ID951
NamePCB-189
Synonyms2,3,3',4,4',5,5'-Heptachlorobiphenyl
StructureThumb
Description
ClassificationCompounds > Pollution > Air and water pollutants > Polychlorinated biphenyls (PCB)
CAS number39635-31-9
PubChem ID38306
ChEBI ID81525
FooDB ID
HMDB ID

Chemical data

MolDBi data

IUPAC Name1,2,3,4-tetrachloro-5-(3,4,5-trichlorophenyl)benzene
Traditional IUPAC Name1,2,3,4-tetrachloro-5-(3,4,5-trichlorophenyl)benzene
FormulaC12H3Cl7
InChIInChI=1S/C12H3Cl7/c13-6-1-4(2-7(14)10(6)17)5-3-8(15)11(18)12(19)9(5)16/h1-3H
InChI KeyXUAWBXBYHDRROL-UHFFFAOYSA-N
Molecular weight395.323
Exact mass391.805444045
SMILESClC1=CC(=CC(Cl)=C1Cl)C1=CC(Cl)=C(Cl)C(Cl)=C1Cl

ClassyFire Taxonomy

Description belongs to the class of organic compounds known as polychlorinated biphenyls. These are organic compounds containing at least two chlorine atoms attached to either benzene ring of the biphenyl moiety.
KingdomOrganic compounds
Super ClassBenzenoids
ClassBenzene and substituted derivatives
Sub ClassBiphenyls and derivatives
Direct ParentPolychlorinated biphenyls
Alternative Parents

Publications with PCB-189

TitleFirst authorYear
PCDD, PCDF, and PCB exposure in current and former firefighters from Eastern SiberiaChernyak2012
Concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and polychlorinated biphenyls in blood and breast milk collected from pregnant women in Sapporo City, JapanTodaka2011
Longitudinal increases in PCDD/F and dl-PCB concentrations in human milk in northern ChinaSun2011
Distribution of PCDD/Fs, PCBs, PBDEs and organochlorine residues in children’s blood from Zhejiang, ChinaShen2010
Relationship between the concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and polychlorinated biphenyls in maternal blood and those in breast milkTodaka2010
Serum levels of polychlorinated dibenzodioxins and dibenzofurans and PCBs in the general population living near an urban waste treatment plant in Biscay, Basque CountryZubero2009
Evaluation of background persistent organic pollutant levels in human from Taiwan: Polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenylsHsu2009
PCDD/F and PCB in human serum of differently exposed population groups of an Italian cityTurrio-Baldassarri2008
PCDD/F and dioxin-like PCB in human blood and milk from German mothersWittsiepe2007
Biological monitoring of indoor-exposure to dioxin-like and non-dioxin-like polychlorinated biphenyls (PCB) in a public buildingSchettgen2012
Background levels of polychlorinated biphenyls in the population of the Canary Islands (Spain)Henriquez-Hernandez2011
Blood pressure in relation to concentrations of PCB congeners and chlorinated pesticidesGoncharov2011
Estimation of age- and sex-specific background human serum concentrations of PCDDs, PCDFs, and PCBs in the UMDES and NHANES populationsChen2013
Correlations of fish intake and plasma docosahexaenoic acid levels with each congener of PCDDs/PCDFs/dioxin-like PCBs in blood from the Japanese populationKitayama2011
In utero exposure to polychlorinated biphenyls and reduced neonatal physiological development from Guiyu, ChinaWu2011
Concentrations of polychlorinated biphenyls in blood of Yusho patients over 35 years after the incidentTodaka2009
Determination of dioxins and polychlorinated biphenyls in breast milk, maternal blood and cord blood from residents of Tohoku, JapanNakamura2008
Congener-specific approach to human PCB concentrations by serum analysisPark2007
Concentrations of polychlorinated biphenyls in blood and the risk for testicular cancerHardell2004
Human exposure to polychlorinated biphenyls in a residential communityOrloff2003
Effects of prenatal exposure to polychlorinated biphenyls and dioxins on mental and motor development in Japanese children at 6 months of ageNakajima2006
Congener-specific analysis of polychlorinated biphenyl in human blood from JapaneseHirai2005
Environmental exposure to PCBs and cancer incidence in eastern SlovakiaPavuk2004
Fish intake, plasma omega-3 polyunsaturated fatty acids, and polychlorinated dibenzo-p-dioxins/polychlorinated dibenzo-furans and co-planar polychlorinated biphenyls in the blood of the Japanese populationArisawa2003

Biomarker data

Measurements of PCB-189 in biospecimens

Concentration values

IDParent IDDepthSubject groupPopulationCountryCohortBiomarker Time definitionBiospecimenAnalytical methodBiomarkerBiomarker detailMeasurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianConverted unitAdjustment typeAdjusted onRegressed onExpressed asPublication

Reproducibility values

IDExcretion IDSubject groupPopulationCountryCohortBiomarker Time definitionBiospecimenAnalytical methodBiomarkerBiomarker detailArithmetic meanGeometric meanMedianUnitAdjusted onReproducibility sizeICCICC 95% CI lowerICC 95% CI upperCV% WSCV% BSVAR WSVAR BSPublication

Associations of PCB-189 with exposures

Correlation values

IDIntake IDExcretion IDSubject groupPopulationCountryCohortIntake Time definitionIntake Assessment methodIntakeIntake detailSupplement intakes included?Intake Arithmetic meanIntake Geometric meanIntake MedianIntake UnitIntake Adjusted onBiomarker Time definitionBiospecimenAnalytical methodBiomarkerBiomarker detailBiomarker Arithmetic meanBiomarker Geometric meanBiomarker MedianBiomarker UnitBiomarker Adjusted onCorrelation sizeCorrelation typeCorrelation valueCorrelation 95% CI lowerCorrelation 95% CI upperCorrelation p-valueSignificant?Measurement adjustmentDeattenuated?CovariatesPublication

Metabolomic associations

IDIntake IDExcretion IDSubject groupPopulationCountryCohortNo. of subjectsIntake Assessment methodIntakeIntervention doseBiospecimenAnalytical methodBiomarkerStructural identificationFeature selectionArea under curveSensitivitySpecificityPLS-DA VIPBeta coefficientBeta coefficient p-valueANOVA p-valuePublication

Associations of PCB-189 with cancer risk

Cancer associations

IDExcretion IDSubject groupPopulationCountryCohortNo. of subjectsNo. of casesNo. of controlsBiospecimenAnalytical methodBiomarkerBiomarker detailCancerStudy designPublication

Exposure data

Measurements of PCB-189 exposures in populations

Intake values

IDParent IDDepthSubject groupPopulationCountryCohortIntake Time definitionIntake assessment toolIntake food coverageIntake time coverageIntake Assessment methodIntakeIntake detailFood descriptionSupplement intakes included?Measurement sizeDetected (nb)Detected (%)Detected only?Arithmethic meanArithmethic SDGeometric meanGeometric SDMinMin (detected)Percentile_05Percentile_10Percentile_25MedianPercentile_75Percentile_90Percentile_95MaxInterquartile rangeMean 95% CI lowerMean 95% CI upperGMean 95% CI lowerGMean 95% CI upperUnitConverted arithmetic meanConverted geometric meanConverted medianConverted unitAdjustment typeAdjusted onRegressed onExpressed asPublication

Associations of PCB-189 exposures with biomarkers

Correlation values

IDIntake IDExcretion IDSubject groupPopulationCountryCohortIntake Time definitionIntake Assessment methodIntakeIntake detailSupplement intakes included?Intake Arithmetic meanIntake Geometric meanIntake MedianIntake UnitIntake Adjusted onBiomarker Time definitionBiospecimenAnalytical methodBiomarkerBiomarker detailBiomarker Arithmetic meanBiomarker Geometric meanBiomarker MedianBiomarker UnitBiomarker Adjusted onCorrelation sizeCorrelation typeCorrelation valueCorrelation 95% CI lowerCorrelation 95% CI upperCorrelation p-valueSignificant?Measurement adjustmentDeattenuated?CovariatesPublication