ID1052
NamePCB-101
Synonyms2,2',4,5,5'-Pentachlorobiphenyl
StructureThumb
Description
ClassificationCompounds > Pollution > Air and water pollutants > Polychlorinated biphenyls (PCB)
CAS number37680-73-2
PubChem ID37807
ChEBI ID
FooDB ID
HMDB ID

Chemical data

MolDBi data

IUPAC Name1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene
Traditional IUPAC Namepentachlorobiphenyl
FormulaC12H5Cl5
InChIInChI=1S/C12H5Cl5/c13-6-1-2-9(14)7(3-6)8-4-11(16)12(17)5-10(8)15/h1-5H
InChI KeyLAHWLEDBADHJGA-UHFFFAOYSA-N
Molecular weight326.433
Exact mass323.883388695
SMILESClC1=CC=C(Cl)C(=C1)C1=CC(Cl)=C(Cl)C=C1Cl

ClassyFire Taxonomy

Description belongs to the class of organic compounds known as polychlorinated biphenyls. These are organic compounds containing at least two chlorine atoms attached to either benzene ring of the biphenyl moiety.
KingdomOrganic compounds
Super ClassBenzenoids
ClassBenzene and substituted derivatives
Sub ClassBiphenyls and derivatives
Direct ParentPolychlorinated biphenyls
Alternative Parents

Publications with PCB-101

TitleFirst authorYear
Concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and polychlorinated biphenyls in blood and breast milk collected from pregnant women in Sapporo City, JapanTodaka2011
Distribution of PCDD/Fs, PCBs, PBDEs and organochlorine residues in children’s blood from Zhejiang, ChinaShen2010
Relationship between the concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and polychlorinated biphenyls in maternal blood and those in breast milkTodaka2010
PCDD/F and PCB in human serum of differently exposed population groups of an Italian cityTurrio-Baldassarri2008
Distribution of polybrominated diphenyl ethers (PBDEs) and other persistent organic pollutants in human serum from GreeceKalantzi2011
Assessment of the levels of persistent organic pollutants and 1-hydroxypyrene in blood and urine samples from Mexican children living in an endemic malaria area in MexicoTrejo-Acevedo2012
Biological monitoring of indoor-exposure to dioxin-like and non-dioxin-like polychlorinated biphenyls (PCB) in a public buildingSchettgen2012
Background levels of polychlorinated biphenyls in the population of the Canary Islands (Spain)Henriquez-Hernandez2011
Caffeine N3-demethylation (CYP1A2) in a population with an increased exposure to polychlorinated biphenylsPetersen2006
Blood pressure in relation to concentrations of PCB congeners and chlorinated pesticidesGoncharov2011
Associations between prenatal exposure to polychlorinated biphenyls and neonatal thyroid-stimulating hormone levels in a Mexican-American population, Salinas Valley, CaliforniaChevrier2007
Assessment of exposure to polychlorinated biphenyls: analysis of selected isomers in blood and adipose tissueLuotamo1991
Exposure to polychlorinated biphenyl (PCB) congeners measured shortly after giving birth and subsequent risk of maternal breast cancer before age 50Cohn2012
Determinants of serum concentrations of 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene and polychlorinated biphenyls among French women in the CECILE studyBachelet2011
In utero exposure to polychlorinated biphenyls and reduced neonatal physiological development from Guiyu, ChinaWu2011
Distribution of PCBs, their hydroxylated metabolites, and other phenolic contaminants in human serum from two European countriesDirtu2010
Concentrations of polychlorinated biphenyls in blood of Yusho patients over 35 years after the incidentTodaka2009
Distribution of organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) in human serum from urban areas in KoreaKang2008
Distribution of polychlorinated biphenyls and organochlorine pesticides in human breast milk from various locations in Tunisia: Levels of contamination, influencing factors, and infant risk assessmentEnnaceur2008
Effects of exposure to polychlorinated biphenyls and organochlorine pesticides on thyroid function during pregnancyChevrier2008
Congener-specific approach to human PCB concentrations by serum analysisPark2007
Concentrations of polychlorinated biphenyls in blood and the risk for testicular cancerHardell2004
Human exposure to polychlorinated biphenyls in a residential communityOrloff2003
Congener-specific analysis of polychlorinated biphenyl in human blood from JapaneseHirai2005
Environmental exposure to PCBs and cancer incidence in eastern SlovakiaPavuk2004
Exposure patterns of UV filters, fragrances, parabens, phthalates, organochlor pesticides, PBDEs, and PCBs in human milk: Correlation of UV filters with use of cosmeticsSchlumpf2010

Biomarker data

Measurements of PCB-101 in biospecimens

Concentration values

IDParent IDDepthSubject groupPopulationCountryCohortBiomarker Time definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianConverted unitAdjustment typeAdjusted onRegressed onExpressed asPublication

Reproducibility values

IDExcretion IDSubject groupPopulationCountryCohortBiomarker Time definitionBiospecimenAnalytical methodBiomarkerBiomarker detailArithmetic meanGeometric meanMedianUnitAdjusted onReproducibility sizeICCICC 95% CI lowerICC 95% CI upperCV% WSCV% BSVAR WSVAR BSPublication

Associations of PCB-101 with exposures

Correlation values

IDIntake IDExcretion IDSubject groupPopulationCountryCohortIntake Time definitionIntake Assessment methodIntakeIntake detailSupplement intakes included?Intake Arithmetic meanIntake Geometric meanIntake MedianIntake UnitIntake Adjusted onBiomarker Time definitionBiospecimenAnalytical methodBiomarkerBiomarker detailBiomarker Arithmetic meanBiomarker Geometric meanBiomarker MedianBiomarker UnitBiomarker Adjusted onCorrelation sizeCorrelation typeCorrelation valueCorrelation 95% CI lowerCorrelation 95% CI upperCorrelation p-valueSignificant?Measurement adjustmentDeattenuated?CovariatesPublication

Metabolomic associations

IDIntake IDExcretion IDSubject groupPopulationCountryCohortNo. of subjectsIntake Assessment methodIntakeIntervention doseBiospecimenAnalytical methodBiomarkerStructural identificationFeature selectionArea under curveSensitivitySpecificityPLS-DA VIPBeta coefficientBeta coefficient p-valueANOVA p-valuePublication

Associations of PCB-101 with cancer risk

Cancer associations

IDExcretion IDSubject groupPopulationCountryCohortNo. of subjectsNo. of casesNo. of controlsBiospecimenAnalytical methodBiomarkerBiomarker detailCancerStudy designPublication

Exposure data

Measurements of PCB-101 exposures in populations

Intake values

IDParent IDDepthSubject groupPopulationCountryCohortIntake Time definitionIntake assessment toolIntake food coverageIntake time coverageIntake Assessment methodIntakeIntake detailFood descriptionSupplement intakes included?Measurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianConverted unitAdjustment typeAdjusted onRegressed onExpressed asPublication

Associations of PCB-101 exposures with biomarkers

Correlation values

IDIntake IDExcretion IDSubject groupPopulationCountryCohortIntake Time definitionIntake Assessment methodIntakeIntake detailSupplement intakes included?Intake Arithmetic meanIntake Geometric meanIntake MedianIntake UnitIntake Adjusted onBiomarker Time definitionBiospecimenAnalytical methodBiomarkerBiomarker detailBiomarker Arithmetic meanBiomarker Geometric meanBiomarker MedianBiomarker UnitBiomarker Adjusted onCorrelation sizeCorrelation typeCorrelation valueCorrelation 95% CI lowerCorrelation 95% CI upperCorrelation p-valueSignificant?Measurement adjustmentDeattenuated?CovariatesPublication