unit	baseline; 1 month	Plasma, fasting	HPLC	alpha-Tocopherol		missing unit	19	Pearson	-0.04	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1544	1670	1736	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	gamma-Tocopherol		missing unit	baseline; 1 month	Plasma, fasting	HPLC	gamma-Tocopherol		missing unit	19	Pearson	-0.02	>= 0.05	No
1610	1670	1736	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	gamma-Tocopherol		missing unit	baseline; 1 month	Plasma, fasting	HPLC	gamma-Tocopherol		missing unit	19	Pearson	-0.02	>= 0.05	No	Energy by residual method
1676	1670	1736	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	gamma-Tocopherol		missing unit	baseline; 1 month	Plasma, fasting	HPLC	gamma-Tocopherol		missing unit	19	Pearson	-0.04	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1545	1671	1737	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Lutein/Zeaxanthin		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Lutein/Zeaxanthin		missing unit	19	Pearson	0.72	< 0.01	Yes
1611	1671	1737	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Lutein/Zeaxanthin		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Lutein/Zeaxanthin		missing unit	19	Pearson	0.72	< 0.01	Yes	Energy by residual method
1677	1671	1737	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Lutein/Zeaxanthin		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Lutein/Zeaxanthin		missing unit	19	Pearson	0.76	< 0.01	Yes	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1546	1672	1738	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	beta-Cryptoxanthin		missing unit	baseline; 1 month	Plasma, fasting	HPLC	beta-Cryptoxanthin		missing unit	19	Pearson	0.72	< 0.01	Yes
1612	1672	1738	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	beta-Cryptoxanthin		missing unit	baseline; 1 month	Plasma, fasting	HPLC	beta-Cryptoxanthin		missing unit	19	Pearson	0.72	< 0.01	Yes	Energy by residual method
1678	1672	1738	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	beta-Cryptoxanthin		missing unit	baseline; 1 month	Plasma, fasting	HPLC	beta-Cryptoxanthin		missing unit	19	Pearson	0.64	< 0.05	Yes	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1547	1673	1739	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Carotene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	alpha-Carotene		missing unit	19	Pearson	0.65	< 0.01	Yes
1613	1673	1739	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Carotene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	alpha-Carotene		missing unit	19	Pearson	0.65	< 0.01	Yes	Energy by residual method
1679	1673	1739	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Carotene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	alpha-Carotene		missing unit	19	Pearson	0.73	< 0.01	Yes	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1548	1674	1740	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	beta-Carotene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	beta-Carotene		missing unit	19	Pearson	0.48	< 0.05	Yes
1614	1674	1740	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	beta-Carotene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	beta-Carotene		missing unit	19	Pearson	0.49	< 0.05	Yes	Energy by residual method
1680	1674	1740	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	beta-Carotene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	beta-Carotene		missing unit	19	Pearson	0.71	< 0.01	Yes	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1549	1675	1741	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Lycopene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Lycopene		missing unit	19	Pearson	0.23	>= 0.05	No
1615	1675	1741	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Lycopene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Lycopene		missing unit	19	Pearson	0.23	>= 0.05	No	Energy by residual method
1681	1675	1741	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Lycopene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Lycopene		missing unit	19	Pearson	0.06	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1550	1676	1742	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin B6		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Pyridoxal 5'-phosphate		missing unit	19	Pearson	-0.28	>= 0.05	No
1616	1676	1742	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin B6		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Pyridoxal 5'-phosphate		missing unit	19	Pearson	-0.2	>= 0.05	No	Energy by residual method
1682	1676	1742	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin B6		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Pyridoxal 5'-phosphate		missing unit	19	Pearson	-0.18	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1551	1677	1743	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Folates		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Folates		missing unit	19	Pearson	0.39	>= 0.05	No
1617	1677	1743	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Folates		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Folates		missing unit	19	Pearson	-0.28	>= 0.05	No	Energy by residual method
1683	1677	1743	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Folates		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Folates		missing unit	19	Pearson	-0.29	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1552	1678	1744	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin B12		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Vitamin B12		missing unit	19	Pearson	0.28	>= 0.05	No
1618	1678	1744	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin B12		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Vitamin B12		missing unit	19	Pearson	0.39	>= 0.05	No	Energy by residual method
1684	1678	1744	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin B12		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Vitamin B12		missing unit	19	Pearson	0.42	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1553	1679	1745	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin D		missing unit	baseline; 1 month	Plasma, fasting	HPLC	25-Hydroxycholecalciferol		missing unit	19	Pearson	0.52	< 0.05	Yes
1619	1679	1745	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin D		missing unit	baseline; 1 month	Plasma, fasting	HPLC	25-Hydroxycholecalciferol		missing unit	19	Pearson	0.28	>= 0.05	No	Energy by residual method
1685	1679	1745	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin D		missing unit	baseline; 1 month	Plasma, fasting	HPLC	25-Hydroxycholecalciferol		missing unit	19	Pearson	0.13	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1555	1680	1746	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, polyunsaturated (PUFA)	Arachidonic acid (AA; cis-20:4n-6) DHA (cis-22:6n-3) EPA (cis-20:5n-3) Linoleic acid (LA; cis-18:2n-6) alpha-Linolenic acid (ALA; cis-18:3n-3)	missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, polyunsaturated (PUFA)	Arachidonic acid (AA; cis-20:4n-6) DHA (cis-22:6n-3) EPA (cis-20:5n-3) Linoleic acid (LA; cis-18:2n-6) alpha-Linolenic acid (ALA; cis-18:3n-3)	missing unit	19	Pearson	0.3	>= 0.05	No
1621	1680	1746	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, polyunsaturated (PUFA)	Arachidonic acid (AA; cis-20:4n-6) DHA (cis-22:6n-3) EPA (cis-20:5n-3) Linoleic acid (LA; cis-18:2n-6) alpha-Linolenic acid (ALA; cis-18:3n-3)	missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, polyunsaturated (PUFA)	Arachidonic acid (AA; cis-20:4n-6) DHA (cis-22:6n-3) EPA (cis-20:5n-3) Linoleic acid (LA; cis-18:2n-6) alpha-Linolenic acid (ALA; cis-18:3n-3)	missing unit	19	Pearson	0.3	>= 0.05	No	Energy by residual method
1687	1680	1746	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, polyunsaturated (PUFA)	Arachidonic acid (AA; cis-20:4n-6) DHA (cis-22:6n-3) EPA (cis-20:5n-3) Linoleic acid (LA; cis-18:2n-6) alpha-Linolenic acid (ALA; cis-18:3n-3)	missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, polyunsaturated (PUFA)	Arachidonic acid (AA; cis-20:4n-6) DHA (cis-22:6n-3) EPA (cis-20:5n-3) Linoleic acid (LA; cis-18:2n-6) alpha-Linolenic acid (ALA; cis-18:3n-3)	missing unit	19	Pearson	-0.09	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1556	1681	1747	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, monounsaturated (MUFA)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, monounsaturated (MUFA)		missing unit	19	Pearson	-0.15	>= 0.05	No
1622	1681	1747	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, monounsaturated (MUFA)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, monounsaturated (MUFA)		missing unit	19	Pearson	-0.14	>= 0.05	No	Energy by residual method
1688	1681	1747	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, monounsaturated (MUFA)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, monounsaturated (MUFA)		missing unit	19	Pearson	0.03	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1557	1682	1748	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, saturated (SFA)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, saturated (SFA)		missing unit	19	Pearson	-0.32	>= 0.05	No
1623	1682	1748	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, saturated (SFA)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, saturated (SFA)		missing unit	19	Pearson	-0.32	>= 0.05	No	Energy by residual method
1689	1682	1748	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, saturated (SFA)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, saturated (SFA)		missing unit	19	Pearson	-0.42	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1558	1683	1749	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Linoleic acid (LA; cis-18:2n-6)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Linoleic acid (LA; cis-18:2n-6)		missing unit	19	Pearson	0.23	>= 0.05	No
1624	1683	1749	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Linoleic acid (LA; cis-18:2n-6)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Linoleic acid (LA; cis-18:2n-6)		missing unit	19	Pearson	0.23	>= 0.05	No	Energy by residual method
1690	1683	1749	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Linoleic acid (LA; cis-18:2n-6)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Linoleic acid (LA; cis-18:2n-6)		missing unit	19	Pearson	-0.14	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1559	1684	1750	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Arachidonic acid (AA; cis-20:4n-6)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Arachidonic acid (AA; cis-20:4n-6)		missing unit	19	Pearson	0.1	>= 0.05	No
1625	1684	1750	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Arachidonic acid (AA; cis-20:4n-6)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Arachidonic acid (AA; cis-20:4n-6)		missing unit	19	Pearson	0.1	>= 0.05	No	Energy by residual method
1691	1684	1750	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Arachidonic acid (AA; cis-20:4n-6)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Arachidonic acid (AA; cis-20:4n-6)		missing unit	19	Pearson	0.14	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1560	1685	1751	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Linolenic acid (ALA; cis-18:3n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	alpha-Linolenic acid (ALA; cis-18:3n-3)		missing unit	19	Pearson	0.03	>= 0.05	No
1626	1685	1751	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Linolenic acid (ALA; cis-18:3n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	alpha-Linolenic acid (ALA; cis-18:3n-3)		missing unit	19	Pearson	0.03	>= 0.05	No	Energy by residual method
1692	1685	1751	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Linolenic acid (ALA; cis-18:3n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	alpha-Linolenic acid (ALA; cis-18:3n-3)		missing unit	19	Pearson	-0.12	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1561	1686	1752	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	EPA (cis-20:5n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	EPA (cis-20:5n-3)		missing unit	19	Pearson	0.43	>= 0.05	No
1627	1686	1752	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	EPA (cis-20:5n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	EPA (cis-20:5n-3)		missing unit	19	Pearson	0.43	>= 0.05	No	Energy by residual method
1693	1686	1752	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	EPA (cis-20:5n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	EPA (cis-20:5n-3)		missing unit	19	Pearson	0.41	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1562	1687	1753	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	DHA (cis-22:6n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	DHA (cis-22:6n-3)		missing unit	19	Pearson	0.65	< 0.01	Yes
1628	1687	1753	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	DHA (cis-22:6n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	DHA (cis-22:6n-3)		missing unit	19	Pearson	0.65	< 0.01	Yes	Energy by residual method
1694	1687	1753	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	DHA (cis-22:6n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	DHA (cis-22:6n-3)		missing unit	19	Pearson	0.66	< 0.01	Yes	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1554	1689	1755	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Selenium		missing unit	baseline; 1 month	Plasma, fasting	Atomic emission spectrometry (AES)	Selenium		missing unit	19	Pearson	-0.13	>= 0.05	No
1620	1689	1755	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Selenium		missing unit	baseline; 1 month	Plasma, fasting	Atomic emission spectrometry (AES)	Selenium		missing unit	19	Pearson	-0.13	>= 0.05	No	Energy by residual method
1686	1689	1755	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Selenium		missing unit	baseline; 1 month	Plasma, fasting	Atomic emission spectrometry (AES)	Selenium		missing unit	19	Pearson	-0.14	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1498	1690	1756	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin C		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Ascorbic acid		missing unit	38	Pearson	0.32	>= 0.05	No
1564	1690	1756	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin C		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Ascorbic acid		missing unit	38	Pearson	0.32	>= 0.05	No	Energy by residual method
1630	1690	1756	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin C		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Ascorbic acid		missing unit	38	Pearson	0.3	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1499	1691	1757	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Tocopherol		missing unit	baseline; 1 month	Plasma, fasting	HPLC	alpha-Tocopherol		missing unit	38	Pearson	0.17	>= 0.05	No
1565	1691	1757	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Tocopherol		missing unit	baseline; 1 month	Plasma, fasting	HPLC	alpha-Tocopherol		missing unit	38	Pearson	0.17	>= 0.05	No	Energy by residual method
1631	1691	1757	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Tocopherol		missing unit	baseline; 1 month	Plasma, fasting	HPLC	alpha-Tocopherol		missing unit	38	Pearson	0.11	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1500	1692	1758	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	gamma-Tocopherol		missing unit	baseline; 1 month	Plasma, fasting	HPLC	gamma-Tocopherol		missing unit	38	Pearson	-0.21	>= 0.05	No
1566	1692	1758	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	gamma-Tocopherol		missing unit	baseline; 1 month	Plasma, fasting	HPLC	gamma-Tocopherol		missing unit	38	Pearson	-0.16	>= 0.05	No	Energy by residual method
1632	1692	1758	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	gamma-Tocopherol		missing unit	baseline; 1 month	Plasma, fasting	HPLC	gamma-Tocopherol		missing unit	38	Pearson	-0.15	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1501	1693	1759	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Lutein/Zeaxanthin		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Lutein/Zeaxanthin		missing unit	38	Pearson	0.48	< 0.01	Yes
1567	1693	1759	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Lutein/Zeaxanthin		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Lutein/Zeaxanthin		missing unit	38	Pearson	0.47	< 0.01	Yes	Energy by residual method
1633	1693	1759	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Lutein/Zeaxanthin		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Lutein/Zeaxanthin		missing unit	38	Pearson	0.37	< 0.05	Yes	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1502	1694	1760	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	beta-Cryptoxanthin		missing unit	baseline; 1 month	Plasma, fasting	HPLC	beta-Cryptoxanthin		missing unit	38	Pearson	0.41	< 0.01	Yes
1568	1694	1760	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	beta-Cryptoxanthin		missing unit	baseline; 1 month	Plasma, fasting	HPLC	beta-Cryptoxanthin		missing unit	38	Pearson	0.41	< 0.01	Yes	Energy by residual method
1634	1694	1760	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	beta-Cryptoxanthin		missing unit	baseline; 1 month	Plasma, fasting	HPLC	beta-Cryptoxanthin		missing unit	38	Pearson	0.35	< 0.05	Yes	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1503	1695	1761	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Carotene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	alpha-Carotene		missing unit	38	Pearson	0.49	< 0.01	Yes
1569	1695	1761	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Carotene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	alpha-Carotene		missing unit	38	Pearson	0.49	< 0.01	Yes	Energy by residual method
1635	1695	1761	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Carotene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	alpha-Carotene		missing unit	38	Pearson	0.49	< 0.01	Yes	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1504	1696	1762	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	beta-Carotene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	beta-Carotene		missing unit	38	Pearson	0.43	< 0.01	Yes
1570	1696	1762	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	beta-Carotene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	beta-Carotene		missing unit	38	Pearson	0.43	< 0.01	Yes	Energy by residual method
1636	1696	1762	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	beta-Carotene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	beta-Carotene		missing unit	38	Pearson	0.34	< 0.05	Yes	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1505	1697	1763	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Lycopene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Lycopene		missing unit	38	Pearson	0.12	>= 0.05	No
1571	1697	1763	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Lycopene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Lycopene		missing unit	38	Pearson	0.12	>= 0.05	No	Energy by residual method
1637	1697	1763	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Lycopene		missing unit	baseline; 1 month	Plasma, fasting	HPLC	Lycopene		missing unit	38	Pearson	0.08	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1506	1698	1764	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin B6		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Pyridoxal 5'-phosphate		missing unit	38	Pearson	-0.08	>= 0.05	No
1572	1698	1764	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin B6		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Pyridoxal 5'-phosphate		missing unit	38	Pearson	0.01	>= 0.05	No	Energy by residual method
1638	1698	1764	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin B6		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Pyridoxal 5'-phosphate		missing unit	38	Pearson	0.01	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1507	1699	1765	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Folates		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Folates		missing unit	38	Pearson	0.04	>= 0.05	No
1573	1699	1765	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Folates		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Folates		missing unit	38	Pearson	-0.08	>= 0.05	No	Energy by residual method
1639	1699	1765	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Folates		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Folates		missing unit	38	Pearson	-0.1	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1508	1700	1766	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin B12		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Vitamin B12		missing unit	38	Pearson	0.19	>= 0.05	No
1574	1700	1766	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin B12		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Vitamin B12		missing unit	38	Pearson	0.04	>= 0.05	No	Energy by residual method
1640	1700	1766	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin B12		missing unit	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Vitamin B12		missing unit	38	Pearson	0.14	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1509	1701	1767	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin D		missing unit	baseline; 1 month	Plasma, fasting	HPLC	25-Hydroxycholecalciferol		missing unit	38	Pearson	0.32	>= 0.05	No
1575	1701	1767	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin D		missing unit	baseline; 1 month	Plasma, fasting	HPLC	25-Hydroxycholecalciferol		missing unit	38	Pearson	0.19	>= 0.05	No	Energy by residual method
1641	1701	1767	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Vitamin D		missing unit	baseline; 1 month	Plasma, fasting	HPLC	25-Hydroxycholecalciferol		missing unit	38	Pearson	0.16	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1511	1702	1768	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, polyunsaturated (PUFA)	Arachidonic acid (AA; cis-20:4n-6) DHA (cis-22:6n-3) EPA (cis-20:5n-3) Linoleic acid (LA; cis-18:2n-6) alpha-Linolenic acid (ALA; cis-18:3n-3)	missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, polyunsaturated (PUFA)	Arachidonic acid (AA; cis-20:4n-6) DHA (cis-22:6n-3) EPA (cis-20:5n-3) Linoleic acid (LA; cis-18:2n-6) alpha-Linolenic acid (ALA; cis-18:3n-3)	missing unit	38	Pearson	0.1	>= 0.05	No
1577	1702	1768	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, polyunsaturated (PUFA)	Arachidonic acid (AA; cis-20:4n-6) DHA (cis-22:6n-3) EPA (cis-20:5n-3) Linoleic acid (LA; cis-18:2n-6) alpha-Linolenic acid (ALA; cis-18:3n-3)	missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, polyunsaturated (PUFA)	Arachidonic acid (AA; cis-20:4n-6) DHA (cis-22:6n-3) EPA (cis-20:5n-3) Linoleic acid (LA; cis-18:2n-6) alpha-Linolenic acid (ALA; cis-18:3n-3)	missing unit	38	Pearson	0.1	>= 0.05	No	Energy by residual method
1643	1702	1768	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, polyunsaturated (PUFA)	Arachidonic acid (AA; cis-20:4n-6) DHA (cis-22:6n-3) EPA (cis-20:5n-3) Linoleic acid (LA; cis-18:2n-6) alpha-Linolenic acid (ALA; cis-18:3n-3)	missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, polyunsaturated (PUFA)	Arachidonic acid (AA; cis-20:4n-6) DHA (cis-22:6n-3) EPA (cis-20:5n-3) Linoleic acid (LA; cis-18:2n-6) alpha-Linolenic acid (ALA; cis-18:3n-3)	missing unit	38	Pearson	0.0	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1512	1703	1769	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, monounsaturated (MUFA)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, monounsaturated (MUFA)		missing unit	38	Pearson	-0.15	>= 0.05	No
1578	1703	1769	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, monounsaturated (MUFA)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, monounsaturated (MUFA)		missing unit	38	Pearson	-0.15	>= 0.05	No	Energy by residual method
1644	1703	1769	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, monounsaturated (MUFA)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, monounsaturated (MUFA)		missing unit	38	Pearson	-0.07	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1513	1704	1770	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, saturated (SFA)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, saturated (SFA)		missing unit	38	Pearson	-0.13	>= 0.05	No
1579	1704	1770	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, saturated (SFA)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, saturated (SFA)		missing unit	38	Pearson	-0.13	>= 0.05	No	Energy by residual method
1645	1704	1770	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Fatty acids, saturated (SFA)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, saturated (SFA)		missing unit	38	Pearson	-0.11	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1514	1705	1771	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Linoleic acid (LA; cis-18:2n-6)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Linoleic acid (LA; cis-18:2n-6)		missing unit	38	Pearson	0.09	>= 0.05	No
1580	1705	1771	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Linoleic acid (LA; cis-18:2n-6)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Linoleic acid (LA; cis-18:2n-6)		missing unit	38	Pearson	0.07	>= 0.05	No	Energy by residual method
1646	1705	1771	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Linoleic acid (LA; cis-18:2n-6)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Linoleic acid (LA; cis-18:2n-6)		missing unit	38	Pearson	-0.07	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1515	1706	1772	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Arachidonic acid (AA; cis-20:4n-6)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Arachidonic acid (AA; cis-20:4n-6)		missing unit	38	Pearson	0.01	>= 0.05	No
1581	1706	1772	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Arachidonic acid (AA; cis-20:4n-6)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Arachidonic acid (AA; cis-20:4n-6)		missing unit	38	Pearson	-0.01	>= 0.05	No	Energy by residual method
1647	1706	1772	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Arachidonic acid (AA; cis-20:4n-6)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	Arachidonic acid (AA; cis-20:4n-6)		missing unit	38	Pearson	0.03	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1516	1707	1773	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Linolenic acid (ALA; cis-18:3n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	alpha-Linolenic acid (ALA; cis-18:3n-3)		missing unit	38	Pearson	0.15	>= 0.05	No
1582	1707	1773	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Linolenic acid (ALA; cis-18:3n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	alpha-Linolenic acid (ALA; cis-18:3n-3)		missing unit	38	Pearson	0.15	>= 0.05	No	Energy by residual method
1648	1707	1773	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	alpha-Linolenic acid (ALA; cis-18:3n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	alpha-Linolenic acid (ALA; cis-18:3n-3)		missing unit	38	Pearson	0.14	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1517	1708	1774	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	EPA (cis-20:5n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	EPA (cis-20:5n-3)		missing unit	38	Pearson	0.39	< 0.05	Yes
1583	1708	1774	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	EPA (cis-20:5n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	EPA (cis-20:5n-3)		missing unit	38	Pearson	0.39	< 0.05	Yes	Energy by residual method
1649	1708	1774	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	EPA (cis-20:5n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	EPA (cis-20:5n-3)		missing unit	38	Pearson	0.39	< 0.05	Yes	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1518	1709	1775	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	DHA (cis-22:6n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	DHA (cis-22:6n-3)		missing unit	38	Pearson	0.39	< 0.05	Yes
1584	1709	1775	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	DHA (cis-22:6n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	DHA (cis-22:6n-3)		missing unit	38	Pearson	0.39	< 0.05	Yes	Energy by residual method
1650	1709	1775	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	DHA (cis-22:6n-3)		missing unit	baseline; 1 month	Plasma, fasting	GC-FID	DHA (cis-22:6n-3)		missing unit	38	Pearson	0.38	< 0.05	Yes	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol
1510	1711	1777	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Selenium		missing unit	baseline; 1 month	Plasma, fasting	Atomic emission spectrometry (AES)	Selenium		missing unit	38	Pearson	-0.33	< 0.05	Yes
1576	1711	1777	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Selenium		missing unit	baseline; 1 month	Plasma, fasting	Atomic emission spectrometry (AES)	Selenium		missing unit	38	Pearson	-0.33	< 0.05	Yes	Energy by residual method
1642	1711	1777	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline	Food Frequency Questionnaire (FFQ)	Selenium		missing unit	baseline; 1 month	Plasma, fasting	Atomic emission spectrometry (AES)	Selenium		missing unit	38	Pearson	-0.32	>= 0.05	No	Energy by residual method	Age, Sex, ApoE genotype, Cholesterol

Reproducibility values

ID	Mst. ID	Subject group	Population	Country	Country code	Time definition	Biological specimen	Experimental method	Biomarker	Biomarker detail	Unit	Reproducibility size	ICC
31	1767	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	25-Hydroxycholecalciferol		missing unit	38	0.98
32	1760	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	beta-Cryptoxanthin		missing unit	38	0.97
33	1766	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Vitamin B12		missing unit	38	0.97
34	1759	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	Lutein/Zeaxanthin		missing unit	38	0.96
35	1757	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	alpha-Tocopherol		missing unit	38	0.95
36	1761	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	alpha-Carotene		missing unit	38	0.94
37	1763	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	Lycopene		missing unit	38	0.92
38	1765	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Folates		missing unit	38	0.92
39	1762	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	beta-Carotene		missing unit	38	0.88
40	1758	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	gamma-Tocopherol		missing unit	38	0.84
41	1764	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Pyridoxal 5'-phosphate		missing unit	38	0.8
42	1756	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	Ascorbic acid		missing unit	38	0.49
43	1777	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	Atomic emission spectrometry (AES)	Selenium		missing unit	38	0.55
44	1775	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	DHA (cis-22:6n-3)		missing unit	38	0.92
45	1774	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	EPA (cis-20:5n-3)		missing unit	38	0.92
46	1768	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, polyunsaturated (PUFA)	Arachidonic acid (AA; cis-20:4n-6) DHA (cis-22:6n-3) EPA (cis-20:5n-3) Linoleic acid (LA; cis-18:2n-6) alpha-Linolenic acid (ALA; cis-18:3n-3)	missing unit	38	0.92
47	1771	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	Linoleic acid (LA; cis-18:2n-6)		missing unit	38	0.87
48	1770	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, saturated (SFA)		missing unit	38	0.82
49	1772	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	Arachidonic acid (AA; cis-20:4n-6)		missing unit	38	0.79
50	1769	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, monounsaturated (MUFA)		missing unit	38	0.79
51	1773	All [by diagnosis]	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	alpha-Linolenic acid (ALA; cis-18:3n-3)		missing unit	38	0.7
53	1738	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	beta-Cryptoxanthin		missing unit	19	0.99
54	1745	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	25-Hydroxycholecalciferol		missing unit	19	0.98
55	1737	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	Lutein/Zeaxanthin		missing unit	19	0.97
56	1753	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	DHA (cis-22:6n-3)		missing unit	19	0.97
57	1744	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Vitamin B12		missing unit	19	0.97
58	1735	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	alpha-Tocopherol		missing unit	19	0.97
60	1752	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	EPA (cis-20:5n-3)		missing unit	19	0.94
61	1741	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	Lycopene		missing unit	19	0.94
62	1743	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Folates		missing unit	19	0.93
63	1746	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, polyunsaturated (PUFA)	Arachidonic acid (AA; cis-20:4n-6) DHA (cis-22:6n-3) EPA (cis-20:5n-3) Linoleic acid (LA; cis-18:2n-6) alpha-Linolenic acid (ALA; cis-18:3n-3)	missing unit	19	0.92
64	1750	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	Arachidonic acid (AA; cis-20:4n-6)		missing unit	19	0.9
65	1749	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	Linoleic acid (LA; cis-18:2n-6)		missing unit	19	0.9
66	1748	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, saturated (SFA)		missing unit	19	0.87
67	1739	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	alpha-Carotene		missing unit	19	0.86
68	1740	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	beta-Carotene		missing unit	19	0.85
69	1747	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, monounsaturated (MUFA)		missing unit	19	0.84
70	1751	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	alpha-Linolenic acid (ALA; cis-18:3n-3)		missing unit	19	0.81
71	1742	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Pyridoxal 5'-phosphate		missing unit	19	0.77
72	1736	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	gamma-Tocopherol		missing unit	19	0.75
73	1755	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	Atomic emission spectrometry (AES)	Selenium		missing unit	19	0.48
74	1734	No cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	Ascorbic acid		missing unit	19	0.1
75	1716	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	beta-Cryptoxanthin		missing unit	19	0.95
76	1723	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	25-Hydroxycholecalciferol		missing unit	19	0.98
77	1715	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	Lutein/Zeaxanthin		missing unit	19	0.94
78	1731	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	DHA (cis-22:6n-3)		missing unit	19	0.86
79	1722	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Vitamin B12		missing unit	19	0.94
80	1713	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	alpha-Tocopherol		missing unit	19	0.9
82	1730	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	EPA (cis-20:5n-3)		missing unit	19	0.87
83	1719	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	Lycopene		missing unit	19	0.89
84	1721	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Folates		missing unit	19	0.92
85	1724	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, polyunsaturated (PUFA)	Arachidonic acid (AA; cis-20:4n-6) DHA (cis-22:6n-3) EPA (cis-20:5n-3) Linoleic acid (LA; cis-18:2n-6) alpha-Linolenic acid (ALA; cis-18:3n-3)	missing unit	19	0.92
86	1728	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	Arachidonic acid (AA; cis-20:4n-6)		missing unit	19	0.73
87	1727	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	Linoleic acid (LA; cis-18:2n-6)		missing unit	19	0.91
88	1726	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, saturated (SFA)		missing unit	19	0.78
89	1717	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	alpha-Carotene		missing unit	19	0.89
90	1718	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	beta-Carotene		missing unit	19	0.97
91	1725	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	Fatty acids, monounsaturated (MUFA)		missing unit	19	0.71
92	1729	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	GC-FID	alpha-Linolenic acid (ALA; cis-18:3n-3)		missing unit	19	0.6
93	1720	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	Radioimmunoassay	Pyridoxal 5'-phosphate		missing unit	19	0.94
94	1714	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	gamma-Tocopherol		missing unit	19	0.83
95	1733	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	Atomic emission spectrometry (AES)	Selenium		missing unit	19	0.58
96	1712	Mild cognitive impairment	Elderly subjects with and without mild cognitive impairment	United States	US	baseline; 1 month	Plasma, fasting	HPLC	Ascorbic acid		missing unit	19	0.69